This special volume of "Progress in Molecular Biology and Translational Science" provides a current overview of how memory is processed in the brain.A broad range of topics are presented by leaders in the field, ranging from brain circuitry to synaptic plasticity to the molecular machinery that contributes to the brain's ability to maintain information across time. Memory systems in the prefrontal cortex, hippocampus and amygdala are considered as well. In addition, the volume covers recent contributions to our understanding of memory from in vivo imaging, optogenetic, electrophysiological, biochemical and molecular biological studies.
Articles from world renowned experts in memoryCovering topics from signaling, epigenetic, RNA translation to plasticityMethodological approaches includemolecular and cellular, behavioral, electrophysiological, optogenetic and functional imaging"

The book discusses India's evolving deterrent force posturing in South Asia under the conceptual essentials of nuclear revolution when it comes to various combinations of conventional and nuclear forces development and the strategic implications it intentionally or unintentionally poses for the South Asian region. The book talks about how the contemporary restructuring of India's deterrent force posture affects India's nuclear strategy, in general, and how this in turn could affect the policies of its adversaries: China and Pakistan, in particular. Authors discuss the motivations of such posturing that broadly covers India's restructuring of its Nuclear Draft Doctrine (DND), the ballistic missile development program, including that of its Ballistic Missile Defence (BMD) system, and the possibility of conflicts between China-India and India-Pakistan, given their transforming strategic force postures and their recurring adversarial behavior against each other in the Southern Asian region.

This book explores evolving patterns of nuclear deterrence, the impact of new technologies, and changing deterrent force postures in the South Asian region to assess future challenges for sustainable peace and stability. Under the core principles of the security dilemma, this book analyzes the prevailing security environment in South Asia and offers unilateral, bilateral, and multilateral frameworks to stabilize peace and ensure deterrence stability in the South Asian region. Moreover, contending patterns of deterrence dynamics in the South Asian region are further elaborated as becoming inextricably interlinked with the broader security dynamics of the Asia-Pacific region and the interactions with the United States and China's Belt and Road Initiative. As India and Pakistan are increasingly becoming part of the competing strategies exercised by the United States and China, the authors analyze how strategic uncertainty and fear faced by these rival states cause the introduction of new technologies which could gradually drift these competing states into more serious crises and military conflicts. Presenting innovative solutions to emerging South Asian challenges and offering new security mechanisms for sustainable peace and stability, this book will be of interest to academics and policymakers working on Asian Security studies, Nuclear Strategy, and International Relations.

This book explores evolving patterns of nuclear deterrence, the impact of new technologies, and changing deterrent force postures in the South Asian region to assess future challenges for sustainable peace and stability. Under the core principles of the security dilemma, this book analyzes the prevailing security environment in South Asia and offers unilateral, bilateral, and multilateral frameworks to stabilize peace and ensure deterrence stability in the South Asian region. Moreover, contending patterns of deterrence dynamics in the South Asian region are further elaborated as becoming inextricably interlinked with the broader security dynamics of the Asia-Pacific region and the interactions with the United States and China's Belt and Road Initiative. As India and Pakistan are increasingly becoming part of the competing strategies exercised by the United States and China, the authors analyze how strategic uncertainty and fear faced by these rival states cause the introduction of new technologies which could gradually drift these competing states into more serious crises and military conflicts. Presenting innovative solutions to emerging South Asian challenges and offering new security mechanisms for sustainable peace and stability, this book will be of interest to academics and policymakers working on Asian Security studies, Nuclear Strategy, and International Relations.

In May 1998, in reaction to India's nuclear weapons tests, Pakistan tested six nuclear weapons. Following this, the country opted for a policy of minimum deterrence, and within a year Pakistan had altered its policy stance by adding the modifier of minimum 'credible' deterrence. This book looks at how this seemingly innocuous shift seriously impacted on Pakistan's nuclear policy direction and whether the concept of minimum has lost its significance in the South Asian region's changed/changing strategic environment. After providing a brief historical background exploring why and how Pakistan carried out the nuclear development program, the book questions why Pakistan could not sustain the minimum deterrence that it had conceptualized in the immediate aftermath of the 1998 test. It examines the conceptual theoretical framework of the essentials of minimum deterrence in order to question whether Pakistan's nuclear policy remained consistent with this, as well as to discover the rudimentary factors that are responsible for the inconsistencies with regard to minimum deterrence conceived in this study. The book goes on to look at the policy options that Pakistan had after acquiring the nuclear capability, and what the rationale was for selecting minimum deterrence. The book not only highlights Pakistan deterrent force building, but also analyzes closely Pakistan's doctrinal posture of first use option. Furthermore, it examines the policy towards arms control and disarmament, and discusses whether these individual policy orientations are consistent with the minimum deterrence. Conceptually providing a deeper understanding of Pakistan's post-1998 nuclear policy, this book critically examines whether the minimum deterrence conceived could be sustained both at the theoretical and operational levels. It will be a useful contribution in the field of Nuclear Policy, Security Studies, Asian Politics, Proliferation/Non-Proliferation Studies, and Peace Studies. This book will be of interest to policy makers, scholars, and students of nuclear policy, nuclear proliferation and arms control related research.

In May 1998, in reaction to India s nuclear weapons tests, Pakistan tested six nuclear weapons. Following this, the country opted for a policy of minimum deterrence, and within a year Pakistan had altered its policy stance by adding the modifier of minimum credible deterrence. This book looks at how this seemingly innocuous shift seriously impacted on Pakistan s nuclear policy direction and whether the concept of minimum has lost its significance in the South Asian region s changed/changing strategic environment.

After providing a brief historical background exploring why and how Pakistan carried out the nuclear development program, the book questions why Pakistan could not sustain the minimum deterrence that it had conceptualized in the immediate aftermath of the 1998 test. It examines the conceptual theoretical framework of the essentials of minimum deterrence in order to question whether Pakistan s nuclear policy remained consistent with this, as well as to discover the rudimentary factors that are responsible for the inconsistencies with regard to minimum deterrence conceived in this study. The book goes on to look at the policy options that Pakistan had after acquiring the nuclear capability, and what the rationale was for selecting minimum deterrence. The book not only highlights Pakistan deterrent force building, but also analyzes closely Pakistan s doctrinal posture of first use option. Furthermore, it examines the policy towards arms control and disarmament, and discusses whether these individual policy orientations are consistent with the minimum deterrence.

Conceptually providing a deeper understanding of Pakistan s post-1998 nuclear policy, this book critically examines whether the minimum deterrence conceived could be sustained both at the theoretical and operational levels. It will be a useful contribution in the field of Nuclear Policy, Security Studies, Asian Politics, Proliferation/Non-Proliferation Studies, and Peace Studies. This book will be of interest to policy makers, scholars, and students of nuclear policy, nuclear proliferation and arms control related research. "

Labor productivity plays an important role in the successful delivery of construction projects. It is substantially important to understand the nature and extent to which certain factors affect productivity. A field study conducted to examine a set of parameters that impact labor productivity on building construction jobsites is presented. These parameters include temperature, relative humidity, wind speed, precipitation, gang size, crew composition, height of work, type of work and the method employed. Techniques from inferential statistics and artificial intelligence such as Fuzzy subtractive clustering, neural network modeling and stepwise variable selection procedure are used to analyze and determine the relative importance and contribution of each parameter towards productivity estimates. Required data was collected over a period of ten months directly from construction jobsites. For further insight on the impact of these factors on productivity, a set of neural network models were developed. Productivity is expressed as a function of one parameter at a time. The trends obtained in this study are compared with related material in literature and the findings are reported.