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The 2002 Nobel Prize in Physiology or Medicine was awarded to
Sydney Brenner (United Kingdom), H. Robert Horvitz (US) and John E.
Sulston (UK) "for their discoveries concerning genetic regulation
of organ development and programmed cell death." Cell death is a
fundamental aspect of embryonic development, normal cellular
turnover and maintenance of homeostasis (maintaining a stable,
constant environment) on the one hand, and aging and disease on the
other. This volume addresses the significant advances with the
techniques that are being used to analyze cell death.
One of the major goals of researchers in the field of apoptosis is
to identify targets for novel therapies in cancer, AIDS, and
Alzheimer s disease. Understanding the molecular mechanisms of the
various components of the apoptotic pathways is the first step to
reaching this goal.
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