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This unique book covers the latest developments in coupling and
decoupling of biomolecules containing functionalized carbohydrate
components, being one of the first collections in this important
area of applied medicinal chemistry. Connecting molecules, often
referred as bio-conjugation, has become one of the most often
performed procedures in modern medicinal chemistry. Sometimes, when
the connected molecules are not useful anymore, they must be
disconnected. The molecules that must be connected (coupled) may
belong to both small and large molecules and include such
constructs as glycoproteins, glycopeptides and glycans. In this
work, more than 15 experts address a comprehensive range of
potential and current uses of in vitro and in vivo bio-conjugation
methodologies, leading to a variety of glycoconjugates. The
analytical aspects of bio-conjugation are also here discussed.
Medicinal and organic chemists from graduate level onwards will
understand the appeal of this important book.
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