While numerous advanced statistical approaches have recently been developed for quantitative trait loci (QTL) mapping, the methods are scattered throughout the literature. Statistical Methods for QTL Mapping brings together many recent statistical techniques that address the data complexity of QTL mapping.

After introducing basic genetics topics and statistical principles, the author discusses the principles of quantitative genetics, general statistical issues of QTL mapping, commonly used one-dimensional QTL mapping approaches, and multiple interval mapping methods. He then explains how to use a feature selection approach to tackle a QTL mapping problem with dense markers. The book also provides comprehensive coverage of Bayesian models and MCMC algorithms and describes methods for multi-trait QTL mapping and eQTL mapping, including meta-trait methods and multivariate sequential procedures.

This book emphasizes the modern statistical methodology for QTL mapping as well as the statistical issues that arise during this process. It gives the necessary biological background for statisticians without training in genetics and, likewise, covers statistical thinking and principles for geneticists. Written primarily for geneticists and statisticians specializing in QTL mapping, the book can also be used as a supplement in graduate courses or for self-study by PhD students working on QTL mapping projects.

This is the first book on the concept and applications of ranked set sampling. It provides a comprehensive review of the literature, and it includes many new results and novel applications. Scientists and researchers on this subject will find a balanced presentation of theory and applications. The mathematical rigor of the theoretical foundations makes it beneficial to researchers. The detailed description of various methods illustrated by real or simulated data makes it useful for scientists and practitioners in application areas such as agriculture, forestry, sociology, ecological and environmental science, and medical studies. It can serve as a reference book and as a textbook for a short course at the graduate level. Zehua Chen is Associate Professor of Statistics at the National University of Singapore. Zhidong Bai is Professor of Statistics at the National University of Singapore; he is a Fellow of the Institute of Mathematical Statistics. Bimal Sinha is the Presidential Research Professor at University of Maryland Baltimore County; he is a Fellow of the Institute of Mathematical Statistics and the American Statistical Association.