This book presents a road map for applying the stages in conceptualization, evaluation, and testing of biomedical devices in a systematic order of approach, leading to solutions for medical problems within a well-deserved safety limit. The issues discussed will pave the way for understanding the preliminary concepts used in modern biomedical device engineering, which include medical imaging, computational fluid dynamics, finite element analysis, particle image velocimetry, and rapid prototyping. This book would undoubtedly be of use to biomedical engineers, medical doctors, radiologists, and any other professionals related to the research and development of devices for health care.

This book provides a comprehensive overview of the author's work which includes significant developments of coronary CT angiography in the diagnosis of coronary plaques. The main contributions of the book lie in the following areas: both 2D and 3D analysis of coronary plaques with coronary CT angiography, diagnostic value of coronary CT angiography with use of different multislice CT scanners, quantitative analysis of coronary plaques in terms of lumen assessment, and bifurcation angle analysis, in particular, the diagnostic performance of coronary CT angiography in calcified plaques, and finally, hemodynamic analysis of plaques with regard to the effects of plaques on coronary blood flow, and CT-derived fractional flow reserve (FFRCT).

Medical imaging of cardiovascular disease has improved rapidly with faster multislice CT angiography. The ability to visualise 3D reconstructed vascular structures has given clinicians a much better appreciation of the anatomy and the disease process. This book provides an overview of the diagnostic applications of CT virtual intravascular endoscopy (VIE) in cardiovascular disease. It is intended to fill the gap by providing a systematic overview of the diagnostic applications of VIE in cardiovascular disease. This book serves as a comprehensive piece of literature that encompasses all aspects from the technical principles of VIE image generation to diagnostic value and potential pitfalls of VIE in cardiovascular imaging. The primary motion to write this book is to provide an overview of the CT VIE in cardiovascular disease with a focus on the clinical applications and diagnostic value of this unique visualisation tool. It is expected that readers, especially clinicians will gain a good understanding of the diagnostic value of CT VIE in the diagnosis of cardiovascular disease, so that their medical practice is enhanced with use of this exciting complementary visualisation tool.