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In a single volume, Monosaccharide Sugars critically summarizes the
applied and potentially useful strategies for the synthesis and
degradation of monosaccharides by chain-elongation, degradation,
and epimerization. These methodologies permit the synthesis of rare
or unnatural monosaccharides that are frequently employed as chiral
building blocks in natural products synthesis, as well as for
producing sugar derivatives labeled with radioactive isotopes.
Representative and well-established experimental procedures are
provided to illustrate the potential of the synthetic
transformation.Degradation of carbohydrates also represents an
invaluable tool for the structural elucidation of certain natural
products, suchas glycosides, antibiotics, and polysaccharides. When
describing the individual methods, unique supplementary collections
of the prepared sugar derivatives are shown in tabular form. This
compendium will eliminate tedious literature searches for those
engaged in research and teaching on the chemistry and biochemistry
of saccharides and other natural products, and also for those
working on the medicinal and metabolic investigation of related
substances of biological importance.
Key Features
* Illustrates the practical potential of well-established
experimental procedures in synthetic transformations
* Provides supplementary collections of prepared sugar derivatives
in tabular form
* Summarizes in a single volume the methods of obtaining
carbohydrate-derived compounds
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