Internationally-recognized pain expert Don Goldenberg helps readers better understand the intricacies of chronic pain through the lens of personal stories, including his own. One out of three Americans lives with chronic pain. Pain is the number one reason we seek medical care and accounts for 40% of doctor visits. Chronic pain is the most common cause of work loss world-wide. The yearly cost of chronic pain in the United States is between $560-$630 billion, higher than that of heart disease, diabetes and cancer combined. Despite this, physicians and the public are woefully ill-informed about chronic pain. The litany of self-help books available to the public are largely misleading, quick-fix, junk-science. Although there is a major push to better inform primary health-care providers on chronic pain, they have been provided no authoritative treatment of the subject. The Pain Epidemic provides the latest medical information and pathways to better understanding and treatment of chronic pain. Dr. Don Goldenberg, an internationally known expert on pain, here discusses such hot topics as the opioid epidemic, mind/body interactions in chronic pain, and gender bias, as well as the role of cannabis and new potential pain treatment. Interested readers will come away with not only a better understanding of the pain epidemic but of pain itself.

This issue of Anesthesiology Clinics, guest edited by Drs. Alison Perate and Vanessa Olbrecht, focuses on Pediatric Anesthesia. This is one of four issues each year selected by the series consulting editor, Dr. Lee Fleisher. Articles in this issue include, but are not limited to: The Pediatric Difficult Airway: Updates and Innovations; Current Knowledge of the Impact of Anesthetics on the Developing Brain; Anesthesia for Innovative Pediatric Surgical Procedures; Pediatric Mass Casualty Preparedness; The Pediatric Burn: Current Trends and Future Directions; Managing the Child with Complex Congenital Heart Disease; Modernizing Education of the Pediatric Anesthesiologist; Regional Anesthesia: Options for the Pediatric Patient; Managing the Pediatric Patient for Anesthesia Outside of the OR; New Trends in Fetal Anesthesia; Anesthetic Implications of the Common Congenital Anomalies; Managing the Adult Patient with Congenital Disease; Trends in Pain Management: Thinking Beyond Opioids; Sustainability in the OR: Reducing Our Impact on the Planet; Current Trends in OSA; and Processed EEG Guided Propofol Infusion in Children.

This issue of Anesthesiology Clinics, guest edited by Drs. Katherine Forkin, Lauren Dunn, and Edward Nemergut, is focused on Gender, Racial, and Socioeconomic Issues in Perioperative Medicine. Topics include: Addressing Racial and Gender Disparities amongst Physicians and the Impact on the Community they Serve; Addressing Racial and Gender Disparities in Critical Care; Care and Outcomes of Religious Minority Patients in the ICU; Genetics and Gender in Acute Pain and Perioperative Analgesia; Women and Underrepresented Minorities in Academic Anesthesiology; Special Considerations Related to Race, Sex, Gender, and Socioeconomic Status in the Preoperative Evaluation; Racial Differences in Cesarean Section and Labor Analgesia; Gender Differences in Postoperative Outcomes after Cardiac Surgery; Perioperative Considerations Regarding Sex in Solid Organ Transplantation; Considerations for Transgender Patients Perioperatively; Health Disparities in Pediatric Anesthesia; Role of Gender and Race in Patient Reported Outcomes and Satisfaction; and Effects of Gender and Race/Ethnicity in Perioperative Team Performance.

There are numerous types of headaches, each with a unique cause, pain profile, and set of treatment options. This book offers readers a broad introduction to this common, yet often misunderstood, group of conditions. What exactly is going on in your body during a headache? How can they be prevented or managed? How can you tell if your splitting headache is actually a brain tumor? This book provides the answers to these and many other questions. What You Need to Know about Headaches is the latest volume in Greenwood's Inside Diseases and Disorders series. This series profiles a variety of physical and psychological conditions, distilling and consolidating vast collections of scientific knowledge into concise, readable volumes. A list of "top 10" essential questions begins each book, providing quick-access answers to readers' most pressing concerns. The text follows a standardized, easy-to-navigate structure, with each chapter exploring a particular facet of the topic. In addition to covering such basics as causes, signs and symptoms, diagnosis, and treatment options, books in this series delve into issues that are less commonly addressed but still critically important, such as effects on loved ones and caregivers. Case illustrations highlight key themes discussed in the book and are accompanied by insightful analyses and recommendations. A holistic approach to the subject covers such often-overlooked areas as societal perceptions and impact on family and friends An Essential Questions section provides quick answers to the questions readers are most likely to have and serves as a springboard to explore the content of the book in more detail Case Illustrations provide relatable, real-world examples of concepts discussed in the text An annotated Directory of Resources points readers toward useful books, organizations, and websites, acting as a gateway to further study and research

Most of the developments in perioperative medicine the 20th century were focused on the establishment of standard monitors, biomarkers, and outcomes measures for the cardiovascular and respiratory systems, with marked improvements in perioperative safety. The fields of anesthesiology and perioperative medicine have now shifted to the consideration of the nervous system. Complications such as delirium, cognitive decline, anesthetic neurotoxicity, stroke and other devastating nervous system events are only now developing significant scientific and clinical attention. Yet there has been no single reference to serve as a guide for the clinician or the investigator in this area. Neurologic Outcomes of Surgery and Anesthesia fills this gap in perioperative medicine literature and provides a concise yet thorough overview of adverse outcomes involving the brain, spine, and peripheral nerves. Rather than being organized by type of operation, each chapter in this invaluable resource is devoted to a specific adverse outcome. Every outcome is reviewed in an easy-to-follow format that includes an introduction to the clinical problem, a section on incidence, prevalence, and outcomes, an assessment of risk factors, discussions of preventive strategies, treatment, and current recommendations, a conclusion, and references.

This issue of Anesthesiology Clinics, edited by Dr. Karsten Bartels and Dr. Stefan Dieleman in collaboration with Consulting Editor Dr. Lee Fleisher, focuses on Cardiothoracic Anesthesia and Critical Care. Topics in this issue include: Anesthetic Management for Endovascular Repair of the Thoracic Aorta; Ethical Considerations for Mechanical Support; Modulating Perioperative Ventricular Excitability; Echocardiography Education for Anesthesia Trainees; Mitochondrial Dysfunction After Cardiac Surgery; New Approaches to Perioperative Right Ventricular Assessment; New Techniques for Optimization of Donor Lungs/Hearts; Recent Developments in Catheter-Based Cardiac Procedures; Heart Failure in Adults with Congential Heart Disease; Optimizing Perioperative Blood and Coagulation Management During Cardiac Surgery; Advances in the Prevention of AKI Following Cardiac Surgery; Clinical Trials That Should be Done in Cardiac Anesthesia; and Cardiac Surgery and the Blood-Brain Barrier.

In collaboration with Consulting Editor, Dr. Lucky Jain, Drs. Hamrick and Ing have put together a comprehensive issue that provides current information of anesthesia, sedation, and pain control in the NICU and for mothers. Clinical review articles are devoted to the following topics: Anesthesia neurotoxicity in the developing brain: Basic studies; Anesthesia neurotoxicity: Update on clinical studies; Neurologic Injury after neonatal cardiac surgery; Effect of repetitive pain on developing brain and physiology of nociception; Sedation/pain control in the NICU; Assessment of Pain in the Newborn; Non-pharmacologic Approaches to Pain Management; Epidurals/spinals for newborn surgery; Neonatal airway management; Effects of maternal anesthesia on perinatal hemodynamics and neonatal acidemia; Maternal anesthesia for urgent c-section; Fetal anesthesia; Neonatal abstinence syndrome (Neonatal Opioid Withdrawal Syndrome); and Opioid crisis in the US: Maternal management. Readers will come away with the information they need to provide better care to the neonate and mothers and improve outcomes.

This accessibly written book examines the most commonly used substances and techniques for managing pain, exploring why they work (or don't), their risks and benefits, and key research findings regarding their use. No one is a stranger to pain. From sudden injuries to post-operative discomfort to nagging aches and stiffness, pain is an unwelcome but familiar part of life. There are numerous methods for managing pain, but it can be difficult to know which is the best fit and to separate truth from hype. Pain Management: Fact versus Fiction examines 30 well-known options for combating pain, whether acute or chronic. Utilizing a standardized structure, each entry discusses a particular substance or technique's origins and underlying principles, how and in what context it's used, and its advantages and disadvantages. Summaries of key research studies are included to help readers better determine which treatments may be a good choice for them. Introductory materials give readers a foundational understanding of what pain is, how it's categorized and measured, and the impact it can have on individuals' physical and psychological well-being. A Further Reading section at the end of each entry points readers toward additional resources to expand and deepen their knowledge. Provides unbiased, evidence-based information to help readers make better decisions about how to manage their pain Summarizes and contextualizes key research findings in easy-to-understand language Utilizes a standardized structure to make it easy for readers to find the exact information they're looking for Covers allopathic therapies as well as complementary and alternative treatments

This book offers an in indictment of the nation's drug enforcement approach focusing on the short-sighted policies that often deny patients suffering from chronic pain the medications they need. Pain Control and Drug Policy: A Time for Change focuses on America's national crisis in pain management caused by the widening divergence between the enormous contributions of opioids ("narcotics") to pain management in the clinical setting and the mistaken belief that they are dangerous, highly addictive drugs. After dissecting the strategy and tactics of the War on Drugs from medical, historical, legal, socioeconomic, and geopolitical perspectives, Guy Faguet MD indicts the 40-year-long War on Drugs for having failed to stem the supply of illicit drugs in America despite expenditures of half a trillion dollars, despite violating the basic human right to pain relief of tens of millions of American chronic pain sufferers, and despite fomenting organized crime, government corruption, racial injustice, and social disruption in both the United States and the producer countries. He concludes with a clarion call for the abandonment of the War on Drugs, disbanding the Drug Enforcement Administration, and encouraging Congress to repeal the Controlled Substances Act. As a clinical and research oncologist responsible for the chronic pain management of thousands of cancer patients over the course of his 30-year career, Dr. Faguet knows that the most effective and safest way to manage most cases of chronic pain is with opioids. All modern pain-management textbooks advocate "titration to effect" in cases where opioids help: that is, gradually increasing the dosage until either the pain is acceptably controlled or the side effects begin to outweigh the pain-relief benefits. Yet the vast majority of doctors don't practice what the medical textbooks teach and instead prescribe opioids very reluctantly and conservatively. As a result, only half of all chronic pain sufferers-and fewer than half of all cancer patients-get adequate pain relief from their doctors. Why do physicians radically undertreat pain that is susceptible to opioid analgesics? They fear that if they prescribe Schedule II opioids in accordance with the professional standards of pain management set by such medical bodies as the American Pain Society, they will be investigated by the DEA, stigmatized, prosecuted as criminals, stripped of their licenses, and sent to jail. Visit Guy B. Faguet, MD's website here: www.faguet.net.

This issue of Anesthesiology Clinics, edited by Dr. Michael T. Walsh in collaboration with Consulting Editor Lee Fleisher, is focused on Ambulatory Anesthesia. Topics in this issue include: Preoperative evaluation for ambulatory anesthesia; Obesity and obstructive sleep apnea in the ambulatory patient; Pediatric ambulatory anesthesia challenges; Safety in dental anesthesia for office-based practitioners; Office-based anesthesia; Regional anesthesia for the ambulatory anesthesiologist; Anesthesia for same-day total joint; Enhanced recovery in outpatient surgery; Outcomes in ambulatory anesthesia: Measuring what matters; ASC Medical director issues; NORA: Anesthesia in the GI suite; MACRA/MIPS/APM, etc: Payment issues in ambulatory anesthesia; Emergency response in the ASC; and Quality Improvement in ambulatory anesthesia.

The incidence of neuropathic pain continues to rise, yet it is an affliction often misdiagnosed or inadequately treated. Although in recent years considerable research has been dedicated to understanding its mechanisms, there have been few advances in treatment. The contributors to this book are internationally renowned leaders in the fields of peripheral neuropathy and neuropathic pain. They discuss clinical approaches to diagnosis and treatment of neuropathic pain, its underlying mechanisms, and strategies for prevention. In addition, chapters cover timely issues, including legal and ethical concerns surrounding pain treatment, the status of clinical trial methods, and educational efforts. Comprehensive yet concise, this book serves as a guide for diagnostic approaches and treatment of neuropathic pain for the student, resident, practicing physician, researcher, and specialist.

This issue of Anesthesiology Clinics, edited by Drs. Maureen McCunn, Mohammed Iqbal Ahmed, and Catherine M. Kuza is dedicated to Cutting-Edge Trauma and Emergency Care. Topics in this issue include: Recognizing preventable death: the role of survival prediction algorithms; ATLS (R) Update 2019: Adult management and applications to pediatric trauma care; Induction agents in specific trauma situations: RSI versus 'slow sequence intubation': Considerations for cervical spine, massive facial trauma, and tracheal disruption; Hemorrhage control and the anesthesiologist: resuscitative endovascular occlusion (REBOA) and emergency perfusion resuscitation (EPR); TEG/ROTEM as a guide for massive transfusion of patients with life-threatening hemorrhage; The anesthesiologist's response to a multiple casualty-incident: our roles working through Hurricanes Irma and Harvey; When the provider becomes the victim: how to prepare for an active shooter in the trauma center; Non-accidental pediatric injuries, pediatric TBI, and sports concussions; Gender disparities in trauma care: how sex determines treatment, behavior, and the outcome; Pain management in trauma in the age of the opioid crisis; The use of point of care ultrasound (PoCUS) in trauma anesthesia care; Post-intensive care syndrome (PICS) and posttraumatic stress disorder (PTSD) in trauma patients; Enhanced recovery after surgery: Are ERAS principles applicable to adult and geriatric trauma and acute care surgery?; and Future trends in trauma care: lessons from current research and treatment strategies in the military.

The aim of this book is not only to introduce readers with a broad spectrum of biological actions of the NOP receptor, but also to feature a detailed look at the N/OFQ-NOP receptor system, medicinal chemistry, pharmacology, and clinical data of NOP-targeted ligands. This special volume book - for the first time focusing on the NOP receptor - is designed to serve as a useful reference, stimulate more research on the N/OFQ-NOP receptor system, and lead to more development of NOP-related ligands for several therapeutic applications.

Advances in Anesthesia highlights the year's significant medical advances, providing one source to review the essential information updates for the Anesthesiologist in that year. The distinguished editorial board, led by Dr. Thomas McLoughlin, includes Drs. Richard Dutton, Laurence Torsher, and Francis Salinas. The board has assembled a first-rate volume for 2018, with topics including care of the severely injured orthopedic patient, patient satisfaction, emergency preparedness and mass casualty considerations, anticoagulant reversal agents, perioperative blood pressure management, postoperative management of nausea and vomiting, anesthesia for noncardiac surgery in patients with implanted LVAD, neurocognitive impact of anesthesia in children, modalities and techniques for labor epidural analgesia and anesthesia, PECS and Serratus Plane Blocks, Transversus Abdominus Plane (TAP) Blocks, cardiac dysrhythmias, right heart failure and pulmonary hypertension, and risks of "non-rate based harms."

Yes, today she feeds the goose that lays the golden eggs But her life once read like a mystery, because for forty-five years she had spasms of the face and neck, her head would ring and, most baffling of all, she had an ache deep in her chest like she was having a heart attack. Unbeknownst to her family, she lived with depression from the age of ten, until finally ending up in a psychiatrist's little crash pad shortly after having a beautiful little girl. From here she began a quest to try to do herself in-she tried six times Then it finally became apparent she was living with chronic pain, and a sublime head injury that kept her from accomplishing her quest of a nursing career. Then, in 2002, at the age of fifty-four, she finally threw up her arms and became willing to do whatever it took to get her life back. She began the twelve-step process of recovery that would open her life to healing. She soon found herself, strangely, thanking God for her affliction. Then, one day in June of 2002, she decided to live. Today she still has the pain but no longer suffers. Now it is a blessing to have lived, because her life has become part of one very big, ongoing miracle, a miracle of which you, the reader, are a part.

This book critiques the current approach to the self-management of persistent pain. The drive towards self-management of chronic pain is flourishing as healthcare systems struggle to facilitate the care of those with long term health conditions. In this book Karen Rodham argues that albeit an empowering idea, self-management has not yet been fully translated from idea to practice and as such, runs the risk of blaming and shaming the person living with a chronic condition for failing to manage their condition effectively. She contends that the additional stress of this tension may in fact worsen their condition. Drawing from the research evidence as well as her practice experience, she advocates a move away from the terms 'self' and 'management' towards a more collaborative approach. One which takes account of the life-context of the person who is living with persistent pain. This book explores the shortcomings of the tendency to focus on self-management without taking into account life context and considers how we got here and what can be done. It will be a valuable resource to researchers and practitioners, especially in the field of health psychology.

Epigenetics of Chronic Pain, Volume Nine, presents comprehensive information on the role of epigenetics in chronic pain sensitivity, providing a detailed, but accessible, view of the field from basic principles, to clinical application. Leading international researchers discuss essential mechanisms of chronic pain epigenetics, including the molecular processes of chromatin remodeling, histone modifications, and the microRNAs and noncoding RNAs involved in regulating genes tied to pain sensitivity. The influence of epigenetics in inflammatory, neuropathic, visceral and other pain models is examined, with data derived from epigenetic studies on peripheral and central mechanisms of pain sensitivity in animal models and clinical cases studies. The studies and case examples cited highlight therapeutic pathways of significance and next steps for researchers to develop epigenetic-based treatments for chronic pain. In recent years, epigenetic regulation of gene expression has been shown to play a central role in managing human pain sensitivity. Findings show that expression of many genes critical to increases or decreases in pain sensitivity are indeed regulated by DNA methylation and its enzymes, histone-involved chromatin remodeling, and noncoding RNAs, mainly microRNAs.

This book describes in fascinating detail the history of the use of anesthesia in childbirth and in so doing offers a unique perspective on the interaction between medical science and social values. Dr. Donald Caton traces the responses of physicians and their patients to the pain of childbirth from the popularization of anesthesia to the natural childbirth movement and beyond. He finds that physicians discovered what could be done to manage pain, and patients decided what would be done. Dr. Caton discusses how nineteenth-century physicians began to think and act like scientists; how people learned to reject the belief that pain and suffering are inevitable components of life; and how a later generation came to think that pain may have important functions for the individual and society. Finally he shows the extent to which cultural and social values have influenced "scientific" medical decisions.

A practical and empathetic guide to a revolutionary approach to living well with chronic pain, based on the fundamental principles that: all pain experienced is real; wherever the trouble originates in the body, pain is experienced in the brain; all pain is unique to the individual sufferer; the key to overcoming pain is not to strive to be pain-free but to minimise the experience of it. Dr Miranda, based on her medical practice as a pain specialist and on her experience as a pain patient, shows how to do this through a series of clearly explained tools and strategies.

This issue of Anesthesiology Clinics focuses on Practice Management, with topics including: Measuring Clinical Productivity; OR Throughput and Efficiency; Measuring Quality of Individual Anesthesia Clinicians; Challenges in outcome reporting; Reporting Quality; Quality and The Health System; Value Proposition and Anesthesiology; Bundled Payments and the Hidden Costs; Pre-Anesthesia Assessment and Pre-Facilitation Process; Perioperative Surgical Home and the Role of Pain Medicine; Anesthesiology's future with Population Health; Successful Negotiations; and Challenges of merging academic and private-practice cultures.