This book explores pain in a number of ways. At the heart of the book is an extension of Melzack's neuromatrix theory of pain into the social, cultural, and economic fields. Specific assemblages involving varied institutions, flows of capital, encounters, and social and economic structures provide a framework for the formation of pain, its perception, experience, meaning, and cultural production. Complementing the extended neuromatrix is a second theory, focussed on the propensity of western market capitalism to seek out new areas of life to subsume to capital. Pain is one such life area that is now ripe for exploitation. Although the book has theory at its heart, it draws extensively on case studies to identify the contradictions and complexities. Case studies are drawn from accounts of drug use in varied contexts such as prescription drugs, methamphetamine use, oxycodone use in North America, and the global rise of the medicinal cannabis marketplace.

This issue brings the anesthesiologist up to date on current essential topics in anesthesia for otolaryngologic surgery, covering the newest cutting-edge procedures.? Topics covered include functional vocal cord surgery; functional endoscopic sinus surgery & skull base surgery; pediatric and adult laryngeal/tracheal surgery; jet ventilation; middle ear; neuromonitoring; transoral robotic surgery; lasur surgery and fire hazards in ENT; office-based procedures; applications of ultrasound in ENT (nerve blocks & airway assessment); LMAs for surgery procedures in head and neck; and anesthesia, OSA, and upper airway collapsibility.

This issue brings the anesthesiologist up to date on current essential topics in ambulatory anesthesia.? Topics covered include obstructive sleep apnea, pediatric ambulatory anesthesia, supraglottic airway devices, issues in office-based ambulatory anesthesia, complex sedation, the role of regional anesthesia in the ambulatory environment, regional catheters, postoperative pain management for the ambulatory patient, and updates on PONV and PDNV.? Authors also explore the questions of how much testing should be done, how to make yourself ASC desirable to patients and surgeons, and more.

'The Year Book of Anesthesiology and Pain Management 2010' brings you abstracts of the articles that reported the year's breakthrough developments in anesthesiology, carefully selected from journals worldwide.

One of the anesthesiologist's greatest challenges is managing high-risk patients with acute or severe conditions.? This issue brings the anesthesiologist up to date on the most important and latest approaches to management of the sickest of patients.? Topics covered include managing the patient with sepsis or septic shock; anesthetic considerations for patients in respiratory failure; anesthetic concerns in patients presenting with renal failure; perioperative management of patients with liver failure; management of acute coronary syndrome in the OR; intraoperative concerns in patients presenting with sever aortic stenosis, aortic insufficiency, mitral regurgitation, or mitral stenosis; intraoperative management of patients with cardiac tamponade; anesthetic concerns in trauma victims requiring operative intervention; patients presenting with acute toxin indigestion; anesthetic concerns in patients with known neurologic insufficiency; management of endocrine insufficiency in the OR; and management of patients with mediastinal mass or tracheal stenosis.

1 Methoden.- 1.1 Elektroenzephalographie (EEG).- 1.1.1 Einfuhrung.- 1.1.2 Entstehungsmechanismen des EEG.- 1.1.3 Methodik der EEG-Ableitung.- 1.1.4 Das normale EEG.- 1.1.5 Pathologische EEG-Veranderungen.- 1.1.6 Diagnostisch relevante EEG-Befunde.- 1.1.7 EEG-Indikationen im Intensivbereich.- 1.2 Ultraschalldiagnostik.- 1.2.1 Physikalische und apparative Voraussetzungen.- 1.2.2 Anatomische und physiologische Voraussetzungen.- 1.2.3 Untersuchungsgang.- 1.2.4 Indikationen der Ultraschalldiagnostik in der Intensivmedizin.- 1.3 Somatosensibel evozierte Potentiale (SEP).- 1.3.1 Einfuhrung.- 1.3.2 Methodik.- 1.3.3 Ursprungsorte der SEP-Komponenten.- 1.3.4 Auswertung und Normwerte.- 1.3.5 Ausfallsmuster bei typischen Schadigungsorten.- 1.3.6 Indikationen zur Ableitung von SEP.- 1.4 Fruhe akustisch evozierte Potentiale (FAEP).- 1.4.1 Einfuhrung.- 1.4.2 Methodik.- 1.4.3 Generatoren des FAEP.- 1.4.4 Auswertung und Normwerte.- 1.4.5 Lokalisationsdiagnostische Bedeutung der FAEP.- 1.4.6 Indikationen zur Ableitung von FAEP.- 1.5 Motorisch evozierte Potentiale (MEP).- 1.5.1 Einfuhrung.- 1.5.2 Wirkungsweise der Magnetstimulation.- 1.5.3 Methodik.- 1.5.4 Auswertung.- 1.5.5 Kontraindikationen.- 1.5.6 Besonderheiten der MEP-Untersuchung auf der Intensivstation.- 1.5.7 Einsatz der MEP auf der neurologischen Intensivstation und im Neuromonitoring.- 1.6 Visuell evozierte Potentiale (VEP).- 1.6.1 Einfuhrung.- 1.6.2 Anatomische und physiologische Grundlagen.- 1.6.3 Technische Durchfuhrung.- 1.6.4 Auswertung.- 1.6.5 Beeinflussung der VEP.- 1.6.6 Indikationen fur VEP-Ableitung in der Intensivmedizin.- 1.7 Elektromyographie (EMG) und Neurographie.- 1.7.1 Einfuhrung.- 1.7.2 Elektromyographie.- 1.7.3 Motorische Neurographie.- 1.7.4 Sensible Neurographie.- 1.7.5 Prufung der neuromuskularen UEberleitung.- 1.7.6 F-Antworten.- 1.7.7 Reflexmessungen.- 1.8 Untersuchung des autonomen Nervensystems.- 1.8.1 Anatomie.- 1.8.2 Physiologie.- 1.8.3 Methodik: Grundlagen.- 1.8.4 Pathophysiologie.- 1.8.5 Methodik: Analyse der Herzfrequenzvariabilitat.- 1.8.6 Allgemeine Befunde.- 1.8.7 Blutdruckmonitoring.- 1.8.8 Methodik: Sympathische Hautreaktion.- 1.9 Exogene und endogene Einflusse auf neurophysiologische Parameter.- 1.9.1 Einfuhrung.- 1.9.2 Exogene Einflusse.- 1.9.3 Endogene Einflusse.- 2 Neuromonitoring bei Intensivtherapiepflichtigen Erkrankungen.- 2.1 Schadel-Hirn-Trauma.- 2.1.1 Einfuhrung.- 2.1.2 Pathophysiologie.- 2.1.3 Klinische Diagnostik.- 2.1.4 Radiologische Diagnostik.- 2.1.5 Neurophysiologische Diagnostik.- 2.2 Hypoxisch-ischamische Hirnschadigung.- 2.2.1 Einfuhrung.- 2.2.2 Ursachen und Pathophysiologie.- 2.2.3 Klinisches Erscheinungsbild.- 2.2.4 Prognose aufgrund der klinischen Untersuchung.- 2.2.5 Bedeutung neurophysiologischer Methoden fur Diagnostik, Verlauf und Prognose.- 2.2.6 Andere Untersuchungen.- 2.3 Intrakranielle Blutungen.- 2.3.1 Einfuhrung.- 2.3.2 Infratentorielle intrazerebrale Blutungen.- 2.3.3 Supratentorielle intrazerebrale Blutungen.- 2.3.4 Subarachnoidalblutungen.- 2.4 Hirninfarkt.- 2.4.1 Einfuhrung.- 2.4.2 Klinische und radiologische Klassifikation der Hirninfarkte.- 2.4.3 Ultraschalldiagnostik.- 2.4.4 Elektroenzephalographie (EEG).- 2.4.5 Fruhe akustisch evozierte Potentiale (FAEP).- 2.4.6 Motorisch evozierte Potentiale (MEP).- 2.4.7 Somatosensibel evozierte Potentiale (SEP).- 2.5 Meningoenzephalitis.- 2.5.1 Einfuhrung.- 2.5.2 Bedeutung neurophysiologischer Methoden fur Verlauf und Prognose.- 2.6 Metabolische und septische Enzephalopathien.- 2.6.1 Einfuhrung.- 2.6.2 Hepatische Enzephalopathie.- 2.6.3 Uramische Enzephalopathie und Dysequilibrium-Syndrom.- 2.6.4 Hypoglykamie.- 2.6.5 Hyperglykamie und hyperosmolares Koma.- 2.6.6 Elektrolytstoerungen.- 2.6.7 Schilddrusenfunktionsstoerungen.- 2.6.8 Weitere metabolische Enzephalopathien.- 2.6.9 Septische Enzephalopathie.- 2.7 Toxische Enzephalopathien.- 2.7.1 Einfuhrung.- 2.7.2 Intoxikation mit Barbituraten und Benzodiazepinen.- 2.7.3 Intoxikation mit Neurol

Foreword by Walter J. Freeman.

The induction of unconsciousness using anesthetic agents demonstrates that the cerebral cortex can operate in two very different behavioral modes: alert and responsive vs. unaware and quiescent. But the states of wakefulness and sleep are not single-neuron properties---they emerge as bulk properties of cooperating populations of neurons, with the switchover between states being similar to the physical change of phase observed when water freezes or ice melts. Some brain-state transitions, such as sleep cycling, anesthetic induction, epileptic seizure, are obvious and detected readily with a few EEG electrodes; others, such as the emergence of gamma rhythms during cognition, or the ultra-slow BOLD rhythms of relaxed free-association, are much more subtle. The unifying theme of this book is the notion that all of these bulk changes in brain behavior can be treated as phase transitions between distinct brain states.

Modeling Phase Transitions in the Brain contains chapter contributions from leading researchers who apply state-space methods, network models, and biophysically-motivated continuum approaches to investigate a range of neuroscientifically relevant problems that include analysis of nonstationary EEG time-series; network topologies that limit epileptic spreading; saddle--node bifurcations for anesthesia, sleep-cycling, and the wake--sleep switch; prediction of dynamical and noise-induced spatiotemporal instabilities underlying BOLD, alpha-, and gamma-band Hopf oscillations, gap-junction-moderated Turing structures, and Hopf-Turing interactions leading to cortical waves.

Perioperative care is the care that is given before and after surgery. This textbook is a complete guide to the anaesthetic and critical care management of patients undergoing complex surgeries in all organ systems of the body. Topics cover all age groups - neonates, children, and adults. Divided into 11 sections, the book begins with a general overview of critical care in the perioperative period discussing airway management, pain, fluid and electrolyte therapy, shock, arterial blood gas analysis, respiratory failure and mechanical ventilation, and thromboembolism. The following sections cover surgeries in different organ systems and patient groups - cardiothoracic and vascular, neurosciences, paediatrics, obstetrics and gynaecology, gastrointestinal, genitourinary, orthopaedics, head and neck, and transplantation. The final section explains selected miscellaneous topics including nutrition, haemodynamic monitoring, echocardiography, renal replacement therapy, and antibiotics. Compiling 700 pages, the comprehensive text is further enhanced by clinical photographs, diagrams and tables. Key points Comprehensive guide to perioperative critical care in neonates, children and adults Covers complex surgeries in all organ systems Includes discussion on imaging, airway management, and ventilation Highly illustrated with clinical photographs, diagrams and tables

Topics: Perioperative Care of Patient with Chronic Opioid Dependence; Anesthesia for Sites Outside the OR; New Developments in Anesthesia Ventilators and Machines; Future of Clinical Research/Ethics in Human Experimentation; Perioperative Glucose Management; Inflammatory Response to Anesthesia and Ways to Attenuate; Chemical Dependence; Anesthesia for Awake Craniotomies; Hyperthermic Peritoneal Chemotherapy; ACGME Competencies; Renal Function Update; Professionalism; New Developments in Neonatal Resuscitation; Automated Anesthesia

This issue brings together leading specialists from diverse fields including multiple subspecialties of anesthesiology, as well as surgery, cardiology, oncology, neurology, hospital medicine, endocrinology, and others. A multidisciplinary approach is essential to patient safety and optimal outcomes, so this valuable and unique monograph brings the anesthesiologist up to date on current integrated methods of preoperative assessment, consultation, and patient preparation for surgery. Article topics include preoperative evaluation and prep of the patient for cardiac surgery; noncardiac surgery in the patient with heart disease; identification and evaluation of the patient with lung disease; surgery on the patient with endocrine dysfunction; obesity, metabolic syndrome, and the surgical patient; surgery in a patient with liver disease; surgery in the patient with renal dysfunction; anemia in the preoperative patient; perioperative anticoagulant management; preop prep of the surgical patient with neurologic disease; and emergency and urgent surgery.

This issue of Anesthesiology Clinics prepares the anesthesiologist for the most challenging problems he will face with geriatric patients. Topics covered include delirium, postoperative cognitive dysfunction, fat embolism during hip replacement, Parkinson's disease and deep brain stimulator placement, diastolic dysfunction, atrial fibrillation, delayed arousal, severe atrial stenosis, multiple medications, informed consent and the ethical management of the older patient, dead bowel, acute perioperative beta-blockade in the older patient, urinary retention, and anesthetic care for patients with skin breakdown.

This book would combine chapters written by the most qualified authors around the world whose research encompasses the effect of morphine or other opioids on tumor growth and metastasis. This includes clinicians involved in trials determining which type of post surgical pain management can minimize the risk of recurrence or metastasis, researchers working on animal models and studying the effect of morphine on tumors, and most importantly the mechanism for this effect, and lastly cell biologists. There is currently a lot of research going on trying to reconcile the pro- and anti-cancer aspects of opioids actions.

This issue of Anesthesiology Clinics covers the most cutting-edge topics in pediatric anesthesia that every practitioner must know to stay current in this changing field. Topics covered include new devices for difficult pediatric airway, the use of ultrasound in pediatric regional anesthesia, new concepts in treatment of pediatric traumatic brain injury, acute pain management, neurotoxicity of anesthetics in the developing brain, current thought on intraoperative awareness in children, current concepts on managing sepsis in children, the fontan patient, sedating the child with congenital heart disease, management of children with hemoglobinopathies, and current strategies for blood conservation in pediatric anesthesia.

Many of the earliest books, particularly those dating back to the 1900s and before, are now extremely scarce and increasingly expensive. We are republishing these classic works in affordable, high quality, modern editions, using the original text and artwork.

Methadone and buprenorphine are the only two opioids that are indicated for the management of both pain and opioid-related drug addiction. Both present unique challenges to the general practitioner and pain specialist, requiring a separate analysis from the rest of the drugs in the same family. Handbook of Methadone Prescribing and Buprenorphine Therapy is an invaluable guide to the safe use of these opioids. Authored by clinical and academic leaders from a variety of settings and backgrounds, this book includes chapters on pharmacology, adverse effects, safe rotation from other opioids, cardiac toxicity, prescribing, pharmacokinetics, equianalgesic dose and replacement therapy. This comprehensive text provides clinicians, researchers, policy-makers and academicians a resource for all the relevant points in methadone prescribing and buprenorphine therapy.

Hemoglobin-based Oxygen Carriers is an exciting and evolving alternative to blood transfusion. This issue explores its potential with topics on: "HBOCs from Human or Bovine Hemoglobin," "Comparison of HBOCs to Stored Human Red Blood Cells," "HBOCs and Tissue Oxygenation," "HBOCs: Role in surgery, resuscitation or hemorrhagic shock?" and more!

For an anesthesiologist, though the challenge of managing an obstetric patient can be very satisfying and rewarding, it can also be extremely difficult given the potential for serious harm to the fetus and mother. For routine care, it is important to understand the risks and benefits of many practices to provide patients with informed decisions and the most satisfying experiences. There are also many less-usual patients and situations, however, that challenge the anesthesiologist's skills significantly. This issue of the Anesthesiology Clinics presents the most up-to-date information on both of these categories, and is written by an outstanding group of experienced clinicians from all over the world. Topics including high-risk analysis, use of simulators for training, major hemorrhage, off-labor-floor consultation, depth of anesthesia monitoring, pharmaceuticals, use of vasopressors, neurological infections after neuroaxial anesthesia, airway management, the HIV patient, ultrasound, and others.

This text contains the edited presentations of the 39th Annual Postgraduate Course in Anaesthesiology, February 1994. The chapters reflect new data concepts within the general framework of pain research and basic science, and clinical topics in pain management. The purpose of the textbook is to serve as a vehicle to bring many of the latest concepts in anaesthesiology to those who did not attend the conference, within a short time of the formal presentation. Each chapter is a brief by sharply focused glimpse of the current interests in anaesthesia. This volume, as well as past and future volumes, reflects the rapid and continuing evolution of anaesthestiology in the late-20th century.

"Anaesthesia and the Lung 1992" presents recent advances in the diagnosis, pre-, intra-, and postoperative anaesthetic management of patients with lung disease, presenting for pulmonary and non-pulmonary surgery. It also deals with ventilation - perfusion issues, the lung as a metabolic organ, the effects of anaesthesia on pulmonary mechanics and pulmonary blood flow. In addition, there are chapters that focus on hypoxia; regional differences in the lung; pulmonary surfactant; recent advances in the understanding of pulmonary edema; high altitude disease; anaesthesia and the control of breathing; recent development in oximetry; instrumentation designed to measure pulmonary oxygen tension, pO2 and pCO2 transcutaneously; differential lung ventilation; reactive airways; septic shock; the adult respiratory distress syndrome and numerous aspects of ventilatory support.

Pain management is a growing area of interest for many health care professionals. It is a truly integrated approach involving a team comprising medical practitioners, clinical psychologists, physiotherapists, occupational therapists and nurse practitioners. Different professions may work together but the approach may also be adopted by individual practitioners. Pain Management: An Interdisciplinary Approach deals specifically with the management of potentially chronic l pain, how to assess patients with pain, the factors involved in the development of chronic pain and the setting up and running of a pain management programme. The main focus is on musculoskeletal and fibromyalgic type pain. Cancer pain is not addressed. The authors address not only what is recommended in the management of pain but also whether and why it is done, thereby covering not only the content of interdisciplinary pain management but also the processes involved. An increasing number of courses on pain management are now being set up around the world. This has created an increasing and continuous demand for a textbook which could be used by those attending these courses and which would provide others who have to deal with the problems as part of their day to day practice with guide to best practice. The book provides an essential reference for all health professionals involved in all aspects of pain management. Provides extensive background material and covers broad issues which other books lack Focuses on not only what is done with the management of pain but whether and why it is done Includes the nuts and bolts of setting up and running a pain management programme Addresses the application of pain management programmes in a wide range of fields Has a multidisciplinary approach and therefore appeals to a multidisciplinary market Two new co-authors: Kay Greasley and Bengt Sjolund. Major restructuring of chapters and rewriting of content with new authors for many of them. Greatly increased discussion of biopsychosocial management in individual clinical practice. Addresses the needs of the individual practitioners as well as those working in specialised pain management units. Includes more on primary care and secondary pain prevention. Expanded discussion of the clinical-occupational interfaces. Particular emphasis on the identification and targeting of modifiable risk factors for chronic pain and prolonged disability. The following topics stregthened throughout: communication, the nature of groups, medication and iatrogenics. Potential of an evidence-based biopsychosocial approach to pain management highlighted.

This groundbreaking analysis moves our knowledge of pain and its effects from the biomedical model to one accounting for its complex psychosocial dimensions. Starting with its facial and physical display, pain is shown in its manifold social contexts-in the lifespan, in a family unit, expressed by a member of a gender and/or race-and as observed by others. These observations by caregivers and family are shown as vital to the social dynamic of pain-as observers react to sufferers' pain, and as these reactions affect those suffering. The book's findings should enhance practitioners' understanding of pain to develop more effective individualized treatments for clients' pain experience, and inspire researchers as well. Among the topics covered: Why do we care? Evolutionary mechanisms in the social dimension of pain. When, how, and why do we express pain? On the overlap between physical and social pain. Facing others in pain: why context matters. Caregiving impact upon sufferers' cognitive functioning. Targeting individual and interpersonal processes in therapeutic interventions for chronic pain. Social and Interpersonal Dynamics in Pain will be a valuable resource for clinicians who deal in pain practice and management, as well as for students and researchers interested in the social, interpersonal, and emotional variables that contribute to pain, the processes with which pain is associated, and the psychology of pain in general.

Decision making regarding fluid volume loading, fluid restriction, or administration of vasoactive drugs may vary among physicians, depending solely upon their clinical experience in the absence of evidence-based measurement. The initial distribution volume of glucose (IDVG) is believed to be clinically relevant as a marker of cardiovascular and fluid management in critically ill patients without a significant modification of glucose metabolism. This book covers all aspects of IDVG measurement, including the basic concept, its relationship with other fluid volumes, and the clinical application of this technique in the intensive care unit based on both the authors studies and their clinical experience with more than 4000 IDVG determinations. When the concept of IDVG is properly understood and its measurement is then performed routinely, daily fluid and cardiovascular management in critically ill patients can be improved based on evidence-based measurement."