This authoritative Handbook compiles a diverse set of contributions on digital entrepreneurship, providing an in-depth study of how digital entrepreneurship research has evolved over the years, and where it stands today. Offering a snapshot of the major themes in digital entrepreneurship research, the Handbook highlights a wide range of both practice-engaged and practice-relevant works and explores the fundamental concepts and common themes in the field. Chapters examine key topics including the digital platform economy, the digitalization of work, the blockchain economy, and the rural-urban digital divide. The Handbook further analyzes the history and theory of digital entrepreneurship, while also sparking ideas for future research through a consideration of emerging phenomena and new ways to approach research in this broad area of study. Discussing a diverse set of questions, contexts, theories, and methods, this Handbook will be a key resource for researchers and advanced students with a particular interest in entrepreneurship, innovation, technology management, and digital business models. Managers and entrepreneurs will also find the discussion of digital entrepreneurship in relation to financing, social issues, and technology beneficial.