Auf die Bedurfnisse der taglichen Praxis abgestimmt
Strukturierte, klar definierte Vorgehensweisen fur Diagnostik, Therapiekonzepte und personalisierte Therapieziele.

Umfassende Information, inklusive
- Pravention, Fruherkennung
- Begleiterkrankungen: Fettstoffwechselstorungen, Hypertonie ...
- Folgeerkrankungen: Gefasserkrankungen, Nephropathie, Neuropathien ...
- Patientenschulung: Ernahrung, Lebensfuhrung ...
Besonderheiten bei
- Kindern/Jugendlichen, Schwangeren, alten Patienten
- perioperativer Betreuung, enteraler und parenteraler Ernahrung
- psychiatrischen Erkrankungen einschliesslich Demenz
- Sport, Reisen
Komplexe Fragen kompetente Antworten
- Stufentherapie individuell abgestimmt auf Begleiterkrankungen, Bedurfnisse und Moglichkeiten des Patienten
- Praxistipps fur typische und atypische Therapieprobleme
- neue und zukunftige Therapieformen

NEU u.a.
- Bariatrische Chirurgie
- Compliance und Empowerment
- Qualitatssicherung und Versorgungsforschung
- DMPs, DRGs

Nach den Leitlinien/Richtlinien
- Deutsche Diabetes Gesellschaft (DDG)
- Osterreichische Diabetesgesellschaft (ODG)
- Schweizerische Gesellschaft fur Endokrinologie und Diabetologie (SGED)

Interdisziplinar, topaktuell. Von den fuhrenden Experten aus Deutschland, Osterreich, Schweiz.

Wissen fur das optimale Diabetes-Management gerade heute besonders wichtig."

As the incidence of diabetes increases worldwide, the need for recommendations on how to prevent and treat the condition grows exponentially, and so does the need for an authoritative source for information on the appropriate models to study the condition. The new edition of Animal Models of Diabetes is that source. The book presents updated and expanded information regarding the use of models in experiments with both Type 1 and Type 2 diabetes. The new edition compiles relevant time-saving information on well-recognized models, including various mice, rats, minipigs, and Rhesus monkeys, and provides extensive references for more in-depth study. It contains new and updated referenced reviews on animals with induced obesity as well as observations on retinopathy in spontaneous diabetes resembling human lesions. The book discusses nutritionally diabetes-prone animals and considerations of insulin resistance and obesity. The contributors also address the importance of recent findings on the pathogenesis of diabetes and its complications in relation to human disease. Including contributions from prominent experts in the field, the book brings together scattered data and lucidly presents it. This promotes the understanding of the etiopathology of diabetes and offers a new grasp of the insulin action, its negative feedback leading to insulin resistance, and its detrimental outcomes. The book also includes new knowledge on specific complications of diabetes, offering an incentive to test advanced modalities to prevent and inhibit their occurrence.

Vassopressin, Volume 111, the latest release in the Vitamins and Hormones series, first published in 1943, covers the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms, with this release focusing on topics relating to hepcidin, bacterial infection, and iron overload, the role of heparan sulfates in hepcidin regulation, hepcidin CDNA and human gene sex hormones, growth factors and hepcidin, HFE gene polymorphisms and hereditary hemochromatosis, hepcidin and il-1beta, hepcidin-ferroportin axis, cardiomyocyte hepcidin, adipocyte iron, leptin and hepcidin, regulators of hepcidin expression, and much more.

Dealing with Diabetes Burnout: How to Recharge and Get Back on Track When You Feel Frustrated and Overwhelmed Living with Diabetes is an inspiring and empowering guide to managing the daily work and pressure of diabetes management - counting carbohydrates at every meal, constantly adjusting medication doses, taking daily injections, pricking fingers multiple times a day, and struggling with the unavoidable challenges of fancy, yet imperfect, technology - that can lead to burnout. Vieira provides the tools and encouragement needed to help readers get back on track and make diabetes management a rewarding priority. Chapters directly address burnout in relation to: food, exercise, insulin dosing, blood sugar checking, fear of low blood sugar, being a caregiver/spouse of a person with diabetes, communicating more effectively with your doctor, taking a healthy ""vacation"" from diabetes, and creating realistic expectations and goals.

Self-manage digestive disorders through dietary choices

Suffering from a gastrointestinal disorder–whether it’s irritable bowel syndrome, gas, constipation, heartburn, or another condition–can be embarrassing and debilitating. While medical treatments and prescriptions can offer relief, one of the most important ways you can help yourself is to choose the right foods to eat.

Backed by the American Dietetic Association, this user-friendly guide shows you how to analyze your eating habits so that you can map out a dietary plan to manage and reduce the uncomfortable symptoms of digestive disorders. You’ll find practical recommendations for implementing changes in your lifestyle and advice on steering clear of common dietary mistakes. Your meals will be pleasurable and nourishing experiences–not painful ones–when you discover how to make the best and most comfortable food choices so you can embark on the road to digestive health.

The definitive guide to eating well and staying healthy with diabetes

"Nutrition is pivotal to diabetes care. This book is a terrific tool for managing diabetes through good nutrition. It’s a guide you can use every day–a treasure chest of advice on how to eat healthfully."
–Richard M. Bergenstal, MD, Executive Director
International Diabetes Center, Minneapolis, Minnesota

From the American Dietetic Association comes this authoritative guide to choosing foods to control your blood sugar and maintain an active, healthy lifestyle. It provides the must-know basics of daily diabetes care–from designing a food plan and preventing low blood glucose levels to losing weight and carbohydrate counting–so you can personalize diabetes and food decisions to fit your needs. You’ll see how to manage blood fat levels and blood pressure–an important part of diabetes care–and gain invaluable insight into making healthy food choices and planning tasty meals. You’ll also find tips on reducing sugar and fat in foods; quick and easy meal ideas; and a special section on prevention of type 2 diabetes.

• Detailed menu plans for daily caloric levels of 1,200, 1,500, 1,800, 2,000, and 2,500 calories
• Includes fast-food restaurant and ethnic food guides
• Ratings for high, low, and moderate glycemic index foods

A simple new dietary approach to preventing and treating diabetes

You can help prevent and control diabetes through simple diet and lifestyle changes that are a pleasure to make instead of a chore. This book shows you how. Drawing on the latest diabetes research, Healthy Eating for Life to Prevent and Treat Diabetes presents a complete and sensible plant-based nutrition program that can help you prevent, manage, and, in certain cases, even reverse diabetes.

Covering Type 1(childhood-onset), Type 2 (adult-onset), and gestational diabetes, this book provides detailed nutritional guidelines that have been carefully drafted by Physicians Committee diabetes experts, along with nearly 100 delicious, easy-to-make recipes to help you put these healthy eating principles to work right away. Healthy Eating for Life to Prevent and Treat Diabetes contains important information on:

• Exercise and lifestyle issues
• Achieving and maintaining healthy weight
• Diabetes and pregnancy
• Preventing complications from diabetes
• And more

Whether you or a loved one has diabetes or is at risk of developing it, this book will give you the crucial knowledge you need to take charge now–of your diet, your health, and your life.

Also available:

Healthy Eating for Life to Prevent and Treat Cancer (0-471-43597-X)
Healthy Eating for Life for Children (0-471-43621-6)
Healthy Eating for Life for Women (0-471-43596-1)

With the increasing incidence of Type 2 diabetes in the adult population and the realization that this is a vascular disease and a major coronary risk factor, Professor Betteridge has chosen fifty diabetologists to contribute a case which has had an effect on their clinical practice. Both Types 1 and 2 diabetes are included, along with other forms of diabetes, eg gestational. Each case is presented in the same format. The various cases are informative and educational and should provide the reader with a sounder knowledge of patient and disease types.

Prevention and Recovery from Eating Disorders in Type 1 Diabetes: Injecting Hope sheds light on an often overlooked and misunderstood issue: the problem of eating disorders in women with type 1 diabetes - referred to by lay people and the media as "diabulimia" and characterized by insulin restriction as a means of calorie purging for weight loss. Drawing on a series of recent interviews and over 16 years of research and clinical experience with this unique phenomenon, author Dr. Ann Goebel-Fabbri provides groundbreaking insight into the lives of women who have recovered from eating disorders in type 1 diabetes. She explores the condition's origins, its effects on the lives of those affected, and possible paths to recovery. Also included are suggestions for prevention and treatment, as well as practical and inspirational advice from now-recovered women. Prevention and Recovery from Eating Disorders in Type 1 Diabetes is a valuable guide for patients and loved ones, diabetes treatment teams, and eating disorder clinicians.

You can feel great again!

"Syndrome X proactively lays out a nutritious, tasty, and simple diet plan to get us back to the basics of healthy nutrition."–Lendon H. Smith, M.D., New York Times bestselling author of Feed Your Body Right

"Syndrome X is the best new book to help you understand the facts about nutrition, health, and aging. . . . It is full of new information and insights most readers have never had access to before. Everyone who values his or her health will want to read the book and then individualize the program to suit his or her needs–the authors have made this easier than ever to do."–Richard A. Kunin, M.D., author of Mega-Nutrition

What is Syndrome X? It’s a resistance to insulin–the hormone needed to burn food for energy–combined with high cholesterol or triglycerides, high blood pressure, or too much body fat. Syndrome X ages you prematurely and significantly increases your risk of heart disease, hypertension, obesity, eye disease, nervous system disorders, diabetes, Alzheimer’s, cancer, and other age-related diseases.

Syndrome X is the first book to tell you how to fight the epidemic disorder that is derailing the health of nearly a third of North Americans. It outlines a complete three-step program–including easy-to-follow diets, light physical activity, and readily available vitamins and nutritional supplements–that will safeguard you against developing Syndrome X or reverse it if you already have it.

This second edition updates the "WHO Classification of Endocrine Tumours" proposed in 1980 and incorporates many new tumour entities and pertinent concepts that have developed since that time. It is the result of a collaborative effort between 9 pathologists from different countries, in addition to informal contributions and discussions by many other colleagues. In particular, efforts have been made to integrate into the fundamental backbone of the histologic classification a number of prognostic and functional parameters now essential for appropriate diagnosis and clinicopathologic evaluation of endocrine tumours.

The indispensable guide to all aspects of clinical care, the Oxford Handbook of Endocrinology and Diabetes has been fully updated for its fourth edition, providing comprehensive coverage of both disciplines in a practical and concise format. Featuring new chapters on transition in endocrinology and diabetes, practical nursing considerations, and the genetics of endocrinology, and expanded sections on inherited endocrine syndromes and MEN, it retains the clear organisation and layout for ease of reference as the previous edition over a broader range of topics. Combining authority, relevance, and reliability, this title includes new therapies and guidelines alongside 'clinical pearl' and 'tricky situation' boxes to aide readers in rare or complicated situations. This is the must-have guide for all trainees and specialist nurses in endocrinology and diabetes.

The author, blind since 1984 from complications of diabetes, talks about his own experiences.

As an endocrinologist and research scientist--and a diabetic for over 29 years--Dr. Joseph Juliano has devoted his life to understanding the disease. Now, he shows the millions of Type I, insulin-dependent diabetes sufferers how to avoid complications and overcome them if they occur, empowering readers with the motivation and information to control their disease.

Male infertility is a clinician-orientied book aimed at the clinician dealing with the infertile couple because rational, effective management is only possible if the couple are considered together. The aim of the work is to provide advice to the clinician and to give reference to the underlying science. This will not only enable clinicians to understand the underlying science but will also give scientists an insight to clinical work. This blend of science and clinical work is reflected in the contributors who are experts drawn from both fields.

Take control of your weight--and your diabetes. Managing your weight is critical when you have diabetes. In fact, losing as little as 10 to 20 pounds can improve diabetes control. With this innovative book, you can manage your weight and your diabetes by making gradual lifestyle changes you'll be able to live with for the rest of your life--like following a low-fat meal plan, becoming more active, and managing stress. Weight Management for Type II Diabetes will help you assess habits, teach you techniques of behavior change, and motivate you to find the support you need to manage both diabetes and your weight. This interactive guide takes you through the steps of developing a personalized plan that considers your lifestyle, personality, family situation, and wants and needs. Authors Jackie Labat, MS, RD, CDE, and Annette Maggi, MS, RD, will help you:
* Set reasonable goals
* Keep pace with an exercise program
* Design your own meal plan
* Handle special occasions
* Manage stress
* Learn to deal with lapses
The book also provides fat and calorie counts, grocery shopping tips, and a lesson in low-fat cooking.

Peroxisomal disorders constitute a major research front in clinical genetics, paediatrics and cell biology. Since 1983, the metabolic defect in some 20 different peroxisomal disorders has been described. The best known conditions include Zellweger syndrome, rhizomelic chondrodysplasia punctata and X-linked adrenoleukodystrophy and, in the most recent edition of The Metabolic and Molecular Basis Inherited Disease, edited by Scriver and colleagues, more than 100 pages are now devoted to the subject. Progress in our understanding of these conditions, and their diagnosis, results from the application of a variety of laboratory investigations. These include microscopic studies, analysis of metabolites (very long-chain fatty acids, bile acids, and plasmalogens), enzyme studies (peroxisomal beta-oxidation pathway and dihydroxyacetone phosphate acyltransferase), immunodetection of peroxisomal (membrane) proteins and molecular analysis of mutant DNA. In order to encourage a greater awareness in this field and the diagnostic protocols required, an international course was organised in Gent, Belgium, in May 1994, on the clinical and biochemical diagnosis of peroxisomal disorders. A number of international experts in the field who provided intensive hands-on experience over 3.5 days, have now collected their course work and reviews together in this Handbook. The volume is introduced by Sidney Goldfischer, who in 1973 was the first to recognise the absence of peroxisomes in Zellweger syndrome, but whose observations were not fully appreciated for a further decade. This handbook provides the most comprehensive and detailed account of laboratory methods for the diagnosis of peroxisomal disorders. The methods are clearly presented and well illustrated, and should allow laboratories to introduce these methods into their repertoire. Audience: Paediatricians, neurologists, clinical biochemists, pathologists, genetic counsellors, obstetricians, and GPs interested in the recognition, diagnosis and prenatal prevention of peroxisomal disorders.

Cryptorchidism remains a common but poorly understood anomaly affecting 2%-5% of children. Major controversies exist over the timing and type of treat ment (i. e. surgical vs hormonal therapy) and whether intervention prevents sub sequent infertility and testicular cancer. Part of the dilemma is caused by lack of understanding of the normal process of descent, despite intensive research and study since the eighteenth century, when Hunter and von Haller first described the gubernaculum (caudal genito-inguinal ligament) and processus vaginalis (Williams and Hutson 1991a). More needs to be known, not only of the normal mechanism, but also of the ways that it can be deranged to produce undescended testes. This review describes the recent results of studies on normal descent, with emphasis on our studies of the different stages of descent. As the reader will appreciate, the ever-more complex models proposed to account for normal tes ticular descent predict that undescended testes will be caused by a multitude of anomalies affecting different stages of the process. A description is given of current hypotheses of the aetiology of cryptorchidism, correlating these with studies of cryptorchid animal models. For a more detailed description of the numerous ideas about the mechanism, the reader is referred to Heyns and Hutson (1995) and other monographs (Fonkalsrud and Mengel 1981; Abney and Keel 1989)."

This volume focuses on the investigatory methods applied to autosomal dominant polycystic kidney disease (ADPKD), one of the most common human genetic diseases. ADPKD is caused by mutations in PKD1 and TRPP2, two integral membrane proteins that function as receptor/ion channels in primary cilia of tubular epithelial cells. Thus, ADPKD belongs to ciliopathies, a group of disorders caused by abnormal cilia formation or function. This proposed book will cover the state-of-the-art methods ranging from molecular biology, biochemistry, electrophysiology, to tools in model animal studies. Key Features Explores the role of cilia in polycystic kidney disease Focuses on myriad state-of-the-art methods and techniques Reviews specific mutations integral to this autosomal genetic disease Includes discussions of model systems

Diabetes has garnered worldwide attention and research funding as clinicians and researchers seek to better understand its pathogenesis, prevention, complications management, and impact and relationship to other diseases (heart disease, kidney disease, infections, and inflammation). Clinicians are overwhelmed with rapidly evolving developments regarding the science and clinical management of diabetes and are struggling to understand and apply new diabetes information. This book will provide a concise interpretation of translational diabetes research for the purpose of preparing clinicians to understand and effectively deploy new strategies and therapeutics into the clinical care of diabetes patients by examining: the contrast between existing information in the clinical practice versus the basis and need for future clinical trials breakthroughs within clinical trials and methods to incorporate bench to bedside material for the clinical practice the synthesis and interpretation of the scientific principles, trial results, and clinical implications of emerging and translational therapies, and the management strategies for diabetic patients the entire scope of translational diabetes research from biology to screening and prognosis, new therapeutics, insulin, transplantation, and complications management new therapeutic strategies to knowledgeably and effectively equip the practicing clinician assembles information that is scattered throughout the diabetic community into one concise single reference

In September of 2007 Gaucher Disease received a commendation in the Haematology category of the 2007 British Medical Association Medical Book Competition! Although rare in the general population, Gaucher disease is the most prevalent of the lysosomal storage disorders, making research into this particular orphan disorder an invaluable prototype for the diagnosis, research, and treatment of others. Like many rare conditions, Gaucher disease has benefited from the explosion of medical research in the last decade, the amount of new information on this disease is staggering and the rate of new discoveries has left previous books on the subject unable to provide useful, up-to-date information. The most current, fully comprehensive reference to date, Gaucher Disease provides valuable information for academic and industry scientists, and clinicians. Outlining the latest research on the biochemical mechanisms and pathology of lysosomal storage disorders, this book covers diverse topics including animal models, crystallography, imaging and radionuclide evaluation. It not only addresses the developmental basis for current treatments like the now widely available enzyme replacement therapy, but also includes chapters introducing new therapies on the horizon. With contributions from world-renowned experts in substrate reduction therapy, pharmaceutical chaperone therapy, hematopoietic stem cell transplantation and gene therapy, as well as chapters on a second generation of enzyme replacement therapy, this book explores the full spectrum of possibilities offered by the most recent advances in medicine. Some of the most interesting aspects of the book include the discussions on patient management, those touching on the ethics of research, and the societal aspects of treating rare diseases with expensive therapy.

Craniopharyngioma represents a major challenge for neurosurgeons, pediatricians, and endocrinologists. This so-called benign tumor is a real threat to quality of life and life itself. This book discusses the various therapeutic strategies and suggests multimodal treatment approaches, including microsurgery, stereotaxis, and alternative treatments. The rationale for choice of therapy is supported by biological, clinical, and neuroradiological data and therapeutic results of a large series of case studies from all over the world are reported. Finally, guidelines for further development and new topics for research and treatment are offered.