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Endocrinology of Embryo-Endometrium Interactions (Paperback, Softcover reprint of the original 1st ed. 1994)
Loot Price: R1,539
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Endocrinology of Embryo-Endometrium Interactions (Paperback, Softcover reprint of the original 1st ed. 1994)
Series: Reproductive Biology
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Early embryonic loss is a continuing social and economic global
problem. In human populations the estimates of interruptions early
in pregnancy range from 35-60%. In animal husbandry (swine,
ruminants) fully 30% of pregnancies fail to survive early events of
gestation. The futility associated with this persistant high risk
is even more unsettling because of advances made in assisted
reproductive technology which, although this very selective
methodology has added to our knowledge of embryo-endometrial
interactions, has resulted in a birth rate of only 14%. These
studies have instigated comparisons of the live relative
contributions of the embryo and the uterus to the outcome of
pregnancy. These analyses have shown that we have learned
significantly less about the role of the uterus in deciding the
outcome of either natural or assisted pregnancies. In 1979 a
quotation by George Corner was used to set the tone of a meeting
that was devoted to discussion of the cellular and molecular
aspects of implantation. In spite of the proliferation in research
activity which occurred in the following 15 years our real
understanding of the embryo transfer process has fallen short of
our expectations. We use the Corner quotation, once again, to
preface this symposium so that we may recall that the fundamental
nature of the process which regulates embryo-endometrial
interactions still escapes us.
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