The author designed his first shell and tube heat exchanger in 1965 using a slide rule. The book covers the development of calculations methods from then until the present time. It is a technical autobiography which includes personal accounts of interesting developments and challenging designs. The book contains only a basic coverage of heat transfer and pressure drop correlations since these may be found in many other more general books on heat transfer and fluid dynamics. Instead the emphasis is on how to identify key variables and the impact they have on that elusive 'optimum design'. The need to visualise what is taking place in a heat exchanger is an important part of the book and many novel ways of doing this are suggested. The mechanical aspects of shell and tube design are covered in sufficient detail for a thermal design engineer to have confidence that what they are proposing is realistic and can be manufactured. Limitations are discussed where it is advisable to seek specialist advice. The work of the process engineer is also covered in many sections and the need for coordination between process and thermal designers is a feature of the book. There is guidance on how to use modern sophisticated computer design programs and the potential pitfalls they will always contain. There are many examples of complex designs which require 'fudged' computer runs and supplementary hand calculations. There are a number of suggestions as to how some of the current programs may be improved. The SI system of units has been used throughout wherever practical. The main target market is practicing thermal design engineers. The book should also be useful to many other engineers who have to deal with heat exchangers particularly process engineers. The book is suitable for students on first degree and masters degree courses in engineering particularly those studying chemical engineering.

Digital Human Modeling and Medicine: The Digital Twin explores the body of knowledge and state-of-the-art in Digital Human Modeling (DHM) and its applications in medicine. DHM is the science of representing humans with their physical properties, characteristics and behaviors in computerized, virtual models. These models can be used standalone or integrated with other computerized object design systems to both design or study designs of medical devices or medical device products and their relationship with humans. They serve as fast and cost-efficient computer-based tools for the assessment of human functional systems and human-system interaction. This book provides an industry first introductory and practitioner focused overview of human simulation tools, with detailed chapters describing body functional elements and organs, organ interactions and fields of application. Thus, DHM tools and a specific scientific/practical problem - functional study of the human body - are linked in a coherent framework. Eventually the book shows how DHM interfaces with common physical devices in medical practice, answering to a gap in literature and a common practitioner question. Case studies provide the applied knowledge for practitioners to make informed decisions.

Towards 4D Printing presents the current state of three-dimensional (3D) bioprinting and its recent offspring, 4D bioprinting. These are attractive approaches to tissue engineering because they hold the promise of building bulky tissue constructs with incorporated vasculature. Starting with the discussion of 3D and 4D printing of inanimate objects, the book presents several 3D bioprinting techniques and points out the challenges imposed by living cells on the bioprinting process. It argues that, in order to fine-tune the bioprinter, one needs a quantitative analysis of the conditions experienced by cells during printing. Once the printing is over, the construct evolves according to mechanisms known from developmental biology. These are described in the book along with computer simulations that aim to predict the outcome of 3D bioprinting. In addition, the book provides the latest information on the principles and applications of 4D bioprinting, such as for medical devices and assistive technology. The last chapter discusses the perspectives of the field. This book provides an up-to date description of the theoretical tools developed for the optimization of 3D bioprinting, presents the morphogenetic mechanisms responsible for the post-printing evolution of the bioprinted construct and describing computational methods for simulating this evolution, and discusses the leap from 3D to 4D bioprinting in the light of the latest developments in the field. Most importantly, Towards 4D Printing explains the importance of theoretical modeling for the progress of 3D and 4D bioprinting.

3D Printing Technology for Water Treatment Applications provides a state-of-the-art presentation on the application of 3D printing technology in water treatment. The book discusses numerous processes and their scope for improvement through the use of 3D-printing technology, including pollutant separation from water and an overview of the advantages and disadvantages of different 3D printed technology over current technologies. In addition, the future outlook for device development using 3D printing water purification is explored. Finally, sustainability issues relating to 3D printing-based water purification processes are discussed, describing specific technologies such as 3D printed membranes. This book will serve as a vital resource for scientists, engineers and environmental professionals working in water treatment technologies.

Microfluidic Biosensors provides a comprehensive overview of the most recent and emerging technologies in the design, fabrication and integration of microfluidics with transducers. The book discusses the design and principle of microfluidic systems and how to use them for lab-on-a-chip applications. The microfluidic fabrication technologies covered in this book provide an up-to-date view, allowing the community to think of new ways to overcome challenges faced in this field. The book's focus is on existing and emerging technologies not currently being analyzed extensively elsewhere, thus providing a unique perspective and much needed content. The editors have crafted this book to be accessible to all levels of academics, from graduate students, researchers and professors working in the fields of biosensors, microfluidics design, analytical chemistry, biomedical devices and biomedical engineering. It will also be useful for industry professionals working for microfluidic device manufacturers, or in the biosensor and biomedical devices industry.

In this engaging account of innovative triumphs, Guru Madhavan examines the ways in which engineers throughout history created world-changing tools, from ATMs and ZIP codes to the digital camera and the disposable diaper. Equal parts personal, practical, and profound, Applied Minds charts a path to a future where we borrow strategies from engineering to find inspired solutions to our most pressing challenges.

Modeling of Mass Transport Processes in Biological Media focuses on applications of mass transfer relevant to biomedical processes and technology-fields that require quantitative mechanistic descriptions of the delivery of molecules and drugs. This book features recent advances and developments in biomedical therapies with a focus on the associated theoretical and mathematical techniques necessary to predict mass transfer in biological systems. The book is authored by over 50 established researchers who are internationally recognized as leaders in their fields. Each chapter contains a comprehensive introductory section for those new to the field, followed by recent modeling developments motivated by empirical experimental observation. Offering a unique opportunity for the reader to access recent developments from technical, theoretical, and engineering perspectives, this book is ideal for graduate and postdoctoral researchers in academia as well as experienced researchers in biomedical industries.

Biosensors for Emerging and Re-Emerging Infectious Diseases provides a review of how cornerstone optical, electronic, nanomaterial and data processing technologies can address detection issues occurring in a pandemic event. This book gives insights into the fundamental physical, chemical and biological mechanisms needed for such a type of detection. The content covers potential biomarkers which can be used for the infectious disease diagnostic, helping readers find the appropriate approach for the diagnosis of infectious diseases. It presents a novel approach to transferring the sensing platform from lab to application in clinics and to point of care detection. The book then moves on to discuss the function and efficiency of the biosensing platform in early diagnosis of infectious diseases compared to the standard methods. The required time, the technician skills and the steps which must be performed are other key factors of the biosensing platform which are well explained.

Humanitarian engineering is to provide disadvantaged individuals and communities with engineering solutions that improve lives and livelihoods. The provision of water, energy, food, shelter, energy and information are some of the issues targeted by this "discipline". Humanitarian Engineers could be the key towards achieving the Sustainable Development Goals. Currently, UNESCO is working to strengthen engineering education through curricula development and capacity building. It is also incorporating sustainability topics into engineering education by highlighting the need for green technology in engineering applications. The careful use of resources in a way that does not compromise the environment or deplete the materials for future generations is called sustainable engineering. Both sustainable engineering and humanitarian engineering require a highly interdisciplinary approach since they aim to improve the quality of life for all. The current book looks for the most recent challenges and approaches in the field of humanitarian engineering. A wide variety of topics that fall under the domain are technology-based solutions that tackle humanitarian problems. Pandemics, ageing of population, climate change, social inclusion, extreme poverty and hunger, maternal health and child mortality, education for all, are some indicative topics that could be addressed by technology. Early warning and alerting mechanisms for physical disasters, green engineering approaches, mobile health solutions for remote and underserved populations, are some paradigms that fall under the researched theme. The book is accepting research, real-life case studies, innovative models and approaches, and other work that lies in the presented theme. The proposed collection of chapters will provide an overview of the present thinking and state-of-the-art developments in humanitarian engineering. The book aims at providing latest research findings and their practical implementations, as well as new formulations, solutions, and case studies for tackling humanitarian contemporary issues. The book will give a unique opportunity to stakeholders, researchers and the academic community working in the aforementioned domains to understand the implications and solutions to a variety of topics. The book is anticipated to trigger further research on issues directly related to the proposed humanitarian topics.

Personalized Health Systems for Cardiovascular Disease is intended for researchers, developers, and designers in the field of p-health, with a specific focus on management of cardiovascular diseases. Biomedical engineers will benefit from coverage of sensors, data transmission, signal processing, data analysis, home and mobile applications, standards, and all other subject matters developed in this book in order to provide an integrated view of the different and multidisciplinary problems related to p-health systems. However, many chapters will also be interesting to physicians and other professionals who operate in the health domain. Students, MS and PhD level, mainly in technical universities, but also in medical schools, will find in this book a complete view of the manifold aspects of p-health, including technical problems related to sensors and software, to automatic evaluation and correct interpretation of the data, and also some legal and regulatory aspects. This book mainly focuses on the development of technology used by people and patients in the management of their own health. New wearable and implantable devices allow a continuous monitoring of chronic patients, with a direct involvement of clinical centers and physicians. Also, healthy people are more and more interested in keeping their own wellness under control, by adopting healthy lifestyles and identifying any early sign of risk. This is leading to personalized solutions via systems which are tailored to a specific patient/person and her/ his needs. However, many problems are still open when it comes to p-health systems. Which sensors and parameters should be used? Which software and analysis? When and how? How do you design an effective management plan for chronic pathologies such as cardiovascular diseases? What is useful feedback for the patient or for the clinician? And finally, what are the limits of this approach? What is the view of physicians? The purpose of this book is to provide, from a technical point of view, a complete description of most of the elements which are part of such systems, including the sensors and the hardware, the signal processing and data management procedures, the classification and stratification models, the standards and the regulations, focusing on the state of the art and identifying the new directions for innovative solutions. In this book, readers will find the fundamental elements that must be taken into account when developing devices and systems in the field of p-health.

The digital transformation of the 21st century has affected all facets of society and has been highly advantageous in many industries, including urban planning and regional development. The practices, strategies, and developments surrounding urban e-planning in particular have been constantly shifting and adapting to new innovations as they arrive. Trends and Innovations in Urban E-Planning provides an updated panorama of the main trends, challenges, and recent innovations in the field of e-planning through the critical perspectives of diverse experts. This book adds new and updated evidence on recent changes in this field and provides critical insights on these innovations. Covering topics such as citizen engagement, land property management, and spatial planning, this book is an essential resource for students and educators of higher education, researchers, urban planners, engineers, public officials, community groups, and academicians.