Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

The author designed his first shell and tube heat exchanger in 1965 using a slide rule. The book covers the development of calculations methods from then until the present time. It is a technical autobiography which includes personal accounts of interesting developments and challenging designs. The book contains only a basic coverage of heat transfer and pressure drop correlations since these may be found in many other more general books on heat transfer and fluid dynamics. Instead the emphasis is on how to identify key variables and the impact they have on that elusive 'optimum design'. The need to visualise what is taking place in a heat exchanger is an important part of the book and many novel ways of doing this are suggested. The mechanical aspects of shell and tube design are covered in sufficient detail for a thermal design engineer to have confidence that what they are proposing is realistic and can be manufactured. Limitations are discussed where it is advisable to seek specialist advice. The work of the process engineer is also covered in many sections and the need for coordination between process and thermal designers is a feature of the book. There is guidance on how to use modern sophisticated computer design programs and the potential pitfalls they will always contain. There are many examples of complex designs which require 'fudged' computer runs and supplementary hand calculations. There are a number of suggestions as to how some of the current programs may be improved. The SI system of units has been used throughout wherever practical. The main target market is practicing thermal design engineers. The book should also be useful to many other engineers who have to deal with heat exchangers particularly process engineers. The book is suitable for students on first degree and masters degree courses in engineering particularly those studying chemical engineering.

Digital Human Modeling and Medicine: The Digital Twin explores the body of knowledge and state-of-the-art in Digital Human Modeling (DHM) and its applications in medicine. DHM is the science of representing humans with their physical properties, characteristics and behaviors in computerized, virtual models. These models can be used standalone or integrated with other computerized object design systems to both design or study designs of medical devices or medical device products and their relationship with humans. They serve as fast and cost-efficient computer-based tools for the assessment of human functional systems and human-system interaction. This book provides an industry first introductory and practitioner focused overview of human simulation tools, with detailed chapters describing body functional elements and organs, organ interactions and fields of application. Thus, DHM tools and a specific scientific/practical problem - functional study of the human body - are linked in a coherent framework. Eventually the book shows how DHM interfaces with common physical devices in medical practice, answering to a gap in literature and a common practitioner question. Case studies provide the applied knowledge for practitioners to make informed decisions.

3D Printing Technology for Water Treatment Applications provides a state-of-the-art presentation on the application of 3D printing technology in water treatment. The book discusses numerous processes and their scope for improvement through the use of 3D-printing technology, including pollutant separation from water and an overview of the advantages and disadvantages of different 3D printed technology over current technologies. In addition, the future outlook for device development using 3D printing water purification is explored. Finally, sustainability issues relating to 3D printing-based water purification processes are discussed, describing specific technologies such as 3D printed membranes. This book will serve as a vital resource for scientists, engineers and environmental professionals working in water treatment technologies.

Towards 4D Printing presents the current state of three-dimensional (3D) bioprinting and its recent offspring, 4D bioprinting. These are attractive approaches to tissue engineering because they hold the promise of building bulky tissue constructs with incorporated vasculature. Starting with the discussion of 3D and 4D printing of inanimate objects, the book presents several 3D bioprinting techniques and points out the challenges imposed by living cells on the bioprinting process. It argues that, in order to fine-tune the bioprinter, one needs a quantitative analysis of the conditions experienced by cells during printing. Once the printing is over, the construct evolves according to mechanisms known from developmental biology. These are described in the book along with computer simulations that aim to predict the outcome of 3D bioprinting. In addition, the book provides the latest information on the principles and applications of 4D bioprinting, such as for medical devices and assistive technology. The last chapter discusses the perspectives of the field. This book provides an up-to date description of the theoretical tools developed for the optimization of 3D bioprinting, presents the morphogenetic mechanisms responsible for the post-printing evolution of the bioprinted construct and describing computational methods for simulating this evolution, and discusses the leap from 3D to 4D bioprinting in the light of the latest developments in the field. Most importantly, Towards 4D Printing explains the importance of theoretical modeling for the progress of 3D and 4D bioprinting.

Microfluidic Biosensors provides a comprehensive overview of the most recent and emerging technologies in the design, fabrication and integration of microfluidics with transducers. The book discusses the design and principle of microfluidic systems and how to use them for lab-on-a-chip applications. The microfluidic fabrication technologies covered in this book provide an up-to-date view, allowing the community to think of new ways to overcome challenges faced in this field. The book's focus is on existing and emerging technologies not currently being analyzed extensively elsewhere, thus providing a unique perspective and much needed content. The editors have crafted this book to be accessible to all levels of academics, from graduate students, researchers and professors working in the fields of biosensors, microfluidics design, analytical chemistry, biomedical devices and biomedical engineering. It will also be useful for industry professionals working for microfluidic device manufacturers, or in the biosensor and biomedical devices industry.

Biosensors for Emerging and Re-Emerging Infectious Diseases provides a review of how cornerstone optical, electronic, nanomaterial and data processing technologies can address detection issues occurring in a pandemic event. This book gives insights into the fundamental physical, chemical and biological mechanisms needed for such a type of detection. The content covers potential biomarkers which can be used for the infectious disease diagnostic, helping readers find the appropriate approach for the diagnosis of infectious diseases. It presents a novel approach to transferring the sensing platform from lab to application in clinics and to point of care detection. The book then moves on to discuss the function and efficiency of the biosensing platform in early diagnosis of infectious diseases compared to the standard methods. The required time, the technician skills and the steps which must be performed are other key factors of the biosensing platform which are well explained.

In this engaging account of innovative triumphs, Guru Madhavan examines the ways in which engineers throughout history created world-changing tools, from ATMs and ZIP codes to the digital camera and the disposable diaper. Equal parts personal, practical, and profound, Applied Minds charts a path to a future where we borrow strategies from engineering to find inspired solutions to our most pressing challenges.

Quantum Materials, Devices, and Applications covers the advances made in quantum technologies, both in research and mass production for applications in electronics, photonics, sensing, biomedical, environmental and agricultural applications. The book includes new materials, new device structures that are commercially available, and many more at the advanced research stage. It reviews the most relevant, current and emerging materials and device structures, organized by key applications and covers existing devices, technologies and future possibilities within a common framework of high-performance quantum devices. This book will be ideal for researchers and practitioners in academia, industry and those in materials science and engineering, electrical engineering and physics disciplines.

Biomedical Sensors and Smart Sensing: A Beginner's Guide, a book in the 10-volume Primers in Biomedical Imaging Devices and Systems series, covers a wide range of interdisciplinary applications in imaging modalities, nuclear medicine, computed tomographic systems, x-ray systems, magnetic resonance imaging, ultrasound, and virtual reality. The series explores the essential fundamental techniques required to analyze and process signals and images for diagnosis, scientific discovery and medical applications. Volumes in this series cover a wide range of interdisciplinary areas, combining foundational content with practical case studies to demonstrate the applications of these technologies in real-world situations. In addition, the 10-volume series considers various medical devices, electronics, circuits, sensors and algorithms. Several applications ranging from basic biological science to clinical practice are included to facilitate ongoing research.

Modeling of Mass Transport Processes in Biological Media focuses on applications of mass transfer relevant to biomedical processes and technology-fields that require quantitative mechanistic descriptions of the delivery of molecules and drugs. This book features recent advances and developments in biomedical therapies with a focus on the associated theoretical and mathematical techniques necessary to predict mass transfer in biological systems. The book is authored by over 50 established researchers who are internationally recognized as leaders in their fields. Each chapter contains a comprehensive introductory section for those new to the field, followed by recent modeling developments motivated by empirical experimental observation. Offering a unique opportunity for the reader to access recent developments from technical, theoretical, and engineering perspectives, this book is ideal for graduate and postdoctoral researchers in academia as well as experienced researchers in biomedical industries.

Personalized Health Systems for Cardiovascular Disease is intended for researchers, developers, and designers in the field of p-health, with a specific focus on management of cardiovascular diseases. Biomedical engineers will benefit from coverage of sensors, data transmission, signal processing, data analysis, home and mobile applications, standards, and all other subject matters developed in this book in order to provide an integrated view of the different and multidisciplinary problems related to p-health systems. However, many chapters will also be interesting to physicians and other professionals who operate in the health domain. Students, MS and PhD level, mainly in technical universities, but also in medical schools, will find in this book a complete view of the manifold aspects of p-health, including technical problems related to sensors and software, to automatic evaluation and correct interpretation of the data, and also some legal and regulatory aspects. This book mainly focuses on the development of technology used by people and patients in the management of their own health. New wearable and implantable devices allow a continuous monitoring of chronic patients, with a direct involvement of clinical centers and physicians. Also, healthy people are more and more interested in keeping their own wellness under control, by adopting healthy lifestyles and identifying any early sign of risk. This is leading to personalized solutions via systems which are tailored to a specific patient/person and her/ his needs. However, many problems are still open when it comes to p-health systems. Which sensors and parameters should be used? Which software and analysis? When and how? How do you design an effective management plan for chronic pathologies such as cardiovascular diseases? What is useful feedback for the patient or for the clinician? And finally, what are the limits of this approach? What is the view of physicians? The purpose of this book is to provide, from a technical point of view, a complete description of most of the elements which are part of such systems, including the sensors and the hardware, the signal processing and data management procedures, the classification and stratification models, the standards and the regulations, focusing on the state of the art and identifying the new directions for innovative solutions. In this book, readers will find the fundamental elements that must be taken into account when developing devices and systems in the field of p-health.

Restoration of Facial Defects with Digital Technology gives global descriptions of each method so that readers can project, design, and manufacture a maxillofacial prosthesis and customize maxillofacial surgery. It also covers using CAD-CAM technology to reduce the cost and time of making a facial prosthesis. The complete workflow for producing the ear, nasal, and oculofacial prosthesis (implant and mechanically supported), and for oncologic maxillofacial surgery is described. The atlas form of the book describes each procedure in a step-by-step manner so that readers may reproduce the process and obtain improved results with respect to the analogic procedures. This book communicates the most updated knowledge and the method of digital technology applied to the maxillofacial rehabilitation workflow, in a way that all may use it as a guide for replicating the methodologies presented in the book. This book will help also informatics technicians and biomedical engineers to project and customize the virtual construction of the prosthesis. It also describes how to use the new technology to reduce time and cost of the operatory room. The information in this book will also let readers: know the new methodologies to use digital technology instead of analogic procedures by anaplastologists; accomplish unusual hygiene procedures of craniofacial implants (hygienists); propose prosthetic alternative solution instead of the plastic surgery to the patient who lost ear, nose, or facial parts for oncologic or traumatic reasons; simplify the plastic reconstructive surgery and module as a function of the final prosthetic rehabilitation supported by craniofacial implants. The book has been written by experts in the field, pulling together information from disparate sources into one reference, making it ideal for anyone working in maxillofacial rehabilitation of the face.

Principles and Technologies for Electromagnetic Energy Based Therapies covers the theoretical foundations of electromagnetic-energy based therapies, principles for design of practical devices and systems, techniques for in vitro and in vivo testing of devices, and clinical application examples of contemporary therapies employing non-ionizing electromagnetic energy. The book provides in-depth coverage of: pulsed electric fields, radiofrequency heating systems, tumor treating fields, and microwave heating technology. Devices and systems for electrical stimulation of neural and cardiac issue are covered as well. Lastly, the book describes and discusses issues that are relevant to engineers who develop and translate these technologies to clinical applications. Readers can access information on incorporation of preclinical testing, clinical studies and IP protection in this book, along with in-depth technical background for engineers on electromagnetic phenomena within the human body and selected therapies. It covers both engineering and biological/medical materials and gives a full perspective on electromagnetics therapies. Unique features include content on tumor treating fields and the development and translation of biomedical devices.