Ground-breaking, evidence-based book asks how many lives were lost because of Chinas negligence about lab-leaked SARS-CoV-2. In a disturbing reconstruction of events by two of the most reputable scientists in the world, a new book reveals for the first time how Chinese authorities and elite Wuhan scientists knew about SARS-CoV-2s menacing biological features from the start but remain silent to this day. In The Origin of the Virus (Clinical Press) Dr Steven Quay and Prof Angus Dalgleish, working with Italian reporter Paolo Barnard, show how China engaged in lies, omissions and obfuscations to cover up the laboratory origin of the virus. Had they immediately alerted the international community and policymakers of the extremely pathogenic molecular machinery present in SARS-CoV-2's genome, very large numbers of lives may have been spared, argue Quay, Dalgleish and Barnard. The authors provide a shocking account of the extreme experiments that led to the outbreak of the worst pandemic since the 1918 Spanish influenza. They broaden the censure to explain why some American and British scientists thwarted a proper investigation of the origin of COVID-19. Despite its impeccable scientific grounding the book is both a readable and gripping account that, for the first time, allows the public to partake in what lies at the heart of the many scandals surrounding the birth of the most deadly virus in modern times.

'I am blown away by the level of detail Phil Cavell brings to his work.' - Elinor Barker MBE, multiple world champion and Olympic gold medallist 'The Midlife Cyclist is a triumph' - Cycling Plus 'An amazing accomplishment... a simple-to-understand precis of your midlife as a cyclist - you won't want to put it down.' - Phil Liggett, TV cycling commentator 'Phil is eminently qualified to write The Midlife Cyclist. Well, he is certainly old enough.' - Fabian Cancellara, Tour de France rider and two-time Olympic champion Renowned cycling biomechanics pioneer, Phil Cavell, explores the growing trend of middle-aged and older cyclists seeking to achieve high-level performance. Using contributions from leading coaches, ex-professionals and pro-team doctors, he produces the ultimate manifesto for mature riders who want to stay healthy, avoid injury - and maximise their achievement levels. Time's arrow traditionally plots an incremental path into declining strength and speed for all of us. But we are different to every other generation of cyclists in human history. An ever-growing number of us are determined to scale the highest peaks of elite physical fitness into middle-age and beyond. Can the emerging medical and scientific research help us achieve the holy triumvirate of speed and health with age? The Midlife Cyclist offers a gold standard road-map for the mature cyclist who aims to train, perform and even race at the highest possible level.

The exclusive, first-hand, behind-the-scenes story of how Pfizer raced to create the first Covid-19 vaccine, told by Pfizer's CEO Dr. Albert Bourla A riveting, fast-paced, inside look at one of the most incredible private sector achievements in history, Moonshot recounts the intensive nine months in 2020 when the scientists at Pfizer, under the visionary leadership of Dr. Albert Bourla, made "the impossible possible"-creating, testing, and manufacturing a safe and effective Covid-19 vaccine that previously would have taken years to develop. Dr. Bourla chronicles how the brilliant, dedicated minds at Pfizer, under the enormous strains of the global pandemic, overcame a series of crises that were compounded by social and political unrest, and reveals the doubts, decisions, obstacles, and failures they encountered. As Dr. Bourla makes clear, Pfizer's success wasn't due to luck; it was because of preparation driven by four simple values-Courage, Excellence, Equity, and Joy. Moonshot is a story of leadership under the most unprecedented circumstances-how Dr. Bourla, a Greek immigrant, a child of Holocaust survivors, and a veterinarian, became the head of one of the world's largest corporations and initiated a dramatic transformation of the organization just before a global health crisis would serve to test the organization, its scientists and its leader, like never before. Moonshot describes best practices that can be used to address the multiple, unprecedented challenges our world faces, reveals Pfizer's implementation of scientific breakthroughs at a record-breaking pace, and offers leadership lessons that can help anyone successfully manage their own seemingly unsolvable problems. As Dr. Bourla explains, "I am sharing the story of our moonshot-the challenges we faced, the lessons we learned, and the core values that allowed us to make it happen-in hopes that it might inspire and inform your own moonshot, whatever that may be."

The much awaited third edition of the leading reference book in dermoscopy has undergone comprehensive revisions to all chapters, with updates and expanded content providing the reader with a more comprehensive and in-depth coverage of skin conditions, ranging from skin neoplasia to hair, nails, infections and inflammatory diseases. This compilation of contemporary dermoscopy knowledge will benefit the novice in building expertise and benefit experienced practitioners also by providing nuanced insights. Prepare to embark on a journey of learning as leading international experts in the field of dermoscopy explain via text and annotated exemplar images the amazing world of subsurface cutaneous colors and structures visible through a dermatoscope!

In Turning the World Upside Down Nigel Crisp argued that the most affluent and powerful countries in the world can learn a great deal about health from lower income countries with their different insights and experiences and their ability to innovate free from vested interests and received wisdom. In Turning the World Upside Down Again, he argues that they need to go further and listen to and learn from disempowered communities in their own countries. He describes how combining the learning from different countries and communities can lead us to a new ecologically based vision for health and new and practical ways of improving health for ourselves, our communities and our planet. This second edition, 12 years after the first, is extensively re-written and fully updated, drawing on examples from around the world and reflecting what has already been learned from the COVID-19 pandemic and from the onset of climate change. Turning the World Upside Down Again continues the search for understanding begun in the first edition and describes how western scientific medicine, which has served us so well in the 20th Century, must adapt and evolve further and faster to cope with the demands of the 21st Century.

As a result of the COVID-19 pandemic, medical statistics and public health data have become staples of newsfeeds worldwide, with infection rates, deaths, case fatality and the mysterious R figure featuring regularly. However, we don't all have the statistical background needed to translate this information into knowledge. In this lively account, Stephen Senn explains these statistical phenomena and demonstrates how statistics is essential to making rational decisions about medical care. The second edition has been thoroughly updated to cover developments of the last two decades and includes a new chapter on medical statistical challenges of COVID-19, along with additional material on infectious disease modelling and representation of women in clinical trials. Senn entertains with anecdotes, puzzles and paradoxes, while tackling big themes including: clinical trials and the development of medicines, life tables, vaccines and their risks or lack of them, smoking and lung cancer, and even the power of prayer.

The Afterlife of the Leiden Anatomical Collections starts where most stories end: after death. It tells the story of thousands of body parts kept in bottles and boxes in nineteenth-century Leiden - a story featuring a struggling medical student, more than one disappointed anatomist, a monstrous child, and a glorious past. Hieke Huistra blends historical analysis, morbid anecdotes, and humour to show how anatomical preparations moved into the hands of students and researchers, and out of the reach of lay audiences. In the process, she reveals what a centuries-old collection can teach us about the future fate of the biobanks we build today.

A focus throughout on lifespan perspectives and a consideration of palliative care across all ages. Consideration of different cultural perspectives, beliefs, thoughts and practices outside Western societies and dominant paradigms. Integrates primary research throughout, including a focus on contemporary research from social media. Complements mainstream psychological approaches to life-limiting illness by exploring death, dying and palliative care with a critical health psychology lens.

For two decades, Understanding Clinical Papers has been helping students and professionals understand the research that supports evidence-based practice. Now in its fourth edition, this popular introductory textbook covers every major aspect of reading and evaluating clinical research literature, from identifying the aims and objectives of a paper to analysing the data with different multivariable methods. Numerous excerpts from actual clinical research papers make learning real and immediate, supported by a unique visual approach that reinforces key points and connects examples with the chapter material. The fourth edition includes extensively revised content throughout, including four brand-new chapters covering qualitative studies, Poisson regression, studies of complex interventions, and research using previously collected data. New and updated material discusses the difference between clinical and statistical significance, the consequences of multiple testing and methods of correction, how topic guides are used to explore and explain participants' experiences, standardised guidelines for writing trials and reviews, and much more. Offering clear explanations of important research-related topics, this reader-friendly resource: Offers a clear, concise, and accessible approach to learning how to read and analyse clinical research literature Features new coverage of qualitative research, including descriptive studies, sampling and populations, and identifying, summarising, and measuring qualitative characteristics Provides new material on missing data, sub-group analysis, feasibility and pilot studies, cluster randomised trials, and adaptive trial designs Includes new tables, abstracts, and excerpts from recent clinical research literature Understanding Clinical Papers is essential reading for all healthcare professionals and students, particularly those involved in clinical work and medical research, as well as general readers wanting to improve their understanding of research literature.

This addition to the British Dietetic Association Advanced Nutrition and Dietetics book series is written for clinicians and researchers who work with any aspect of obesity and its comorbid conditions. Featuring contributions from leading researchers and practitioners from around the globe Advanced Nutrition and Dietetics in Obesity offers a uniquely international perspective on what has become a worldwide public health crisis. Chapters cover a full range of new ideas and research on the underlying drivers of obesity in populations including discussions on the genetic and clinical aspects of obesity, along with expert recommendations on how to effectively manage and prevent this chronic and persistent disease. Providing a comprehensive overview of the key literature in this field, Advanced Nutrition and Dietetics in Obesity is an invaluable resource for all those all those whose work should or does embrace any aspect of obesity.

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. A full-color case-based review of the essentials of pathophysiology covering all major organs and systems More than 130 case studies with Q&A A Doody's Core Title for 2019! The goal of this trusted text is to introduce you to clinical medicine by reviewing the pathophysiologic basis of 132 diseases (and associated signs and symptoms) commonly encountered in medical practice. The authors, all experts in their respective fields, have provided a concise review of relevant normal structure and function of each body system, followed by a description of the pathophysiologic mechanisms that underlie several common diseases related to that system. The accessible presentation features high-quality full-color illustrations, and numerous tables and diagrams. Each chapter of Pathophysiology of Disease concludes with a collection of case studies and questions designed to test your understanding of the pathophysiology of each clinical entity discussed. These case studies allow you to apply your knowledge to specific clinical situations. Detailed answers to each case study question are provided at the end of the book. This unique interweaving of physiological and pathological concepts will put you on the path toward thinking about signs and symptoms in terms of their pathophysiologic basis, giving you an understanding of the "why" behind illness and treatment. HERE ARE SOME OF THE MANY UPDATES AND ADDITIONS: *Twelve additional case studies, bringing the total to 132, one for each of the clinical entities discussed in the book's 24 chapters *More than 2/3 of the chapters are enhanced and refreshed by the input of new contributors *Totally revised chapter on neoplasia *New chapter sections on urticaria, spinocerebellar ataxia, idiopathic pulmonary fibrosis, and spondyloarthropathies *New tables summarizing adverse prognostic signs in acute pancreatitis, genetic syndromes associated with pancreatic cancer, and causes of end-stage renal disease *New diagnosis and etiologic classification of diabetes mellitus, and review of mechanisms of newest pharmacologic agents for its treatment *Updates on fine-needle aspiration biopsy of thyroid nodules, and thyroid disorders in pregnancy *Updated references throughout the book

Selected by the Association of University Programs in Health Administration for the Bugbee-Falk Book Award Is the health sector a curse or a blessing? The American health sector now accounts for a fifth of the economy. American healthcare spending per capita far exceeds that of other developed countries. Yet our health, as measured by life expectancy and infant mortality, is poor by comparison with the developed world. Other measures of quality including hospital-acquired infection are too common. Healthcare costs financially cripple households despite advances associated with the Affordable Care Act. There is widespread dissatisfaction with the American healthcare system and support for more change. It is also the case that the health sector has been a leader in the evolution of the American economy. Economic development is driven by innovative technology. We tend to applaud new technology and the improvement it brings to our lives. Important recent technologies often grow rapidly and faster than the wider economy. This leads to larger shares of the economy. Yet there is considerable apprehension about costs and economic impact of health spending. This book details important health sector institutions and uniquely, explores linkages between healthcare and broader economic growth. The book addresses asymmetric information between providers and consumers as well as between insurers and beneficiaries. There is a focus on monopoly power in labor markets which contributes to inefficiencies in the system. The author also discusses cost-effectiveness and allocative efficiency as well as emphasizing productivity and its relationship to the wider economy.

This book focuses on the era during which the cause of tuberculosis had been identified, and public health officials were seeking to prevent it, but scientists had not yet found a cure. By examining tuberculosis comparatively in two Atlantic port cities, Buenos Aires and Philadelphia, it explores the medical, political and economic settings in which patients, physicians and urban officials lived and worked. Reber discusses the causes of tuberculosis, treatments and public health efforts to stop contagion, and how factors such as gender, age, class, nationality, beliefs and previous experiences shaped patient responses, and often defined the type of treatment.

The Doctor of Hiroshimais the extraordinary true story of Dr Michihiko Hachiya, whose hospital was less than a mile from the centre of the atomic bomb that hit on that warm August day. In immense shock and pain, he and his wife Yaeko dragged themselves to the devastated hospital building and what colleagues they could find.

In time, they begin to heal, and start to treat the impossible numbers of patients - a small girl covered in burns, an elderly man with pneumonia, a young boy and his little sister looking for their parents. They also began to investigate the strange unexplainable symptoms afflicting his patients - things he never dreamed he would see...

Told simply and poignantly in Dr Hachiya's own words, The Doctor of Hiroshima is a unique and deeply moving human story of survival about a small, committed band of hospital staff in the face of unthinkable destruction and loss.

In rural and sparsely populated countries, telemedicine can be a vital and life-saving link to health care, and in those regions where demands on hospitals are ever increasing, it can provide a safe and comfortable alternative to hospital-based therapy. The second edition of this introductory guide to telemedicine and telecare services is invaluable to new practitioners in this growing field of medicine. The book describes the benefits of telemedicine and highlights the potential problems. The authors provide numerous examples of how telemedicine is used in the United States, Australia, and Scandinavia.

Key Features: Student-centered approach that simplifies sociological theory and principles through practical examples, supporting understanding for those without a formal background in sociology Scenarios guide students and encourage questions for them to consider and discuss before they proceed for a deeper understanding Common themes are threaded throughout, reinforcing learning and aiding students to 'revise, re-apply and thus remember'

This book puts the critical into dementia studies. It makes a timely and novel contribution to the field, offering a provocative and thought-provoking critique of current thinking and debate on dementia. Collectively the contributions gathered together in this text make a powerful case for a more politically engaged, deconstructive and critical treatment of dementia and the systems and structures that currently govern and frame it. The book is interdisciplinary and draws together leading dementia scholars alongside dementia activists from around the world. It frames dementia as first and foremost a political category. The book advances both theoretical and methodological thinking in the field as well as sharing learning from empirical research. Outlining the limits to existing efforts to frame and theorise the condition it proposes a new critical movement for the field of dementia studies and practice. The book will be of direct interest to researchers and scholars in the field of dementia studies and wider fields of health, disability and care. It will provide a novel resource for students and practitioners in the fields of dementia, health care and social care. The book also has implications for dementia policymaking, commissioning and community development.

Beer is made up of various bioactive substances containing antioxidants and specific ingredients with potentially beneficial effects on the human body if consumed in moderation. In the production process, the addition of hops, cereals, and malt leads to an increased content of naturally occurring antioxidant compounds in beer, mainly phenolic compounds. This book presents information on the history, compositional analysis, and brewing process of craft beers. It covers aspects of fruit fortification to different craft brewed beers and how it will enhance the nutritional composition, antioxidant properties, color and sensory attributes of beers. The alcohol industry continues to grow quickly worldwide, this book provides relevant research literature about the recent studies and experimentation about beers which will be helpful to students, researchers, industrialists, producers, and many others. The incorporation of fruits for the fortification of beers is a topic of interest resulting in the need for more innovative and effective methods and steps in the production of newer variants of beers.

Omega-3 fatty acids can limit the inflammation that is the underlying cause of many severe diseases of modern civilization, including diabetes and cardiovascular disease. The Omega-Factor: Promoting Health, Preventing Premature Aging and Reducing the Risk of Sudden Cardiac Death presents information on the mechanisms whereby inflammation damages organs and the blood vessels serving them, as well as the hard science on the mechanisms by which the omega-3 fatty acids protect those tissues. It also features peer-reviewed evidence from clinical trials on these topics. The book gives cutting-edge information from state-of-the-art developments such as the test that can be done to measure the Omega 3 status of one's own tissues, the "Omega 3 Index", which can give many years of early warning so that one can take preventive steps and decrease the odds of a heart attack, stroke, or kidney disease. It explains why a Mediterranean diet plan rich in omega 3 and omega 6 fatty acids is protective, and it features a six-day meal plan with recipes that will improve body levels of omega 3s. This book helps readers understand the differences between various sources of omega-3 fatty acids, namely flax seed vs. fish oil vs. algae-derived oils. Features: * Provides evidence-based information on why blood vessels require omega-3 fatty acids to maintain health. * Details best sources of the various fatty acids, including plant-based sources. * Includes "at-home tests" to assess cardiovascular status. * Presents literature to how to improve chances of avoiding heart attacks, peripheral arterial disease, strokes, kidney disease, and Type-2 Diabetes. The Omega-Factor: Promoting Health, Preventing Premature Aging and Reducing the Risk of Sudden Cardiac Death is an essential resource for healthcare professionals, clinicians, and dietitians, as well as for the reader who aims to achieve the goal of a much longer health-span, not just a longer lifespan.

Your indispensable guide to taking charge of the second half of your life. From Dr. Rosanne M. Leipzig, a top doctor with more than 35 years of experience caring for older people, Honest Aging is an indispensable guide to the second half of life, describing what to expect physically, psychologically, functionally, and emotionally as you age. Leipzig, an expert in evidence-based geriatrics, highlights how 80-year-olds differ from 60-year-olds and why knowing this is important for your health. With candor, humor, and empathy, this book will provide you with the knowledge and practical advice to optimize aging. The book * helps you recognize age-related changes in your body and mind and understand what's typical with aging and what's not; * offers guidance for common health concerns, including problems with memory, energy, mood, sleep, incontinence, mobility and falls, hearing and vision, aches and pains, gastrointestinal problems, weight, and sex; * shares advice on how to make decisions about health care, driving, and where to live; * includes helpful checklists and lists of medications to prepare for doctor and hospital visits; * recommends the best technology options, such as mobility devices, emergency device systems, and more; * counters common myths about aging; and * offers resources for additional information, self-help, and support. Enriched by illustrations, patient stories, and deep dives into science and the latest research, Honest Aging gives you the tools to take control of your health and well-being as you age.

In Decolonizing Trauma Work, Renee Linklater explores healing and wellness in Indigenous communities on Turtle Island. Drawing on a decolonizing approach, Linklater engages ten Indigenous health care practitioners in a dialogue regarding Indigenous worldviews, notions of wellness and wholistic health, critiques of psychiatry and psychiatric diagnoses, and Indigenous approaches to helping people through trauma, depression and experiences of parallel and multiple realities. Linklater offers purposeful and practical methods to help individuals and communities that have experienced trauma, through stories and strategies that are grounded in Indigenous worldviews and embedded with cultural knowledge. Decolonizing Trauma Work, one of the first books of its kind, is a resource for education and training programs, health care practitioners, healing centres, clinical services and policy initiatives.

This book focuses on an important but neglected aspect of the Spanish Civil War, the evolution of medical and surgical care of the wounded during the conflict. Importantly, the focus is from a mainly Spanish perspective - as the Spanish are given a voice in their own story, which has not always been the case. Central to the book is General Franco's treatment of Muslim combatants, the anarchist contribution to health, and the medicalisation of propaganda - themes that come together in a medico-cultural study of the Spanish Civil War. Suffusing the narrative and the analysis is the traumatic legacy of conflict, an untreated wound that a new generation of Spaniards are struggling to heal.

Therapy with couples on the brink of relationship dissolution involves unique challenges. Partners present with high levels of conflict, low levels of intimate connection, disdain and discouragement, and limited patience or hope. These couples have often tried therapy without lasting success, and announce that "this is our last chance". Partners want to see evidence in the first session that the therapist can offer something new and that change is possible. Peter Fraenkel presents a practical, creative, integrative approach that combines action-and insight-oriented techniques to help last-chance couples manage conflict, modulate intense negative emotions, address power struggles, develop mutual compassion, and restore emotional intimacy and pleasurable connection. Special attention is paid to developing a collaborative therapeutic alliance when partners have little motivation for therapy or faith that it can be effective. Through engaging in "nonbinding experiments in possibility", partners can then better evaluate whether to "stay or go".

An easy-to-read yet thorough guide to understanding and managing glaucoma and taking care of your vision. When you receive a glaucoma diagnosis, knowing where to turn and how to understand treatment options can be overwhelming. Fifty percent of people with glaucoma do not even know they have the disease, and those who do may still struggle with managing it. If left untreated, glaucoma can lead to irreversible blindness. The Glaucoma Guidebook is an invaluable resource for anyone living with glaucoma and for those who are at high risk of developing the disease. Dr. Constance Okeke, an expert with over 20 years of experience helping thousands of patients see better, provides the critical advice and best practices needed to take control of your vision. In simple, accessible language, the book explains: * What glaucoma is, including early symptoms * What causes increased eye pressure * Treatment options * How to prevent blindness * How to become an advocate for your own eye health If you have been recently diagnosed with glaucoma or are struggling with managing your glaucoma, this is the book for you. With over 50 color images and illustrations and easy-to-follow advice from both Dr. Okeke and actual glaucoma patients, this book will not only serve as a guide for those with glaucoma but also provide invaluable information for family members, caregivers, eyecare providers, and educators.

This handbook presents a thorough examination of the intricate interplay of race, ethnicity, and culture in mental health - historical origins, subsequent transformations, and the discourses generated from past and present mental health and wellness practices. The text demonstrates how socio-cultural identities including race, gender, class, sexual orientation, disability, religion, and age intersect with clinical work in a range of settings. Case vignettes and recommendations for best practice help ground each in a clinical focus, guiding practitioners and educators to actively increase their understanding of non-Western and indigenous healing techniques, as well as their awareness of contemporary mental health theories as a product of Western culture with a particular historical and cultural perspective. The international contributors also discuss ways in which global mental health practices transcend racial, cultural, ethnic, linguistic, and political boundaries. The Routledge International Handbook of Race, Culture and Mental Health is an essential resource for students, researchers, and professionals alike as it addresses the complexity of mental health issues from a critical, global perspective.