This book offers a highly informative guide to interventional radiology such as arterial embolization and arterial balloon occlusion for the prevention of massive hemorrhage and management of cervical myomectomy and cesarean hysterectomy. Recently, catheter intervention for hemostasis in obstetric patients has been increasingly used. Before myomectomy of large cervical leiomyoma or cesarean hysterectomy for placenta percreta with expected massive hemorrhage, a balloon occlusion catheter is inserted into arteries. In cesarean hysterectomy operations, ligation of internal iliac artery is not always effective in hemostasis of uterine bleeding: the success rate is about 40 -60%. Uterine blood flow during pregnancy is much different from that in non-pregnant women because large numbers of complicated collateral arteries develop during pregnancy, especially in patients with placenta previa. If the internal iliac artery and hypogastric artery are ligated, peripheral blood flow is still maintained, which causes intraoperative problems. The authors argue that effective transcatheter balloon occlusion requires a detailed knowledge of blood flow in both pregnant and non-pregnant women. As such the book provides extensive, detailed anatomical figures and videos offer readers vivid insights into methods of intercepting the uterine blood supply and the surgical methods. The book offers a new and indispensable reference guide for all obstetricians, not only for residents, but also for experienced professionals. It is also a valuable resource for radiologists and radiological technicians and radiology specialists.

This book offers a timely and detailed exploration and analysis of key contemporary issues and challenges in child sexual abuse, which holds great relevance for scholarly, legal, policy, professional and clinical audiences worldwide. The book draws together the best current evidence about the nature, aetiology, contexts, and sequelae of child sexual abuse. It explores the optimal definition of child sexual abuse, considers sexual abuse in history, and explores new theoretical understandings of children's rights and other key theories including public health and the Capabilities Approach, and their relevance to child sexual abuse prevention and responses. It examines a selection of the most pressing legal, theoretical, policy and practical challenges in child sexual abuse in the modern world, in developed and developing economies, including institutional child sexual abuse, female genital cutting, child marriage, the use of technology for sexual abuse, and the ethical responsibility and legal liability of major state and religious organisations, and individuals. It examines recent landmark legal and policy developments in all of these areas, drawing in particular on extensive developments from Australia in the wake of its Royal Commission Into Institutional Responses to Child Sexual Abuse. It also considers the best evidence about promising strategies and future promising directions in enhancing effective prevention, intervention and responses to child sexual abuse.

This book uses global household data to examine the prevalence, trends and geographic variation of female genital mutilation (FGM) around the world. It also addresses the underlying legal and policy aspects as well as explores the medical consequences, both immediate and long term, for those undergoing the practice. The book analyses the position of victims of this gender-based violence both from the medical and legal perspective and adopts a largely practical approach to the study of the practices, offering a fresh thinking into one of the challenges in global health and the law. In addition, it offers some insights into how health professionals can approach this category of victims and how legal practitioners can obtain a good legal result for their clients before domestic and international forums. The book addresses fundamental issues such as state liability and defences in enforcement proceedings for actions or omission of state or non-state actors, and due diligence standard in international human rights law, the main gateways available for obtaining relief for the victims of FGM. This book goes beyond the traditional debate between zero tolerance and those who wish to see the practice medicalised and tolerated and favours an advocacy programme standing firmly in favour of the right of FGM victims. This book offers a unique perspective likely to assist victims and their representatives to secure a remedy against perpetrators and the state. As such this book will be of interest to medical professionals, national and international lawyers, academics and policymakers in the field of public health.

Meningitis and Encephalitis are associated with high rates of mortality and neurological sequelae. The differential diagnosis includes a wide spectrum of infectious and non-infectious etiologies, some requiring urgent therapy for survival. The current management challenges in patients with meningitis and encephalitis include a low sensitivity of meningeal signs, overutilization of unnecessary screening cranial imaging, delays in diagnosis of urgent treatable causes, a large proportion of unknown etiologies, low sensitivity of current microbiological techniques especially in the setting of previous antibiotic therapy, underutilization of available molecular diagnostic tests, and empiric antibiotic therapy and hospitalization for viral meningitis cases. Even though there are published guidelines, compliance with them is not optimal and physicians do not follow standardized algorithms in their empirical approach. As meningitis and encephalitis is associated with high rates of adverse clinical outcomes, prevention, when feasible is of upmost importance. Adherence to protocols to prevent health-care associated meningitis and ventriculitis are effective but compliance with them is not uniformly performed. This book seeks to improve outcomes for meningitis and encephalitis cases handled by physicians who may or may not be thoroughly trained for these challenges. The text introduces the current guidelines but also discusses the gaps that leave clinicians struggling to implement the most appropriate approaches for these particular neurological infections. Each chapter delivers the tools necessary to identify and adhere to the most appropriate diagnostic technique, management protocols, and prevention approach for each situation. All chapters conclude with discourse on future directions in research and quality improvement. Written by experts in infectious diseases, the book covers topics that are the most devastating, including healthcare-acquired infections, autoimmune encephalitis, and infections as they present in HIV patients. Meningitis and Encephalitis is a well-rounded resource for all medical professionals encountering these neurological syndromes, including infectious disease specialists, neurologists, primary care physicians, and immunologists.

This volume provides a broad background of the basic sciences, clinical and therapeutic aspects, and management of uterine cervical cancer. It offers state-of-the-art information on the molecular genetics, biology, and clinical aspects of premalignant lesions of the uterine cervix, and provides a better understanding of the molecular and cellular events that underlie uterine cervical cancer. Uterine Cervical Cancer: Clinical and Therapeutic Perspectives contains extensive, updated information on the promising new developments in the diagnosis and management of uterine cervical cancer. It will serve as an invaluable resource for all clinicians and basic medical scientists caring for women with uterine cervical cancer, including attending surgeons, physicians, clinical fellows, and residents in the disciplines of gynecologic oncology, medical oncology, and surgical oncology.

There are more than 63,000 new cases of uterine and endometrial cancer each year in the United States, up from approximately 41,000 when the first edition of Uterine Cancer was published in 2009. A book focusing on these cancers was timely, with emergent sophistication in diagnosis increasingly impacting clinical decision-making. However, five years later, the need for an updated book on this topic is even stronger as oncologists recognize opportunities to impact the outcome on women that are increasingly diagnosed with these malignancies. Uterine Cancer: Screening, Diagnosis, and Treatment, Second Edition, part of the Current Clinical Oncology series, enhances the awareness on this somewhat neglected area of therapeutics, helping to integrate targeted therapies into the management of women with uterine cancer. Written by experts in the field in a highly practical and comprehensive manner, it is a must-have for all gynecological residents and fellows, as well as gynecological oncologists, medical oncologists, radiation oncologists, and family practice doctors who wish to provide their patients with the best possible care.

With insight and research from world-renowned experts, this book provides specific approaches to diagnosis and treatment, addressing pharmacologic and non-pharmacologic management. Specific conditions examined include asthma, rhinitis and sinusitis, anaphylaxis, atopic and contact dermatitis, urticaria and angioedema, hereditary angioedema, drug allergies, and primary immune deficiency. An overview of obstetric management of the high risk asthmatic and allergic patient is provided, and the book concludes with a discussion of the prevention of asthma and allergic diseases during childhood.

This book looks at the most common presentations of menstrual irregularities that a practitioner comes across in his day-to-day practice with proper definitions, clinical classification, aetio-pathology, clinical features, prognostic significance and their homeopathic management. The indications for the remedies are given in precise with case references from author's experience.

This book is a practical revision aid for trainees in gynaecology preparing for examinations. Presented as clinical scenarios, the text comprises a wealth of SAQs (Short Answer Questions) with answers, providing in depth coverage of cognitive and practical knowledge of common gynaecological cancers, and describing recent, evidence-based diagnostic and therapeutic approaches with detailed explanations. Divided into seven sections, the book begins with screening and abnormal cytology. Each of the following sections covers a different type of gynaecologic cancer. High quality illustrations, flowcharts, tables and photographs of recent operations, resected specimens and histopathology further enhance the comprehensive text. The information in this book is in accordance with guidelines from the NCCN (National Comprehensive Cancer Network), FIGO (International Federation of Gynaecology and Obstetrics), ACS (American Cancer Society), ASCCP (American Society of Colposcopy and Cervical Pathology), and WHO (World Health Organisation).

This second edition updates the reader on the most common intrauterine transmitted viral infection, CMV. The history of this disease, its pathophysiological background, epidemiology and symptoms, as well as diagnostic and therapeutic strategies, will be discussed in detail. Further a section specifically dedicated to prevention measures is included to the new edition. The chapter on virus-host interaction for defense and transmission is elaborately updated.

This text provides a comprehensive, state-of-the art review of pharmacotherapy for the overactive bladder, and serve as a valuable resource forclinicians, surgeons, and researchers with an interest in OAB. The early chapters will describe the pathophysiology of OAB, algorithm, and provide the readers with a practical guide for evaluating the OAB patient. The next section describes the unique challenges involved in the study of OAB and helps the reader navigate the complexities of the literature on the topic. All chapters are written by experts in their fields and include the most up-to-date scientific and clinical information. The text includes a review of the clinical guidelines for OAB, and a detailed description of the individual therapies, including antimuscarinics, Beta-3 agonists, (insert comma) and chemodenervation. Extensive tabulation of contemporary literature makes this a matchless resource that provides a detailed account of the current evidence for the use of each of these therapies. The text concludes with chapters on unique populations with OAB, and future directions in the research field.Contemporary Pharmacotherapy of Overactive Bladder unites a unique set of thought leaders in the field of voiding dysfunction to create a comprehensive resource that will be useful for a variety of clinicians who treat OAB, including urologists, urogynecologists, general gynecologists, family practitioners, and geriatricians.

This book aims to highlight all the existing information available on first and mid-trimester imaging of palate in prenatal ultrasound and to develop a methodical approach in imaging the palate. As formation of the palate is completed by 11 weeks of gestation and as there are no evolving changes in palatine anatomy at the mid-trimester, diagnosis of palatine clefts can now completely be shifted to late first-trimester. First-trimester evaluation of palate is now gaining importance and a number of techniques have currently been proposed by different authors. This book covers the existing literature and recent 2D and 3D techniques in evaluating palate and helps in the early detection of palatine clefts in the first trimester. Orofacial clefting is one of the most common birth defects and the burden of it in developing countries is substantial. This book helps in improving the counseling options for the obstetrician and the couple early in gestation. It includes 2D and 3D images of various types of palatine clefts and the nuances in imaging the secondary palate extensively. 3D images of the palate also help the multi-disciplinary team especially the maxillofacial surgeons involved in managing orofacial clefts. It also includes videos for easy understanding. This book is a ready reckoner for the imaging specialists and students /trainees involved in prenatal diagnosis. It provides essential information in diagnosing orofacial cleft both to the novice and to the skilled professionals involved in the field of diagnostic fetal ultrasound.

This concise, easy to follow review of obstetric anesthesia follows the outline set forth by the American Board of Anesthesiology (ABA), making it an invaluable resource for in-service exam and board exams. The book is divided into four sections, beginning with maternal physiology, followed by maternal-fetal considerations, then pathophysiology of complicated pregnancy, and finally problems of term and delivery. Written at the fellow-level, it provides anesthesiology residents, obstetric anesthesiology fellows, and any anesthesiologist providing care to obstetric patients testable information for the boards, as well as practical tips for clinical practice.

Schwangerschaft bei Diabetes? Dank neuer Therapien konnen sich Diabetikerinnen heutzutage ihren Kinderwunsch erfullen. Voraussetzung ist allerdings die kompetente, luckenlose Begleitung der Schwangerschaft. Experten bieten hierfur alle notwendigen Informationen (inkl. Gestationsdiabetes) - praxisbezogen, ubersichtlich und verstandlich. Exakt erlautern sie welche Massnahmen, wann und wie einzusetzen sind. Alles rund um die Pravention sowie Begleit- und Folgeerkrankungen: wichtige Parameter und deren Uberwachung, Diagnose, Therapie, medikamentose Intervention. Ein hilfreicher Ratgeber fur werdende Mutter sowie alle Fachleute, die sie betreuen."

The Female Reproductive System chart presents an overview of the structure and function of female reproductive anatomy. The primary image illustrates the overall structure, including the ovary, uterine tube and uterus. Diagrams show the process of the menstrual cycle and ovulation. Heavy gauge 3ml lamination with sealed edges and two metal eyelets for hanging makes chart highly durable. Write-on/wipe-off with dry erase marker (not included).

This new edition is a comprehensive and updated resource on antiphospholipid syndrome (APS), which is an autoimmune disorder. In APS, the body recognizes certain normal components of blood and/or cell membranes as foreign substances and produces antibodies (antiphospholipid antibodies) against them. APS is associated with recurrent clotting events (thrombosis) including premature stroke, repeated miscarriages, phlebitis, venous thrombosis, and pulmonary thromboembolism. It is also associated with low platelet or blood elements that prevent bleeding. Recently, however, even more disease states have been linked with APS, including premature heart attack, various cardiac valvular abnormalities, skin lesions, kidney disease, abnormal involuntary movement/chorea, diseases that mimic multiple sclerosis, and vascular diseases of the eye that can lead to visual loss and blindness. The International Congress on Antiphospholipid Antibodies, held every 3 years, is the venue where representatives from different disciplines gather to discuss the recent advances in APS. The conference intends to cover basic aspects of APS, such as pathogenesis, origins, genetics, intracellular and molecular events, the role of infections, as well as traditional and non-traditional clinical manifestations associated with antiphospholipid antibodies. The 15th Congress took place in September 2016. A novel aspect of the Congress was that multiple teams, chaired by Scientific Planning Committee members, used evidence-based literature reviews and expert discussions to answer specific pre-defined APS-related questions. These teams included points of view from experts in rheumatology, hematology, cardiovascular medicine, obstetrics, neurology, and immunology. The Scientific Planning Committee members also chaired the congress sessions and supervised completion of the reports that are the bases of the chapters of this book. In addition, there are two chapters included specifically written for APS patients. Much like the previous volume, dedicated to the 13th International Congress on Antiphospholipid Antibodies (April 2010), this up-to-date and comprehensive work gathers invaluable insights from a multidisciplinary team of world-renowned experts and represents the authoritative resource on causes, symptoms, diagnosis, and treatment of APS.

Hypertension: from basic research to clinical practice" contains a unique collection of selected chapters written by experts and enthusiasts engaged in research and treatment of hypertension, a condition that affects around a billion people in the world. The chapters describe fundamental researches at cellular and molecular levels to the science, and art of treatment of the condition in clinical practice. The topics included ranges from pathophysiology of hypertension, through monitoring of hypertension, to the treatment of hypertension in different patient categories. It contains essential background information as well as cutting edge research, and state of the art treatment alternatives in this broad field. From the beginners, and research students to the expert clinicians, and established scientists, everybody has something to learn from this book.

Meningitis and Encephalitis are associated with high rates of mortality and neurological sequelae. The differential diagnosis includes a wide spectrum of infectious and non-infectious etiologies, some requiring urgent therapy for survival. The current management challenges in patients with meningitis and encephalitis include a low sensitivity of meningeal signs, overutilization of unnecessary screening cranial imaging, delays in diagnosis of urgent treatable causes, a large proportion of unknown etiologies, low sensitivity of current microbiological techniques especially in the setting of previous antibiotic therapy, underutilization of available molecular diagnostic tests, and empiric antibiotic therapy and hospitalization for viral meningitis cases. Even though there are published guidelines, compliance with them is not optimal and physicians do not follow standardized algorithms in their empirical approach. As meningitis and encephalitis is associated with high rates of adverse clinical outcomes, prevention, when feasible is of upmost importance. Adherence to protocols to prevent health-care associated meningitis and ventriculitis are effective but compliance with them is not uniformly performed. This book seeks to improve outcomes for meningitis and encephalitis cases handled by physicians who may or may not be thoroughly trained for these challenges. The text introduces the current guidelines but also discusses the gaps that leave clinicians struggling to implement the most appropriate approaches for these particular neurological infections. Each chapter delivers the tools necessary to identify and adhere to the most appropriate diagnostic technique, management protocols, and prevention approach for each situation. All chapters conclude with discourse on future directions in research and quality improvement. Written by experts in infectious diseases, the book covers topics that are the most devastating, including healthcare-acquired infections, autoimmune encephalitis, and infections as they present in HIV patients. Meningitis and Encephalitis is a well-rounded resource for all medical professionals encountering these neurological syndromes, including infectious disease specialists, neurologists, primary care physicians, and immunologists.

This atlas gathers the most frequent imaging findings concerning alterations that cause infertility in both males and in females. Also, it discusses how the images should be analyzed and described, to serve as a guide for the physicians who request and perform these imaging tests. Infertility is a highly prevalent condition - about 10% of couples are infertile with males and females equally affected. This book offers professionals dealing with infertility, including endocrinologists, gynecologists and urologists, a useful guide to the diagnostic imaging tests that are essential in treating these patients. The Atlas of Imaging in Infertility is a valuable resource for physicians from different specialties managing cases of infertility.

This text provides a comprehensive, state of the art review of this field and will serve as a resource for urologists, colorectal surgeons, geriatricians, and gynecologists as well as researchers interested in neuromuscular phenomena in the pelvis. The book also reviews new data regarding risk factors for pelvic floor muscle dysfunction and profiles new minimally invasive surgical strategies for well known pelvic disease processes. Each chapter is chock full of data from landmark trials which have been published over the past few years and placed in context with respect to current management techniques for pelvic floor disorders. Written by experts in their field, Pelvic Floor Dysfunction and Pelvic Surgery in the Elderly: An Integrated Approach provides a concise yet comprehensive summary to help guide patient management.

This book uses global household data to examine the prevalence, trends and geographic variation of female genital mutilation (FGM) around the world. It also addresses the underlying legal and policy aspects as well as explores the medical consequences, both immediate and long term, for those undergoing the practice. The book analyses the position of victims of this gender-based violence both from the medical and legal perspective and adopts a largely practical approach to the study of the practices, offering a fresh thinking into one of the challenges in global health and the law. In addition, it offers some insights into how health professionals can approach this category of victims and how legal practitioners can obtain a good legal result for their clients before domestic and international forums. The book addresses fundamental issues such as state liability and defences in enforcement proceedings for actions or omission of state or non-state actors, and due diligence standard in international human rights law, the main gateways available for obtaining relief for the victims of FGM. This book goes beyond the traditional debate between zero tolerance and those who wish to see the practice medicalised and tolerated and favours an advocacy programme standing firmly in favour of the right of FGM victims. This book offers a unique perspective likely to assist victims and their representatives to secure a remedy against perpetrators and the state. As such this book will be of interest to medical professionals, national and international lawyers, academics and policymakers in the field of public health.

The main focus of this book is on ruptured uterus which is a potentially fatal complication during pregnancy. The risk factors and clinical presentation of ruptured uterus vary widely. This book gives an insight into the various possible causes and their presentation. This book aims to sensitize the practicing obstetricians about the need for high level of caution in the deceptive scenarios. The readers would be able to translate the clinical experience and shelf knowledge into every day practice. The cases with similar risks and background will be compiled together under one chapter and at the end of each chapter key points will be highlighted.

This book discusses 'how' to respectfully and responsibly include pregnant women in clinical research. In sharp contrast, the existing literature predominantly focuses on the reasons 'why' the inclusion of pregnant women in clinical research is necessary - viz., to develop effective treatments for women during pregnancy, to promote fetal safety, to reduce harm to women and fetuses from suboptimal care, and to allow access to the benefits of research participation. This book supports the shift to a new default position, whereby pregnant women are included in clinical research unless researchers argue convincingly for their exclusion. This shift raises many as yet unexplored ethical and policy questions about existing barriers to the equitable inclusion of pregnant women in research. This book is original in three key ways. First, it presents an unparalleled depth of analysis of the ethics of research with pregnant women, bringing together many of the key authors in this field as well as experts in research ethics and in vulnerability who have not previously applied their work to pregnant women. Second, it includes innovative theoretical work in ethics and disease specific case studies that highlight the current complexity and future challenges of research involving pregnant women. Third, the book brings together authors who argue both for and against including more pregnant women in formal clinical trials.

It is well-established, through extensive peer-reviewed published research, that physical activity and exercise training can impact the reproductive endocrine system of women. This ground-breaking, comprehensive title presents a range of unique insights into the opposite question: how the reproductive endocrine system of women affects their exercise ability. More precisely, the thematic question explored in this work is: if exercise affects reproductive hormones, conversely then could the reproductive hormones have physiological effects unrelated to reproduction that influence the capacity of women to exercise? In exploring this question, the goal is to better understand the unique physiology of women and whether female sex hormones might account for some of the variance in physiological performance between amenorrheic and eumenorrheic women, and within women across the age span as they experience menarche to menopause. Sex Hormones, Exercise and Women: Scientific and Clinical Aspects synthesizes the research by exploring the physiology and psychology behind these occurrences. This novel title will not only be of interest to researchers, exercise scientists, graduate students, and clinicians; it will also serve as a source of valuable information for female athletes and their trainers in the context of preparing for competitions.

This comprehensive reference uses an ecological perspective to sort out the complex mix of biological, psychological, social, and other factors influencing adolescent health as well as shaping professional responses to the needs of adolescents. Describing critical concerns at the global level and innovative strategies from selected countries, the book urges readers to develop and support practices and policies to enhance optimal youth development. Expert coverage centers on key areas: the global state of adolescent health and development, adolescent health issues and public health answers, making health systems more responsive to youth, and improving school health services. And bedrock themes such as social determinants of health, young people's right to health care, and health and gender disparities are discussed throughout these chapters. Included among the topics: * The epidemiology of adolescent health * Adolescent sexual health and sexuality education * Restorative justice and the mental wellbeing of adolescents * Critical issues in adolescent nutrition: needs and recommendations * Towards an adolescent competent workforce * Pairing children with health services: the changing role of school health services in the 21st century The International Handbook on Adolescent Health and Development is essential to medical schools, public schools, and college libraries; teaching faculty; graduate and post-graduate students in public health, medicine, social work, other behavioral sciences and health disciplines (e.g., nursing, allied heath); as well as practitioners interested in better orienting their services to the health needs of adolescents.