Practicing specialists in pathology, laboratory medicine, and obstetrics comprehensively summarize the latest scientific findings and their experiences in the use and interpretation of laboratory testing in patients who are pregnant or experiencing recurrent pregnancy loss. Topics of interest include the effects of normal physiological changes on test results, test selection for diagnosis, changes in reference ranges, monitoring the pregnant patient, new technologies, and the limitations of laboratory testing. The authors not only clearly explain currently used test methods and technologies for the nontechnical reader, but also provide comprehensive details for laboratory professionals. The comprehensive appendix that compiles published normal reference ranges by first, second, and third trimester consttitutes an excellent resource for professionals caring for pregnant women.

This book is an accessible guide to caring for survivors of sexual and gender-based violence (SGBV). Sexual violence is broadly defined in order to include sexual assault, but also often forgotten subjects such as female genital cutting, sex trafficking, and military sexual violence. The average practitioner, gynecologist or otherwise, will undoubtedly encounter a victim of some sexual violence during their time in practice and this guide is designed to answer all questions on how to approach, treat, and understand a survivor of sexual violence. Written by a multidisciplinary team of medical, psychological, and legal experts, the book is organized into four sections. The first section begins with a scholarly analysis of trauma and how to discuss that trauma with patients. The second section covers types of violence and populations at risk, including intimate partner violence, sex trafficking, and LGBTQ considerations. The third section provides critical focus on the examination procedure, providing strategies for speaking to survivors and conducting a sensitive medical examination. Within each of these chapters, the reader will find experts sharing their tips, best practices, and understandings of exactly how trauma affects care. The final section covers medicolegal legal issues, providing a basic introduction to general legal processes regarding sexual violence matters in the US in order to serve as a resource for any practitioner presented with legal questions by a patient. This book gives a comprehensive overview of clinical care for survivors of SGBV. The clinical focus of this book goes beyond emergency room and crisis intervention protocol described in other books and makes it an ideal guide for all general health practitioners treating this population.

As research in neuroscience increasingly points to the unparalleled influence of the first 1000 days of life from conception to two years of age in determining the baby's life trajectory, the need for high-quality early parenting education delivered by knowledgeable and dedicated professionals becomes ever more apparent. This book describes the global aims of early parenting education. It identifies the key areas that research suggests are important: building a relationship with the unborn and newborn baby; preparing for labour and birth; supporting parents' mental health; protecting the couple relationship across the transition to parenthood; and education for special groups such as same-sex couples, women with fear of birth, prisoners, military wives and parents from black and minority ethnic backgrounds. All practitioners providing early parenting programmes - midwives, health visitors, family link workers, children's centre staff and voluntary sector teachers - will gain new ideas for their practice in this book. Students taking midwifery and early childhood courses will find much to support their studies. Ultimately, the book provides inspiration for all those who are committed to the role of parenting education in reducing social inequalities.

The National Institute of Health interrupted their huge HRT study in July 2002 when they found that the drug Prempro, a combination of estrogen and progestin, had detrimental health effects. The women who took the drug exhibited an increased risk for breast cancer, heart disease, and stroke.
Women can lose up to 20% of their bone mass in the first seven years after menopause. Post-menopausal women are twice as likely as men to die of a heart attack. Natural estrogen is the answer.
In this book the authors provide a healthy and natural alternative to HRT. They not only provide nutritious, healthy and delicious recipes; they also explain why phytoestrogens -- plant estrogens -- can alleviate the symptoms of menopause and promote a woman's health. THE NATURAL ESTROGEN DIET AND RECIPE BOOK is the answer to women who are seeking to retain their health through and after menopause in a completely safe, effective and natural way. It also shows women of any age how to make healthy food a permanent part of their lives.

A discussion of all the key issues in the use of human pluripotent stem cells for treating degenerative diseases or for replacing tissues lost from trauma. On the practical side, the topics range from the problems of deriving human embryonic stem cells and driving their differentiation along specific lineages, regulating their development into mature cells, and bringing stem cell therapy to clinical trials. Regulatory issues are addressed in discussions of the ethical debate surrounding the derivation of human embryonic stem cells and the current policies governing their use in the United States and abroad, including the rules and conditions regulating federal funding and questions of intellectual property.

Cervical laminoplasty for the treatment of ossification of the posterior longitudinal ligament was developed and refined in Japan during the 1970s. Since that time, various cervical laminoplasty techniques have been further analyzed and modified, and have proven to be clinically successful. Until now cervical laminoplasty has been practiced primarily in Japan, and surgeons outside Japan had only limited access to the detailed English literature needed to make full use of the procedures. This book fills that gap in English information and provides a detailed, up-to-date guide to performing safe and effective cervical laminoplasty. Drawing on the latest knowledge from Japan, the book covers the history of cervical laminoplasty, surgical anatomy, basic procedures, modified procedures, possible complications, and perspectives on the future of expansive laminoplasty. This volume by leaders in the field is an excellent guide for all surgeons interested in laminoplasty.

This immensely practical handbook provides the busy clinician with a self-contained account of the diagnosis and management of ectopic pregnancy. Such pregnancies, which develop outside the uterine cavity, are an increasingly common occurrence. The focus throughout is on diagnosis and management issues, and the author provides rapid solutions to the most difficult problems posed by ectopic pregnancy. The text is fully supported by numerous and helpful ultrasound images, line diagrams illustrating surgical techniques, and by highlighted summaries of key facts and decision trees.

Comprehensive Video Atlas of Laparoscopic Surgery in Infertility and Gynecology is an extensive video atlas featuring 74 videos which provide instruction on a wide range of laparoscopic procedures. The video atlas is divided into twelve sections, beginning with a general guide to laparoscopic surgery which includes instructions for setting up the operating room. Subsequent sections include videos on adnexal surgery, endometriosis, infertility, myomectomy, total laparoscopic hysterectomy (TLH), pelvic floor repair, and ectopic pregnancy. Comprehensive Video Atlas of Laparoscopic Surgery in Infertility and Gynecology includes nearly ten hours of video across eight DVDs, with later videos covering special surgery topics such as microsurgery and robotic surgery, and the emerging field of cosmetic gynaecology, making this an ideal resource for gynaecologic laparoscopic surgeons. Key Points Extensive video atlas providing visual instruction on a wide range of laparoscopic procedures Includes guidance on setting up the operation room Special video sections on cosmetic, robotic and microsurgery procedures 74 videos, 8 DVDs, duration 9 hours 36 minutes

Ultrasound and Endoscopic Surgery in Obstetrics and Gynaecology focuses and highlights the pivotal role these two techniques play in modern obstetrics and gynaecology. Taking a problem-orientated approach, the book includes sections on menorrhagia, postmenopausal bleeding, endometrial malignancy, urogynaecology, ovarian masses, endometriosis, early pregnancy complications and infertility. A multi-contributed book with short, practical chapters, the book is well illustrated with more than 60 colour illustrations. Ultrasound and Endoscopic Surgery in Obstetrics and Gynaecology uniquely combines these two fields to demonstrate management of common gynaecological conditions based on accurate ultrasound diagnosis and minimal access treatment. An authoritative practical 'how-to' guide, this book will be invaluable for practitioners to learn and perfect both techniques and use them to their maximum potential.

Within 10 chapters this book addresses the whole gamut of questions that may arise in the context of pregnancy resulting from assisted reproduction. Incidence of abortion, extrauterine pregnancy or chromosomal abnormalities, pregnancy complications, problems regarding mode of delivery and the health status of children at birth are covered as well as the further development of the children and the social structure of the families. Topics such as follow-up of families in lesbian relationships and following gamete donations are also discussed.

For medical students, generalists, and specialists alike, Netter's Obstetrics & Gynecology, 4th Edition, provides superbly illustrated, up-to-date information on the conditions and problems most often encountered in OB/GYN practice. Classic Netter images are paired with concise, evidence-based descriptions of common diseases, conditions, diagnostics, treatments, and protocols. Large, clear illustrations and short, to-the-point text provide quick, authoritative access to expert medical thinking-perfect for gaining knowledge of this complex field, for everyday clinical practice, or for staff and patient education. Features concise, exquisitely illustrated coverage of Anatomy and Embryology, Gynecology and Women's Health, and Obstetrics. Contains more than 300 exquisite Netter images, as well as new, recent paintings by Carlos Machado, that provide a quick and memorable overview of each disease or condition. Includes eleven new chapters, including Sexuality and Gender Dysphoria, Alcohol Abuse in Women, Anal Incontinence, Cardiovascular Disease in Women, Genitourinary Syndrome of Menopause, Hereditary Cancer Syndromes, External Cephalic Version, and more. An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.

Experimental and clinical researchers from a wide range of disciplines present a wealth of fresh scientific information on the biochemistry, molecular biology, pharmacology, and clinical activity of SERMs. The basic science chapters of the book focus-with an eye to the development of the ideal SERM-on the complex mechanisms of estrogen action, including ligand-dependent conformational changes in alpha and beta, and the recruitment of co-activators and co-repressors which modulate the estrogen receptor transcriptional activity and contribute to its crosstalk with growth factor signaling. The clinical presentation reviews the data accumulated on currently available SERMs, primarily tamoxifen and raloxifene, in cancer treatment and prevention, as well as their effects on the reproductive, vascular, skeletal, and central nervous systems. A tentative approach to menopause-related health issues is also provided for women with and without a previous diagnosis of localized breast cancer.

Updated, revised, and reorganized, the Second Editions in the Clinical Sciences reflect the format of the USMLE Step 2. Each volume systematically presents the core information of a single segment of the medical curriculum, from Family Medicine to Psychiatry. You will also learn time-honored tricks of the trade, as well as the latest advances in clinical medicine: new diagnostic tools, new therapeutic interventions, and new pharmacologic options.

Epigenetics is the study of how certain genes are activated without modification at the DNA sequence level, resulting in genetically similar individuals having different clinical outcomes. As contemporary medicine increasingly aims to personalize the medical approach to a patient's genetic profile, the factors that can affect which genes are expressed also increase in importance and relevance to the clinician. This text from experts will give the clinician in Reproductive Medicine a reliable grounding in current thinking and research on this fast-moving topic, with many clinical implications.

The female patient with chronic kidney disease often requires care that differs from the male patient. Particularly in the pregnant patient, a specialized body of knowledge is required to provide optimal care. This book focuses on such issues encountered during pregnancy including physiology and pathophysiology of pregnancy, hypertension, preeclampsia, various electrolyte disorders, nephrolithiasis, pharmacological management in the pregnant patient with kidney disease and during breastfeeding, acute kidney and chronic kidney disease, dialysis of the pregnant patient, lupus nephritis, thrombotic microangiopathy, glomerular disease management, use of renal biopsy during pregnancy, care of the female transplant patient, contraceptive counseling and postpartum care, various endocrine disorders, and bone disease in the female patient with chronic kidney disease. This book features the latest evidence and clinical approaches for the beginner or for the experienced practitioners who care for pregnant woman or even for those who require expertise in women's health. Written by experts in the field, Obstetric and Gynecologic Nephrology: Women's Health Issues in the Patient with Kidney Disease is a valuable resource for clinicians and practitioners involved in the care and treatment of obstetric and gynecologic patients afflicted with kidney disease.

Is women's destiny rooted in their biology? Since the end of the eighteenth century the science of gynecology has legitimized the view that women are "naturally" fitted for activities in the private sphere of the family. This book argues that the definition of femininity as propounded by gynecological science is a cultural product of a wider, more political context. Providing a unique account of gynecology in practice, it shifts the historical focus from the use to the production of ideas about "women's nature." Dr. Moscucci traces the origins of gynecology to the emergence of a predictable "science of man" in the late eighteenth century and charts the ideological, professional and institutional development of the subject up to the foundation of the Royal College of Obstetricians and Gynaecologists in 1929. Case-studies of Victorian gynecological practice at two London hospitals illustrate the changing pattern of institutional gynecology, affording valuable insight into the relationship between gynecologists and patients. The book also stresses the equal importance of class and gender ideology in shaping medical views about women's diseases and their treatment.

Cancer and Pregnancy covers the clinical challenges to diagnosing and treating malignancies in the pregnant patient; however, the book also shows how an understanding of the common features of both processes (rapid cell proliferation) may lead to novel anti-cancer treatment options. The book should be read by obstetricians and gynaecologists, clinical oncologists, reproduction specialists, and those involved in investigation of development, biology, toxicology, immunology, as well as cancer research.

With mesh surgery for prolapse sometimes proving problematic, there has been a resurgence of professional medical interest in more traditional methods for the management of prolapse and of stress urinary incontinence. This concise guide to the practical aspects of pessary use will be of interest to all gynecologists involved in the clinical management of the patient with these problems. Contents: Historical review * Pessaries for pelvic organ prolapse * Incontinence pessaries * Pessary fitting * Pessary care * Outcomes of pessary use * Current clinical studies on vaginal pessaries Cover image of vaginal pessaries (c) 2019 Rick Hicaro, Jr., Chicago, IL 60647, USA

The alternation between urine retention and discharge several times daily from a nappy to the cessation ofall vital functions only becomes the subject baby's first wet of greater attention if the harmony of the structure and function of the bladder is disturbed. Functional disturbances of the lower urinary tract are not only of great socio-economic importance, but are also a considerable personal burden for the patient. Hence urinary incontinence is rightly classified as a severelydisabling illness (Hauri 1985). Opinions still differ regarding the morphological basis ofurinary continence.The Terminologia Anatomica (1998) defines a musculus sphincter urethrae internus (in- ternal urethral sphincter) and a musculus sphincter urethrae externus (external ure- thral sphincter),which in the older nomenclature were known as musculus sphincter vesicae and musculussphincterurethrae,respectively.The internal urethral sphincter isascribed apurelyinvoluntaryandthe externalurethralsphincterapurelyvoluntary innervation. The significance of the musculature of the pelvic floor for maintaining urinarycontinence has notyetbeen ascertained. Duringnumerous urologicaloperations (forinstancetransurethralresectionofthe prostate and bladder neck incisions), the only involuntarily innervated sphincter at the collum vesicae,the internalurethralsphincter,is partiallyorcompletelydestroyed (Fig. 27C,D).All the patients remain continent as long as the externalurethral sphinc- ter remains intact.Howcan apurelyvoluntarilyinnervated sphincterlikethe external urethral sphincter ensureconstant continence in such cases? Improving the continence rate after radical surgery is a key topic of urological research. The incontinence rate after radical prostatectomy is still between 8.1% (third-degree incontinence) and41.4% (first- to second-degree incontinence; Rudyet al. 1984; Igel et a1.1987; Schroderand Ouden 1992).

The aim of this book is to provide a straightforward summary of the knowledge required for examinations in specialist Obstetrics and Gynaecology. Part Two of the examination for Membership of the Royal College of Obstetricians and Gynaecologists would be a good example. The volume is intended as a companion to the highly successful Basic Sciences for Obstetrics and Gynaecology which covers the knowledge required for preliminary examinations. Increasingly, examinations of all types are based on multiple choice questions (MCQ) or structured answer questions (SAQ). No apology is made for the fact that the present book addresses the sort of "fact" which lends itself to testing by this approach. Thus, there is little discussion of speculative or contentious areas, no account of present or future research, and no references. Numerous excellent books are available which cover these topics in a much fuller and more discursive manner, and the present volume does not seek to emulate them. Even the most apparently immutable facts are subject to periodic revision. We have attempted to present the "state-of-the-a.rt": most of the material is generally if not universally accepted. A particular problem arises with numerical information. Frequencies of diseases, frequency of clinical findings, efficiency of diagnostic tests and therapies, have almost always been the subject of numerous different studies, each of which yields somewhat different results.

Risk, Age and Pregnancy provides an in-depth case study of the operation of a prenatal genetic screening and testing system. The methodology integrates observational, qualitative interview and survey data. The perspectives of pregnant women, hospital doctors and midwives are explored in depth, as is the communication between women and the hospital doctors who advise them. The book offers insights which are relevant to those concerned with the rapidly growing field of genetic risk management.

approaches to the experimental problems that still face us in understanding this most fascinating of organs. Too many people contributed to the completion of this volume to allow acknowledg ment of all the individual efforts, but we particularly thank the reviewers whose input into the editorial process was invaluable and the authors of these chapters who revised their text, sometimes more than once, to bring it to the high standards set by the Editors. The Com mittee gratefully acknowledges the support ofVysis, Inc. , in the publication of a color figure in Chapter 19, by S. Weber-Hall and Trevor Dale. Finally, we wish to express our heartfelt appreciation to Margot Ip and Bonnie Asch, who worked long and hard to bring this volume to fruition. Margaret C. Neville for the Committee on Mammary Gland Biology Preface One of the most exciting and beneficial developments in research on mammary gland biology and breast cancer has been the influx of increased funding to support this work. This influx, which has been due primarily to the tireless efforts of breast cancer activists to gamer addi tional money from various federal and state sources, has led to a rapid expansion of research efforts by attracting numerous new investigators into the field. These new investigators include students, postdoctoral fellows, and scientists from other fields.

Management Options in Breast Cancer is the only comprehensive resource devoted to exploring the systematic approach to breast cancer diagnosis, surgery, and postoperative care. This guide is an ideal tool for oncologists, pathologists, radiologists, and gynecologists seeking alternative management options for breast cancer. In addition, trainees will find this text a valuable reference for learning the basic principles and clinical guidelines of the field. Key features in this stand-alone text: an international review of the management options in the field of breast cancer clinical practice case-based examples designed to aid in optimal clinician decision-making two chapters devoted to rarely-explored topics: male breast cancer and geriatric breast cancer

This book will enable practicing physicians and trainees to learn, in a clinically relevant and intellectually stimulating way, guidelines for appropriate ordering of imaging exams. The new edition provides more than 460 clinical case scenarios, organized into subspecialty modules (breast, cardiac, thoracic, gastrointestinal, urologic, women's, pediatric, vascular, musculoskeletal, and neurologic imaging). Each scenario is presented as a quiz in which the reader is invited to select the best option from various imaging modalities. All choices are given ratings of appropriateness and is consistent with the American College of Radiology (ACR) Appropriateness Criteria. Furthermore, a brief solution to each case is included. Finally, over 500 radiologic images are included each associated with a clinical case to illustrate the diagnostic capabilities of the imaging exam. This second edition incorporates new content and revisions to remain consistent with the updated ACR Appropriateness Criteria since the original publication in 2012. It will be an ideal tool both for self-study and for quantitative evaluation of students' knowledge.