Now in its second edition, this book remains a vital reference manual for those pathologists whose work involves them in the interpretation of endometrial biopsies. A full account is given of the appearances of the endometrium during the menstrual cycle, of the effects of hormones, the changes induced by steroid contraceptives and intrauterine devices, of functional disorders and of inflammatory disease. Particular attention is given to the various forms of hyperplasia and neoplasia, with special emphasis being placed upon the differential diagnosis of these conditions. Other chapters deal with sampling techniques, the anatomy and histology of the normal endometrium, descriptions of the tissue in normal and abnormal pregnancy, and gestational trophoblastic disease. This fully revised second edition reflects the fact that numerous new entities have been defined, the classification of many disease states has altered and new understanding of many endometrial diseases has been gained. This edition also discusses the changing pattern of endometrial biopsies resulting from modified clinical practice. Biopsy Pathology of the Endometrium provides the pathologist and gynaecologist with a highly illustrated and practical manual whose high quality photomicrographs will be an indispensable reference during the interpretation of endometrial biopsies.

The first work of its kind, The History of Medications for Women: Materia medica woman is a richly detailed, far-ranging illustrated history of medications for women in all the great cultures and civilizations, from ancient times to the present. Compiled by an acclaimed author of medical history literature, this is the only book that extends from the earliest uses of ergometrine, lettuce, and mummy medicine, through the history of women's medications in ancient Assyria and Egypt, and into the 16th through 20th centuries.

With the main sections organized by origin and timeline, the book contains lists of medications used by women from earliest times to the present accompanied by historically-based text. The author includes botanical, chemical, pharmacalogical, and therapeutic details where appropriate, as well as extensive quotations from both contemporary and old, rare books. The text is complemented with the history of obstetrics and gynecology, along with short biographies and illustrations. Additionally, the author presents a unique fund of hard-to-find information in sections devoted to topics such as anesthesia and analgesia, antiseptics, antibiotics and chemotherapy, blood transfusion and Rhesus disease, eclampsia, family planning, menopause, and uterine stimulants. Interesting and thought-provoking, The History of Medications for Women will not only provide an enjoyable read, but will allow you to appreciate the past and look at the future with a new perspective.

This thoroughly revised and updated reference addresses the drugs and chemicals causing malformations and congenital anomalies in the human fetus-comprehensively reviewing experimental studies in animals and clinical data on human development, primarily in the organogenesis period. Addressing current public health concerns over teratogens, Chemically Induced Birth Defects, Third Edition covers and condenses the 2500 new publications on developmental toxicology that appear every year. Provides comprehensive identification of teratogens by chemical, generic, and trade names. Chemically Induced Birth Defects, Third Edition -discusses the interrelation of over 4100 chemicals in current use, still in the experimental stage, or now obsolete -covers recently available drugs, such as misoprostol and fluconazole -utilizes the latest Good Laboratory Practices-conducted studies to evaluate specific agents -investigates up-to-the-minute impairments of maternal homeostasis that may lead to teratogenesis -surveys chemicals by use, distinguishing medicinals from industrial chemicals -elucidates recent research on chemicals linked to endocrine disruption -and more! Containing over 10,000 citations from the literature, Chemically Induced Birth Defects, Third Edition deserves a place on the bookshelves of all toxicologists, teratologists, pediatricians, obstetricians, gynecologists, environmentalists, biochemists, oncologists, pharmacologists, endocrinologists, and upper-level undergraduate, graduate, and medical school students in these disciplines.

At a time when major universities are moving all scientific journals published before 1975 to remote locations and authors are instructed to cite only articles published in the last 20 years, when medical information is captured in the media in sound bites of 30 seconds or less, History of Obstetrics and Gynaecology is an indispensable addition to your personal library. The book recounts the events and changes that have taken place over many centuries in society: changes in scientific knowledge and the way it is communicated, changes in technology, and changes in the lives and times of those who have dedicated their efforts to the health of women and their progeny.

Covering developments in seemingly unrelated fields, the book illustrates how they were vital to advances in gynaecology and obstetrics. This multi-faceted approach, chronological tables, and reviews of related subjects and technologies, provides a far richer and more comprehensive treatment than would be possible if the authors had written from a century-by-century perspective. With narrative that engages and draws you along page after page, History of Obstetrics and Gynaecology puts the achievements of the last millennium in perspective.

Reflecting recent changes to the exam, MRCOG Part 2: 500 SBAs and EMQs, Second Edition has been completely updated to include questions and answers in the new SBA format. With over 50% new content, MRCOG Part 2: 500 SBAs and EMQs offers the most up-to-date and comprehensive set of practice questions for trainees preparing for the MRCOG Part 2 exam. Chapters are mapped to the syllabus to deliver structured revision in all the key topics tested in the exam. Featuring a wealth of practice questions and fully descriptive answers, this book provides the essential revision text to maximise chances of exam success. Key Points 500 questions, comprising 250 SBAs and 250 EMQs, reflecting the breadth of topics encountered in the actual exam Questions structured around MRCOG syllabus core modules, ensuring complete coverage for the exam Answers feature concise descriptions to consolidate knowledge and understanding Extensive evidence-based referencing to relate theory to clinical practice Visually-enhanced answers to improve understanding of key concepts  

Ultrasound is the main diagnostic tool in the prenatal detection of congenital abnormalities. The Fetal Medicine Foundation has recognized the importance of this tool by setting up a program of training and certification to help establish high standards of scanning on an international scale. Diagnosis of Fetal Abnormalities: The 18-23-Week Scan provides the basis of learning for the theoretical component of this program. The book is a complete, authoritative clinician's textbook on using ultrasound in the prenatal detection of congenital abnormalities. It summarizes the prevalence, etiology, prenatal sonographic features and prognosis for both common and rare fetal abnormalities.

Type 1 diabetes is a serious and common disease, afflicting one per 200 of the population worldwide. It is widely believed to cause harmful physical maldevelopment--congenital malformations--and other consequences in the unborn children of women with the disease. This book considers the history of the disease in pregnant women and this belief that it causes anomalies since the time of the discovery of insulin in 1921, and presents a profound and critical appraisal of the subject of its supposed prenatal harmfulness.

In lebensbedrohlichen Notfallsituationen ist sofortige Hilfe für die Patientin essenziell, auch ein ungeborenes Kind bedarf der besonderen Aufmerksamkeit. Ebenso wichtig ist es, medizinischen Komplikationen zielsicher zu begegnen. Der klar und übersichtlich strukturierte Leidfaden liefert Informations- und Entscheidungshilfen, die eine rasche und adäquate Diagnostik und Therapie ermöglichen. Zudem werden die Möglichkeiten der modernen gynäkologischen und geburtshilflichen Analgesie aufgezeigt. Die 3. Auflage wurde sorgfältig aktualisiert.

The advent of hormonal infertility treatments and in vitro fertilization techniques have led to a sharp increase in the number of quadruplet and higher-order conceptions in recent years. Improved neonatal care and nutrition have meant that many more of these babies survive. Yet it appears that very little research has been done into the lives of such children and the psychodevelopmental consequences of their multiple status. In this book, Marie M. Clay brings together what is known from historical records and reports in the medical, psychological, and popular press. She points to the contribution that research studies on higher multiple sets could make to our understanding of genetic-environmental interactions and gives valuable methodological advice for those wishing to initiate such a study. Changes in social practices and medical knowledge are highlighted, various aspects of pregnancy and birth are discussed, and the practical and emotional problems faced by families of multiple sets are sensitively described. Appended to the book are an illustrated 'Catalog' of quadruplet case reports gleaned from the literature, including birth details and postnatal histories, plus a directory of multiple birth associations, support groups, and study centers around the world.

This is the sixth edition of a popular, highly readable primer in obstetrics and gynaecology. It has been thoroughly updated and aligns with the undergraduate curriculum in O&G devised by the Royal College of Obstetrics and Gynaecology. Highly illustrated throughout Essential information points at the end of chapters Case histories Practical procedures boxes Alert (warnings or advice) and tick (guidance or definitions) boxes throughout Over 100 self-assessment MCQs Appendices: Principles of Perioperative Care; Governance, Audit and Research Reflects the national undergraduate curriculum in obstetrics and gynaecology in the UK and Australia More information on: Fetal development Screening for fetal anomaly: non-invasive prenatal testing Placenta accreta Infections acquired in pregnancy: Zika, Rubella Non-invasive prenatal testin Fetal Doppler examination, e.g. middle cerebral artery, ductus venosus Management of preterm labour: oxytocin antagonists Induction of labour: components of Bishop score Ectopic pregnancy: Caesarean scar ectopic, cornual ectopic Emergency contraception: ulipristal acetate Sterilization: salpingectomy Genital tract infections: role of sexual health clinic, contact tracing Cervix: update on HPV screening and vaccination Ovary: update FIGO staging of ovarian carcinoma; "risk reducing surgery" for ovarian cancer WHO surgical safety checklist added to Appendix A. New self-assessment OSCE questions

1. Prologue.- 2. Is Estrogen A Cellular Signal for Female Genital Tract Epithelium?.- 3. Reciprocal Tissue Interactions in Morphogenesis and Hormonal Responsiveness of the Female Reproductive Tract.- 4. Qualitative and Quantitative Morphology of Induction in Endometrial Epithelium.- 5. Interactions of Estrogens, Protooncogenes and Growth Factors.- 6. Expression of Metallothionein Genes in Preimplantation Embryos, Decidua and Placentae.- 7. Uterine Preparation for Blastocyst Attachment.- 8. Uterine Extracellular Matrix Remodeling in Pregnancy.- 9. Glycoprotein Expression and Function in Embryo-Uterine Interactions.- 10. Uterine-Conceptus Interactions During the Peri-implantation Period.- 11. Endocrine Functions of the Rodent Placenta: Placental Lactogens.- 12. The Origin and Role of Cytokines Determining Success and Failure in the Post-implantation Period.- 13. Epilogue.- Poster Presentations.- Contributors.

This collection examines enduring and topical questions in sexual and reproductive health in a range of contemporary Asian cultures. Beliefs and practices surrounding conception, pregnancy, birth, and confinement are studies in culturally specific contexts in Japan, Taiwan, the Philippines, Thailand, Laos, Cambodia, and Indonesia. Important and widely applicable health issues are also addressed, including the perception and management of HIV/AIDS, experiences of menopause and the interaction of cosmopolitan ("western'') medicine with traditional healthcare.

This highly regarded atlas has been revised and updated, with 60 new colour illustrations highlighting key clinical points.

Children With Prenatal Drug Exposure examines new medical approaches for predicting the developmental progress of children who have been exposed to drugs in utero. This book outlines effective methods for intervention and assessment and indicates future directions for investigation. It provides practical and up-to-date information on treatments and research development, while it encourages practitioners to come to their own conclusions through careful documentation and analysis of each case. Children With Prenatal Drug Exposure cuts across many disciplines to provide the reader with a vivid analysis of the complexities and challenges surrounding health care of children who have been prenatally exposed to drugs. This guidebook explores the controversies over treatment and therapy options and the ethics of care. It advocates positive outcome intervention methods that promote the health interests of both mother and unborn child whenever possible, with an emphasis on clinical efforts geared to change maternal behavior.Practical and comprehensive, Children With Prenatal Drug Exposure explores a full range of provoking topics, including: neurological effects and sensory motor delays caused by cocaine exposure foster care and its impact on motor development adolescent pregnancy and the complications of prenatal substance abuse ethical dilemmas multidimensional measurement systems and longitudinal research The book's authors believe that in order to meet the needs of children who have been prenatally exposed to drugs, care providers must know the limitations associated with the process and methodology of assessment and learn to address the shortcomings of evaluation. With this in mind, this book aims to equip psychologists, physical and occupational therapists, researchers, and physicians with the know-how they require for optimizing their health care services and contributing valuable research that the field so urgently needs.

The only text to focus specifically on advanced health assessment/management of women This authoritative text for busy clinicians, advanced practice students, and faculty delivers essential content focused on improving the quality of healthcare provided to women/persons with a vagina across the lifespan. Brimming with new and updated content, the fifth edition reflects the most current evidence-based clinical practice guidelines available. It includes 14 new chapters written by experts in their field and the addition of disease management content, especially medications. Chapters are enhanced with management/pharmacology summary charts and case studies with discussion questions. The use of two colors improves readability, and amplified Instructor Resources include key statistics/epidemiology, learning objectives, suggested student activities and self-assessment questions, and UAB videos. Using a clear, concise outline format, this user-friendly text delivers quick, comprehensive information regarding the health assessment and management of women/persons with a vagina. It defines the role, skills, and scope of practice of different health providers and illuminates a variety of assessment skills, techniques, and procedures used by advanced practice clinicians in everyday practice. Sample assessment forms are integrated throughout along with numerous educational handouts for patients. Discussion of techniques includes a comprehensive list of requisite equipment and information on patient prep and recommended follow-up. Boxes, tables, and figures throughout reinforce key information. Purchase includes access to eBook for use on most mobile devices or computers. New to the Fifth Edition: Fourteen new chapters Telehealth in women's health Vaginal health and vaginal microscopy Mental health screening Preconception care Complementary and alternative medical therapies Adolescent health Lactation assessment and management Female veterans Male sexual and reproductive health Amenorrhea PMS/PMDD Sexual health and related problems Human trafficking The contraceptive consult Expanded breast health including breastfeeding Transgender care Updates on screening instruments Best-practice apps Case studies Management/treatment summaries Enhanced instructor package including key statistics/epidemiology, learning objectives, student activities, and self-assessment questions Two-color printing to improve readability Step-by-step videos of five office gynecology simulations from UAB Key Features: Delivered in outline, bulleted format for speedy reference Reflects the most current evidence-based clinical practice guidelines Offers easy-to-follow, step-by-step coverage of procedures Addresses treatment/management of multiple conditions Includes detailed illustrations

Placental Toxicology examines placental transfer and toxicology of drugs and environmental agents to placenta, as well as to fetus. For the first time in a single volume, placental and fetal consequences of exposure of pregnant women to drugs, environmental chemicals, and infections, such as HIV, are discussed. Topics include:
The art of in vitro perfusion of human placenta
Abuse of alcohol, nicotine, morphine, and cocaine during pregnancy, their placental transfer and fetal growth retardation
Placental transfer and fetal toxicities of environmental insecticides
Placental hormones and fetal well-being
Placental transfer of HIV and treatment of pregnant women with anti-HIV drugs

Providing a comprehensive review of the interactions between exercise and human reproduction, this unique text focuses on both the positive and negative consequences of sport and physical activity on male and female fertility and infertility and the biological mechanisms and processes behind them. Beginning with a review of the structure and function of the male and female reproductive systems as well as fertilization and gestation, the discussion then turns to the physiology and endocrinology of sport and exercise, which is further elaborated in subsequent chapters on the impact of physical activity, hormonal changes, pathologies, and consequences of drug use for active men and women. Additional chapters address related topics, such as the impact of sport on young athletes and developing reproductive potential, physical activity and pregnancy, the use of oral contraceptives in athletes, oxidative stress, and the impact of nutritional deficiencies on athletes' fertility, with a final chapter providing recommendations and therapeutic guidelines for exercise-related reproductive disorders. Covering everything from the fundamental principles of sports physiology and human reproductive potential to the interaction between physical exercise and the endocrinology of the reproductive system, Exercise and Human Reproduction is an authoritative resource for helping clinicians understand how the reproductive system adapts to activity and exercise and offers strategies to avoid potential harm to human reproduction.

In celebration of its 20th anniversary, a thoroughly revised and expanded edition of the leading book on fertility and women's reproductive health. Since the publication of Taking Charge of your Fertility two decades ago, Toni Weschler has taught a whole new generation of women how to become pregnant, avoid pregnancy naturally and gain better control of their gynecological and sexual health by taking just a couple minutes a day using the proven Fertility Awareness Method. Now, this 20th Anniversary Edition has been thoroughly revised and fully updated with: the latest medical advances in assisted reproductive technologies (ART) more in-depth coverage of women's gynecological and sexual health new illustrations, photographs, and an expanded color insert new sample charts an expanded appendix Six new chapters including: Three Prevalent Conditions--Endometriosis, Ovarian Cysts and PCOS Natural Ways to Balance Your Hormones Preserving Your Future Fertility Miscarriages Idiopathic Infertility Causes of Unusual Bleeding Clear and comprehensive, yet warm and approachable, Taking Charge of Your Fertility is one of the most universally lauded health books on the market today. It is an essential reference for every woman of reproductive age.

Reproductive health care professionals in fields such as Obstetrics and Gynecology, Family Medicine, and Pediatrics face difficult ethical issues because they work at the crossroads of patient decision-making, scientific advancement, political controversy, legal regulation, and profound moral considerations. The dilemmas these professionals face expose big-picture bioethics questions of interest to everyone. Yet for clinicians striving to deliver excellent patient care, the ethical questions that make daily practice challenging can be just as nuanced. This volume presents a carefully curated compilation of essays written by leading experts in the fields of medicine, ethics, and law, who address key issues at the forefront of reproductive ethics. It is organized into three main sections: I. Contraception and Abortion Ethics - Preventing Pregnancy and Birth, II. Assisted Reproduction Ethics - Initiating Pregnancy, and III. Obstetric Ethics - Managing Pregnancy and Delivery. Each section begins with a short introduction by the editors providing an overview of the area and contextualizing the essays that follow. This volume's primary aim is to be useful to practicing clinicians, students, and trainees by providing short and practical essays covering urgent topics-from race, religion and abortion, to legal liability, violations of confidentiality and maternal choices that risk future children's health. This collection provides clinicians at all levels of training with frameworks they need to approach the intimate and high-stakes encounters central to their profession.

This book deals with the management of labour, guiding the readers to recognize problems by keen monitoring, based on anatomical and physiological understanding of labour. In this era of technology, this book revives the fading art of identification of clinical signs and symptoms. The chapters are well-structured, covering different aspects from suspicion to identification of the problems by recognizing subtle warning signals by the fetus and the uterus. Operative deliveries and common obstetric emergencies with their appropriate management are also covered. It provides practical points to prevent, anticipate, recognize, and manage problems during labour. Key Features Helps to identify clinical signs and symptoms that infuses the reader with confidence to identify and manage abnormal situations during labour and childbirth through the feel of their fingers and awakened understanding. A must have book for all postgraduate trainees and practitioners of obstetrics, eager to learn the fundamentals of labour management. Features illustrated cases helpful in learning management of normal labour and pick abnormal labour, at the earliest possible deviation from normalcy.