This book is a guide to labour and delivery management for trainees in obstetrics and gynaecology, and midwives. Divided into three sections, the text begins with detailed discussion on labour, from preparation before labour and delivery, through the different stages of labour, to postpartum care. The next section covers caesarean delivery, and the third, 'special labour' which explains labour complications, twins, prelabour rupture of membranes, and more. The book is authored by recognised experts from the USA and Italy, and is based on evidence from randomised controlled trials (RCTs). Clinical photographs, diagrams and tables further enhance learning. Key points Guide to labour and delivery management for trainees in obstetrics and gynaecology, and midwives Text based on evidence from randomised controlled trials (RCTs) Recognised author team from USA and Italy Includes clinical photographs, diagrams and tables

This book covers several aspects of perinatal tissue-derived stem cells, from theoretical concepts to clinical applications. Topics include functions and different sources, immunomodulatory properties, translational point of view, GMP facility design and manufacturing for clinical translation, therapeutic potentials, and finally ethical considerations. The text provides a brief review of each type of perinatal stem cells and then focuses on their multi- or pluripotent properties, regenerative capacity, and future therapeutic potential in regenerative medicine. Additionally, the book discusses GMP compliance in stem cell facilities and the manufacture of stem cells for clinical translation. The chapters are authored by world-renowned experts in the perinatal stem cell field. Perinatal Tissue-Derived Stem Cells: Alternative Sources of Fetal Stem Cells, part of Springer's Stem Cell Biology and Regenerative Medicine series, is essential reading for basic and clinical scientists, clinicians, and pharmaceutical experts working or conducting research in the fields of stem cell biology, molecular aspects of stem cell research, tissue engineering, regenerative medicine, and cellular therapy.

Sadly, women often feel they have no alternative but to give up breastfeeding, having been prescribed or purchased medication. In many cases, however, this is unnecessary. This book outlines the evidence base for the use of medication during breastfeeding. Breastfeeding and Medication presents a comprehensive A to Z guide to the most frequently prescribed drugs and their safety for breastfeeding mothers. Evaluating the evidence for interventions and using a simple format for quickly identifying medications that are safe or unsafe to use, it also highlights those drugs where there is inconclusive evidence. Additional contextual information makes this the most complete text for those practitioners who support and treat breastfeeding women. It: provides an overview of the anatomy and physiology of the breast together with hormonal influences to better understand how complications, such as mastitis, arise and inform the approach to their treatment; includes a section on conditions that affect women specifically when they are lactating where prescription of medication may be necessary; discusses the importance of breastfeeding and its advantages, as well as its disadvantages; and explores how to support breastfeeding mothers, and presents a counselling model approach. This new edition contains information on more drugs and a chapter on the management of some chronic conditions which may affect breastfeeding mothers. In most cases there are options to support the mother's optimal care whilst allowing her to continue to breastfeed her baby as long as she wishes. This is a topic which raises many questions on social media, which informed the choice of conditions to consider. This is an invaluable reference for all health practitioners and volunteers who work with, support and treat breastfeeding women, including lactation consultants, breastfeeding support workers, health visitors, GPs, practice nurses, pharmacists and midwives.

It is no surprise that women and men experience biological and physiological differences fundamentally and throughout the lifecycle. What is surprising is that faced with such a self-evident truth, there should be so little consideration to date of how these differences affect susceptibility to disease and metabolic response to dietary treatment. Understanding these differences and developing a gender-based approach focusing on the specific needs and conditions of women is crucial to achieve effective nutritional strategies for women's health. Expanding the knowledge-base regarding sex, nutrition, and medicine, Optimizing Women's Health through Nutrition presents the biology, physiology, and metabology unique to women. The book demonstrates in a practical, accessible manner the scientific application of this data addressing lifecycle changes, disease prevention, and treatment. Based on sound research and supported by extensive references, it begins by describing recent research on biological and physiological differences and how these differences translate into varying disease trends between the sexes. Contributions describe the nutritional needs of women during the lifecycle, particularly during adolescence, pregnancy and lactation, premenopause, and menopause and midlife stages. The bulk of the book addresses each of the common major diseases or conditions that specifically affect the health of women. It emphasizes the role of nutrition in disease risk reduction as well as management and treatment of disease. Specific disease selection was dictated by those in which women are more vulnerable or have a higher incidence than men. The concluding section identifies areas for future research and strategic areas of investigation for researchers and health professionals, government regulators, and food industry professionals involved in creating novel foods that enhance women's health.

Originally published in 1982 Obstetrics and Gynaecology in Tudor and Stuart England traces the development of obstetrics and gynaecology over the past two centuries. Between the 16th and 18th century midwifery passed from a female mystery, employing traditional medicines and superstitions, to a scientifically-based clinical skill, with both gains and losses to the patient. The case-mortality was high enough to make the increasing involvement of male surgeons socially acceptable, despite sexual taboos. Thus, as scientific knowledge of anatomy and physiology developed and was applied in the form of new techniques, so the midwives, who had less opportunity and inclination to acquire the new knowledge and skills, lost esteem and by the mid-eighteenth century were increasingly relegated to the service of the poor. The book also examines ideas about sexuality, menstruation, conception, pregnancy and lactation and shows how the views of society about femaleness, marital relations and the management of pregnancy and childbearing were influenced by these notions.

This book provides those studying for the MRCOG Part 2 examination with welcome practice in answering Extended Matching Questions (EMQs). Updated throughout to map onto the MRCOG syllabus from September 2016, the book is designed to test the candidate's theoretical and practical knowledge of obstetrics and gynaecology. An introductory section on exam techniques is followed by a collection of 41 EMQ themes, split into obsterics and gynaecology. The questions are based on common clinical scenarios and cover a variety of topics. Answers are included after each topic, and these include explanatory material and useful references.

Ovarian stimulation is the starting point of reproductive medicine but the procedure can result in adverse reactions particularly the dangerous ovarian hyperstimulation syndrome. Fully revised in line with modern practice of ovarian stimulation, this new edition is divided into six sections that cover mild forms, non-conventional forms, IVF, complications and their management, alternatives, and the practicalities of procedures. All aspects of ovarian stimulation are discussed including the different stimulation protocols from which to choose, the management of poor responders and hyper-responders, as well as stimulation in patients with PCOS. Comprehensively reviewing the modern approach to ovarian stimulation, the alternative procedures are also described, both in IVF and other methods of assisted reproduction. Written by leading experts on reproductive health and fertility, this book will assist infertility specialists, gynecologists, reproductive endocrinologists and radiologists in determining successful treatment for their patients.

Improvements in the detection of fetal and neonatal brain injuries, advances in our understanding of the pathophysiology, cellular and molecular bases of encephalopathy, and new treatment options have all combined to produce significant changes in the management of neonatal brain disorders in the past few years. This new edition of Fetal and Neonatal Brain Injury brings the reader fully up to date with all advances in clinical management and outcome assessment. Updated material includes inflammation focusing in particular on chorioamnionitis and fetal brain injury; genetic brain injury; and expanded sections on cholestasis, diabetes, and thyroid disease. An updated, highly illustrated chapter on structural and functional imaging of the fetal and neonatal brain is also included. An outstanding international team of highly experienced neonatologists and maternal-fetal medicine clinicians have produced a practical, authoritative clinical text that gives clear management advice to all clinicians involved in the treatment of these patients.

Endometriosis causes a variety of symptoms from painful periods and backache to fertility problems. If you have painful periods and wonder if you might have endometriosis, or if you've already been diagnosed, you need the best possible information, help and support. This book aims to help you understand your symptoms, talk to your doctor without embarrassment, and it explains the tests and the treatment options. There's also sympathetic advice to help you cope with pain, deal with your own feelings about having endometriosis, and talk to your partner about how you feel. "Women with endometriosis need simple, clear information to enable them to decide for themselves which kind of treatment may be right for them. This book is written in a clear question and answer format and covers everything from explanations of symptoms to treatments and self-help. A book aimed directly at women, in a language they can understand." - National Endometriosis Society

Offers an expert blend of sound theory and evidence based therapy for residents and practitioners. Provides a clear path through the increasing complexity of ART options and techniques, using clinical experience and common practical sense. Condenses the aspects of knowledge and practice most relevant for learning the practical basics of diagnosis and decision making.

This open access book looks at the dramatic history of ovariotomy, an operation to remove ovarian tumours first practiced in the early nineteenth century. Bold and daring, surgeons who performed it claimed to be initiating a new era of surgery by opening the abdomen. Ovariotomy soon occupied a complex position within medicine and society, as an operation which symbolised surgical progress, while also remaining at the boundaries of ethical acceptability. This book traces the operation's innovation, from its roots in eighteenth-century pathology, through the denouncement of those who performed it as 'belly-rippers', to its rapid uptake in the 1880s, when ovariotomists were accused of over-operating. Throughout the century, the operation was never a hair's breadth from controversy.

Infertility affects about five million individuals of childbearing age in the United States, yet infertility is a subject about which many people are reluctant to talk. This book discusses extensively many options available to individuals struggling with infertility. Infertility can result from a number of causes and affects men and women in equal numbers. Difficulty conceiving can take a heavy toll on couples both physically and psychologically and can lead to depression and marital discord. There are, however, many options available to those struggling with infertility for having a child. These include innovative medical procedures and powerful drugs as well as a variety of alternative treatment approaches, surrogacy, and adoption. A part of Greenwood's Health and Medical Issues Today series, this book provides an overview of these options and examines the many health, financial, and ethical decisions of each that must be considered when choosing one. Part I explores what causes infertility and the history and evolution of its treatment and then examines the options available today, detailing how they work, their success rates, and their risks. Additionally, it addresses controversial topics such as the legislation of assisted reproductive technologies and the regulation of fertility clinics. Part II delves into the many scientific, economic, and ethical debates that surround infertility treatment, presenting a clear and objective analysis of the issues. Part III provides a variety of useful supplementary materials, including case studies, a timeline of critical events, a glossary, and a directory of resources.

Selected as a Doody's Core Title for 2022! Essential for ob/gyn physicians, primary care physicians, and any health care provider working with pregnant or postpartum women, Drugs in Pregnancy and Lactation: A Reference Guide to Fetal and Neonatal Risk, 12th Edition, puts must-know information at your fingertips in seconds. An easy A-to-Z format lists more than 1,400 of the most commonly prescribed drugs taken during pregnancy and lactation, with detailed monographs designed to provide the most essential information on possible effects on the mother, embryo, fetus, and nursing infant. Each templated monograph includes: Generic US name (trade names in index) Risk factors Pharmacologic class Pregnancy and breastfeeding recommendations Pregnancy, fetal risk, and breastfeeding summaries Updated references NEW in the 12th Edition: 100 new drugs, with thorough updates of all existing drugs Subheadings with each review for faster reference List of cross-referenced combination drugs List of drugs contraindicated in breastfeeding women List of drugs contraindicated in pregnancy List of drugs that affect human development Quarterly updates, available online, to keep you at the forefront of the field Greatly improved eBook searchability Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.

This book analyses the reasons for relying on behavioural contraception methods among urban 'elites' in India and examines their efficacy in controlling fertility. It also traces variations in contraception choice over the reproductive cycle of women. Although researchers and policy makers generally equate reliance on behavioural contraceptive methods with low levels of education and awareness and lack of desire to control fertility, this perception has been questioned in recent years. The authors' analysis of the first three rounds of the National Family Health Survey (NFHS) data in India reveals that behavioural contraceptive methods are popular in eastern India. Moreover, it is urban educated women who rely on behavioural methods, and are apparently able to regulate fertility quite effectively with such methods. NFHS data, however, has some limitations and this motivates the authors to explore birth control methods through primary surveys of currently married graduate women in Kolkata. The use of behavioural contraception methods is a little researched area globally and this is the first book focusing on the topic in India.

This book addresses new avenues in child abuse prevention research that will expand our capacity to protect children. These new avenues result from the emergence of new research methods made possible through technologic advances, an understanding of the benefits of cross-disciplinary research and learning and the entrance of many young scholars in the field. The book explores what these avenues produce in terms of clarifying the complex problems that continue to limit our progress in addressing child maltreatment and promoting optimal child development. Specifically, the book showcases individual contributions from emerging scholars and show how these scholars use the frameworks and advanced methods to shape their work, apply their findings and define their learning communities. The book highlights the benefits of creating explicit and extended opportunities for researchers to network across disciplines and areas of interest. The primary authors are young scholars from universities across the U.S. who have worked together as Fellows of the Doris Duke Fellowships for the Promotion of Child Well-Being – seeking innovations to prevent child abuse. Through this program, the Fellows have engaged in a robust self-generating learning network designed to create the type of ongoing professional linkages and decision-making style that fosters an interdisciplinary and team planning approach to research design and policy formation.

Written and edited by leading, internationally recognized clinicians and scientists in reproductive medicine and related fields, this unique text is a practical and comprehensive review of the clinical and scientific significance of unexplained male and female infertility and its management. The book is divided into thematic sections to ensure the most useful presentation of topics, opening with definitions and epidemiology of unexplained infertility, including discussion of the WHO's cutoff values for human semen characteristics and its ramifications. Sections covering male and female reproductive pathophysiology follow respectively, covering biological, genetic and environmental causative factors, with a subsequent section on evaluative techniques for male and female patients. Expectant, medical and surgical treatment strategies comprise the fifth section of the book, where active interventions and outcomes of each treatment modality are carefully considered. The final section discusses assisted reproductive techniques to manage unexplained infertility, such as intrauterine insemination and in vitro fertilization, as well as future perspectives. Thoughtful and enlightening, Unexplained Infertility: Pathophysiology, Evaluation and Treatment will be an invaluable resource for all clinicians and scientists working in the fields of reproductive medicine and infertility.

This volume reviews the evolution of information regarding the epidemiology of DCIS and its modes of detection, as well as treatment options as a function of both clinical trial data and ongoing investigational therapeutic prospects. Several of the challenging and clinically-relevant scenarios of DCIS that appear in daily practice is discussed, including the difficulties of distinguishing "true" DCIS from borderline patterns of other breast diseases and the therapeutic implications of differentiating these various diagnoses. Particular attention is paid to pathologic evaluation of DCIS, including histologic patterns and the importance of margin evaluation/margin control. The text also explores the data regarding DCIS in medical research in hereditary susceptibility for breast cancer and race/ethnicity-associated disparities in breast cancer. Written by experts in the field, Ductal Carcinoma In Situ and Microinvasive/Borderline Breast Cancer is a comprehensive, state-of-the art review of the field, and serves as a valuable resource for clinicians, surgeons and researchers with an interest in breast cancer.

This book systematically reviews and discusses recent studies and articles on the immunology of female genital tract tissue. The scope is broad, encompassing innate immune responses, adaptive (humoral and cell-mediated) immunity, the immunology of menstruation, the immunology of viral and bacterial infections, the immunology of normal and abnormal pregnancy, and immunological infertility. Throughout, tables and illustrations are judiciously used to facilitate understanding. Immunology of the Female Genital Tract will serve as an invaluable source of up-to-date information for all with an interest in this subject.

The Lamaze method is virtually synonymous with natural childbirth in America. In the 1970s, taking Lamaze classes was a common rite of passage to parenthood. The conscious relaxation and patterned breathing techniques touted as a natural and empowering path to the alleviation of pain in childbirth resonated with the feminist and countercultural values of the era. In Lamaze, historian Paula A. Michaels tells the surprising story of the Lamaze method from its origins in the Soviet Union in the 1940s, to its popularization in France in the 1950s, and then to its heyday in the 1960s and 1970s in the US. Michaels shows how, for different reasons, in disparate national contexts, this technique for managing the pain of childbirth without resort to drugs found a following. The Soviet government embraced this method as a panacea to childbirth pain in the face of the material shortages that followed World War II. Heated and sometimes ideologically inflected debates surrounded the Lamaze method as it moved from East to West amid the Cold War. Physicians in France sympathetic to the communist cause helped to export it across the Iron Curtain, but politics alone fails to explain why French women embraced this approach. Arriving on American shores around 1960, the Lamaze method took on new meanings. Initially it offered a path to a safer and more satisfying birth experience, but overtly political considerations came to the fore once again as feminists appropriated it as a way to resist the patriarchal authority of male obstetricians. Drawing on a wealth of archival evidence, Michaels pieces together this complex and fascinating story at the crossroads of the history of politics, medicine, and women. The story of Lamaze illuminates the many contentious issues that swirl around birthing practices in America and Europe. Brimming with insight, Michaels' engaging history offers an instructive intervention in the debate about how to achieve humane, empowering, and safe maternity care for all women.

Breast cancer is the most common cancer in females that accounts for highest cancer specific deaths worldwide. In the last few decades research has proven that breast cancer can be treated if diagnosed at early stages and proper therapeutic strategy is adopted. Omics-based recent approaches have unveiled the molecular mechanism behind the breast tumorigenesis and aid in identification of next-generation molecular markers for early diagnosis, prognosis and even the effective targeted therapy. Significant development has taken place in the field of omics in breast cancer in the last decade. The most promising omics approaches and their outcomes in breast cancer have been presented in this book for the first time. The book covers omics technologies and budding fields such as breast cancer miRNA, lipidomics, epigenomics, proteomics, nutrigenomics, stem cell, pharmacogenomics and personalized medicine and many more along with conventional topics such as breast cancer management etc. It is a research-based reference book useful for clinician-scientists, researchers, geneticists and health care industries involved in various aspects of breast cancer. The book will also be useful for students of biomedicine, pathology and pharmacy.

Endometriosis is one of the most common gynecological diseases, causing pelvic pain, infertility, and cancer. The condition reduces the quality of life for the estimated 10% of menstruating women who are affected by it. This book provides a clear insight into the pathogenesis and pathophysiology of endometriosis—essential information for clinicians intending to successfully treat the condition. The first part covers a range of topics including stem cells, NK cells, macrophages, inflammation, cytokines, epigenetics, prostaglandin, sex steroids, aromatase, apoptosis, nerve fibers, and malignant transformation to aid in understanding the pathogenesis and pathophysiology of the disease. The second part provides useful tools for therapy, specifically, notable recent techniques in prevention, imaging, biomarkers, medical treatments, surgical treatments, prevention of recurrence, and infertility treatments. Each chapter was written by an expert in the field, with nearly 40 researchers and clinicians contributing to the work. This book will be highly useful to clinicians as well as to research scientists who are interested in this enigmatic disease.