APPRAISAL AND REVALIDATION SERIES The new Appraisal and Revalidation Series helps doctors demonstrate their competence to the standard expected by the General Medical Council and to the standard expected if they are recognised as having 'special clinical interests'. It helps doctors gather evidence of their performance for appraisal and revalidation portfolios. This fifth book in the series examines the practical ways to identify learning and service needs within the areas of substance abuse palliative care musculoskeletal conditions and prescribing practice. It also provides guidance on how to collect data to demonstrate learning competence performance and service delivery standards. All general practitioners and those with special clinical interests and primary care organisation leads will find this book essential reading. For more information on other titles in this series please click here

The fourth volume in the Atlas of Human Central Nervous System Development series, The Human Brain During the Late First Trimester provides new information about features of the perinatal brain. It deals with brain development during the late first trimester (GW11-GW7.5). The major theme of this volume is the identification of stretches and patches (mosaics) of the NEP matrix along the hypertrophied telencephalic, diencephalic, mesencephalic, and rhombencephalic superventricles. Many putative migratory paths of young nerons on their way to their settling sites are also identified. In the younger specimens, the brain sections are presented as they are embedded in the skull and developing facial structures. The older specimens show the onset of development of some of the large fiber tracts. Like the rest of the series, it contains photographs of the entire brain arranged in companion plates that include two parts: a large, high resolution black and white photograph and a "ghost image" of the photograph with unabbreviated labels. It is a user-friendly survey of the complex structural processes that occur during human CNS development. This volume can be purchased as part of the complete five volume set.

The major objective of our studies in the last decade was a systematic analysis of maternal diseases during pregnancy to reveal their possible adverse effects on birth outcomes. The two most important factors of infant mortality were parti- larly analyzed: structural birth defects, known as congenital abnormalities (CAs) and preterm birth (PB). In general the objectives of scienti c studies might be either to test a new hypothesis or to con rm or confront previously published results. However, less frequently the authors/scientists have personal motivations determined by their professional activities. The authors of this book are practicing physicians and genetic epidemiologist who are mainly interested in the following three practical questions: 1. The possible adverse effects of pharmaceutical products. The possible t- atogenic potential of about 170 drugs has been evaluated very thoroughly using the data set of the Hungarian Case-Control Surveillance of Congenital Abnormalities (HCCSCA) in the last 50 years. These drugs were used to treat maternal diseases and the ndings of our population-based case-control studies will be cited in this book and are shown in the Appendix at the end of the book. However, our long experiences showed two problems in the drug teratology. In general the evaluation of clinical doses of these drugs is a particularly dif- cult challenge due to the modi cation effects of confounders. This problem motivated one of the authors to establish a new model of disaster epidemiology.

Expanded by 30% to explore the latest surgical approaches, techniques, equipment, and perspectives, this Second Edition leads surgeons through new applications in minimally invasive surgery, gynecology, urology, endoscopically-assisted plastic surgery, pediatric surgery, and video-assisted thoracoscopic procedures.

1. Clinical cases set out as questions that are mapped directly to the curriculum and following the order of the RCoA curriculum 2. A focus on clinical anaesthesia with common cases, that can be used in the clinical environment either for teaching or as a refresher 3. Short, quick-fire cases that enable learning and retention of information with a summary of key points to remember for each question

This beautifully illustrated book provides a practical step-by-step guide to all the laparoscopic and hysteroscopic procedures performed by gynecologists. Each procedure is described in detail and fully illustrated with color photographs. The potential complications are described, and the circumstances in which a procedure is contraindicated are examined. The Third Edition of the "Manual of Laparoscopic and Hysteroscopic Techniques" has been expanded and extensively updated with new chapters including: transvaginal hydrolaparoscopy, laparoscopy radical trachelectomy, laparoscopic abdominal cerclage, and hysteroscopy sterilization. "Manual of Laparoscopic and Hysteroscopic Techniques" is an invaluable resource for busy practicing gynecologists who want to learn step-by-step techniques of a surgical procedure.

Gestational Diabetes Mellitus is becoming an increasingly prevalent disease as obesity and other chronic diseases are on the rise. It requires careful and informed clinical management as the care received during pregnancy affects not only perinatal health but the risk of developing type 2 diabetes even decades into the future, in both the mother and the child.From epidemiology and pathophysiology to diagnosis and management, covering recent breakthroughs in research and up-to-date developments in clinical practice, Gestational Diabetes During and After Pregnancy offers the reader a comprehensive and current look at Gestational Diabetes. Anyone involved in the research, public health or clinical aspects of Gestational Diabetes will find this volume a valuable aid in consolidating all recent developments regarding this disease.

Get Through MRCOG Part 2: MCQs covers the breadth and depth of the MRCOG Part 2 examination syllabus and is an essential revision tool for candidates preparing for this examination. The comprehensive and wide collection of practice questions is designed to help the candidate test and assess their knowledge of the subject, aiding them in thorough preparation for the exam. The text contains 750 multiple choice stems, each with around four associated questions, providing the reader with a total of 3000 individual questions with which to test themselves. The material is divided up by subject area, allowing candidates to test their knowledge on a particular topic. The 13 'modules' are followed by two mock papers, each containing a selection of questions on different subject areas, which the reader can attempt under timed conditions. Answers are provided, with useful explanatory information for all questions to help the reader understand why their answer is right or wrong. The author, Paul Ayuk, was clinical lecturer in obstetrics and gynaecology at Oxford University for 6 years and has run an on-line MRCOG course for over 5 years, assisting over 8000 candidates worldwide.

This book contains a series of clinical cases that address and illustrate difficult problems in obstetric ultrasound. The approach is strongly didactic and will aid trainees in maternal-fetal medicine and obstetrics to appreciate potential pitfalls and recognize rare presentations. Each case sets out one page of text, then one of treatment algorithms, and then presents sample ultrasound scans. Learning objectives are given for each case, together with a short list of references and background reading.

The impact of hormones on deep venous thrombosis is one of the most charged and debated subjects in contraceptive medicine. Female hormonal balance is primarily affected by the use of either oral contraceptives or HRT. For a long time it has been recognized that oral contraceptives can raise the incidence of DVT; however, there has been an enormous controversy as to whether all progestins do this equally or whether some have a greater impact than others where oral contraception is concerned. Written by a world leader on the subject, this book offers the latest clinical information about the effects of pregnancy, the contraceptive pill, and hormone replacement therapy on thrombotic problems in women.

The discovery of ER by Dr. Elwood Jensen exactly 60 years ago has not only led to the birth of a whole new vital nuclear receptor research field but also made a rapid, direct and lasting impact on the treatment and prevention of breast cancer. Since that landmark discovery, tremendous progress has been made in our understanding of the molecular functions of ER and development of targeted therapies against ER pathways for breast cancer treatment. However, there is currently no book available addressing these discoveries and recent advancement in a historical and systematic fashion. This book is intended to provide comprehensive, most up-to-date information on the history and recent advancement of ER and breast cancer by world renowned leaders in the field. These chapters include the history of the discovery of ER; physiological and pathological roles of ER; recent discovery of ER cistrome, transcriptome and its regulation of noncoding RNAs such as microRNAs and enhancer RNAs in breast cancer; development and clinical practices of the first targeted therapy Tamoxifen and other antiestrogens for breast cancer treatment; structural basis of ER and antiestrogen actions; molecular insights into endocrine resistance; the role of ER mutants, ER-beta and environmental estrogens in breast cancer; and emerging state-of-the-art therapeutic approaches currently in development to overcome treatment resistance and future perspectives. The book will provide undergraduate and graduate students, basic scientists and clinical cancer researchers, residents, fellows, as well as clinicians, oncology educators and the general public a thorough and authoritative review of these exciting topics.

Regarded as the leading textbook in obstetrics and gynaecology for over 50 years, Fundamentals of Obstetrics and Gynaecology is an ideal introduction to the basic principles of this specialty for medical students, trainees, midwives and nurses. Intervention rates continue to climb; women in the developed world embark on pregnancy later in life and with more complex medical disorders. The need to know and apply the best available standards of care is ever more critical. The book comprehensively and clearly presents all the major components of women's reproductive health, from the basics of history and examination through to pelvic anatomy, development of the fetus, and maternal psychosocial issues. Fully updated in its eleventh edition by experts in their field, this much-loved book remains true to the vision of its first author, renowned Australian obstetrician Derek Llewellyn-Jones OBE - to apply the best available standards of care for women throughout their reproductive journey. In his words: 'It is our hope to continue to meet the needs of today's medical students and students of nursing and midwifery; and to encourage self-learning skills while providing essential information in a readable manner'. New chapters on weight and reproductive health and polycystic ovarian syndrome Hot topics covered include changes to cervical screening, disorders of sexual development, and COVID in pregnancy Concise and readable Suitable for students of medicine, midwifery and women's health Clear, integrated approach - easy to follow Highly illustrated in full colour throughout

Covers gestational and chronic hypertension in addition to severe preeclampsia, eclampsia, and HELLP syndrome and discusses the interaction with the renal, hematological, neurological, and hepatic systems of pregnant women.

Find real-world, clinically useful information on all aspects of electronic fetal monitoring! Written by clinicians for clinicians, Mosby's Pocket Guide to Fetal Monitoring: A Multidisciplinary Approach, 9th Edition provides an evidence-based, collaborative approach to fetal heart monitoring during labor and in the antepartum period. It covers the physiologic basis for FHR monitoring, methods and instrumentation, standardized terminology, pattern recognition and interpretation, and management of care. Authored by a nurse-midwife, a perinatologist, and a nurse, this compact guide prepares you for success on the EFM certification exam and for success in today's clinical practice. Pocket-sized format makes this guide ideal to carry and use in the clinical setting, and a colorful design makes information easier to find. Coverage of fetal heart rate assessment, evaluation, interpretation, and management is supported by evidence-based practice and literature, helping you prioritize care and make clinical decisions. Patient safety and risk management strategies include case studies and legal commentary, plus guidelines for providing safe and competent care. Information on the relationship between fetal heart rate patterns and neonatal outcomes provides a guide to the correct use of fetal monitoring. Illustrations, tables, and fetal monitor tracings highlight critical information. Coverage of innovative practices supports patient safety and improved outcomes through the use of a common language for fetal heart rate patterns, a standardized approach to interpretation, a discussion of emergency preparedness, and a discussion of human factor issues such as improved communication, situational awareness, no-fault/just culture, and teamwork. Practical appendices offer a guide to FHR tracings and interpretation as well as self-assessment questions for credentialing and certification exam preparation. Expert author team provides clinical insight along with international presence. NEW information on Category II tracing management is included. NEW! Expanded section on common misconceptions and myths includes evidence supporting factual EFM characteristics. NEW! Detailed information on documentation and legal issues is added. NEW EFM tracings with interpretation are added.

Now in its second edition, this bestselling title has been extensively revised and expanded to include new topics on: obesity and breast cancer induction of anti-hormone and anti-growth factor resistance in breast cancer clinical implications of testosterone and breast cancer insulin-like growth factors discussions on the biological, genetic, and molecular pathways linked to the development and progression of breast cancer analyses on the latest therapeutic strategies, prognostic and predictive factors, and prevention strategies Examining new developments, Breast Cancer: Prognosis, Treatment, and Prevention, Second Edition also covers: the mechanism involved in carcinogenesis the relationship among a fetus, pregnancy, and breast cancer recent developments in endocrine treatment the relationship among hormone replacement therapy, cytotoxic therapy, and other non-hormonal approaches for the treatment of metastases management of locally advanced breast cancer, and the importance of BRCA-1 and BRCA-2 in hereditary breast cancer With new topics and updated chapters, this new edition keeps both oncologists and radiologists abreast of the current trends and advancements in the prognosis, treatment, and prevention of breast cancer.

The potential impact of work being conducted in genomics, proteomics, and metabolomics upon clinical practice for gynecologists is immense but not yet completely appreciated. This groundbreaking text from international experts examines the newest topics on the perinatal agenda and gives clinicians a real look into the future via the newest methodologies.

Understanding immunology is increasingly important in obstetrics and gynecology. Written primarily to meet the needs of practicing obstetricians and gynecologists, this book explores the role of immunological processes in reproduction. It presents immunologic concepts and illustrates important points with examples familiar to the clinician. The book is organized into four sections that explore the fundamentals of the immune system, the immunological paradox of pregnancy, clinical applications of immunology in obstetric and gynecologic practice, and immunopathology in obstetric and gynecologic practice. Written mainly for practicing obstetricians and gynecologists, the research results cited in the book are based on human experimentation. Fully illustrated with clear schematic drawings that highlight important concepts and processes, The Immunology of Human Reproduction gives readers an essential overview of immunology as it relates to human reproduction.

Based on the protocols in use at the highly acclaimed King's College Hospital in London, Clinical Protocols in Labour presents a consensus of the best and most appropriate techniques for standard delivery and uncommon clinical scenarios. Each chapter is written as a stand-alone unit making the information easy to find. Coverage ranges from a general approach to care, normal labour, and care of the baby to specific issues such as eclampsia and pre-eclampsia, uterine rupture, and postpartum bleeding. In addition, the book includes protocols for emergency closure of the labour ward, communication among members of the labour team, and more. A compact, authoritative volume, Clinical Protocols in Labour provides practical templates for the perinatal management of women and their babies during labour and delivery.

This is a new book on the integrated management of vulvovaginal disease. The authors come from a variety of backgrounds - gynaecology, dermatology, pathology and psychology - and describe a multidisciplinary approach to these conditions. The book has the most complete classification of vulvovaginal disease published, based on the etiology of 275 conditions; coverage includes benign, malignant, and functional (including psychosexual) diseases. Each disease has a descriptive summary, pathological features, and treatment guidelines. The book is illustrated in full color throughout.

The Diploma of the Royal College of Obstetricians and Gynaceologists (DRCOG) examination consists of 60 multiple choice questions (MCQs) and 22 six minute structured clinical examination stations (OSCEs), of which two are rest stations. This one day examination is designed for General Practice trainees, ideally with six months' experience in obstetrics and gynaecology at the senior house officer grade.This book presents three complete DRCOG MCQ and OSCE circuits and encompasses all the possible MCQ and OSCE topics that can and have been asked in the DRCOG examination. They are presented in an identical way to the exam itself.The author, Mrs Una Coales MD, FRCSEd, DRCOG, trained in medicine in the USA and moved to practise in the UK. She has taken and passed the DRCOG exam herself and has also published popular exam texts for PLAB Parts 1 and 2.

There are many possible causes of pelvic pain in a non-pregnant female patient, and it has been estimated to be responsible for nearly 40% of all visits by female patients to a family doctor and 10% of all referrals to specialist gynecologists. However, the topic of how to investigate and diagnose has been surprisingly neglected in print. This important and much-needed text from internationally respected experts shows how important ultrasound can be as a tool for physicians caring for women's health.

This extensively illustrated book provides an accessible and up-to-date introduction to obstetric anaesthesia and analgesia. With only three principal authors, there is a consistency of style within a comprehensive textbook that presents the basic science, pharmacology and clinical practice relevant to obstetric anaesthesia. Chapters cover topics such as analgesia during labour, anaesthesia and postoperative analgesia for caesarean delivery, major obstetric and anaesthetic complications, evaluation of the foetus and resuscitation of the neonate, and common clinical scenarios such as management of pre-eclampsia, obesity, multiple gestation and co-existing disease.

This title is designed to help the candidate in preparation for the short essay paper components of the written MRCOG Part II examination. By providing a section of model answers with bullet points indicating specific points where marks are allocated, this text provides the candidate with a firm grounding in examination principles and technique for the short essay question papers. A section of practice papers is provided, 10 in obstetrics and 10 in gynaecology with marking schemes by which the reader can test their knowledge under examination conditions. Also valuable as a revision aid, this book highlights the core information that is central to all the MRCOG Part II examination components.

This collection brings together the leading research in maternity care from the United States, Canada and Europe to discuss systems of care for pregnancy and childbirth. The essays focus on the practical side of "good" social science and "feminist-friendly" research. The text not only looks at maternity, but also the act of childbirth, with the goal of providing not just comparative perspectives of care, but also to integrate the differences in care within each essay for a truly international understanding of maternity care.

Ancient Egyptian medicine employed advanced surgical practices, while the prevention and treatment of diseases relied mostly on natural remedies and magical incantations. In the first of three volumes, The Medicine of the Ancient Egyptians explores these two different aspects, using textual sources and physical evidence to cast light on the state of ancient medical knowledge and practice and the hardships of everyday life experienced by the inhabitants of the land on the Nile. The first part of the book focuses on ancient Egyptian surgery, drawing mainly on cases described in the Edwin Smith papyrus, which details a number of injuries listed by type and severity. These demonstrate the rational approach employed by ancient physicians in the treatment of injured patients. Additional surgical cases are drawn from the Ebers papyrus. The chapters that follow cover gynecology, obstetrics, and pediatric cases, with translations from the Kahun gynecological papyrus and other medical texts, illustrating a wide range of ailments that women and young children suffered in antiquity, and how they were treated. Illustrated with more than sixty photographs and line drawings, The Medicine of the Ancient Egyptians is highly recommended reading for scholars of ancient Egyptian medicine and magic, as well as for paleopathologists, medical historians, and physical anthropologists.