This issue provides a timely update for for the ob/gyn on genetics in reproductive medicine. Dr. Dugoff has created an issue with the goals of providing the most currently clinical information on genetic screening and prenatal genetics. Top authors have written reviews on the following topics: Genetic counseling overview for the ob/gyn; Cell-free DNA screening for aneuploidy; Cell-free DNA screening for single gene disorders; The use of microarray in prenatal diagnosis; Whole exome sequencing: Applications in prenatal diagnosis; Screening for aneuploidy in multiple gestations: The challenges and available options; Expanded carrier screening; Ethnicity-based carrier screening overview; Prenatal genetic diagnosis and prenatal genetic screening; Ethical issues in prenatal genetics; Ultrasound findings and associated genetic syndromes; Hereditary cancers in gynecology: and What physicians should know about genetic testing, screening and risk reduction. Readers will come away with the knowledge they need to diagnose, treat, and manage patients based on the most current evidence and data.

1. Clinical cases set out as questions that are mapped directly to the curriculum and following the order of the RCoA curriculum 2. A focus on clinical anaesthesia with common cases, that can be used in the clinical environment either for teaching or as a refresher 3. Short, quick-fire cases that enable learning and retention of information with a summary of key points to remember for each question

This casebook profiles exceptional traumatic injury prevention programs from all over the globe. Its detailed description and analysis employ a multi-stage process of identifying, evaluating, and casing effective prevention practices. The case studies reflect how legislative and regulatory information impact prevention efforts and provide insight into how national centers for injury prevention and control inform prevention practices on countrywide levels. The authors work with outcome-based research criteria to select and develop their comprehensive and contextually aware profiles of the programs. All included case studies follow the BRIO approach (Background, Resources, Implementation, and Outcome) - a model designed to provide a consistent way of describing programs that have been evaluated and found to be exceptional practices. The scope of the Casebook ranges across: The challenge of traumatic injury prevention Sports and recreation-related traumatic injury prevention Fall-related traumatic injury prevention Road traffic-related traumatic injury prevention Traumatic injury prevention within complex systems In its recognition of traumatic injury prevention across the lifespan as a critical and complex public health challenge, the Casebook of Traumatic Injury Prevention promises to be an influential and authoritative resource for professionals and students in public health, safety, injury prevention, medicine, psychology, sociology, nursing, and engineering. Government agencies and institutions such as the Centers for Disease Control and Prevention (CDC), public health departments, and safety associations also would find the Casebook relevant to their work.

This practical, two-volume handbook is the first to illustrate the use of transvaginal color doppler in obstetrics and gynecology. It provides a critical look at state-of-the-art ultrasound techniques and equipment and serves as a comprehensive reference with numerous black/white and color ultrasonograms, tables and graphs. The volumes include extensive literature citations which assist the investigator in finding more in-depth references. This work focuses on the recent remarkable expansion in both diagnostic techniques and clinical applications. It reports findings based on an unusually large patient population over a long period of time. It presents the accuracy and limitations of various aspects of ultrasound. This important publication is especially helpful for clinicians and researchers.

First Edition Named a 2013 Doody's Core Title! First Edition Second Place AJN Book-of-the-Year Award Winner in Maternal and Child Health! With more women than ever seeking obstetric triage and emergency services in obstetric triage units, obstetric providers need to be aware of triage assessment and evaluation protocols. This prize-winning pocket guide, containing management guidelines for obstetric triage/emergency settings, delivers critical information on obstetrics, midwifery, emergency, and family care for both students and seasoned clinicians. As with the first edition, all of the newly revised chapters take a strong collaborative and interprofessional approach to clinical conditions in the obstetric triage setting. With specific clinical protocols for more than 30 clinical situations, this fully updated second edition includes two completely new chapters on sepsis in pregnancy and triage acuity tools, along with updated guidelines for hypertension, sepsis, and postpartum complications. Each protocol comprises presenting symptomatology, patient history and data collection, physical exam findings, laboratory and imaging studies, differential diagnosis, and clinical management protocol/follow up. Plentiful figures and images, reference tables and standardized forms for reference and usage, algorithms, and clinical pathways illustrate chapter content. Esteemed contributors include midwives, nurse practitioners, obstetricians, gynecologists, and maternal fetal medicine faculty who evaluate nearly 30,000 OB visits per year. New to the Second Edition: New chapters on sepsis in pregnancy and triage acuity tools Key updates on ectopic pregnancy, nausea and hyperemesis in pregnancy, severe preeclampsia, sexually transmitted and other infections, substance abuse, and psychiatric disorders in pregnancy Expanded information on periviable obstetric management Information on Zika and Ebola Clinical callouts in each chapter highlighting key points Enhanced narrative protocols Key Features: Provides interprofessional triage protocol guidance for ED and OB triage settings Delivers protocols and guidelines for over 30 emergent care situations Includes plentiful diagnostic and imaging guidelines with accompanying figures Formatted consistently for quick access Offers algorithms, protocols, diagnostic imaging, and best evidence for each condition

Numerous issues confront women's healthcare today, among them the medicalization of women's bodies, cosmetic genital surgery, violence against women, HIV, perinatal mental health disorders. This volume uniquely explores such difficult topics and others at the intersection of clinical practice, policy, and bioethics in women's health care through a feminist ethics lens. With in-depth discussions of issues in women's reproductive health, it also broadens scholarship by responding to a wider array of ethical challenges that many women experience in accessing health care. Contributions touch on many themes previously tackled by feminist ethics, but in new, contemporary ways. Some chapters expand into new fields in the bioethics literature, such as the ethical issues related to the care of Indigenous women, uninsured refugees and immigrants, women engaged in sex work, and those with HIV at different life stages and perinatal mental health disorders. Authors seek to connect theory and practice with users of the health system by including women's voices in their research. Bringing to bear their experience in active clinical practice in medicine, nursing, and ethics, the authors contemplate new conceptual approaches to important issues in women's healthcare, and make ethical practice recommendations for those grappling with these issues. Topical and up-to-date, this book provides a valuable resource for physicians, nurses, clinical ethicists, and researchers working in some of the most critical areas of women's health and applied ethics today.

Bringing together the most up-to-date information on congenital Mullerian anomalies, this comprehensive text explores advances in understanding the embryological causes of these malformations, the systems used to classify the many types of malformation that may be seen, and the field's current diagnosis, evaluation and management techniques. Surgical strategies, including minimally invasive techniques, are described in detail, with chapters divided into two sections: vertical anomalies, such as imperforate hymen, transverse genital septum, and cervical and Mullerian agenesis; and lateral anomalies, such as septate, unicornate and bicornate uterus, uterus didelphys and obstructed hemivagina. Aimed at helping to maintain the future reproductive needs of the patient utilizing assisted reproductive technologies, this book is an excellent reference for OB/GYN surgeons and reproductive medicine specialists treating both adolescent or adult patients with these congenital malformations.

This practical, two volume handbook provides a critical look at state-of -the-art ultrasound techniques and equipment. It is a comprehensive reference with numerous black/white and color ultrasonograms, tables and graphs. The volumes include extensive literature citations which assist the investigator in finding more in-depth references. This work focuses on the recent remarkable expansion in both diagnostic techniques and clinical applications. It reports findings based on an unusually large patient population over al long time period. It presents the accuracy and limitations of various aspects of ultrasound.

Key Features: 1. Provides inclusive and consolidated contents on disorders of female genital skin and mucosa. 2. Features high-quality illustrations and impressive treatment algorithms, making it a ready reckoner for dermatologists, gynaecologists, and general physicians. 3. Facilitates diagnosis and further management of vulvar disease in the skin of colour, thus optimizing patient care.

There is general consensus regarding threshold levels that describe the gray zone on the limits of viability, and gestational age alone should not be used solely in making a decision. This issue will bring light to the latest thoughts and clinical recommendations for delivery during the periviable period. Top thought leaders and clinicians have submitted articles in the following areas: Consequences of Birth at Periviable Gestions on Organ Systems; Medical and Surgical Interventions Before Birth; NICU Care: Nutrition/NEC; Pulmonary Care and Circulatory Support; NICU Stay and Microbiome; and Ethical Considerations and Counseling, to name a few. Readers will come away with the most current content written on this topic and details that can be incorporated into clinical care.

In the last decades, major advances have been made in assisted reproductive technologies (ART) and the public demand for these procedures has increased globally. All ART clinics, from those just starting out to the well established, must employ the latest equipment and implement the best practices, while ensuring that their resources are effectively engaged to optimize patient outcomes. This is a tenet of the fiduciary role of physicians and it is increasingly recognized as a quantifiable goal regulated by formal certifications and accreditations. Quality management protocols such as those proposed by the International Organization for Standardization (ISO) are being rapidly adopted as standards of measure. Quality Management in ART Clinics: A Practical Guide provides easily adoptable ways to implement and improve formalized quality management systems. Essential to any clinic to achieve best practices and maintenance of formal regulatory certifications, this book brings together the know-how of experienced opinion leaders operating in key areas worldwide. The book offers an overview of primary regulations in the ART field, with attention to quality management demands, and links specific requirements to practical steps for implementation. Filled with process and procedure examples, flow diagrams and administrative form templates, this book is the first of its kind, gathering the necessary elements for optimizing practice, management, and quality assurance.

Since 2006, when the "morning-after pill" Plan B was first sold over the counter, sales of emergency contraceptives have soared, becoming an $80 million industry in the United States and throughout the Western world. But emergency contraception is nothing new. It has a long and often contentious history as the subject of clashes not only between medical researchers and religious groups, but also between different factions of feminist health advocates. The Morning After tells the story of emergency contraception in America from the 1960s to the present day and, more importantly, it tells the story of the women who have used it. Side-stepping simplistic readings of these women as either radical feminist trailblazers or guinea pigs for the pharmaceutical industry, medical historian Heather Munro Prescott offers a portrait of how ordinary women participated in the development and popularization of emergency contraception, bringing a groundbreaking technology into the mainstream with the potential to alter radically reproductive health practices.

Based on the protocols in use at the highly acclaimed King's College Hospital in London, Clinical Protocols in Labour presents a consensus of the best and most appropriate techniques for standard delivery and uncommon clinical scenarios. Each chapter is written as a stand-alone unit making the information easy to find. Coverage ranges from a general approach to care, normal labour, and care of the baby to specific issues such as eclampsia and pre-eclampsia, uterine rupture, and postpartum bleeding. In addition, the book includes protocols for emergency closure of the labour ward, communication among members of the labour team, and more. A compact, authoritative volume, Clinical Protocols in Labour provides practical templates for the perinatal management of women and their babies during labour and delivery.

Written by many of the world's leading lactation experts, the Textbook of Human Lactation incorporates evidence-based scientific knowledge to address key topics of importance in breastfeeding such as Anatomy and Biochemistry, Immunobiology, Breastfeeding Management in Infant and Mother, Maternal and Infant Nutrition, and Medications and Breastfeeding. Specific and detailed information is provided on the following: Complete description of the anatomy and physiology of the lactating breast Detailed explanation of the immunobiology of human milk Description of difficult syndromes and conditions in the infant and breastfeeding mother, and how to overcome these challenges Thorough discussion of the of the emotional and physiological component of breastfeeding, especially as it relates to mother/infant co-sleeping Detailed description of the nutritional competition and components of human milk Explanation of the science of drug transport into human milk, and the use of medications in breastfeeding mothers Discusses breastfeeding in the context of important topics such as infertility, polycystic ovary syndrome (PCOS), vitamin D, birth spacing, and family planning.

Trying to get pregnant is enough to make any woman impatient. "The Impatient Woman's Guide to Getting Pregnant "is a complete guide to the medical, psychological, social, and sexual aspects of getting pregnant, told in a funny, compassionate way, like talking to a good friend who's been through it all. And in fact, Dr. Jean Twenge "has "been through it all--the mother of three young children, she started researching fertility when trying to conceive for the first time. A renowned sociologist and professor at San Diego State University, Dr. Twenge brought her research background to the huge amount of information--sometimes contradictory, frequently alarmist, and often discouraging-- that she encountered online, from family and friends, and in books, and decided to go into the latest studies to find out the real story.
The good news is: There is a lot "less "to worry about than you've been led to believe. Dr. Twenge gets to the heart of the emotional issues around getting pregnant, including how to prepare mentally and physically when thinking about conceiving; how to talk about it with family, friends, and your partner; and how to handle the great sadness of a miscarriage. Also covered is how to know when you're ovulating, when to have sex, timing your pregnancy, maximizing your chances of getting pregnant, how to tilt the odds toward having a boy or a girl, and the best prenatal diet.
Trying to conceive often involves an enormous amount of emotion, from anxiety and disappointment to hope and joy. With comfort, humor, and straightforward advice, "The Impatient Woman's Guide to Getting Pregnant "is the bedside companion to help you through it.

Drs. Robert Gaiser and Oni Onuoha have assembled an expert team of authors on the topic of "Obstetric Anesthesia". Article topics include: Epidural Analgesia for Labor: Continuous Infusion vs Programmed Intermittent Bolus; Prophylaxis and Management of Obstetric Hemorrhage; The Use of Ultrasound in Obstetric Anesthesia; Huddles and Debriefings: Improving Communication on Labor and Delivery; General Anesthesia during the Third Trimester: Any Link to Neurocognitive Outcomes; Obstetric and Anesthetic Approaches to External Cephalic Version; Update in the Management of Patients with Pre-Eclampsia; Optimal Pain Management After Cesarean Delivery; Should Nitrous Oxide be Used for the Laboring Patient?; Tilts and Full Stomach: Changes in Anesthesia for Cesarean Delivery; and Post-Dural Puncture Headache: An Evidence Based Approach.

One of modern healthcare's most controversial areas, reproductive medicine is an emerging discipline that fosters hugely divergent opinions on topics such as laboratory techniques, clinical management and ethical considerations. Highlighting over 50 contentious topics in reproductive medicine, this book presents expertly argued opinions are presented for and against, often with diametrically opposing views about management. Debates such as these are being increasingly used as learning tools, helping participants develop their critical thinking skills and showing that context is vital when making decisions. Issues discussed include limits on IVF provision, ethical queries about sex selection, embryology, and ovarian stimulation. Authors are authorities in their field, combining years of experience with fresh and innovative ideas to structure their arguments. Readers will gain an insight into topical controversies, critically evaluating the different sides to enhance their own clinical practice.

Preterm birth interrupts the normal developmental progression of most organs, particularly when birth occurs at the lowest level of viability. An immediate task is to successfully transition to a post-natal life without a placental circulation. To do this demands careful management of the cardiorespiratory systems. To best help the fragile preterm infant at this demanding time, care-givers must remember two most pressing goals. These are first to maintain adequacy of gas exchange and delivery, while simultaneously minimizing any secondary injury to the fragile preterm lung. However, after these immediate priorities in the delivery room, the longer term effects of an immature lung development and its associated problems come to the forefront. These problems include the inflammation of perinatal infection, oxygen, and invasive mechanical ventilation. Both the immaturity itself, and secondary lung injury and its inflammation - collectively will often lead to the condition termed bronchopulmonary dysplasia (BPD). Although many of these infants may eventually be discharged to home without a need for oxygen supplementation or pulmonary medications, the long-term impact of interrupted lung development and secondary lung injury remain serious concerns. It is now well recognized that mechanical ventilation is pivotal to developing secondary lung injury and BPD. Consequently, a great deal of time and effort has been put into the development and application of non-invasive ventilator (NIV) approaches to supporting respiratory function in neonates. Since the landmark publication by Gregory and colleagues in 1967, nasal continuous positive airway pressure (nCPAP) has been the most commonly applied approach to NIV. This approach has been supported by the recent generation of randomized controlled trials. However, cumulatively these trials have shown only a small reduction in rates of BPD. Outside of the trial data, despite the wider application of nCPAP, rates of BPD remain relatively unchanged over recent years. This has led to investigations of other NIV approaches including nasal ventilation and high flow nasal cannula therapy. Not only have available modes increased, but so have the interfaces through which these modes may be applied. In the issue of Clinic in Perinatology, readers will find an up-to-date review of non-invasive approaches to supporting preterm respiratory function. This draws on the expertise of leading investigators in the field. This issue reviews the physiologic mechanisms by which the various approaches to NIV may support respiratory function; the evidence base supporting different NIV approaches; and adjunctive aspects of NIV therapy including their use during neonatal transport and the application of other supportive therapies such as inhaled NO.

A strikingly effective, one-of-a-kind learning resource This one-of-a-kind learning resource for Neonatal Nurse Practitioner/CNS students in both academic and clinical settings is distinguished by its use of complex case studies to reinforce best practices in treating vulnerable neonatal patients. Based on applications and outcomes, the case study approach is a particularly effective method of enhancing critical thinking and clinical decision-making and fostering effective role transition in practice-based disciplines. Authored by leading NNP educators nationwide, these multi-faceted, unfolding case studies address and synthesize the most important content covered throughout the NNP curriculum. Topics addressed include maternal/neonatal complexities, risk factors, neonatal disorders and emergencies by body system, health promotion/maintenance, communicating effectively with parents, and guidance on handling unexpected outcomes. Case studies progress from basic to complex, and each includes objectives, clinical pearls, and critical thinking questions. A robust instructor toolkit contains pedagogical strategies for facilitating online discussion, chapter conclusion quizzes, a variety of simulation experiences, and more. Key Features: Uses a complex case-based learning approach for neonatal advanced practice nursing - the first book to do so Authored by leading NNP educators nationwide Provides 40-50 case studies synthesizing key content areas Helps prepare students for effective role transition Includes a robust instructor toolkit and can be used in online courses

This issue of the Surgical Pathology Clinics, edited by Drs. Blaise Clarke and Glenn McCluggage, focuses on Gynecologic Pathology. Topics covered in the issue include, but are not limited to: Gynecologic manifestations of the DICER1 syndrome; Prophylactic gynecologic specimens from hereditary cancer carriers; Lynch syndrome associated endometrial cancer; Peutz-jeghers syndrome associated gynecologic tumors; Gynecologic manifestations of less commonly encountered hereditary syndromes; and Clinical testing for hereditary predisposition.

Evidence-based clinical guidelines are designed to provide systematically developed recommendations to assist clinicians and their patients in making decisions about appropriate treatment for specific conditions. While these may often be widely available, nowhere are they collated into a single, practical text. This book will fill this need for those working in maternal-fetal medicine, comprehensively covering the conditions, diagnostic and therapeutic challenges faced by those working in fetal care. Presented in highly illustrated, algorithm format with fetograms and autopsy correlations included, this book will aid in the diagnosis, investigation, counselling and therapeutic options for the management of fetal abnormalities and disorders.

Written by medical specialists and faculty of the Department of Obstetricians and Gynaecology, National University Health Services, Integrated Approach to Obstetrics and Gynaecology is a textbook for medical undergraduates and residents.This textbook is unique in that it takes an integrated approach in discussing the six phases in the life of a woman, namely, the early years of growing up, the reproductive years, pre-conception, early pregnancy, pregnancy care, and functional ageing in a mature woman.Emphasis has been focused on information that constitutes essential 'core knowledge' in the blueprint of the medical undergraduate curriculum. The format is easy to follow: background introduction to history; examinations and investigations to establish a diagnosis and then treatment and management. However, this may have to be modified as deemed appropriate for a particular topic. Where appropriate, knowledge that is 'good to know' has been incorporated beyond the essential 'core knowledge'.

Written by medical specialists and faculty of the Department of Obstetricians and Gynaecology, National University Health Services, Integrated Approach to Obstetrics and Gynaecology is a textbook for medical undergraduates and residents.This textbook is unique in that it takes an integrated approach in discussing the six phases in the life of a woman, namely, the early years of growing up, the reproductive years, pre-conception, early pregnancy, pregnancy care, and functional ageing in a mature woman.Emphasis has been focused on information that constitutes essential 'core knowledge' in the blueprint of the medical undergraduate curriculum. The format is easy to follow: background introduction to history; examinations and investigations to establish a diagnosis and then treatment and management. However, this may have to be modified as deemed appropriate for a particular topic. Where appropriate, knowledge that is 'good to know' has been incorporated beyond the essential 'core knowledge'.

This is the first international study of maternal care and maternal mortality. Over the last two hundred years, different countries developed quite different systems of maternal care. Death in Childbirth is a meticulously researched analysis, firmly grounded in the available statistics, of the evolution of those systems between 1800 and 1950 in Britain, the USA, Australia and New Zealand, and on the continent of Europe. Irvine Loudon examines the effectiveness of various forms of maternal care by means of the measurement of maternal mortality - the number of women who died as a result of childbirth. His scholarly and comprehensive study sets out to answer a number of important questions. What was the relative risk of a home or hospital delivery, or a delivery by a midwife as opposed to a doctor? What was the safest country in which to have a baby, and what were the factors which accounted for enormous international differences? Why, against all expectations, did maternal mortality fail to decline significantly until the late 1930s? Death in Childbirth makes an invaluable contribution to medical and social history.

It astounds the western world that such a highly industrialized nation as the Netherlands, with all the resources of modern medicine and technology, has a marked preference for home birth assisted by midwives. Van der Mark examines Dutch attitudes and practices surrounding birth from a sociohistorical point of view, explaining the importance of ideological consensus, the private nature of the Dutch family, the high regard for comfort and well being, and the professional development of midwives as trained and licensed practitioners. This volume will be welcomed by those convinced of the value of low-intervention home birth, but it will also be of interest to practitioners who must rely on technological procedures to manage the birth process. Since the Dutch hold one of the world records of pregnancy outcome statistics, readers will be interested in the Dutch midwifery model described here by various contributors.