1. Prologue.- 2. Is Estrogen A Cellular Signal for Female Genital Tract Epithelium?.- 3. Reciprocal Tissue Interactions in Morphogenesis and Hormonal Responsiveness of the Female Reproductive Tract.- 4. Qualitative and Quantitative Morphology of Induction in Endometrial Epithelium.- 5. Interactions of Estrogens, Protooncogenes and Growth Factors.- 6. Expression of Metallothionein Genes in Preimplantation Embryos, Decidua and Placentae.- 7. Uterine Preparation for Blastocyst Attachment.- 8. Uterine Extracellular Matrix Remodeling in Pregnancy.- 9. Glycoprotein Expression and Function in Embryo-Uterine Interactions.- 10. Uterine-Conceptus Interactions During the Peri-implantation Period.- 11. Endocrine Functions of the Rodent Placenta: Placental Lactogens.- 12. The Origin and Role of Cytokines Determining Success and Failure in the Post-implantation Period.- 13. Epilogue.- Poster Presentations.- Contributors.

This book aims to provide an up-to-date review of the literature in each of the major areas relating to the management of older gynecological cancer patients, and makes recommendations for best practice and future research. The authors come from a broad geographic spread including the UK, mainland Europe and North America to ensure a worldwide relevance.

Obstetrical emergencies can be among the most stressful events an emergency physician will face in their entire career. The purpose of this book is to provide an evidence-based, practical approach to the wide spectrum of obstetric complications an emergency physician must be prepared to manage throughout all trimesters pregnancy as well as postpartum, including complications of assisted reproductive technology, bleeding, precipitous delivery and preterm labor. Clinical pearls and pitfalls are highlighted throughout. The approach to the pregnant patient with trauma, non-pregnancy-related abdominal pain, or in cardiac arrest is discussed. Updates in the classification and management of the hypertensive disorders of pregnancy are presented. Recent controversies surrounding the use of anti-emetics for first trimester nausea and vomiting and the use of a beta-hCG discriminatory zone for the evaluation of pregnancy of unknown location are also addressed. Obstetrical support services vary widely between different facilities, and Emergency Department Management of Obstetric Complications is written for emergency clinicians in all practice settings. This book provides useful information for daily practice as well as preparation for rarely encountered and potentially life-threatening events.

In this issue of Obstetrics and Gynecology Clinics, Guest Editors Nathan Blue and Bob Silver bring their considerable expertise to the topic of Fetal Growth. Top experts in the field cover key topics such as placental function and physiology of fetal growth, fetal growth and stillbirth, fetal growth in multiple gestations, and more. Provides concise and comprehensive coverage of the issues physicians face every day. Presents the latest information on a timely, focused topic under the leadership of experienced editors in the field. Contains 12 relevant, practice-oriented topics including recurrence risk of FGR, fetal growth curves, diagnosis of FGR and LGA, routine third trimester sonograms, and more.

Practical guide to diagnosis and management of gynaecological emergencies Fully revised second edition featuring latest advances and many new topics Covers disorders in all age groups, from adolescence and puberty, to reproductive age and post-menopausal Includes discussion on ethical and medicolegal issues Highly illustrated with diagrams, flowcharts and tables

This volume examines one health issue -- breast implants -- across a series of contexts often thought to be separate -- media coverage, doctor-patient interaction, doctor-doctor professional communication, support group dialogues, public relations campaigns, and more. In so doing, it provides a narrative of how communication shapes the individual perceptions of health, government, and social policy concerning health care.
At the core of the silicone breast implant controversy is the need for people to act amid uncertainty about the health risks involved. This need to weigh action in the midst of uncertain risk characterizes a large number of health issues. The attempts of patients, physicians, drug manufacturers, and others to seek and provide both information and influence makes communication central to these issues. Consequently, the questions explored in this volume will interest a diverse group of readers. This audience includes plastic surgeons in particular, physicians in general, and anyone involved with women's health issues. As the medical profession struggles with its identity amid changes in public attitudes, government regulations, and medical practices, this volume's findings concerning media portrayals of doctors and medical devices become even more important.
Finally, this study reveals how interrelated public information and private decisions are, and how closely media and interpersonal relationships fit. Tracing one medical issue across interpersonal, organizational, public relations, and mediated forums has clearly demonstrated the multiple ways those communication channels overlap and inform one another.

Handbook of Obesity in Obstetrics and Gynecology addresses all aspects of general obstetrics and gynecology in obese patients, providing evidence-based guidance for the treatment and management of gynecological problems and pregnancy-related care in obese women. The book is a valuable resource for junior doctors, residents and obstetricians and gynecologists looking for a comprehensive guide that addresses the most relevant aspects of obstetric and gynecologic care that are impacted by obesity, an increasingly prevalent condition. The rising prevalence of global obesity is of public health concern, hence obese women suffer from a higher incidence of menstrual disorders, polycystic ovaries, infertility issues, and more. In pregnancy, obesity is associated with an increased risk of early pregnancy loss, recurrent pregnancy loss, fetal developmental abnormalities, thrombo-embolic disease, gestational diabetes, dysfunctional labor, post-partum hemorrhage and difficult operative deliveries.

This second edition of a groundbreaking book is substantially revised to deliver the foundation for an evidence-based model for best practices in midwifery a model critical to raising the United States current standing as the bottom-ranking country for maternity mortality among developed nations. With a focus on updated scientific evidence as the framework for midwifery practice, the book includes 21 completely new chapters that address both continuing and new areas of practice, the impact of institutional and national policies, and the effects of diversity and globalization. Incorporating the midwifery model of care, the book provides strategies for change and guidance for implementing evidence-based best practices. The book examines midwifery efforts to improve the health of women and children in the U.S., for example, Strong Start, US MERA, Centering Pregnancy, a focus on physiologic birth, and successful global endeavors. It encompasses a diverse nationwide authorship that includes leaders in midwifery, academicians, midwives representing diversity, hospital- and community-based practitioners, and policymakers. This coalition of authors from diverse backgrounds facilitates an engaging and robust discussion around best practices. Chapters open with a contemporary review of the literature, a comparison of current (often scientifically unsubstantiated and ineffective) practices, evidence-based recommendations, and best practices for midwifery. Key Features: Focuses on scientific evidence as the framework for midwifery practice Addresses continuing and new, controversial areas of practice with strategies and guidelines for change Includes 20 out of 27 completely new chapters Authored by a diverse group of 44 prominent midwifery leaders Examines practices that are in conflict with scientific evidence

This is a study of the work and life of district midwives from 1948 to 1972 in Nottingham, which was one of the last UK cities to build a central maternity unit. The author statistically examines the outcome of home births in the area, taking into account the Parliamentary Reports of 1992 and 1993 and demonstrating the safety and value to society of district midwives.

Consulting Editor, Dr. William Rayburn, is serving as Guest Editor for this special issue of Obstetrics and Gynecology Clinics devoted to Interprofessional Collaboration for Select Women's Health Issues. Articles deal with the spectrum of disciplines in response to failures of interprofessional collaboration that resulted in compromises to patient quality and safety. Systematic reviews have shown that this type of learning has led to positive outcomes in relation to participant's reactions, attitudes, knowledge/skill, behaviors, and practice, as well as patient benefits. Articles in this issue are specifically devoted to the following topics: Reproductive Rights and Women's Mental Health: Essential Information for the Ob/Gyn; Goals for Collaborative Management of Obstetric Hemorrhage; Role of Lipid Management in women's Health Preventative Care; Stroke in Pregnancy: An Update; Treatment of Viral Infections During Pregnancy; Benign Uterine Disease: The Added Role of Imaging; Racial Differences in Pregnancy-Related Morbidity and Mortality; Psychiatric Medication Use in Pregnancy and Breastfeeding; Neuroimaging During Pregnancy and the Postpartum Period; The Midlife Transition, Depression and Its Clinical Management; and Burnout in Obstetricians-Gynecologists: Its Prevalence, Identification, Prevention, and Reversal. Readers will come away with the information needed to improve patient outcomes while aiming toward goals like interprofessional faculty development that result in reducing feelings of isolation, developing a more collaborative approach, and providing opportunities to share knowledge, experiences, and ideas.

Nurse Barb provides a wealth of advice to guide readers through the hormonal roller coaster of menopause.

Representing the most relevant procedures and technologies aiding the advance of the field of HPV-mediated carcinogenesis of the cervix and other anatomical regions of squamocolumnar transition, such as the anorectum, penis, and oropharynx, Cervical Cancer: Methods and Protocols compiles a detailed collection of practical chapters. The first half of the book covers HPV types, pathogenesis of cervical cancer (CxCA), prevention, and novel potential drug targets, while the second half explores pathology, genomics, modeling of CxCA, and experimental therapeutic strategies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and vital, Cervical Cancer: Methods and Protocols serves as a valuable resource to both bench scientists and clinicians who step into the realm of high-risk HPVs and CxCA for the first time or those who wish to learn novel approaches or expand their toolbox for the study of CxCA.

Here is an informative book that provides theoretical perspectives on the study of fetal movement and introduces observational assessments that can be used in fetal research. It provides research tools that can be used to delineate early patterns of movement, preparing therapists for neonatal intervention and leading to a better understanding of functional activity of the fetus. Concepts in Fetal Movement Research describes various ideas in fetal development and contains original research on a variety of topics, including: the way in which events experienced in utero help neonatal interaction with parents inductive and deductive approaches to assessment development scapular movement activity/inactivity of the 12-20 week old fetus two different research tools for assessing fetal movement. future directions for research by physical therapists in collaboration with other researchersResearchers, clinicians, obstetricians, radiologists, sonographers, and neonatologists will all find this book full of helpful information. Concepts in Fetal Movement Research is an invaluable guide for both their research and their day-to-day work with patients.

This book is one woman's funny, moving, and sometimes awkward quest to fix her sex life, but it's the story of millions of women everywhere - half of all women have felt pain during sex. During award-winning writer and performer Fran Bushe's journey towards building a better relationship with her genitals, doctors advised her to have a glass of wine to loosen up, and male friends suggested she simply hadn't 'tried' the right penis yet. Unsurprisingly, neither worked. After a visit to Sex Camp and many attempts to fix her 'broken' vagina, Fran decided to share her own hilarious, excruciating, and sometimes upsetting experiences. With the help of her 16 year old self's diary, expert advice, candid and enlightening interviews with others about sex, and some self-care exercises, Fran sets about trying to make herself, and other people, feel like they're not being gaslit by their own vaginas.

Infectious diseases remain a major problem for physicians and other health professionals dealing with problems of the reproductive system. Accordingly, this two-volume comprehensive presentation of infectious diseases involving the male and female reproductive systems promises to be a major contribution in this field and to fill a much-needed vacuum. During the past three decades, the introduction of antimicrobial therapy has dramatically altered both the clinical presentation and the therapeutic approaches employed in dealing with the traditional infections of the repro ductive system. In addition, the changing demographics of infectious problems in the industrial countries and the developing world have been a source of concern. A good deal of important information on this topic is included in this series. In recent years, considerable attention has been given to the role of Myco plasma and Chlamydia in both male and female infertility and the problems related to genital herpes and human papilloma virus infections. Current clinical information is included on these infections as well as on newer aspects of diagnosis, such as the use of laparoscopy in the diagnosis and treatment of pelvic inflammatory disease. Also addressed is new information regarding the role of actinomycosis in pelvic infections; current problems such as toxic shock syndrome and acquired immune deficiency syndrome (AIDS) are reviewed as well. New concepts are included in these vohimes to complement the clinical information. The attachment of microbial organisms to sperm may help to explain access of these and other organisms to the upper female genital tract.

This text introduces readers to the diverse and unique ways art therapy is used with women who are undergoing various stages of the childbearing process, including conception, pregnancy, miscarriage, childbirth, and postpartum. Art Therapy and Childbearing Issues discusses a range of topics including the role of transference/countertransference, attachment and maternal tasks, and neuropsychology. The book also addresses several motifs that are outside cultural norms of pregnancy and childbearing, such as racial sociopolitical issues, grief and loss, palliative care, midwifery, menstruation, sex-trafficking, disadvantaged populations, and incarceration. Each chapter offers research, modalities, case studies and suggestions on how to work in this field in a new way, accompanied by visual representations of different therapy methods and practices. The approachable style will appeal to a range of readers who will come away with a new awareness of art therapy and a greater knowledge of how to work with women as they enter and exit this universal, psychobiological experience.

This book covers several aspects of perinatal tissue-derived stem cells, from theoretical concepts to clinical applications. Topics include functions and different sources, immunomodulatory properties, translational point of view, GMP facility design and manufacturing for clinical translation, therapeutic potentials, and finally ethical considerations. The text provides a brief review of each type of perinatal stem cells and then focuses on their multi- or pluripotent properties, regenerative capacity, and future therapeutic potential in regenerative medicine. Additionally, the book discusses GMP compliance in stem cell facilities and the manufacture of stem cells for clinical translation. The chapters are authored by world-renowned experts in the perinatal stem cell field. Perinatal Tissue-Derived Stem Cells: Alternative Sources of Fetal Stem Cells, part of Springer's Stem Cell Biology and Regenerative Medicine series, is essential reading for basic and clinical scientists, clinicians, and pharmaceutical experts working or conducting research in the fields of stem cell biology, molecular aspects of stem cell research, tissue engineering, regenerative medicine, and cellular therapy.

Breast MRI: State of the Art and Future Directions provides a comprehensive overview of the current applications of breast MRI, including abbreviated MRI, as well as presenting technical recommendations, practical implementation and associated challenges in clinical routine. In addition, the book introduces novel MRI techniques, multimodality imaging, and advanced image processing coupled with AI, reviewing their potential for impeding and future clinical implementation. This book is a complete reference on state-of-the-art breast MRI methods suitable for MRI researchers, radiographers and clinicians. Breast cancer is one of the leading causes of death among women with early detection being the key to improved prognosis and survival. Magnetic resonance imaging (MRI) of the breast is undisputedly the most sensitive imaging method to detect cancer, with a higher detection rate than mammography, digital breast tomosynthesis, and ultrasound.

Congenital malformations are worldwide occurrences, they know no national borders, do not distinguish between races, ethnicities, rich or poor. These severe physical abnormalities, present at birth, happen more often than is usually realized, once in every 33 births. They strike every part of the body, limbs, head, heart, and all others.

The most frequent of them all are the many types of malformations of the cardiovascular system, the heart and its blood vessels, which happen in about once in every 250 births. Study of these conditions during the twentieth century took many forms, revolving about examination and analysis of their causes, genetic, nongenetic, and complex. To aid in unraveling the complexities of this causation, various influences on their frequency are considered, among them social conditions, maternal health, birthweight, newborn maturity. And of course the known and possible environmental bases of their occurrence are fully described.
The relation of infant death to cardiovascular malformation is noted; and puzzlement that the level of such deaths had not kept pace with the reduction of infant death itself and of that associated with other kinds of malformations during this period.

An introductory record of the history of perinatal mortality in the last three centuries gives foundation for the discussion of death in contemporary decades.

This is the third volume on gastrointestinal cancer of the Cancer Treatment and Research Series. The emphasis in this volume is to present a series of papers on areas of high clinical relevance in malignant diseases of the gut. As in the first and second volumes of this series, authors have been selected for their expertise and national and international prominence in their fields. This volume is organized so that papers explaining basic science pro spec tives proceed those dealing with clinical aspects of gastrointestinal cancer. It is clear that in many instances advances gastrointestinal carcinoma cannot be effectively treated if ' cure' is the desired goal. When faced with poorly treatable diseases it is obviously important to look toward the causes and prevention of these illnesses. For this reason, there are several chapters in this volume that examine the issue of carcinogenesis of gastrointestinal cancer. Likewise, in diseases that are poorly treatable in advances stages, one is interested in early detection. Thus, early screening of populations becomes important and is dealt with in three papers in this volume. Chapt ers on treatment explore innovative approaches to therapy of gastrointesti nal cancer. Second-look surgery with resection, arterial perfusion with che motherapy, adjuvant therapy and neoadjuvant therapy are all addressed in various chapters in this volume. Finally, four chapters deal with unusual problems in gastrointestinal cancer. These papers include discussions ofpri mary hepatobillary cancer, lymphoma of the gut, and gastrointestinal endo crine tumors."

Progestogens are a class of steroid hormones that bind to and activate the progesterone receptor. This book is a guide to the use of progestogens for clinicians. Beginning with an overview of structure, biochemistry and classification, the following chapters discuss methods of administration, pharmacokinetics, metabolism and the physiological actions of progesterone. The remaining sections of the book cover clinical usage guidelines for progestogens, their role in contraception, side effects and contraindications. The book concludes with a chapter offering guidance on prescription writing and detailed references. Key points Guide to progestogens for obstetricians and gynaecologists Provides step by step detail on structure, classification, and pharmacokinetics Includes clinical usage guidelines, side effects and contraindications Features chapter on prescription writing

This contributed volume is the first-known collection of essays that brings together scholarly review, critiques, and primary and secondary data to assess how sociocultural factors influence health behavior in South Asian women. The essays are authored by working scholars or healthcare practitioners from Bangladesh, India, and Pakistan. In the chapters, the contributors acknowledge social, economic, and environmental factors to recommend improved interventions and health policy for women of the region. Studies on South Asian women's health have targeted clinical evidence, with less attention on social and environmental factors driving health recovery and health outcomes. The South Asian region, more than any other part of the world, is driven by traditional and cultural forces that are possibly the most significant factors determining a woman's health awareness and her rights to adopt healthy behavior or pursue health recovery. Women of the region share a common culture and political history, and there are benefits to understanding their problems collectively in order to design joint improvements in health policy for women. Salient, but neglected, socio-political areas that influence health behavior and health outcomes in women of the region are covered in the chapters including: Oral Narrations of Social Rejection Suffered by South Asian Women with Irreversible Health Conditions Women's Role in Decision-Making for Health Care in South Asia Poverty, Health Coverage, and Credit Opportunities for South Asian Women Refugee, Displaced, and Climate-Affected Women of South Asia and Their Health Challenges The Political Sociology of South Asian Women's Health The Sociology of South Asian Women's Health is a useful resource for students, researchers, and academicians, especially those interested in public health, gender, social policy, and occupational management, as well as healthcare practitioners, administrators, health and public policy-makers, government officers, and scholars of South Asian studies.