Genetic testing and genome sequencing have opened up the possibility to clinicians and families to treat diseases, syndromes, and malformations earlier and provide therapeutic interventions.The guest editors seek to provide a basic overview of the topic for the neonatologist/perinatologist. Articles addres dysmorphology, syndromes in the infant, skeletal dysplasias, limb malformations, craniofacial anomolies, GI/liver disease, disorders of sexual develoment, brain defects, inborn errors of metabolism, and congenital heart disease.

There have been exciting new developments and research related to currently available contraceptives. In addition, in the last seven years, emergency contraception has gone from behind the counter to being FDA-approved for use. This issue addresses the most important clinical leaps in contraception and family planning in the last decade, with emphasis on new options for long-term, reversible contraception and emergency contraception. Information is also included to address the impact of Affordable Health Care and legal aspects of sterilization.

The Guests Editors have assembled expert authors to present clinical reviews on the current knowledge and best practices for high-risk pregnancies. Authors are writing on Genetics: update on prenatal screening and diagnosis; Screening for congenital heart disease; What you need to know when managing twins; Short cervix dilemma; preterm labor: approach to decreasing complications of prematurity; Optimizing outcomes for the growth-restricted fetus; Preeclampsia: short- and long-term implications; pregnancy risk associated with obesity; prevention of first cesarean delivery, and diagnosis and management of placenta accreta.

PART 1 OBSTETRICS SECTION 1 REPRODUCTIVE BASICS SECTION 2 PRE-PREGNANCY SECTION 3 EARLY ANTENATAL SECTION 4 LATE ANTENATAL--MATERNAL-MEDICAL DISORDERS SECTION 5 LATE ANTENATAL--MATERNAL-GENERAL SECTION 6 LATE ANTENATAL--FETAL SECTION 7 LABOR SECTION 8 POSTPARTUM SECTION 9 OPERATIVE OBSTETRICS PART 2 GYNECOLOGY SECTION 10 BASICS IN GYNECOLOGY SECTION 11 GYNECOLOGIC PROCEDURES SECTION 12 UROGYNECOLOGY SECTION 13 DISORDERS OF MENSTRUATION AND PUBERTY SECTION 14 INFERTILITY SECTION 15 BENIGN GYNECOLOGICAL DISORDERS SECTION 16 REPRODUCTIVE TRACT INFECTIONS SECTION 17 GYNECOLOGIC ONCOLOGY SECTION 18 GENERAL GYNECOLOGY SECTION 19 CONTRACEPTION PART 3 EXAM PREPARATION SECTION 20 OBSTETRICS SECTION 21 GYNECOLOGY SECTION 22 INSTRUMENTS SECTION 23 DRUGS SECTION 24 SPECIMENS SECTION 25 CTG, PARTOGRAM, X-RAY, USG, ETC.

A high-risk pregnancy is one in which a woman and her foetus face a higher-than-normal chance of experiencing problems. These risks may be due to factors in the pregnancy itself, or they may stem from pre-existing maternal medical conditions. This book is a comprehensive guide to the management of high risk pregnancies for postgraduate medical students. It is an amalgamation of existing literature, current guidelines, and recent advances in medical technologies. Divided into 22 chapters, the text covers pathophysiology, systematic investigations, diagnosis, and appropriate management for both maternal and foetal disorders, helping trainees identify conditions that can make a pregnancy high risk. The book is highly illustrated with clinical images, diagrams and flowcharts, and features a question paper and extensive bibliography to assist learning.

Given that millions of women have entered menopause each year since the dawn of time, it's bizarre that it still feels like uncharted territory for the women who are going through it. Dr. Heather Hirsch is committed to changing that. Unlock Your Menopause Type helps women cut through the informational noise and learn how to manage their symptoms most effectively by identifying their personal Menopause Type(s). This is not a one-size fits all solution. Unlock Your Menopause Type features a helpful quiz to identify women's individual Menopause Type(s) such as: -Premature -Sudden -Full-Throttle -Mind-Altering -Seemingly Never-ending -Silent Each type gets a full prescription for exercises, diet and strategies to regain mental focus and make menopause a routine part of maturity rather than a rollercoaster ride of unexpected symptoms and discomfort. The book also includes: -The last word on whether to replace declining hormones -What to do if you're a combination of types -How to get on top of (as it were) changes in your sex life -Crowd-sourced tips and tricks from Dr Hirsch's friend group and patients Dr Hirsch addresses the physical and emotional challenges of menopause and provides solutions from her years of practice. With knowledge, priorities and a plan, you can feel great through midlife and beyond.

This issue of Obstetrics and Gynecology Clinics of North America provides a summary of several more common maternal-fetal-infant infectious diseases. Several experts in the field of maternal and perinatal infection have contributed to this issue to provide an overview of the up-to-date preventive strategies, screening and diagnostic methods, and treatment guidelines. While guidelines such as universal vaccination to prevent influenza during pregnancy are fairly well justified by supporting data, there is much uncertainty about the appropriate screening guidelines for conditions such as cytomegalovirus, where the lack of a proven effective treatment diminishes the value of screening. Moreover, increasing issues of antibiotic resistance and the lack of significant advancement in developing newer effective agents imply that both providers and health care facilities must follow guidelines of antimicrobial stewardship (ie, coordinated efforts to improve and measure the appropriate use of antimicrobials). It is our hope that this issue will aid providers in navigating these complex issues while also understanding the current state-of-the-science

Neonatal-perinatal medicine has a strong history of evidence based practice but unfortunately there remain many areas of uncertainty and unproven hypotheses and treatments that may harm our highly vulnerable patients. When new ideas are introduced into the labor and delivery room or the NICU we have to evaluate these procedures and therapies before they become accepted as standards of care. We need to learn from the past lessons of grey baby syndrome and chloramphenicol and of kernicterus and sulfonamide antibiotics where therapeutic good intentions actually did more harm than good and increased the mortality rate of premature babies in the NICU.This proposed edition addresses a broad range of current topics in perinatal neonatal practice. The AAP has just issued new guidelines for the approach to a neonate exposed to maternal genital herpes virus infection. The recommendations were not evidence based and are highly controversial as well as confusing. These topics are addressed in a scholarly and objective manner to both address the controversy and help the practitioner make informed decisions.

This issue of Medical Clinics of North America, Guest Edited by Joyce E. Wipf , MD is devoted to Women's Health. Dr. Wipf has assembled a group of expert authors to review the following topics: Breast Cancer Screening; Cervical Cancer and HPV; Oral Contraception; IUD and Other Contraception; Menopause; Cardiovascular Risk Factors and Disease in Women; Vulvar-vaginal Disorders; Hepatitis C in Women; Osteoporosis Screening, Prevention, and Management; Sexual Dysfunction in Women; Domestic Violence and Trauma; Care of Women Veterans; and Medical Conditions During Pregnancy.

Healthy Babies Are Worth the Wait (R): A Collaborative Partnership to Reduce Preterm Births in Kentucky through Community-based Interventions 2007 - 2009 provides readers with an overview of the problem of preterm birth in the US, also describing in detail the design, implementation, evaluation, and outcomes of the Healthy Babies Are Worth the Wait initiative conducted in Kentucky between 2007 and 2009. The reader will learn about a unique research approach employing a mixed ecologic design that compared outcomes between intervention sites and comparison sites and the use of qualitative surveys and quantitative methods using state vital records data to evaluate outcomes. Consumer messaging and educational materials are discussed, along with the challenges of implementation and key lessons learned.

This issue of Obstetrics and Gynecology Clinics of North America attempts to provide an overview of the more common causes of chronic pelvic pain in women. It brings together experts in various fields of gynecology, gastroenterology, physical therapy, and urogynecology in an attempt to discuss the wide variety of common clinical conditions that can manifest as pain. The intent is to enable the physician to consider not only the common gynecologic causes but also the common nongynecologic causes based on certain symptom profiles and targeted clinical examination. Should the physician not feel comfortable in treating the nongynecologic causes, it would enable them to target their referral to a more appropriate physician rather than the patient being referred back to a general primary care physician. It is our hope that it will enable the reader to see the pelvis not as an ovary or a uterus but as a whole system of interacting organs, muscles, and nerves. In addtiion, there is very little in the Obstetrics and Gynecology literature about the treatment of the pain component with opioid and nonopioid medications. As one of my colleagues frequently states, we can treat the pain but not necessarily alleviate the suffering. The overview of complementary and alternative medications and opioid use will hopefully be useful to the practicing physician as it provides an evidence-based approach to the use of these therapies specifically for chronic pelvic pain.

Breast Disease: Comprehensive Management provides a clear, concise source of information in order to make real-life, evidence-based decisions for all aspects of breast disease, both benign and malignant. The volume provides the latest breakthroughs in breast cancer research, ranging from paradigm shifts in the surgical management of the axilla, the changing role of adjuvant and neoadjuvant chemotherapy, the impact of molecular medicine in decision-making and the controversial role of prophylactic mastectomy in our era. Within select chapters, "How I do it" clinical scenarios are supplied and described in very practical terms. Also included at the end of each chapter are synoptic questions with detailed answers, akin to the self-assessment (SESAP) format questions and answers. These questions provide a basis for continuous medical education (CME) for the practicing physician and surgeon, further in surgical oncology and breast surgery, medical oncologists, radiation oncologists, and breast radiologists enhancing a focused approach to the management of breast disease in preparation for the American Board of Surgery certification and re-certification for the general surgeon. Breast Disease: Comprehensive Management is of great value to general surgeons, breast surgeons, surgical oncologists, general surgery residents, and fellows.

This atlas is a practical guide to the role of ultrasound in the diagnosis of foetal anomalies. The second edition has been fully revised and new topics added, to provide clinicians with the latest advances in the field. Beginning with an overview of ultrasound and foetal anomalies, each of the following sections covers a different type of foetal disorder, from the most common to the most serious, including face malformations, skeletal dysplasias, congenital heart and lung conditions, brain structure and central nervous system anomalies, and many more. The text draws on the experience of internationally recognised experts in the field, led by renowned editors from Bosnia-Herzegovina, Japan, and the USA. A multitude of foetal ultrasound images and figures further enhance this comprehensive guide. The previous edition (9788180619199) published in 2007.

Kidney anomalies are the most frequent abnormality detected on prenatal ultrasound. Some are inconsequential and others are life-threatening. All must be addressed by neonatologists. This edition of Pediatric Clinics of Perinatology covers these anomalies. In addition, it addresses a variety of other nephrology and urology issues that neonatologists confront. Some are rare and the chapter may then serve as an important resource. Others are common, and thus will provide updated information on diagnosis and management.

Despite the wide prevalence of urogynaecological problems, in clinical practice, there is a paucity of specialists that are skilled in the management of these conditions. The recognition of the need for a specialist to deal with these specific problems has led to the recent evolution of urogynaecology as a subspecialty. This book, Principles and Practice of Urogynaecology aims to equip the practicing professionals - Gynaecologists, Urogynaecologists and Urologists, with up-to-date information on the principles that guide the evaluation and management of pelvic organ prolapse and other common urogynaecological problems. With an emphasis on evidence based medicine, the book aims to deliver guidance on management of common urogynaecological problems and provides information on the latest cutting-edge surgical techniques. Written by global experts in the field of urogynaecology, the book focuses initially on pelvic floor anatomy and function, moving seamlessly to the evaluation and management of clinically relevant pelvic floor problems. A detailed discussion on management of mesh related complications is a highlight.

This issue of Obstetrics and Gynecology Clinics of North America deals with the timely subject of substance use during pregnancy. Alcohol, tobacco, and illicit drug use is prevalent among reproductive-age women. Even though a reduction in use often occurs during pregnancy, many women continue to use substances until a pregnancy is either actually diagnosed or well underway.This issue consists of a well-qualified team of obstetricians-gynecologists, psychiatrists, and family physicians, focusing on various issues related directly to pregnancies complicated by substance use. Topics of interest include epidemiology and screening for hazardous and harmful substance use, teratogenic risks, psychiatric comorbidities, comprehensive treatment approaches before and after delivery, fetal surveillance, and team-based perinatal management. Particularly new information relates to prescribing buprenorphine, neonatal abstinence syndrome, and adolescent substance use.

This issue of the Obstetrics and Gynecology Clinics in North America will focus on the advances in the evaluation and management of Recurrent Pregnancy Loss (RPL) that have emerged within the last few years. Although spontaneous pregnancy loss occurs in approximately 15% to 20% of clinically recognized pregnancies in reproductive-aged women, RPL occurs in 2% to 5% of the same population. Recent reports on large populations of women with RPL have helped to characterize the incidence and diversity of this heterogeneous disorder, and a definite cause of pregnancy loss can be established on over 50% of all couples after a thorough evaluation. New diagnostic strategies, which include 23-chromosome microarray genetic testing of the products of conception in failed pregnancies, offer the promise of understanding the cause of most pregnancy losses. These recent advances, combined with the contributions from the authors in this issue of Clinics and many others interested in this field, lead to the publication of the long-awaited publication on evaluation and treatment of RPL from the Practice Committee of the American Society for Reproductive Medicine. A complete evaluation will include investigations into genetic, anatomic, immunologic, endocrinologic, and iatrogenic factors. "Generally the book is well written by internationally recognized and dedicated specialists, informative, updated and well-illustrated. I can recommend this book for physicians, scientists and also interested medical students who want to understand more about high risk early pregnancy." Reviewed by: Acta Obstetricia et Gynecologica Scandinavica, January 2015

Guest edited by Christopher Comstock of Memorial Sloan-Kettering, this issue of Radiologic Clinics will provide all of the latest guidelines and techniques for breast imaging. Modalities include MRI, MR-CAD, digital tomosynthesis, and ultrasound.