Healthy Babies Are Worth the Wait (R): A Collaborative Partnership to Reduce Preterm Births in Kentucky through Community-based Interventions 2007 - 2009 provides readers with an overview of the problem of preterm birth in the US, also describing in detail the design, implementation, evaluation, and outcomes of the Healthy Babies Are Worth the Wait initiative conducted in Kentucky between 2007 and 2009. The reader will learn about a unique research approach employing a mixed ecologic design that compared outcomes between intervention sites and comparison sites and the use of qualitative surveys and quantitative methods using state vital records data to evaluate outcomes. Consumer messaging and educational materials are discussed, along with the challenges of implementation and key lessons learned.

This text provides a comprehensive, state-of-the art review of pharmacotherapy for the overactive bladder, and serve as a valuable resource forclinicians, surgeons, and researchers with an interest in OAB. The early chapters will describe the pathophysiology of OAB, algorithm, and provide the readers with a practical guide for evaluating the OAB patient. The next section describes the unique challenges involved in the study of OAB and helps the reader navigate the complexities of the literature on the topic. All chapters are written by experts in their fields and include the most up-to-date scientific and clinical information. The text includes a review of the clinical guidelines for OAB, and a detailed description of the individual therapies, including antimuscarinics, Beta-3 agonists, (insert comma) and chemodenervation. Extensive tabulation of contemporary literature makes this a matchless resource that provides a detailed account of the current evidence for the use of each of these therapies. The text concludes with chapters on unique populations with OAB, and future directions in the research field.Contemporary Pharmacotherapy of Overactive Bladder unites a unique set of thought leaders in the field of voiding dysfunction to create a comprehensive resource that will be useful for a variety of clinicians who treat OAB, including urologists, urogynecologists, general gynecologists, family practitioners, and geriatricians.

Genetic testing and genome sequencing have opened up the possibility to clinicians and families to treat diseases, syndromes, and malformations earlier and provide therapeutic interventions.The guest editors seek to provide a basic overview of the topic for the neonatologist/perinatologist. Articles addres dysmorphology, syndromes in the infant, skeletal dysplasias, limb malformations, craniofacial anomolies, GI/liver disease, disorders of sexual develoment, brain defects, inborn errors of metabolism, and congenital heart disease.

This issue of Medical Clinics of North America, Guest Edited by Joyce E. Wipf , MD is devoted to Women's Health. Dr. Wipf has assembled a group of expert authors to review the following topics: Breast Cancer Screening; Cervical Cancer and HPV; Oral Contraception; IUD and Other Contraception; Menopause; Cardiovascular Risk Factors and Disease in Women; Vulvar-vaginal Disorders; Hepatitis C in Women; Osteoporosis Screening, Prevention, and Management; Sexual Dysfunction in Women; Domestic Violence and Trauma; Care of Women Veterans; and Medical Conditions During Pregnancy.

Breast Disease: Comprehensive Management provides a clear, concise source of information in order to make real-life, evidence-based decisions for all aspects of breast disease, both benign and malignant. The volume provides the latest breakthroughs in breast cancer research, ranging from paradigm shifts in the surgical management of the axilla, the changing role of adjuvant and neoadjuvant chemotherapy, the impact of molecular medicine in decision-making and the controversial role of prophylactic mastectomy in our era. Within select chapters, "How I do it" clinical scenarios are supplied and described in very practical terms. Also included at the end of each chapter are synoptic questions with detailed answers, akin to the self-assessment (SESAP) format questions and answers. These questions provide a basis for continuous medical education (CME) for the practicing physician and surgeon, further in surgical oncology and breast surgery, medical oncologists, radiation oncologists, and breast radiologists enhancing a focused approach to the management of breast disease in preparation for the American Board of Surgery certification and re-certification for the general surgeon. Breast Disease: Comprehensive Management is of great value to general surgeons, breast surgeons, surgical oncologists, general surgery residents, and fellows.

This issue of Obstetrics and Gynecology Clinics of North America provides a summary of several more common maternal-fetal-infant infectious diseases. Several experts in the field of maternal and perinatal infection have contributed to this issue to provide an overview of the up-to-date preventive strategies, screening and diagnostic methods, and treatment guidelines. While guidelines such as universal vaccination to prevent influenza during pregnancy are fairly well justified by supporting data, there is much uncertainty about the appropriate screening guidelines for conditions such as cytomegalovirus, where the lack of a proven effective treatment diminishes the value of screening. Moreover, increasing issues of antibiotic resistance and the lack of significant advancement in developing newer effective agents imply that both providers and health care facilities must follow guidelines of antimicrobial stewardship (ie, coordinated efforts to improve and measure the appropriate use of antimicrobials). It is our hope that this issue will aid providers in navigating these complex issues while also understanding the current state-of-the-science

Neonatal-perinatal medicine has a strong history of evidence based practice but unfortunately there remain many areas of uncertainty and unproven hypotheses and treatments that may harm our highly vulnerable patients. When new ideas are introduced into the labor and delivery room or the NICU we have to evaluate these procedures and therapies before they become accepted as standards of care. We need to learn from the past lessons of grey baby syndrome and chloramphenicol and of kernicterus and sulfonamide antibiotics where therapeutic good intentions actually did more harm than good and increased the mortality rate of premature babies in the NICU.This proposed edition addresses a broad range of current topics in perinatal neonatal practice. The AAP has just issued new guidelines for the approach to a neonate exposed to maternal genital herpes virus infection. The recommendations were not evidence based and are highly controversial as well as confusing. These topics are addressed in a scholarly and objective manner to both address the controversy and help the practitioner make informed decisions.

Despite the wide prevalence of urogynaecological problems, in clinical practice, there is a paucity of specialists that are skilled in the management of these conditions. The recognition of the need for a specialist to deal with these specific problems has led to the recent evolution of urogynaecology as a subspecialty. This book, Principles and Practice of Urogynaecology aims to equip the practicing professionals - Gynaecologists, Urogynaecologists and Urologists, with up-to-date information on the principles that guide the evaluation and management of pelvic organ prolapse and other common urogynaecological problems. With an emphasis on evidence based medicine, the book aims to deliver guidance on management of common urogynaecological problems and provides information on the latest cutting-edge surgical techniques. Written by global experts in the field of urogynaecology, the book focuses initially on pelvic floor anatomy and function, moving seamlessly to the evaluation and management of clinically relevant pelvic floor problems. A detailed discussion on management of mesh related complications is a highlight.

The manual provides a complete overview of the clinical assessment, diagnosis and rehabilitation of pelvic floor dysfunctions. The book will help physical therapist students, practicing physical therapists or medical professionals to reinvent the world of pelvic floor rehabilitation with needful details about the anatomy, physiology, causes of pelvic floor dysfunctions, associated pathologies, types of pelvic floor muscle dysfunctions and sexual dysfunction in female and male along with different pelvic floor dysfunctions in female, male and pediatric population. This book also mentions different efficient techniques of pelvic floor evaluation, methodologies and treatment options for common pelvic floor muscles condition. A complete overview of functional anatomy, dysfunctions, causes, types of dysfunctions (hypertonus, hypotonus, incoordination, visceral), clinical assessment, diagnosis and rehabilitation of pelvic floor conditions in female, male and children. Evaluation and rehabilitation for conditions like vaginal laxity, urinary incontinence (stress urinary incontinence, urge urinary incontinence and mixed incontinence), pelvic organ prolapse, sexual dysfunction, pelvic pain, endometriosis, interstitial cystitis, vaginismus and dyspareunia in female. Evaluation and rehabilitation for conditions like erectile dysfunction, premature ejaculation, postvoidal dribbling, prostatitis, postprostatectomy rehabilitation and pelvic pain in male have been discussed. Evaluation and rehabilitation for conditions like enuresis and encopresis in children. Het's MMT, Het's SERF Assessment, Het's Ring Clock Assessment, Het's RR Scale and HPP guidelines. Most simplified practical approach to noninvasive, transvaginal and transrectal evaluation and rehab. Functioning of multiple types of biofeedback and rehabilitation devices like ultimate noninvasive, smart and extremely efficient technology PF360 for urogenital/urogynec/ anorectal rehabilitation. Basics of medical and surgical management of conditions related to pelvic floor dysfunctions.

This issue of Obstetrics and Gynecology Clinics of North America attempts to provide an overview of the more common causes of chronic pelvic pain in women. It brings together experts in various fields of gynecology, gastroenterology, physical therapy, and urogynecology in an attempt to discuss the wide variety of common clinical conditions that can manifest as pain. The intent is to enable the physician to consider not only the common gynecologic causes but also the common nongynecologic causes based on certain symptom profiles and targeted clinical examination. Should the physician not feel comfortable in treating the nongynecologic causes, it would enable them to target their referral to a more appropriate physician rather than the patient being referred back to a general primary care physician. It is our hope that it will enable the reader to see the pelvis not as an ovary or a uterus but as a whole system of interacting organs, muscles, and nerves. In addtiion, there is very little in the Obstetrics and Gynecology literature about the treatment of the pain component with opioid and nonopioid medications. As one of my colleagues frequently states, we can treat the pain but not necessarily alleviate the suffering. The overview of complementary and alternative medications and opioid use will hopefully be useful to the practicing physician as it provides an evidence-based approach to the use of these therapies specifically for chronic pelvic pain.

Kidney anomalies are the most frequent abnormality detected on prenatal ultrasound. Some are inconsequential and others are life-threatening. All must be addressed by neonatologists. This edition of Pediatric Clinics of Perinatology covers these anomalies. In addition, it addresses a variety of other nephrology and urology issues that neonatologists confront. Some are rare and the chapter may then serve as an important resource. Others are common, and thus will provide updated information on diagnosis and management.

This book reveals the structures of poverty, power, patriarchy and imperialistic health policies that underpin what the World Health Organization calls the "hidden disease" of vaginal fistulas in Africa. By employing critical feminist and post-colonial perspectives, it shows how "leaking black female bodies" are constructed, ranked, stratified and marginalised in global maternal health care, and explains why women in Africa are at risk of developing vaginal fistulas and then having adequate treatment delayed or denied. Drawing on face-to-face, in-depth interviews with 30 Kenyan women, it paints a rare social portrait of the heartbreaking challenges for Kenyan women living with this most profound gender-related health issue - an experience of shame, taboo and abjection with severe implications for women's wellbeing, health and sexuality. In absolutely groundbreaking depth, this book shows why research on vaginal fistulas must incorporate feminist understandings of bodily experience to inform future practices and knowledge.

This volume is the proceedings of the International Symposium on Male Sterility for Motility Disorders, held in Paris, January 30-31, 1998. The internationally recognized faculty present the latest research on etiologic factors and treatment of male sterility for motility disorders, including the etiology of immobile sperm; therapeutic possibilities for immotile sperm; ICSI option; testicular sperm, physiological and pathological aspects and retrieval; and conceptus quality in ICSI and ethical problems with ART.

Viewed from a scientific historical angle, perinatal medicine is a still young special interdisciplinary field of medicine which came into being during the middle of the 20th century. Thanks to the scientific and medical activities of one of the editors of this volume, Professor Erich Saling, who is also called "The Father of Perinatal Medicine", essential impulses and innovations were achieved. With the introduction of fetal blood analysis he made it possible to gain access to the unborn infant, which today is regarded as a milestone at the beginning of Perinatal Medicine. For the first time, human medicine entered the intrauterine space. With the exception of the collection of articles by Rooth and Saugstad published in 1985, in the history of perinatal medicine there only exist single papers of various sub-disciplines (for example fetal surveillance sub partu, ultrasonography) either as an article in a magazine, or as a chapter in an appropriate text book. Up to now there has been no publication that presents in an integrative way the history of the still young speciality. The main emphasis will be on the time period up to the early 70s (that means the early stages of Perinatal Medicine), however, both scientific precursors and later developments are mentioned shortly, when opportune. The authors of this volume are qualified specialists and some of them have decades of experience in the field they describe.

My HalfLife in Teratology-As it Relates to the Origins of Cancer (R.W. Miller). Intergenerational Factors in Pregnancy Outcomes (I. Emanuel). Epidemiological Studies of Congenital Abnormalities in Hungary (A. Czeizel). A Contemporary Overview of Behavioral Teratology (D.E. Hutchings). Do Thresholds Exist for Developmental Toxicants? (G.P. Daston). The History of His Life and Career (E. Wolff). Index.

This issue of Obstetrics and Gynecology Clinics of North America deals with the timely subject of substance use during pregnancy. Alcohol, tobacco, and illicit drug use is prevalent among reproductive-age women. Even though a reduction in use often occurs during pregnancy, many women continue to use substances until a pregnancy is either actually diagnosed or well underway.This issue consists of a well-qualified team of obstetricians-gynecologists, psychiatrists, and family physicians, focusing on various issues related directly to pregnancies complicated by substance use. Topics of interest include epidemiology and screening for hazardous and harmful substance use, teratogenic risks, psychiatric comorbidities, comprehensive treatment approaches before and after delivery, fetal surveillance, and team-based perinatal management. Particularly new information relates to prescribing buprenorphine, neonatal abstinence syndrome, and adolescent substance use.

Guest edited by Christopher Comstock of Memorial Sloan-Kettering, this issue of Radiologic Clinics will provide all of the latest guidelines and techniques for breast imaging. Modalities include MRI, MR-CAD, digital tomosynthesis, and ultrasound.

One out of every three women age 18-45 has experienced a reproductive loss. Women experiencing miscarriage often receive no explanation for the cause of their miscarriage. The lack of advice regarding the future and what can be done to avoid another miscarriage is too often the case.

"Miscarriage and the Successful Pregnancy" will provide insights and answers regarding miscarriage. William P. Hummel, M.D., a nationally recognized Fertility Specialist, states "A significant number of miscarriages can be prevented. A thorough fertility evaluation should give all couples options to maximize a full term pregnancy."

"Miscarriage and the Successful Pregnancy" provides the psychological support of this devastating condition and offers constructive steps to take with your physician. It is the authoritative guide to miscarriage treatment and success of your next pregnancy.

The authors address in particular the role of hormones and their links with other maternal environmental mediators in developmental programming. The crucial nature of the placenta as an interface and target between maternal and foetal environments is addressed. Emphasis is made on the emerging science of epigenetics as a potential explanation for how environmental events that occur during brief windows of development may exert effects that impact upon somatic cells through many rounds of mitosis for much of the life span of the subsequent organism.

For pelvic symptoms, ultrasound is the initial imaging modality of choice in today s cost-conscious climate. Employing a practical, problem-based approach Gynecologic Ultrasound is the only medical reference that provides a stepwise method in the diagnosis of gynecological abnormalities. Abundantly illustrated and easily accessible, it is an ideal resource for a clinical setting. "...an excellent text, well-illustrated and well worth having in any library." Reviewed by RAD Magazine, Dec 2014 Expedite and confirm diagnosis of gynecological abnormalities. An easily accessible format-organized by both entity and differential diagnosis-facilitates searches and zeroing in on the one correct entity. Master the nuances of using ultrasound through the visual instruction of more than 600 clear images including 3D and Doppler - important and necessary tools for pelvic ultrasound. Glean all essential, up-to-date, need-to-know information about Mullerian Duct Abnormality, Endometriosis, Ovarian cancer, and Uterine Sarcoma as well as normal pelvic ultrasound and common normal variants. Consult this reference where and when you need it at Expert Consult.

This issue of the Obstetrics and Gynecology Clinics in North America will focus on the advances in the evaluation and management of Recurrent Pregnancy Loss (RPL) that have emerged within the last few years. Although spontaneous pregnancy loss occurs in approximately 15% to 20% of clinically recognized pregnancies in reproductive-aged women, RPL occurs in 2% to 5% of the same population. Recent reports on large populations of women with RPL have helped to characterize the incidence and diversity of this heterogeneous disorder, and a definite cause of pregnancy loss can be established on over 50% of all couples after a thorough evaluation. New diagnostic strategies, which include 23-chromosome microarray genetic testing of the products of conception in failed pregnancies, offer the promise of understanding the cause of most pregnancy losses. These recent advances, combined with the contributions from the authors in this issue of Clinics and many others interested in this field, lead to the publication of the long-awaited publication on evaluation and treatment of RPL from the Practice Committee of the American Society for Reproductive Medicine. A complete evaluation will include investigations into genetic, anatomic, immunologic, endocrinologic, and iatrogenic factors. "Generally the book is well written by internationally recognized and dedicated specialists, informative, updated and well-illustrated. I can recommend this book for physicians, scientists and also interested medical students who want to understand more about high risk early pregnancy." Reviewed by: Acta Obstetricia et Gynecologica Scandinavica, January 2015