In this issue of Obstetrics and Gynecology Clinics of North America, guest editors Drs. Henry Galan and Patricia Huguelet bring their considerable expertise to the topic of Emergencies in Obstetrics and Gynecology. This issue provides a comprehensive overview of obstetric and gynecologic emergencies, with emphasis on standards of practice and interdisciplinary collaboration. Expert authors discuss how to arrive at a differential diagnosis and how to prevent, manage, and treat an emergency. Contains 15 practice-oriented topics including hypertensive crisis in pregnancy; sexual assault/domestic violence; evaluation and management of heavy vaginal bleeding (non-cancerous); first trimester miscarriage; simulation in Ob/Gyn emergencies; and more. Provides in-depth clinical reviews on emergencies in obstetrics and gynecology, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Translational Advances in Gynecologic Cancers straddles the bench and bed divide by highlighting important and interesting research that is translatable to the clinic. The contents of this book cover the entire spectrum, from promising laboratory based research, to clinical trial efforts. Further, new therapeutic indications based upon randomized phase III trials are also included. Clinicians will learn about lab-based science that is about to enter the clinic, along with the rationale behind translational endpoints in trials. Researchers will be able to identify and understand the clinical needs of patients with these types of tumors to improve their research focus.

Biomechanics of the Female Pelvic Floor, Second Edition, is the first book to specifically focus on this key part of women's health, combining engineering and clinical expertise. This edited collection will help readers understand the risk factors for pelvic floor dysfunction, the mechanisms of childbirth related injury, and how to design intrapartum preventative strategies, optimal repair techniques, and prostheses. The authors have combined their expertise to create a thorough, comprehensive view of female pelvic floor biomechanics in order to help different disciplines discuss, research, and drive solutions to pressing problems. The book includes a common language for the design, conduct, and reporting of research studies in female PFD, and will be of interest to biomechanical and prosthetic tissue engineers and clinicians interested in female pelvic floor dysfunction, including urologists, urogynecologists, maternal fetal medicine specialists, and physical therapists.

Complications during and after pregnancy and birth result in hundreds of thousands of deaths each year and can lead to lifelong health problems. Even with these complications, however, early detection and prenatal care can further reduce risk to the mother and baby. However, inadequate medical services, shortage of medical resources, and lack of or misinformation can hinder a woman's ability to successfully manage her pregnancy. This not only affects the health of the people immediately concerned and their families, but also has implications for global stability and the balance between population and resources. Evaluation and Management of High-Risk Pregnancies: Emerging Research and Opportunities is a pivotal reference source that provides vital research on safeguarding mothers and babies through the availability of medical knowledge, cost-effective interventions, and the availability of widespread obstetric services. While highlighting topics such as labor complications, maternal mortality, and reproductive health, this publication explores exposure to sexually transmitted diseases as well as the methods of physical and mental healthcare. This book is ideally designed for obstetricians, gynecologists, world health organizations, policymakers, hospitals, health professionals, reproduction researchers, and physicians.

Overcoming Drug Resistance in Gynecologic Cancers provides up-to-date information related to important gynecologic cancers and focuses on mechanisms of drug resistance, genetics, signaling, immunology, health disparities, nanotechnology, economic considerations and financial impacts. The book covers not only drug resistance but also important means to reverse resistance both in the laboratory and clinic. The book discusses topics such as lifestyle, nutrition and risk of gynecologic cancers, the financial impact of drug resistance, chemosensitizing agents and targeted therapies in cervical, endometrial and ovarian cancer, immunotherapy to overcome drug resistance, and genetic polymorphisms in gynecologic cancers. Additionally, it discusses ethnic and racial health disparity perspectives and future developments in chemosensitizing activities to reverse drug resistance in gynecologic cancers. It is a valuable resource for cancer researchers, oncologists, clinicians and other biomedical field members who are interested in new approaches to improve chemotherapy outcome in patients with gynecologic cancers.

This book highlights both conventional and nanomaterials-based biosensors for the detection of cervical cancers. It describes developments in the selective and sensitive electrochemical biosensors based on DNA for the early diagnosis of cervical cancer. Further, this book covers other nano-biosensing systems such as nano-thermometry-based sensing platforms, mechanical sensing platforms encompassing piezoelectric-based sensors, electrochemical impedance spectroscopy based on PEGylated arginine functionalized magnetic nanoparticles, and field-effect transistor-based platforms for the early detection of cervical cancer. Also, it presents conventional platforms such as vibrational spectroscopy and polymerase chain reaction techniques for the diagnosis of cervical cancer. Finally, it reviews currently available biomarkers for the early diagnosis of cervical cancer and presents strategies for developing novel biomarkers based on cellular and molecular approaches. As such, this book is a comprehensive resource for researchers and clinicians working in cervical cancer diagnostics.

The subspecialty of Obstetric Medicine sits in a unique intersection of the disciplines of Internal Medicine and Obstetrics. Its focus is in the skilled management of medical problems in pregnancy: from pre-pregnancy optimization to the management of acute and chronic conditions in pregnancy, and in the postpartum period to ensure resolution and safe transition back to the primary care provider. This book will provide novel insights into the management of pregnant women. Clinical pearls will be emphasized, such as illustrating atypical aspects of a presenting symptom/finding, and when a subspecialty referral (or transfer to a high risk centre) must occur for patient safety. This book will combine basic science principles, build on existing guidelines, and provide crucial tips on how to safely manage acute and chronic medical conditions in pregnancy. It is THE book for sub-specialists in Obstetric Medicine.