This book highlights both conventional and nanomaterials-based biosensors for the detection of cervical cancers. It describes developments in the selective and sensitive electrochemical biosensors based on DNA for the early diagnosis of cervical cancer. Further, this book covers other nano-biosensing systems such as nano-thermometry-based sensing platforms, mechanical sensing platforms encompassing piezoelectric-based sensors, electrochemical impedance spectroscopy based on PEGylated arginine functionalized magnetic nanoparticles, and field-effect transistor-based platforms for the early detection of cervical cancer. Also, it presents conventional platforms such as vibrational spectroscopy and polymerase chain reaction techniques for the diagnosis of cervical cancer. Finally, it reviews currently available biomarkers for the early diagnosis of cervical cancer and presents strategies for developing novel biomarkers based on cellular and molecular approaches. As such, this book is a comprehensive resource for researchers and clinicians working in cervical cancer diagnostics.

The present book on Molecular & Diagnostic Imaging and Treatment Strategies of ovarian cancer is one of two companion books with the second one being focused on Cell and Molecular Biology of Ovarian Cancer. Both books include new exciting aspects of ovarian cancer research with chapters written by experts in their respective fields who contributed their unique expertise in specific ovarian cancer research areas and include cell and molecular details that are important for the specific subtopics. Comprehensive and concise reviews are included of key topics in the field.

Stillbirth remains a sufficiently frequent outcome of pregnancy to pose great problems for clinicians, who have to treat extremely distressed patients. This concise but comprehensive book from an international team of contributors sets out clear guidelines for clinical procedures and patient management for the obstetrician, as well as the gynecologist and the gynecologic pathologist.

When mothers feel depressed in the months after childbirth, their feelings have often been dismissed as understandable reactions to the stress of caring for a new baby, perhaps complicated by family and marital demands. Most mothers cope, with varying degrees of support and success, but for many the neglect and misunderstanding of postnatal emotional problems can lead to long-term difficulties, with implications for their families as well as for mental health services. This book provides an understanding of depression following childbirth which draws together current theories and a synthesis of key research with a framework for intervention. It provides a novel way of thinking about postnatal depression, and a treatment program which is based on this model. The clinical programs and interventions which are outlined have been found to be effective at reducing postnatal depression. These programs are aimed at developing coping skills in women which:

• Reduce the symptoms of postnatal depression
• Improve maternal functioning in terms of self-esteem, assertiveness and coping
• Address marital and partner difficulties which often arise
• Deal with parent-infant difficulties the may exist
• Facilitate the use and development of existing social networks

The authors have reviewed current knowledge on postnatal depression, and given guidelines for best practice in a variety of approaches to treatment and prevention, Included is a detailed account of a tried-and-tested 10-week treatment program, together with materials and resources that a busy clinician might need to implement a similar program. Treating postnatal Depression will be a valuable resource for clinical psychologists, counsellors, psychiatrists, nurses, health visitors, midwives and other professionals who need to understand and deal with the emotional problems of mothers and babies. "A very readable book which presents an excellent overview of this important topic, and allows the authors to share their wealth of clinical experience in the clinical management of depressed mothers." Professor Peter Lewinsohn, University of Oregon "This book is a very timely and accessible approach for health care workers who treat women with postnatal depression Medical interventions alone are rarely adequate in the management of this disorder, an understanding of the psychological issues is essential, and this comprehensive manual, which deals with how to approach the complexities of the disorder, will aid workers significantly and, ultimately, benefit those who are suffering." Professor Anne Buist, University of Melbourne Austin & Repatriation Medical Centre

'Regardless of your level of obstetrics and gynaecology knowledge and experience, this book will most definitely have something to offer you.'- Tiago Villanueva in his Foreword. Undergraduate medical students often struggle with at least some of the specialty elements of their studies. Some face a further challenge with the advent of the Medical Schools Council Assessment Alliance (MSC-AA, formerly known as UMAP), with a move away from testing specific clinical facts to an assessment focused on preparing to be a foundation doctor and the knowledge such a trainee needs on a daily basis. Neel Sharma has written three self-assessment books - on psychiatry, obstetrics and gynaecology, and paediatrics - designed to help students tackle both the new form of assessment as well as the traditional style of examination. Questions covering all common presentations are included in SBA and EMQ formats with relevant, concise explanations as answers.

Pschyrembel Gynecology and Obstetrics is a reliable and comprehensive reference for gynecologists and obstetricians as well as physicians from other fields who require reference assistance. The book covers all areas of gynecology and obstetrics. The authors have thoroughly revised and updated this edition to ensure it meets the high quality standards of the Pschyrembel dictionary series.

My initial purpose in writing this book was to offer readers an update of my book Fetal Alcohol Syndrome and Fetal Alcohol Effects (Plenum, 1984), which con tained a broad overview of the history (actually the absence of any history) ofthe awareness of alcohol's teratogenic potential; a review of alcohol's pharmacology, especially with respect to pregnancy; a survey of the physical and behavioral effects of prenatal alcohol exposure; and an overview of the mechanisms sus pected of being responsible for those effects. I have omitted most of the previously examined historical and pharmacologi cal information because not much of what was previously discussed needed revision. On the other hand, because much more has been learned about the consequences of prenatal alcohol exposure and its potential mechanisms of action, I have considerably expanded my discussion of these topics. In doing so, I have attempted to include as much new material as possible without (I hope) being overly pedantic and thereby losing the proverbial forest for the trees. No book is ever entirely neutral in the topics it discusses, the issues it raises, or in its conclusions. In sifting through hundreds and oftentimes thousands of articles, writers have to choose which facts to emphasize and which to ignore. Every idea cannot be chronicled and every article cannot (and should not) be cited. In going about the business of picking and choosing, however, a writer has an obligation to present the arguments for and against a particular conclusion."

The aim of the two-volume set of Placenta and Trophoblast: Methods and Protocols is to offer contemporary approaches for studying the biology of the placenta. The chapters contained herein also address critical features of the female organ within which the embryo is housed, the uterus, and some aspects of the embryo-fetus itself, particularly those of common experimental animal models. In keeping with the organization used effectively in other volumes in this series, each chapter has a brief introduction followed by a list of required items, protocols, and notes designed to help the reader perform the expe- ments without difficulty. In both volumes, sources of supplies are given and illustrations highlight particular techniques as well as expected outcomes. A key aspect of these volumes is that the contributors are at the forefronts of their disciplines, thus ensuring the accuracy and usefulness of the chapters. Placenta research has progressed rapidly over the past several decades by taking advantage of the technical advances made in other fields. For example, the reader will note that many techniques, such as reverse transcriptase po- merase chain reaction, northern and western blotting, microarray analyses and in situ hybridization experiments, are routinely used for dissecting a wide range of experimental questions. Protein analysis and functional experiments on tissues and cells that comprise the maternal-fetal interface benefit from studies in en- crinology, immunology, and developmental biology. These volumes also present new ideas on investigating gene imprinting and gene transfer via viral vectors.

"Modern Management of Abnormal Uterine Bleeding "focuses on helping gynecologists refine their operative techniques and consider new approaches to the diagnosis, and treatment, of this highly challenging condition by investigating:

current scientific and clinical trails

varying menstruation conditions

less evasive management options versus surgical options

definitive surgical corrections

new forms of conservative therapy

Written by an internationally recognized team of experts and filled with scientific diagrams, photos, and illustrations, this cutting-edge new text covers the full range of surgical and medical treatments for menorrhagia, including the full rage of ablation corrections in an easy to read step-by-step format.

The first IVF conceived birth in 1978 resulted in a significant growth of third party reproductive options which continue to raise ethical, legal, and psychological questions. Third party reproduction procedures can involve as many as five people: sperm donor, egg donor, gestational carrier, and intended parents. "Third-Party Reproduction: A Comprehensive Guide" utilizes experts in the field to address the medical, psychological, ethical and legal aspects of sperm donation, egg donation, embryo donation, and the use of gestational carriers. In addition, there are chapters on the medical and ethical aspects of posthumous reproduction, religious aspects of third party reproduction, and how to avoid pitfalls of third party reproduction. Aimed at physicians, trainees, psychologists, nurses, and social workers whose practices may include patients considering third party reproduction, the intent of this book is to provide a comprehensive and practical overview of the many aspects of third party reproduction to help all those involved to better understand them. Patients considering third party reproduction may also find value in this book.

This beautifully illustrated book provides a practical step-by-step guide to all the laparoscopic and hysteroscopic procedures performed by gynecologists. Each procedure is described in detail and fully illustrated with color photographs. The potential complications are described, and the circumstances in which a procedure is contraindicated are examined. The Third Edition of the "Manual of Laparoscopic and Hysteroscopic Techniques" has been expanded and extensively updated with new chapters including: transvaginal hydrolaparoscopy, laparoscopy radical trachelectomy, laparoscopic abdominal cerclage, and hysteroscopy sterilization.
"Manual of Laparoscopic and Hysteroscopic Techniques" is an invaluable resource for busy practicing gynecologists who want to learn step-by-step techniques of a surgical procedure.

Expanded and updated, the new edition of the bestselling Clinical Protocols in Obstetrics and Gynecology is the definitive quick-reference for use in office practice and hospital settings. With information drawn from ACOG technical bulletins, OB/GYN publications, articles, textbooks, computer sources, and the author's vast personal experience, outlines of more than 400 clinical protocols help ensure that everyone on the team is on the same page. Flowcharts and algorithms make common problems seem simpler. Tables and decision trees make the information easy to refer to when running from room to room during a busy day in the office or hospital. This complete, up-to-date coverage makes Clinical Protocols in Obstetrics and Gynecology, Third Edition the best available study guide for board certification and a complete reference for busy obstetricians and gynecologists.

Endometriosis affects women in the reproductive years, is associated with pelvic pain and infertility, and - although not life threatening - can seriously impair health, with huge economic and social consequences. It is arguably the most frequent problem encountered in contemporary More...gynecology and is the subject of much ongoing research and innovation in management. This beautifully and comprehensively illustrated Atlas, now in its third edition, provides a useful educational tool for trainees and general obstetricians and gynecologists who may not be up-to-date with the most important recent research on the diagnosis and management of the condition; particularly expanded for this edition are the chapters on ultrasound imaging and the nutritional aspects of the subject.

Prognostic and Predictive Factors in Gynecologic Oncology takes a fresh look at a critical aspect of cancer treatment planning. An international team of authors reviews the traditional prognostic and predictive factors such as tumor grade, histologic subtype, and grade and then goes a step further to review the growing number of molecular discoveries that have increasing clinical significance. The book is organized into comprehensive sections on ovarian, endometrial and cervical cancer and includes up to date reviews, newly discovered molecular pathways, genetic markers, molecular imaging techniques, and their relevance to clinical medicine.

Prognostic and Predictive Factors in Gynecologic Oncology is illustrated with over 100 figures and is essential reading for oncologists, translational and basic scientists, as well as fellows, residents and students with a special interest in gynecologic oncology.

The Gynaeciorum libri, the 'Books on [the diseases of] women,' a compendium of ancient and contemporary texts on gynaecology, is the inspiration for this intensive exploration of the origins of a subfield of medicine. This collection was first published in 1566, with a second edition in 1586/8 and a third, running to 1097 folio pages, in 1597. While examining the origins of the compendium, Helen King here concentrates on its reception, looking at a range of different uses of the book in the history of medicine from the sixteenth to the nineteenth century. Looking at the competition and collaboration among different groups of men involved in childbirth, and between men and women, she demonstrates that arguments about history were as important as arguments about the merits of different designs of forceps. She focuses on the eighteenth century, when the 'man-midwife' William Smellie found his competence to practise challenged on the grounds of his allegedly inadequate grasp of the history of medicine. In his lectures, Smellie remade the 'father of medicine', Hippocrates, as the 'father of midwifery'. The close study of these texts results in a fresh perspective on Thomas Laqueur's model of the defeat of the one-sex body in the eighteenth century, and on the origins of gynaecology more generally. King argues that there were three occasions in the history of western medicine on which it was claimed that women's difference from men was so extensive that they required a separate branch of medicine: the fifth century BC, and the sixteenth and nineteenth centuries. By looking at all three occasions together, and by tracing the links not only between ancient Greek ideas and their Renaissance rediscovery, but also between the Renaissance compendium and its later owners, King analyzes how the claim of female 'difference' was shaped by specific social and cultural conditions. Midwifery, Obstetrics and the Rise of Gynaecology makes a genuine contribution not only to the history of medicine and its subfield of gynaecology, but also to gender and cultural studies.

Following on from the success of their previous standard textbook on Multiple Pregnancy, the authors have refocused their attention on prenatal assessment in multiple pregnancy and come up with condensed and revised material in a free-standing text. Multiple pregnancies are associated with higher levels of morbidity and fetal distress, and so effective and rapid diagnosis of problems is paramount. Those clinicians who would not have a practical application for all the aspects covered comprehensively in the earlier work will find this volume a clinically orientated and extremely useful addition to their working library.

This book presents and brings together research on child sexual abuse from various countries and cultures in the Arab Region. It addresses the multiple types of Child Sexual Abuse Exploitation and Trafficking (CSAET) and responds to the expanding burden of its diverse presentations. The book identifies appropriate structures for efficient programs that are to be accepted and developed by diverse cultures in the region, in order to develop an action plan to combat sexual violence against children. It studies the gathered to date child sexual abuse protection systems in the Arab region, covering issues such as children's rights, challenges of protection and advocates for peaceful, safe, healthy and happy environments for children and their families.

For over thirty years, the Oxford Handbook of Clinical Specialties has guided students and junior doctors through their clinical placements, renowned for providing all the information needed for both practice and revision in a deceptively small package. Now in its eleventh edition, the Handbook has been revitalized by an expanded team of specialty experts and junior doctors to guide readers through each of the specialties encountered through medical school and Foundation Programme rotations, while remaining true to the humanity and patient focus of the original edition. Updated with the latest advice and clinical guidelines, packed full of high-quality illustrations, boxes, tables, and classifications, and with a brand new chapter on how to survive your junior doctor years and beyond, this handbook is ideal for both study and use at direct point of care. Each chapter is clear and concise and filled with medical gems, with features including ribbons to mark your most-used pages and mnemonics to help you memorize and retain key facts. With reassuring and friendly advice throughout, this is the ultimate guide and revision tool for every medical student and junior doctor for each clinical specialty placement. This well-loved Handbook remains the perfect companion to the Oxford Handbook of Clinical Medicine, together encompassing the entire spectrum of clinical medicine and unmatched by any competitor in their class, helping you become the doctor you want to be.

For the ultrasound practitioner it is now more important than ever to have a rigorous understanding of fetal anatomy and development. This resource publishes a selection of very high-quality ultrasound images of the fetus alongside embryological preparations and fetoscopy images. This unique comparative technique will be an essential educational tool and work of reference for all involved in fetal ultrasound, including specialists in maternal-fetal medicine, ultrasound physicians, ultrasonography technicians, and midwives.

Key Features: 1. Provides inclusive and consolidated contents on disorders of female genital skin and mucosa. 2. Features high-quality illustrations and impressive treatment algorithms, making it a ready reckoner for dermatologists, gynaecologists, and general physicians. 3. Facilitates diagnosis and further management of vulvar disease in the skin of colour, thus optimizing patient care.

This title includes Foreword by David Taylor, Professor and Vice Dean of Leicester Medical School. Preparing for the Part 2 MRCOG examination remains a daunting and complex task, particularly as learning and revision often need to fit around clinical commitments. Much has been written about how to prepare for and pass exams, yet it remains surprising how often well-read candidates provide unsatisfactory answers in areas which they know well. Clearly, a sound understanding of the topic area is essential, but deeper knowledge also increases uncertainty, and the vast developments in the field mean that proficiency in all areas is next to impossible. Thus a critical point for postgraduate candidates, who more often than not will prepare for the examination in isolation, is to develop a real understanding of what the examination is meant to assess...This revision aid in obstetrics and gynaecology is based on the Extended Matching Question format (EMQ). It contains forty-two questions of varying degrees of difficulty, along with detailed answers. "MRCOG Part 2 Essential EMQs" is an indispensable study and revision aid for postgraduate medical students preparing for Part 2 of the Membership of the Royal College of Gynaecologists (MRCOG) examination or equivalent. "The number of published revision aids including this question format in postgraduate Obstetrics and Gynaecology remains limited. With this book we wanted to produce a comprehensive selection of EMQ, covering broad areas relevant to the speciality, which would be useful those preparing for postgraduate examinations at Part 2 MRCOG level or equivalent." - Marwan Habiba, Andrea Akkad, Justin Konje.

Preterm delivery is a major public health concern. Recent developments, such as the preventive use of progesterone, and new data on possible mechanisms of initiation of parturition, have placed the topic at the forefront of the interests and preoccupation of many in maternal-fetal medicine and obstetrics. This balanced, authoritative, and well-referenced work offers a rigorous underpinning of basic science, highlighted translational science sections, and evidence-based clinical guidelines.

This work includes Foreword by Phillip J S Steer, Professor of Obstetrics, Faculty of Medicine, Imperial College London. It includes Introduction by Gwyneth Lewis, National Clinical Lead for Maternal Health and Maternity Services, Department of Health, England and Director of the UK Confidential Enquiries into Maternal Deaths. 'The reductions in maternal mortality over the last half century are an eloquent testimony to the value of the technical expertise in life support that anaesthetists bring to the management of labour complications. Many direct causes of maternal death have been substantially reduced as a result of anaesthetic innovations ranging from advances in regional anaesthesia to the panoply of techniques used in intensive care. This book is essential reading.' - Phillip J Steer, in his Foreword. Offering a unique insight into real cases, this book covers the physiology, pharmacology and organisational factors involved in previous maternal deaths, highlighting key lessons to be learnt. This practical guide provides an ideal introduction for new anaesthetists and up-to-date information for senior practitioners, particularly those who cover labour wards. It is also invaluable for anaesthetic nurses, obstetricians and midwives. 'For more than 50 years the Confidential Enquiries into Maternal Deaths in the UK have collected together invaluable information about why mothers die in pregnancy and childbirth. For the first time ever, this unique book collects together all the valuable lessons into one volume. Experts in their fields provide a physiological, pharmacological, and evidence based commentary on the events of each death. The overall result pays homage to the value of collecting together lessons from the past, and we hope will help people avoid repetition of these situations in the future.' - Daryl Dob, Anita Holdcroft and Griselda Cooper, in the Preface.

Reproductive Endocrinology and Infertility provides an overview of the most frequently encountered clinical challenges faced by medical students and residents. Part I begins with chapters on reproductive hormonal physiology and development to provide a basis for understanding the management of the most common reproductive clinical problems that confront obstetrician-gynecologists and other practitioners in women's health. Several of the chapters, including obesity, premenstrual syndrome, menopause and imaging, provide a cross-disciplinary approach to endocrine related problems common among reproductive aged women. Part II includes chapters on the evaluation of infertility, as well as surgical and medical approaches to treating infertility in men and women. The chapter on alternative medicine provides a basis for understanding the increasingly popular use of therapies such as acupuncture and herbal treatments. The last chapter discusses the influence of environmental factors on fertility, an important field that is often ignored in the traditional approach to infertility. This text is meant to be used as a portable reference with readily accessible information including a summary of key points in each chapter. All of the contributors are involved in residency training programs and understand the kinds of patient management questions that are encountered in a busy practice. Our goal with this book is to provide information that will support solid patient management and hopefully pique the appetite to learn more.