A concise clinical reference that facilitates the diagnosis of intrauterine and perinatally acquired infections was the goal in creating the Congenital and Perinatal Infections: A Concise Guide to Diagnosis. Information about the natural history, m- agement, and outcome of these infections is well detailed in many other sources and so has not been included. Rather, the focus of the book is diagnosis. The initial chapters provide general information about serological and nonserological assays that are used for the diagnosis of infections, and a chapter about the placenta includes details about histopathological findings that can be helpful with the diagnosis of congenital inf- tions. The remainder of the book is devoted to the diagnosis of specific congenital and/ or perinatal infections. As illustrated in the chapters about specific infections, the approach to diagnosis of a congenital or perinatally acquired infection in the neonate begins, when possible, with consideration and diagnosis of infection in the pregnant woman, knowledge of how the infection is transmitted, and the risk of that infection for the woman and her fetus or neonate. The possibility of congenital or perinatal infection in neonates is usually considered because of the diagnosis of, or concern about a s- cific infection in, a mother during pregnancy that can be transmitted to the neonate or because of clinical findings in the neonate at birth that suggest an infectious cause.

Endometrial cancer remains the most frequent gynaecological cancer in first world countries.This bench book on endometrial pathology distils the current literature to provide a practical text on endometrial pathology. Differential diagnosis is emphasised, and the clinical correlates of pathology are also stressed to make this a clinically useful book.Fully updated and including over 400 colour images, this book provides a valuable resource for the practising pathologist in general and community hospitals as well as in teaching hospitals.

The best selling resource for the OB/GYN clerkship Excel on your rotation, impress on the wards, and score your highest on the shelf exams with this best-selling reference. This new edition of First Aid for the OB/GYN Clerkship has been updated with the latest clinical perspectives and research. Ask just about any student who has been through their OB/GYN rotation and they will tell you that THIS was the resource they turned to. It not only aligns with national clerkship curricula, but also follows the shelf exam blueprint and is full of helpful mnemonics, ward tips, exam tips, and integrated mini-cases. The text highlights all of the important topics, presenting a clear, concise review based on the clerkship's core competencies. Thoroughly revised, this new edition will help you prepare for the clerkship and also guide you in the clinical diagnosis and treatment of the many conditions you will see during your rotation. First Aid for the OB/GYN Clerkship features: The latest clinical research and perspectives Helpful mnemonics Ward tips and integrated mini-cases Images, diagrams, and flow charts in a fresh new-full color design Summary boxes with high-yield information needed for exam success

Medical imaging has been transformed over the past 30 years by the advent of computerized tomography (CT), magnetic resonance imaging (MRI), and various advances in x-ray and ultrasonic techniques. An enabling force behind this progress has been the (so far) exponentially increasing power of computers, which has made it practical to explore fundamentally new approaches. In particular, what our group terms "model-based" modalities-which produce tissue property images from data using nonlinear, iterative numerical modeling techniques-have become increasingly feasible.

Alternative Breast Imaging: Four Model-Based Approaches explores our research on four such modalities, particularly with regard to imaging of the breast: (1) MR elastography (MRE), (2) electrical impedance spectroscopy (EIS), (3) microwave imaging spectroscopy (MIS), and (4) near infrared spectroscopic imaging (NIS). Chapter 1 introduces the present state of breast imaging and discusses how our alternative modalities can contribute to the field. Chapter 2 looks at the computational common ground shared by all four modalities. Chapters 2 through 10 are devoted to the four modalities, with each modality being discussed first in a theory chapter and then in an implementation-and-results chapter. The eleventh and final chapter discusses statistical methods for image analysis in the context of these four alternative imaging modalities.

Imaging for the detection of breast cancer is a particularly interesting and relevant application of the four imaging modalities discussed in this book. Breast cancer is an extremely common health problem for women; the National Cancer Institute estimates that one in eight US women will develop breast cancer at least once in her lifetime. Yet the efficacy of the standard (and notoriously uncomfortable) early-detection test, the x-ray mammogram, has been disputed of late, especially for younger women. Conditions are thus ripe for the development of affordable techniques that replace or complement mammography. The breast is both anatomically accessible and small enough that the computing power required to model it, is affordable.

"Dangerous Motherhood" is the first study of the close and complex relationship between mental disorder and childbirth. Exploring the relationship between women, their families and their doctors reveals how explanations for the onset of puerperal insanity were drawn from a broad set of moral, social and environmental frameworks, rather than being bound to ideas that women as a whole were likely to be vulnerable to mental illness. The horror of this devastating disorder which upturned the household and turned gentle mothers into disruptive and dangerous, mad women, was magnified by its occurrence at a time when it was anticipated that women would be most happy in the fulfillment of their role as mothers.

Practicing specialists in pathology, laboratory medicine, and obstetrics comprehensively summarize the latest scientific findings and their experiences in the use and interpretation of laboratory testing in patients who are pregnant or experiencing recurrent pregnancy loss. Topics of interest include the effects of normal physiological changes on test results, test selection for diagnosis, changes in reference ranges, monitoring the pregnant patient, new technologies, and the limitations of laboratory testing. The authors not only clearly explain currently used test methods and technologies for the nontechnical reader, but also provide comprehensive details for laboratory professionals. The comprehensive appendix that compiles published normal reference ranges by first, second, and third trimester consttitutes an excellent resource for professionals caring for pregnant women.

This book is an accessible guide to caring for survivors of sexual and gender-based violence (SGBV). Sexual violence is broadly defined in order to include sexual assault, but also often forgotten subjects such as female genital cutting, sex trafficking, and military sexual violence. The average practitioner, gynecologist or otherwise, will undoubtedly encounter a victim of some sexual violence during their time in practice and this guide is designed to answer all questions on how to approach, treat, and understand a survivor of sexual violence. Written by a multidisciplinary team of medical, psychological, and legal experts, the book is organized into four sections. The first section begins with a scholarly analysis of trauma and how to discuss that trauma with patients. The second section covers types of violence and populations at risk, including intimate partner violence, sex trafficking, and LGBTQ considerations. The third section provides critical focus on the examination procedure, providing strategies for speaking to survivors and conducting a sensitive medical examination. Within each of these chapters, the reader will find experts sharing their tips, best practices, and understandings of exactly how trauma affects care. The final section covers medicolegal legal issues, providing a basic introduction to general legal processes regarding sexual violence matters in the US in order to serve as a resource for any practitioner presented with legal questions by a patient. This book gives a comprehensive overview of clinical care for survivors of SGBV. The clinical focus of this book goes beyond emergency room and crisis intervention protocol described in other books and makes it an ideal guide for all general health practitioners treating this population.

As research in neuroscience increasingly points to the unparalleled influence of the first 1000 days of life from conception to two years of age in determining the baby's life trajectory, the need for high-quality early parenting education delivered by knowledgeable and dedicated professionals becomes ever more apparent. This book describes the global aims of early parenting education. It identifies the key areas that research suggests are important: building a relationship with the unborn and newborn baby; preparing for labour and birth; supporting parents' mental health; protecting the couple relationship across the transition to parenthood; and education for special groups such as same-sex couples, women with fear of birth, prisoners, military wives and parents from black and minority ethnic backgrounds. All practitioners providing early parenting programmes - midwives, health visitors, family link workers, children's centre staff and voluntary sector teachers - will gain new ideas for their practice in this book. Students taking midwifery and early childhood courses will find much to support their studies. Ultimately, the book provides inspiration for all those who are committed to the role of parenting education in reducing social inequalities.

Chronic pelvic pain is a common debilitating condition that impairs quality of life and reproductive function in the female population worldwide. It is also an area in which the level of knowledge is generally poor among gynecologists. This book will help gynecologists and pain management specialists optimize assessment and treatment of women with chronic pelvic pain. It addresses the most common conditions causing chronic pelvic pain in women and offers practical guidelines for treatment. Exploring issues such as pudendal neuralgia and pain caused by pelvic nerve injuries and pelvic mesh. Other sections are dedicated to examining the psychological impact of pelvic pain and the impact of pain on sexuality and relationships. Algorithms on how to work-up and treat patients with chronic pelvic pain are a valuable addition, as well as advice on what to do in situations where known treatments have failed.

The National Institute of Health interrupted their huge HRT study in July 2002 when they found that the drug Prempro, a combination of estrogen and progestin, had detrimental health effects. The women who took the drug exhibited an increased risk for breast cancer, heart disease, and stroke.
Women can lose up to 20% of their bone mass in the first seven years after menopause. Post-menopausal women are twice as likely as men to die of a heart attack. Natural estrogen is the answer.
In this book the authors provide a healthy and natural alternative to HRT. They not only provide nutritious, healthy and delicious recipes; they also explain why phytoestrogens -- plant estrogens -- can alleviate the symptoms of menopause and promote a woman's health. THE NATURAL ESTROGEN DIET AND RECIPE BOOK is the answer to women who are seeking to retain their health through and after menopause in a completely safe, effective and natural way. It also shows women of any age how to make healthy food a permanent part of their lives.

A discussion of all the key issues in the use of human pluripotent stem cells for treating degenerative diseases or for replacing tissues lost from trauma. On the practical side, the topics range from the problems of deriving human embryonic stem cells and driving their differentiation along specific lineages, regulating their development into mature cells, and bringing stem cell therapy to clinical trials. Regulatory issues are addressed in discussions of the ethical debate surrounding the derivation of human embryonic stem cells and the current policies governing their use in the United States and abroad, including the rules and conditions regulating federal funding and questions of intellectual property.

Cervical laminoplasty for the treatment of ossification of the posterior longitudinal ligament was developed and refined in Japan during the 1970s. Since that time, various cervical laminoplasty techniques have been further analyzed and modified, and have proven to be clinically successful. Until now cervical laminoplasty has been practiced primarily in Japan, and surgeons outside Japan had only limited access to the detailed English literature needed to make full use of the procedures. This book fills that gap in English information and provides a detailed, up-to-date guide to performing safe and effective cervical laminoplasty. Drawing on the latest knowledge from Japan, the book covers the history of cervical laminoplasty, surgical anatomy, basic procedures, modified procedures, possible complications, and perspectives on the future of expansive laminoplasty. This volume by leaders in the field is an excellent guide for all surgeons interested in laminoplasty.

This immensely practical handbook provides the busy clinician with a self-contained account of the diagnosis and management of ectopic pregnancy. Such pregnancies, which develop outside the uterine cavity, are an increasingly common occurrence. The focus throughout is on diagnosis and management issues, and the author provides rapid solutions to the most difficult problems posed by ectopic pregnancy. The text is fully supported by numerous and helpful ultrasound images, line diagrams illustrating surgical techniques, and by highlighted summaries of key facts and decision trees.

Ultrasound and Endoscopic Surgery in Obstetrics and Gynaecology focuses and highlights the pivotal role these two techniques play in modern obstetrics and gynaecology. Taking a problem-orientated approach, the book includes sections on menorrhagia, postmenopausal bleeding, endometrial malignancy, urogynaecology, ovarian masses, endometriosis, early pregnancy complications and infertility. A multi-contributed book with short, practical chapters, the book is well illustrated with more than 60 colour illustrations. Ultrasound and Endoscopic Surgery in Obstetrics and Gynaecology uniquely combines these two fields to demonstrate management of common gynaecological conditions based on accurate ultrasound diagnosis and minimal access treatment. An authoritative practical 'how-to' guide, this book will be invaluable for practitioners to learn and perfect both techniques and use them to their maximum potential.

Within 10 chapters this book addresses the whole gamut of questions that may arise in the context of pregnancy resulting from assisted reproduction. Incidence of abortion, extrauterine pregnancy or chromosomal abnormalities, pregnancy complications, problems regarding mode of delivery and the health status of children at birth are covered as well as the further development of the children and the social structure of the families. Topics such as follow-up of families in lesbian relationships and following gamete donations are also discussed.

Experimental and clinical researchers from a wide range of disciplines present a wealth of fresh scientific information on the biochemistry, molecular biology, pharmacology, and clinical activity of SERMs. The basic science chapters of the book focus-with an eye to the development of the ideal SERM-on the complex mechanisms of estrogen action, including ligand-dependent conformational changes in alpha and beta, and the recruitment of co-activators and co-repressors which modulate the estrogen receptor transcriptional activity and contribute to its crosstalk with growth factor signaling. The clinical presentation reviews the data accumulated on currently available SERMs, primarily tamoxifen and raloxifene, in cancer treatment and prevention, as well as their effects on the reproductive, vascular, skeletal, and central nervous systems. A tentative approach to menopause-related health issues is also provided for women with and without a previous diagnosis of localized breast cancer.

Updated, revised, and reorganized, the Second Editions in the Clinical Sciences reflect the format of the USMLE Step 2. Each volume systematically presents the core information of a single segment of the medical curriculum, from Family Medicine to Psychiatry. You will also learn time-honored tricks of the trade, as well as the latest advances in clinical medicine: new diagnostic tools, new therapeutic interventions, and new pharmacologic options.

Epigenetics is the study of how certain genes are activated without modification at the DNA sequence level, resulting in genetically similar individuals having different clinical outcomes. As contemporary medicine increasingly aims to personalize the medical approach to a patient's genetic profile, the factors that can affect which genes are expressed also increase in importance and relevance to the clinician. This text from experts will give the clinician in Reproductive Medicine a reliable grounding in current thinking and research on this fast-moving topic, with many clinical implications.

The female patient with chronic kidney disease often requires care that differs from the male patient. Particularly in the pregnant patient, a specialized body of knowledge is required to provide optimal care. This book focuses on such issues encountered during pregnancy including physiology and pathophysiology of pregnancy, hypertension, preeclampsia, various electrolyte disorders, nephrolithiasis, pharmacological management in the pregnant patient with kidney disease and during breastfeeding, acute kidney and chronic kidney disease, dialysis of the pregnant patient, lupus nephritis, thrombotic microangiopathy, glomerular disease management, use of renal biopsy during pregnancy, care of the female transplant patient, contraceptive counseling and postpartum care, various endocrine disorders, and bone disease in the female patient with chronic kidney disease. This book features the latest evidence and clinical approaches for the beginner or for the experienced practitioners who care for pregnant woman or even for those who require expertise in women's health. Written by experts in the field, Obstetric and Gynecologic Nephrology: Women's Health Issues in the Patient with Kidney Disease is a valuable resource for clinicians and practitioners involved in the care and treatment of obstetric and gynecologic patients afflicted with kidney disease.

Is women's destiny rooted in their biology? Since the end of the eighteenth century the science of gynecology has legitimized the view that women are "naturally" fitted for activities in the private sphere of the family. This book argues that the definition of femininity as propounded by gynecological science is a cultural product of a wider, more political context. Providing a unique account of gynecology in practice, it shifts the historical focus from the use to the production of ideas about "women's nature." Dr. Moscucci traces the origins of gynecology to the emergence of a predictable "science of man" in the late eighteenth century and charts the ideological, professional and institutional development of the subject up to the foundation of the Royal College of Obstetricians and Gynaecologists in 1929. Case-studies of Victorian gynecological practice at two London hospitals illustrate the changing pattern of institutional gynecology, affording valuable insight into the relationship between gynecologists and patients. The book also stresses the equal importance of class and gender ideology in shaping medical views about women's diseases and their treatment.

Cancer and Pregnancy covers the clinical challenges to diagnosing and treating malignancies in the pregnant patient; however, the book also shows how an understanding of the common features of both processes (rapid cell proliferation) may lead to novel anti-cancer treatment options. The book should be read by obstetricians and gynaecologists, clinical oncologists, reproduction specialists, and those involved in investigation of development, biology, toxicology, immunology, as well as cancer research.

With mesh surgery for prolapse sometimes proving problematic, there has been a resurgence of professional medical interest in more traditional methods for the management of prolapse and of stress urinary incontinence. This concise guide to the practical aspects of pessary use will be of interest to all gynecologists involved in the clinical management of the patient with these problems. Contents: Historical review * Pessaries for pelvic organ prolapse * Incontinence pessaries * Pessary fitting * Pessary care * Outcomes of pessary use * Current clinical studies on vaginal pessaries Cover image of vaginal pessaries (c) 2019 Rick Hicaro, Jr., Chicago, IL 60647, USA

The alternation between urine retention and discharge several times daily from a nappy to the cessation ofall vital functions only becomes the subject baby's first wet of greater attention if the harmony of the structure and function of the bladder is disturbed. Functional disturbances of the lower urinary tract are not only of great socio-economic importance, but are also a considerable personal burden for the patient. Hence urinary incontinence is rightly classified as a severelydisabling illness (Hauri 1985). Opinions still differ regarding the morphological basis ofurinary continence.The Terminologia Anatomica (1998) defines a musculus sphincter urethrae internus (in- ternal urethral sphincter) and a musculus sphincter urethrae externus (external ure- thral sphincter),which in the older nomenclature were known as musculus sphincter vesicae and musculussphincterurethrae,respectively.The internal urethral sphincter isascribed apurelyinvoluntaryandthe externalurethralsphincterapurelyvoluntary innervation. The significance of the musculature of the pelvic floor for maintaining urinarycontinence has notyetbeen ascertained. Duringnumerous urologicaloperations (forinstancetransurethralresectionofthe prostate and bladder neck incisions), the only involuntarily innervated sphincter at the collum vesicae,the internalurethralsphincter,is partiallyorcompletelydestroyed (Fig. 27C,D).All the patients remain continent as long as the externalurethral sphinc- ter remains intact.Howcan apurelyvoluntarilyinnervated sphincterlikethe external urethral sphincter ensureconstant continence in such cases? Improving the continence rate after radical surgery is a key topic of urological research. The incontinence rate after radical prostatectomy is still between 8.1% (third-degree incontinence) and41.4% (first- to second-degree incontinence; Rudyet al. 1984; Igel et a1.1987; Schroderand Ouden 1992).