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Prostaglandins and their Inhibitors in Clinical Obstetrics and Gynaecology (Paperback, Softcover reprint of the original 1st ed. 1986)
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Prostaglandins and their Inhibitors in Clinical Obstetrics and Gynaecology (Paperback, Softcover reprint of the original 1st ed. 1986)
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It is clear today that several prostaglandins play an important
role in the regulation of many of the physiological events of the
reproductive organs in the human. Both naturally occurring
prostaglandins and their analogues are used routinely in many
countries to ripen the cervix and induce labour at term as well as
to dilate the cervix and to terminate pregnancy. Prostaglandin
biosynthesis inhibitors are widely used in the treatment of primary
dysmenorrhoea. The editors have aimed at an accurate, thorough, yet
easily under standable review of the status in 1986 of medical
knowledge regarding both the physiological importance and the
clinical use of prostaglan dins and their inhibitors in obstetrics
and gynaecology. I believe this book will be of value for all
clinicians concerned with reproductive health. The list of authors
guarantees an authoritative and up-to-date review of this active
field. SUNE BERGSTROM Karolinska Institutet, Stockholm, Sweden
Table Examples of clinical use of natural prostaglandins and some
prostaglandin analogues Indications Prostaglandin Route of
administration Manufacturer Dilatation of the cervix prior
15-methyl-PGF * Intramuscular Upjohn, USA 2 to vacuum aspiration
16-phenoxy-PGE methyl sulphonylamide Intramuscular Schering AG,
West Germany 2 16,16-dimethyl-PGE methyl ester 1 Vaginal ONO,
Japan; May & Baker, UK Second trimester abortion Intra
-amniotic Upjohn, USA; ONO, Japan PGF 20 Upjohn, USA PGE Vaginal 2
Upjohn, USA 15-methyl-PGF 2.
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