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Implantation - Biological and Clinical Aspects (Paperback, Softcover reprint of the original 1st ed. 1988)
Loot Price: R2,865
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Implantation - Biological and Clinical Aspects (Paperback, Softcover reprint of the original 1st ed. 1988)
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The advent of assisted conception procedures such as in-vitro
fertili sation (IVF) has provided the impetus for exploration of
the factors that lead to the establishment of pregnancy. This
collection of papers from leading research workers brings together
current concepts of the processes which may be of importance in
implantation. The complex signals from the embryo to the ovary,
endometrium and myometrium are now being revealed through studies
in both primates and other mammalian species. This book addresses
the interrelationship of pituitary and ovarian hormones in
controlling ovulation and the preparation of the intrauterine
environment for implantation. Once fertilisation has occurred and
trophoblast has formed, the next vital step is the production of
materials which signal the presence of the pregnancy to the rest of
the body. Trophoblastic proteins and other early-pregnancy factors
are prime candidates for this role. Recent studies have emphasised
the importance of the intrauterine environment in implantation.
Specific secretory products of the endometrium have great potential
in this process. The prostaglandins also play an essential part.
Immunological adjustments are now considered a condition for the
successful establishment of pregnancy. The possible use of immuno
therapy in the treatment of recurrent abortion has highlighted
interest in this area. The use of immunological techniques for
contraception are in their infancy but offer much hope for the
future.
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