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Urinary Cytology - Phase Contrast Microscopy and Analysis of Stained Smears (Paperback, Softcover reprint of the original 1st ed. 1977)
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Urinary Cytology - Phase Contrast Microscopy and Analysis of Stained Smears (Paperback, Softcover reprint of the original 1st ed. 1977)
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Cytologic diagnosis of cancer has its roots in clinical micro scopy
as it was shaped during the first half of the 19th century. In
reviewing some of the early writing on this subject, one is amazed
at the accuracy of the descriptions and soundness of the
observations. Cytology of the urine is no exception: in 1864
Sanders described fragments of cancerous tissue in the urine of a
patient with bladder cancer (Edinburgh Med. J. 111, 273). This
observation was confirmed by Dickinson in 1869 (Tr. Path. Soc.
London, 20, 233). It is a source of special pride to me that in
1892 a New York pathologist, Frank Ferguson, advocated the
examination of the urinary sediment as a best means of diagnosing
bladder cancer, short of cystoscopy. Papanico laou freely
acknowledged these contributions while estab lishing sound
scientific bases for continuation and spread of this work.
Papanicolaou's work in the area of the urinary tract has not fallen
on dead ears. He documented to several urologists who were within
his sphere of personal influence, mainly Dr. Victor Marshall,
Professor of Urology at Cor nell University Medical School, that
urinary tract cytology was a reliable tool in the diagnosis of
urothelial carcinoma. Some of us who have attempted to spread the
master's word had their share of success within institutions with
which we were associated.
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