Traces the history of the study of tumor viruses and its role in driving breakthroughs in cancer research. Worldwide, approximately one-fifth of human cancers are caused by tumor viruses, with hepatitis B virus and HPV being the leading culprits. While the explosive growth in molecular biology in the late twentieth century is well known, the role that the study of tumor viruses has played in driving many of the greatest breakthroughs is not. Without the insights gained by studying tumor viruses, many significant theoretical advancements over the last four decades in cellular and molecular biology would not have been made. More practically, the study of tumor viruses has saved thousands, if not millions, of lives. In Cancer Virus Hunters, Gregory J. Morgan traces the high points in the development of tumor virology, from Peyton Rous's pioneering work on chicken tumors in 1909 to the successful development of an HPV vaccine for cervical cancer in 2006. Morgan offers a novel approach to understanding the interconnectedness of a long series of biomedical breakthroughs, including those that led to seven Nobel prizes. Among other advances, Morgan describes and contextualizes the science that prompted the discoveries of reverse transcriptase, RNA splicing, the tumor suppressor p53, the vaccine for hepatitis B, and the HIV test. He also explores how "cancer virus hunters" have demonstrated the virtue of beginning with a simple system, even when investigating a complex disease like cancer. Based on extensive archival research and over fifty interviews with experts, Cancer Virus Hunters is a tour de force summarizing a century of research to show how discoveries made with tumor viruses came to dominate the contemporary understanding of cancer. By showcasing the scientists themselves, the book makes for an unusually accessible journey through the history of science. It will be of interest to biomedical professionals-especially in oncology, hepatology, and infectious disease-in addition to historians of science and anyone interested in cancer research.

Margarita Diaz-Andreu offers an innovative history of archaeology during the nineteenth century, encompassing all its fields from the origins of humanity to the medieval period, and all areas of the world. The development of archaeology is placed within the framework of contemporary political events, with a particular focus upon the ideologies of nationalism and imperialism. Diaz-Andreu examines a wide range of issues, including the creation of institutions, the conversion of the study of antiquities into a profession, public memory, changes in archaeological thought and practice, and the effect on archaeology of racism, religion, the belief in progress, hegemony, and resistance.

This book examines the persona of the "man of science" in the Victorian period as it was shaped by Thomas Huxley, the leading British naturalist and notorious popularizer of Darwinian theory. It demonstrates how the scientific practitioner was regarded as a moral and religious figure; simultaneously considered to be the epitome of the secular, professional scientist. Breaking with traditional biographies, this fascinating portrait treats Huxley as the consummate British "man of science" and reflects on the historical significance of scientific authority.

This book presents a substantial collection of essays from a wide range of well respected scholars addressing several aspects of Piero Sraffa's economics in light of continuing controversies over the interpretation that should be placed on his work. It moves beyond extant scholarship with an added emphasis on the philosophical dimension of Sraffa's seminal work, Production of Commodities by Means of Commodities. Contributors probe new ways of thinking about the political economy of Sraffa and in doing so, alongside the comments to each contribution by other scholars, provide a cutting edge debate and discussion on non-mainstream economic theory. This book will be of interest to academics and advanced graduate students in economics, with additional interest from scholars in philosophy and the methodology of science.

This fascinating biographical dictionary surveys the American women who have made significant contributions to major fields of scientific endeavor since 1950. In American Women in Science, each of the concise A-Z biographies of more than 300 women includes information on the woman's background, employment history, honors, and publications, and then places her achievements in the appropriate scientific and social context. Other features include illustrations, bibliographic references, and an index that lists women by scientific discipline. Among the biographical entries are Jane Brody, Helen Mary Caldicott, Ada E. Deer, Jane Delgado, Dian Fossey, Margaret Hamilton, Devrie Intriligator, Shirley Ann Jackson, and Judith Kimble. All biographical entries are indexed by profession, name, and subject, making this an outstanding reference for students and teachers of women's studies and science as well as anyone interested in the scientific achievements of women. Biographical entries of female scientific figures from Jane Brody and Helen Mary Caldicott to Shirley Ann Jackson and Judith Kimble All entries are indexed by profession, name, and subject Bibliographic references and illustrations

This book analyzes the evolution of Italian viticulture and winemaking from the 1860s to the new Millennium. During this period the Italian wine sector experienced a profound modernization, renovating itself and adapting its products to international trends, progressively building the current excellent reputation of Italian wine in the world market. Using unpublished sources and a vast bibliography, authors highlight the main factors favoring this evolution: public institutional support to viticulture; the birth and the growth of Italian wine entrepreneurship; the improvement in quality of the winemaking processes; the increasing relevance of viticulture and winemaking in Italian agricultural production and export; and the emergence of wine as a cultural product.

In this volume Pierre Duhem first gives an overview of 19th century electricity and magnetism. Next, he applies his keen historical, philosophical, and physical intuition to critiquing Maxwell's theories, especially his electromagnetic theory of light and the ad hoc introduction of displacement current, which he considers too much a product of the "esprit de geometrie" than the "esprit de finesse," as Pascal calls it. In this book, Duhem is guided by the principle that a theory that offers contradictions, even if the theory is posed by a genius, needs to be analysed and discussed until a clear distinction can be made between the propositions likely to be logically demonstrated and statements that offend logic and which must be transformed or rejected. Furthermore, Duhem felt, in criticizing such a theory one must guard against narrowness of mind and petty corrections which would make one forget the merit of the inventor; and, more importantly, one must guard against the blind superstition which, for admiration of the author, would hide the serious defects of the work. He is not so great a genius that he surpasses the laws of reason. Pierre Duhem (1861-1916), chairman of theoretical physics at Bordeaux in 1984-1916, is well-known for his works in the history and philosophy of science.

This monograph is dedicated to the lives and scientific achievements of the physiology pioneers Warren and Margaret Lewis. Their story spans the first half of the 20th century, from their respective educations through early, independent research to joint research from 1910 to 1955. Among the numerous developments they initiated, were the discovery of pinocytosis, the beginnings of video microscopy and the development of the first mammalian tissue cultures. Their research expanded the theoretical knowledge of cell structure and function. On a more practical level, they advanced many laboratory methods, like the first recipes for culture media. The text is beautifully enriched with personal anecdotes about their lives. This is the story of two scientific pioneers in the context of early 20th century biology and physiology. It is an inspiration for senior and aspiring researchers.

"Egyptian Mummies" is regarded by egyptologists as the classic account of mummification in ancient Egypt. Originally published in 1924, its re-issue in complete form will be welcomed by all those who have sought rare second hand copies in vain. This book provides the most comprehensive account available of the technical processes and materials employed by the ancient Egyptian embalmers together with a historical analysis of their modification throughout the dynastic period. The authors draw on fully illustrated archaeological and pathological evidence together with Egyptian and Greek textual references to provide a thorough survey of the mummification process and attendant funeral ceremonies, and to offer clues to an understanding of the custom's significance and the reasons for its adoption.

Statisticians of the Centuries aims to demonstrate the achievements of statistics to a broad audience, and to commemorate the work of celebrated statisticians. This is done through short biographies that put the statistical work in its historical and sociological context, emphasizing contributions to science and society in the broadest terms rather than narrow technical achievement. The discipline is treated from its earliest times and only individuals born prior to the 20th Century are included. The volume arose through the initiative of the International Statistical Institute (ISI), the principal representative association for international statistics (founded in 1885). Extensive consultations within the statistical community, and with prominent members of ISI in particular, led to the names of the 104 individuals who are included in the volume. The biographies were contributed by 73 authors from across the world. The editors are the well-known statisticians Chris Heyde and Eugene Seneta. Chris Heyde is Professor of Statistics at both Columbia University in New York and the Australian National University in Canberra. He is also Director of the Center for Applied Probability at Columbia. He has twice served as Vice President of the ISI, and also as President of the ISI's Bernoulli Society. Eugene Seneta is Professor of Mathematical Statistics at the University of Sydney and a Member of the ISI. His historical writings focus on 19th Century France and the Russian Empire. He has taught courses on the history of probability-based statistics in U.S. universities. Both editors are Fellows of the Australian Academy of Science and have, at various times, been awarded the Pitman Medal of the Statistical Society of Australia for their distinguished research contributions.

In the year 1889 Sofya Vasilievna Kovalevskaya, Profes- sor of Mathematics at the University of Stockholm, pub- lished her recollections of growing up in mid-nineteenth century Russia. Professor Kovalevskaya was already an international celebrity, and partly for the wrong reasons: less as the distinguished mathematician she actually was than as a "mathematical lady"-a bizarre but fascinating phenomenon.* Her book was an immediate success. She had written it in Russian, but its first publication was a translation into Swedish, the language of her adopted homeland, where it appeared thinly disguised as a novel under the title From Russian Ltfe: the Rajevski Sisters (Sonja Kovalevsky. Ur ryska lifvet. Systrarna Rajevski. Heggstrom, 1889). In the following year the book came out in Russia in two *"My gifted Mathematical Assistant Mr. Hammond exclaimed ...'Why, this is the first handsome mathematical lady I have ever seen!'" Letter to S. V. Kovalevskaya from].]. Sylvester, Professor of Mathe- matics, New College, Oxford, Dec. 25, 1886.

In 1913, English physicist Henry Moseley established an elegant method for 'counting' the elements. Soon afterwards, it became clear that there were precisely seven elements missing from the periodic table-those that had yet to be isolated among the 92 naturally occurring elements from hydrogen (#1) to uranium (#92). In A Tale of Seven Elements, Eric Scerri will present the discovery of those seven elements, five of which are radioactive and three or possibly four of were first isolated by women. The book covers a period roughly spanning the two world wars, beginning with the discovery of protactinium in 1917 and ending with that of promethium in 1945. In some cases, the state of war directly influenced attempts to isolate some of the seven elements-this is true of protactinium, when, in 1916, its discoverer, Lise Meitner, wrote of the problems she encountered in purchasing even the most basic items of laboratory equipment. During the second war, the discovery of nuclear fission, also by Meitner and her associates, quickly led to the development of the nuclear weapons program and the associated technologies of particle accelerators. Clearly, scientific discoveries occur within a social and political context and the discovery of the seven elements is no exception. This book draws together for the first time the fascinating stories of the discoveries of these seven elements, placing them in historical context.

This volume explores the history of epidemiology from the mid-twentieth century to the present. Epidemiology has exerted major influence on the way that both infectious and chronic diseases are conceptualized and controlled, and, more generally, on the way that people in modern societies think about health, behavior, longevity, and risk. This collection consists of a series of in-depth analyses of the roots, development, and impact of epidemiological research, illuminating the complex relationship between medical research and data on the one hand, and social and cultural factors on the other. The thematical and geographical scope of the book ranges from indigenous and participant perspectives to the visualization of pandemics, and from Circumpolar North to East Africa. The book identifies significant historical changes and the driving forces behind them, charting forms of science-society interaction that characterize modern epidemiology. Chapter 1 and chapter 4 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

"A scientific opinion is one which there is some reason to believe is true; an unscientific opinion is one which is held for some reason other than its probable truth". One of Russell's most important books, this early classic on science illuminates his thinking on the promise and threat of scientific progress. Russell considers three questions fundamental to an understanding of science: the nature and scope of scientific knowledge, the increased power over nature that science affords, and the changes in the lives of human beings that result from new forms of science. With customary wit and clarity, Russell offers brilliant discussions of many major scientific figures, including Aristotle, Galileo, Newton and Darwin. Unavailable for many years, this book should prove interesting reading for Russell followers and anyone interested in popular science and philosophy.

Kepler's Physical Astronomy is an account of Kepler's reformulation of astronomy as a physical science, and of his successful use of (incorrect) physics as a guide in his astronomical discoveries. It presents the only reliable account of the internal logic of Kepler's so-called first and second laws, showing how and to what extent Kepler thought he had derived them from his physical principles. It explains for the first time Kepler's attempt to use an obscure discovery of Tycho Brahe to unify and confirm all of his own physical theories. It also describes the intricate (and neglected) theory which Kepler developed to account for the additional anomalies needed for the theory of the moon.

Romanticism in all its expression communicated a vision of the essential interconnectedness and harmony of the universe. The romantic concept of knowledge was decidedly unitary, but, in the period between 1790 and 1840, the special emphasis it placed on observation and research led to an unprecedented accumulation of data, accompanied by a rapid growth in scientific specialization. An example of the tensions created by this development is to be found in the scientists' congresses which attempted a first response to the fragmentation of scientific research. The problem concerning the unitary concept of knowledge in that period, and the new views of the world which were generated are the subject of this book. The articles it contains are all based on original research by an international group of highly specialized scholars. Their research probes a wide range of issues, from the heirs of Naturphilosophie, to the life sciences', and to the debate on Baconian Sciences', as well as examining many aspects of mathematics, physics and chemistry. History of philosophy and history of science scholars will find this book an essential reference work, as well as all those interested in 19th century history in general. Undergraduate and graduate students will also find here angles and topics that have hitherto been largely neglected.

It was not long ago that phrenology was commonly dismissed with amused contempt. However, recent scholarship now views it as one of the most significant, if curious, social and intellectual manifestations of the nineteenth century. It is seen as having impinged on virtually every aspect of life, thought and belief and is regarded as having contributed instrumentally to developments in anthropology, criminology, medicine, psychiatry and education. Many eminent figures of the period are also now appreciated as having seriously occupied themselves with phrenology, from sociologists Comte and Spencer to novelists such as Eliot and Balzac. This set of eight volumes draws together a wealth of material crucial to the intellectual debate over phrenology, both as a branch of mental physiology and as a contribution to the history of philosophy. The articles selected represent the variety of different views throughout the nineteenth century, both pro and anti-phrenology.

This book illuminates how Berkner became a model that produced the scientist/advisor/policymaker that helped build post-war America. It does so by providing a detailed account of the personal and professional beliefs of one of the most influential figures in the American scientific community; a figure that helped define the political and social climates that existed in the United States during the Cold War.

Women engineers have been in the public limelight for decades, yet we have surprisingly little historically grounded understanding of the patterns of employment and education of women in this field. Most studies are either policy papers or limited to statistical analyses. Moreover, the scant historical research so far available emphasizes the individual, single and unique character of those women working in engineering, often using anecdotal evidence but ignoring larger issues like the patterns of the labour market and educational institutions.
Richly illustrated, "Crossing Boundaries, Building Bridges" offers answers to the question why women engineers have required special permits to pass through the male guarded gates of engineering and examines how they have managed this. It explores the differences and similarities between women engineers in nine countries from a gender point of view. Through case studies the book considers the mechanisms of exclusion and inclusion of women engineers f

Women engineers have been in the public limelight for decades, yet we have surprisingly little historically grounded understanding of the patterns of employment and education of women in this field. Most studies are either policy papers or limited to statistical analyses. Moreover, the scant historical research so far available emphasizes the individual, single and unique character of those women working in engineering, often using anecdotal evidence but ignoring larger issues like the patterns of the labour market and educational institutions.
Crossing Boundaries, Building Bridges offers answers to the question why women engineers have required special permits to pass through the male guarded gates of engineering and examines how they have managed this. It explores the differences and similarities between women engineers in nine countries from a gender point of view. Through case studies the book considers the mechanisms of exclusion and inclusion of women engineers.

Vitalism is usually associated with Romantic theories of nature, but the supposition of a 'vital principle' or life-force recurred throughout eighteenth-century natural philosophy, to counter the inadequacy of mechanism to understand the operation of natural life. This book traces the persistent presence of a language of vital nature not only in eighteenth-century science, but in literary and philosophical writing too: in moral philosophy, theories of sensibility and political economy, and in the radical journalism and women's writing of the 1790s. It explores the influence of the Scottish vitalist physiology of Robert Whytt and others on writers and thinkers as diverse as Adam Smith, David Hume, Erasmus Darwin, John Hunter, John Thelwall and Mary Wollstonecraft. In doing so, it shows the centrality of vitalism to eighteenth-century accounts of the body, nature, matter and life, and offers a new way of understanding the relationship between eighteenth-century science and culture and that of the Romantic period.