Compulsive Eating Behavior and Food Addiction: Emerging Pathological Constructs is the first book of its kind to emphasize food addiction as an addictive disorder. This book focuses on the preclinical aspects of food addiction research, shifting the focus towards a more complex behavioral expression of pathological feeding and combining it with current research on neurobiological substrates. This book will become an invaluable reference for researchers in food addiction and compulsive eating constructs. Compulsive eating behavior is a pathological form of feeding that phenotypically and neurobiologically resembles the compulsive-like behaviors associated with both drug abuse and behavioral addictions. Compulsive eating behavior, including Binge Eating Disorder (BED), certain forms of obesity, and 'food addiction' affect an estimated 70 million individuals worldwide.

Photobiomodulation in the Brain: Low-Level Laser (Light) Therapy in Neurology and Neuroscience presents the fundamentals of photobiomodulation and the diversity of applications in which light can be implemented in the brain. It will serve as a reference for future research in the area, providing the basic foundations readers need to understand photobiomodulation's science-based evidence, practical applications and related adaptations to specific therapeutic interventions. The book covers the mechanisms of action of photobiomodulation to the brain, and includes chapters describing the pre-clinical studies and clinical trials that have been undertaken for diverse brain disorders, including traumatic events, degenerative diseases and psychiatric disorders.

The aim of this book is not only to introduce readers with a broad spectrum of biological actions of the NOP receptor, but also to feature a detailed look at the N/OFQ-NOP receptor system, medicinal chemistry, pharmacology, and clinical data of NOP-targeted ligands. This special volume book - for the first time focusing on the NOP receptor - is designed to serve as a useful reference, stimulate more research on the N/OFQ-NOP receptor system, and lead to more development of NOP-related ligands for several therapeutic applications.

Thermoregulation, Part II: From Basic Neuroscience to Clinical Neurology, Volume 155, not only reviews how body temperature regulation changes in neurological diseases, but also how this aspect affects the course and outcomes of each disease. Other sections of the volume review three therapeutic approaches that are aimed at manipulating body temperature, including induced hypothermia, induced hyperthermia and antipyretic therapy. The book is comprised of nine sections across two volumes, five dealing with the basic aspects of body temperature regulation and four dealing with the clinical aspects. Basic sections cover the Thermoregulation system, Thermoreceptors, Thermoeffectors, Neural pathways, and Thermoregulation as a homeostatic function. In addition, the book covers the physiology and neuroanatomy of the thermoregulation system and provides descriptions of how the regulation of body temperature intervenes with other physiological functions (such as sleep, osmoregulation, and immunity), stress, exercise and aging. Basic sections serve as an introduction to the four clinical sections: Body Temperature, Clinical Significance, Abnormal Body Temperature, Thermoregulation in Neurological Disease and Therapeutic Interventions.

Nervous System Drug Delivery: Principles and Practice helps users understand the nervous system physiology affecting drug delivery, the principles that underlie various drug delivery methods, and the appropriate application of drug delivery methods for drug- and disease-specific treatments. Researchers developing nervous system putative therapeutic agents will use this book to optimize drug delivery during preclinical assessment and to prepare for regulatory advancement of new agents. Clinicians will gain direct insights into pathophysiologic alterations that impact drug delivery and students and trainees will find this a critical resource for understanding and applying nervous system drug delivery techniques.

The Serotonin System: History, Neuropharmacology, and Pathology provides an up-to-date accounting on the physiology and pathophysiology of serotonin and the role it plays in behavioral functions. In addition, the book explores the potential roles of 5-HT1 in neurodevelopmental disorders and summarizes the history of the discovery and development of serotonergic drugs for the treatment of neuropsychiatric disorders. This concise, yet thorough, volume is the perfect introduction to this critical neurotransmitter. It is ideal for students and researchers new to the study of behavior, neuropsychiatry or neuropharmacology, but is also a great resource for established investigators who want a greater perspective on serotonin.

Neuroscience of the Nonconscious Mind includes novel concepts and insights on the brain mechanisms that control nonconscious mental functions, some of which were developed in the author's laboratory. The book describes neuroscience of conventional nonconscious mental functions, along with not so conventional functions like creativity, hypnosis and extrasensory perception, thus making it a very unique reference. This thought provoking book for students of mind, brain and consciousness will help explain concepts and introduce the science behind the nonconscious.

What difference is there between the visual experience of watching the moon in the sky and the visual experience of seeing a snake slither by your foot? It is easy to believe our interpretation of the world is split into a binary mode, between the bodily self and everything outside it. There is, however, a buffer zone in the immediate surrounding of the body, known as peripersonal space, in which boundaries are blurred. The notion of peripersonal space calls into question not only our entrenched theories of perception, but also has major implications on the way we perceive personal and social awareness. Research has yielded a vast array of exciting discoveries on peripersonal space, across a variety of disciplines: ethology, social psychology, anthropology, neurology, psychiatry, and cognitive neuroscience. The World at Our Fingertips: A Multidisciplinary Exploration of Peripersonal Space brings these perspectives together for the first time, as well as introducing a philosophical dialogue to the questions. Edited by a team of leading psychologists and philosophers in the fields of peripersonal space and bodily awareness, this comprehensive volume presents the reader with a fresh, accessible dialogue between authorities from vastly different areas of thought.

Neurosurgical Neuropsychology: The Practical Application of Neuropsychology in the Neurosurgical Practice comprehensively explains the use of neuropsychology in neurosurgical settings. The book covers various preoperative techniques that may benefit neurosurgeons, such as functional neuroimaging (fMRI, SPECT, MEG) for presurgical cognitive mapping, as well as more traditional methods to predict outcomes after surgery, including neurocognitive testing and the Wada procedure. The book's editors discuss why neuropsychologists add considerable value to the neurosurgical team. A wide range of patient populations are covered, ranging from Deep Brain Stimulation candidates for Parkinson's disease, to adult and pediatric epilepsy candidates and neuro-oncology cases. This book is ideal for neurosurgeons, neuropsychologists, neuro-oncologists, epileptologists, general neurologists, and others who want to know more about the use of neuropsychology as a tool in the presurgical and postoperative phases of neurosurgery.

Neuroinflammation, Second Edition, discusses the role inflammation plays in neuro-inflammatory diseases. As research in neuroinflammation has dramatically increased in recent years, this new edition covers all of the new developments and findings since the first publication nearly a decade ago. Comprehensive coverage of topics includes chapters on multiple sclerosis, optic neuritis and Susac syndrome. New chapters cover the latest research in Epilepsy and Neuroinflammation, Pediatric MS, Pediatric Lupus and Traumatic Brain Injury, amongst other topics. Inflammation is a central mechanism in many neurological diseases, including stroke, multiple sclerosis, brain trauma and meningitis, and it contributes to the generation of pain. Researchers are now beginning to understand the impact of the immune system on different nervous system functions and diseases, ranging from damage, through tolerance, and to modulation and repair.

Myasthenia Gravis and Myasthenic Disorders, Second Edition is a thoroughly re-written and updated version of the highly successful first edition published in 1999. The current edition begins with an overview of the anatomy and molecular architecture of the neuromuscular junction and the electrophysiologic diagnosis of its disorders. The introductory chapters are followed by a detailed exposition of the pathogenesis, natural history, diagnosis and therapy of the autoimmune myasthenias, the Lambert-Eaton myasthenic syndrome, and the increasingly complex and fascinating diseases collectively referred to as congenital myasthenic syndromes. The acetylcholine receptor is a major target of both autoimmune and inherited myasthenias and a separate chapter reviews its structural and functional properties. The book also describes disorders that often target terminal nerve segment near the neuromuscular junction-- the syndrome of peripheral nerve hyperexcitability and the Guillain-Barr syndrome.
Comprehensively written by leaders at the forefront of research, not to mention thoroughly referenced throughout and gorgeously illustrated, this new edition of the classic 1999 text will cement its place as the text on Myasthenia Gravis and related disorders for years to come.

Neurotechnology and Brain Stimulation in Pediatric Psychiatric and Neurodevelopmental Disorders provides a comprehensive overview of neurotechnological devices as potential treatments for psychiatric and neurodevelopmental disorders in children and adolescents. Many neuropsychiatric disorders are covered such as Autism Spectrum Disorder, ADHD, Depression, Tourette's Syndrome, and OCD. Different device-based treatments are discussed such as Transcranial Magnetic Stimulation, Transcranial Direct Current Stimulation, Deep Brain Stimulation, Chronotherapy, and Neurofeedback.

Handbook of Object Novelty Recognition, Volume 26, synthesizes the empirical and theoretical advances in the field of object recognition and memory that have occurred since the development of the spontaneous object recognition task. The book is divided into four sections, covering vision and perception of object features and attributions, definitions of concepts that are associated with object recognition, the influence of brain lesions and drugs on various memory functions and processes, and models of neuropsychiatric disorders based on spontaneous object recognition tasks. A final section covers genetic and developmental studies and gender and hormone studies.

Animal Models for Examining Social Influences on Drug Addiction, Volume 140 in the International Review of Neurobiology series, provides insights on social factors that mediate drug addiction. This book discusses current research and projects, with specific chapters focusing on Social Influences on Nicotine-related Behaviors in Rodents, Models of Alcohol Intake in Social Contexts, Social Factors in Ethanol Sensitization, Social Modulation of Heroin Intake, Amphetamines and Social Aspects of Addiction, Amphetamines and Social Aspects of Addiction, Social Models of Cannabis Use, Oxytocin and Rodent Models of Addiction, Social Place Preference and Reward, Social Defeat Stress, and more.

Neurobiology of the Placebo Effect, Part II, Volume 139, the latest release in the International Review of Neurobiology series, is the second part of a two-volume set that provides the latest placebo studies in clinically relevant models. Specific chapters cover the History of placebo effects in medicine, Lumping or Splitting: Towards a taxonomy of placebo and related effects, Theories and brain mechanisms of placebo analgesia, Pain Modulation: From CPM to placebo and nocebo effects in experimental and clinical pain, Modulation of the motor system by placebo and nocebo effects, and the role of sleep in learning placebo effects, amongst other topics.

Signal Processing for Neuroscientists, Second Edition provides an introduction to signal processing and modeling for those with a modest understanding of algebra, trigonometry and calculus. With a robust modeling component, this book describes modeling from the fundamental level of differential equations all the way up to practical applications in neuronal modeling. It features nine new chapters and an exercise section developed by the author. Since the modeling of systems and signal analysis are closely related, integrated presentation of these topics using identical or similar mathematics presents a didactic advantage and a significant resource for neuroscientists with quantitative interest. Although each of the topics introduced could fill several volumes, this book provides a fundamental and uncluttered background for the non-specialist scientist or engineer to not only get applications started, but also evaluate more advanced literature on signal processing and modeling.

Handbook of Ultrasonic Vocalization: Window into the Mammalian Brain, Volume 25, is an exhaustive resource on ultrasonic vocalizations in vertebrates, providing full coverage of all aspects of these vocalizations. The book also demonstrates the usefulness of ultrasonic vocalizations in studies of animal communication, sociobiological states, and in mammalian models of affective disorders, addictions and neurodevelopmental disorders, making it an indispensable resource for researchers using animal models. The book begins with the evolution of vocal communication before discussing mechanisms of ultrasound production, perception and the brain systems involved in emotional arousal that are responsible for the generation of vocalization and emotional states. In addition, the book covers studies of neuroactive agents and sociopsychological conditions that can regulate the outcome of ultrasonic vocalization and provide clues about animals' internal states. Critically, the book also includes thorough coverage of pharmacological investigations using ultrasonic vocalizations, increasingly being utilized for studies in affective disorders, psychoses, addiction and alcoholism. No other book provides such extensive coverage of this rapidly growing field of study.

Discover how 15 minutes a day can awaken your creative magic and spark joy

Have you ever been so absorbed in writing, drawing, cooking, dancing, yoga, music or crafting that you lost track of time? In neuroscience, this is known as ‘flow’, a focused state where the mind and body are at their most serene.

In this book, former dancer and neuroscientist Julia Christensen reveals why you experience overthinking and shares a 7-step method to create a reliable pathway to flow and effortlessly unlock the creative genius within you. Boost your mood, calm your mind, and enjoy the magic of flow every day.

This collaborative book by five distinguished scholars in overlapping fields suggests that fruitful living is extremely hard work and that social harmony requires the unlocking and the emancipation of the human brain - the core cerebral source for advancing human coherence, connectivity, cohesion and civility. The stakes are simply too high for stakeholders across our country not to respond to the ongoing and escalating crisis of human division and the desperate need for engagement, enlightenment, and acceptance of human diversity. The authors strongly encourage academic and practitioner psychologists, as well as other students and social scientists, to join a timely framed narrative for greater progress in diversity. Neurodiversity aims to encourage dialogue, discourse, and discovery about what may be obvious to many but avoided by most - because its forces us to look inward instead of outward. We can make such inward observations, through the lenses of psychology, cognition, mindfulness, and underleveraged brain capacity amid modern cultural neuroscience. This is critically important - particularly in a time marked by the widespread amplification of ambiguity, angst, ambivalence, and anger. This book focuses on "crucial thinking" versus "critical thinking." The authors pose fundamental questions -- about what we are calling a form of cognitive "levitation" and taxonomical "climbing" (CBDT) -- to think about purposes of intellectual discourse, not necessarily to seek empirical evidence. A special feature of this book is the inclusion of sample student learning outcomes as "provisos" throughout the narrative. We have attempted to integrate the student learning outcomes in the text's narrative and connect them to the sections where they are inserted for the reader. The book's embedded taxonomies can also facilitate the instruction, composition, and conceptualization of targeted student learning outcomes.

Medical Neurobiology, Second Edition continues the work of Dr. Peggy Mason as one of the few single author textbooks available. Written in an engaging style for the vast majority of medical students who will choose to specialize in internal medicine, orthopedics, oncology, cardiology, emergency medicine, and the like, as well as the student interested in neurology, psychiatry, or ophthalmology, this textbook provides a sturdy scaffold upon which a more detailed specialized knowledge can be built. Unlike other neuroscience textbooks, this new edition continues to focus exclusively on the human, covering everything from neuroanatomy to perception, motor control, homeostasis, and pathophysiology. Dr. Mason uniquely explains how disease and illness affect one's neurobiological functions and how they manifest in a person. Thoroughly updated as a result of student feedback, the topics are strictly honed and logically organized to meet the needs of the time-pressed student studying on-the-go. This textbook allows the reader to effortlessly absorb fundamental information critical to the practice of medicine through the use of memorable stories, metaphors, and clinical cases. Students will gain the tools and confidence to make novel connections between the nervous system and human disease. This is the perfect reference for any medical student, biology student, as well as any clinician looking to expand their knowledge of the human nervous system. New To the Second Edition of Medical Neurobiology: * New sections on cerebral palsy, brain cancer, traumatic brain injury, neurodegenerative diseases, aphasia, and Kallmann syndrome; * Incorporates easy to understand visual guides to brain development, eye movements, pupillary light reflex, pathways involved in Horner's syndrome; * Presents real-life dilemmas faced by clinicians are discussed from both the medical point of view and the patient's perspective; and * Additional reading lists are provided at the end of each chapter that include first-hand accounts of neurological cases and scientific discoveries (e.g. HM). Key Features Include: * Written in an accessible and narrative tone; * Uses metaphors and clinical examples to help the reader absorb the fundamentals of neurobiology; and * Highly illustrated with over 300 figures and tables for full comprehension of topics covered.

Neuropsychiatric manifestation in systemic lupus erythematosus (NPSLE) is one of the most recalcitrant complications of the disease. According to the 1999 ACR nomenclature and case definitions, diffuse psychiatric/neuropsychological syndromes in NPSLE (anxiety disorder, acute confusional state, cognitive dysfunction, mood disorder, psychosis) (diffuse NPSLE) present psychiatric manifestations unlike neurologic syndromes (focal NPSLE) originating from focal CNS lesions, such as cerebrovascular disease, demyelinating syndrome, headache, aseptic meningitis, chorea, seizures and myelopathy. A number of studies have reported that diffuse NPSLE is usually associated with the presence of autoantibodies against neuronal cells in serum as well as in cerebrospinal fluid (CSF). Moreover, IL-6 has been shown to be elevated in CSF of patients with diffuse NPSLE. Recently, it has been demonstrated that the severity of blood-brain barrier damages plays a crucial role in the development of acute confusional state, the severest form of diffuse NPSLE through the accelerated entry of larger amounts of autoantibodies to NMDA receptor subunit NR2 into the CNS. Since the importance of autoantibodies in the NPSLE has been now evident, such an aggressive treatment, especially B cell depleting therapy, would make sense in that it would reduce the levels of pathogenic autoantibodies, leading to a better prognosis of NPSLE. As far as we know, no single book specifically dedicated to NPSLE alone has been published as yet. As mentioned above, NPSLE constitutes a vastly expanding field of research with increasing numbers of papers published annually. Therefore, we believe that an effort to collect and critically review these publications is invaluable. Such an effort will provide an important contribution to basic researchers as well as clinicians working in the field of neurology, rheumatology, psychiatry and internal medicine fields.

This edited volume presents fundamentals as well as applications of oculomotor methods in industrial and clinical settings. The topical spectrum covers 1.) basics and background material, 2.) methods such as recording techniques, markov models, Levy flights, pupillometry and many more, as well as 3.) a broad range of applications in clinical and industrial settings. The target audience primarily comprises research experts and practitioners, but the book may also be beneficial for graduate students.