Asiatic Liver Fluke - From Basic Science to Public Health, Volume 102, is a well-known and respected outlet for detailed and comprehensive reviews written by experts covering all aspects of parasitology. This latest release covers topics of interest, including Plasmodium genetics: An approach to learn and end human, Leishmania tropica: what we know from experimental models, Extracellular vesicles in host-parasite interaction, Cathepsins and vaccines for fascioliasis, and Evolution in fungi and drug resistance.

First published in 1963, "Advances in Parasitology" contains comprehensive and up-to-date reviews in all areas of interest in contemporary parasitology.
"Advances in Parasitology" includes medical studies on parasites of major influence, such as "Plasmodium falciparum" and trypanosomes. The series also contains reviews of more traditional areas, such as zoology, taxonomy, and life history, which shape current thinking and applications.
Eclectic volumes are supplemented by thematic volumes on various topics, including control of human parasitic diseases and global mapping of infectious diseases. The 2010 impact factor is1.683.

* Informs and updates on all the latest developments in the field * Contributions from leading authorities and industry experts

A deeply reported, insightful, and literary account of humankind’s battles with epidemic disease, and their outsized role in deepening inequality along racial, ethnic, class, and gender lines—in the vein of Medical Apartheid and Killing the Black Body.

Epidemic diseases enter the world by chance, but they become catastrophic by human design.

With clear-eyed research and lush prose, A History of the World in Six Plagues shows that throughout history, outbreaks of disease have been exacerbated by and gone on to further expand the racial, economic, and sociopolitical divides we allow to fester in times of good health.

Princeton-trained historian Edna Bonhomme’s examination of humanity’s disastrous treatment of pandemic disease takes us across place and time from Port-au-Prince to Tanzania, and from plantation-era America to our modern COVID-19-scarred world to unravel shocking truths about the patterns of discrimination in the face of disease. Based on in-depth research and cultural analysis, Bonhomme explores Cholera, HIV/AIDS, the Spanish Flu, Sleeping Sickness, Ebola, and COVID-19 amidst the backdrop of unequal public policy. But much more than a remarkable history, A History of the World in Six Plaguesis also a rising call for change.

"The Biology and Identification of the Coccidia (Apicomplexa) of Turtles of the World" is an invaluable resource for researchers in protozoology, coccidia, and parasitology, veterinary sciences, animal sciences, zoology, and biology. This first-of-its-kind work offers a taxonomic guide to apicomplexan parasites of turtles that enables easy parasite identification, with a summary of virtually everything known about the biology of each known parasite species. It is an important documentation of this specific area, useful to a broad base of readers, including researchers in biology, parasitology, animal husbandry, diseases of wild and domestic animals, veterinary medicine, and faculty members in universities with graduate programs in these areas.

There are about 330 turtle species on Earth; many are endangered, a growing number of species are kept as pets, and some are still used as food by humans. Turtles, like other vertebrate animals have many different kinds of parasites (viruses, bacteria, protozoa, worms, arthropods, and others). Coccidiosis in turtles has prevented large-scale turtle breeding, and represents a serious problem in need of control. This succinct and highly focused book will aid in that effort.
Offers line drawings and photomicrographs of each parasite from each hosts speciesProvides methods of identification and treatmentPresents a complete historical rendition of all known publications on coccidia (and their closest relatives) from all turtle species on Earth, and evaluates the scientific and scholarly merit of eachProvides a complete species analysis of the known biology of every coccidian described from turtles Reviews the most current taxonomy of turtles and their phylogenetic relationships needed to help assess host-specificity and evaluate what little cross-transmission work is available

"Approaches to Research on the Systematics of Fish-Borne Trematodes" is a concise guide for systematic studies of the prevalence of fish-borne trematodes both in the endemic areas and experimental laboratories. It includes methods to identify species of fish-borne trematodes to enhance the precision of research studies based on the metacercarial stage.

Misidentification of trematode species is a common occurrence when researchers are new to the field and have no guidance. Consequentially, sometimes publications report inaccurate prevalence rates of these parasites. This compact guide gives clear direction on: Collection of parasites in the final hostsCollection of cercaria from snail first intermediate hostsCollection of metacercaria from fish hostsMolecular identification of parasitesSystematics of fish-borne trematodes
Provides research guidelines and protocols for studying systematics of fish-borne trematodes using both morphological and molecular dataPresents keys to enable identification of metacercariae of fish-borne trematodes in the Greater Mekong subregion

Macrocyclic lactones are chemical compounds that represent the main treatment for parasitic diseases of animals, not only for helminth infections, but also a number of major ectoparasitic infestations. There has been no comprehensive book on this subject for more than a decade and this book fills this gap and provides detailed coverage of the basic science of these drugs and their mode of action, as well as their clinical use in farm and companion animals and in humans.

"The Biology and Identification of the Coccidia (Apicomplexa) of Rabbits of the World" is a taxonomic summation of a damaging intestinal parasite found in rabbits and transmissible to other species, including humans. This book conceptually and historically summarizes the world's literature on the parasite and also provides a quick guide to isolation procedures, identification, strategies for management, and available chemotherapy. It is a vital source of knowledge about coccidia s real and potential transmission to humans, which can lead to dangerous health problems, like severe dehydration, vomiting, lethargy and even death.

Coccidiosis is an intestinal disease that affects several different animal species, including canines and humans, and is one of the most prevalent protozoal infections in North America. The causative agent is a protozoan that has the ability to multiply rapidly and cause major damage in the intestinal wall, rupturing the cells of the intestinal lining. The final stage, the oocyst, is extremely resistant to environmental stress and is difficult to completely remove from the environment. Oocysts are frequent contaminants of feed and water and when the sporulated oocysts are ingested by other animals, they start the life cycle over in the new host. With the demand for rabbits in scientific research and for rabbit meat for human consumption increasingly globally each year, rabbits are of epidemiologic significance for laboratory workers, university researchers, veterinarians, pet owners, and breeders.
Evaluates the scientific and scholarly merit of each of the publications written about coccidian from every rabbit species, providing a complete historical renditionA treatise for the identification of coccidia and their treatment as neededWritten in a style that can be understood by most educated lay persons and laboratory workersWritten by the first ranked author team among the world-class parasitologists who study coccidiaCombined in one single source, this book follows the gold standards in coccidian biology and identificationBrings all that information together in one volume and solves the problems faced by researchers, veterinarians, students and others in trying to find and navigate through this scattered literature"

This book tackles a number of different perspectives concerning the parasitic helminth Ascaris, both in animals and in humans and the disease known as ascariasis. It seeks to identify interesting, exciting and novel aspects, which will interest readers from a broad range of disciplines. Over a quarter of the world's population are infected with the human roundworm, and the equivalent in pigs is equally ubiquitous. Both contribute to insidious and chronic nutritional morbidity, and this has been quantified, in humans, as disability adjusted life years approximating 10.5 million. Ascaris larvae develop in host parenteral tissues, and the resultant pathology has been condemnation. Ascariasis, despite its staggering global prevalence and the sheer numbers of people it infects, remains a classic neglected disease. However, renewed interest in the consequences of early infection with worms from the perspective of immune modulation, co-infections and the development of allergy further enhances the relevance of these parasites.
Brings together a wide range of topics and approaches and recent, comprehensive and progressive researchconcerning the neglected parasite Ascaris

Provides a blueprint of how a single parasite entity can stimulate interest in basic biology, clinical science, veterinary science, public health and epidemiology

Presents awealth of new insights given that a book on this parasite has not been published for over 20 years

16 chapters from a range of top authors from around the world "

The second part of an updated edition of the classic "Methods in Cell Biology, "Volume 48, this book emphasizes diverse methods and technologies needed to investigate "C. elegans," both as an integrated organism and as a model system for research inquiries in cell, developmental, and molecular biology, as well as in genetics and pharmacology. By directing its audience to tried-and-true and cutting-edge recipes for research, this comprehensive collection is intended to guide investigators of "C. elegans" for years to come.
Diverse, up-to-date techniques covered will be useful to the broadening community of "C. elegans" researchers for years to comeChapters written by leaders in the fieldTried and true methods deliver busy researchers a one-stop compendium of essential protocols

Parasites threaten the health of animals and humans alike. Especially in times of increasing globalization and global warming, parasites can enlarge their "kingdom" by spreading. At the same time many of the existing medical products have become ineffective. As these products have been used for many decades, parasites have developed resistances, so that they have progressed in their fight for survival. Therefore it is obvious that humans must develop new methods to face these dangers. Thus parasitological knowledge increases daily and must be formulated to be accessible for as many parasitologists (veterinarians, physicians, biologists) as possible. Therefore it is necessary that reviews reflecting the present status of the progress in many fields of research be published. Therefore this book, published on the occasion of the 50th anniversary of the German Society of Parasitology, compiles 18 reviews on recent "hot topics," including a new vaccine against malarial parasites; severe diseases with poor chances of treatment (cryptosporidiosis, coccidiosis, theileriosis); vectors (mosquitoes, ticks) and their transmission activities; and fish parasites, including molecular insights into the sex of parasites with a focus on the survival abilities that made them so dangerous. These chapters provide detailed information for researchers, as well as for teachers and students in parasitology.

An updated edition of the classic "Methods in Cell Biology" volume 48, this book emphasizes diverse methods and technologies needed to investigate "C. elegans," both as an integrated organism and as a model system for research inquiries in cell, developmental, and molecular biology, as well as in genetics and pharmacology. By directing its audience to tried-and-true and cutting-edge recipes for research, this comprehensive collection is intended to guide investigators of "C. elegans" for years to come.

*Diverse, up-to-date techniques covered will be useful to the broadening community of "C. elegans" researchers for years to come * Chapters written by leaders in the field * Tried and true methods deliver busy researchers a one-stop compendium of essential protocols

Parasitoids are parasitic insects that kill their insect hosts in immature pre-reproductive stages. Parasitoids are employed in biological control programs worldwide to kill insect pests and are environmentally safe and benign alternatives to chemical pesticides. As resistance to chemical pesticides continues to escalate in many pest populations, attention is now refocusing on biologically-based strategies to control pest species in agriculture and forestry as well as insect vector populations that transmit human and animal diseases. Parasitoids are an economically critical element in this equation and integrated pest management.

Viruses have evolved intimate associations with parasitoids, and this book features sections on both symbiotic viruses that are integrated into the wasp s chromosomal DNA (polydnaviruses) that play critical roles in suppressing host immunity during parasitism. A separate section with additional chapters on viral pathogens that infect parasitoids to cause disease and act as detrimental agents that limit effectiveness of wasp species employed in biological control of pests is also featured. A third component is a section on parasitoid venoms, which are of interest to the pharmaceutical and medical communities as well as insect-oriented biologists.
Sections focus on both virus evolution and genomics as well as proteomics and functional roles of polydnavirus-encoded gene productsInternational researchers and emerging leaders in their fields provide readers with syntheses of the latest researchIncludes content on both symbiotic viruses and pathogenic viruses, plus new research on parasitoid venomsCutting-edge section on future directions in the field covers the impacts of polydnavirus research on medicine, human health, bioengineering and the economy, increasing the value for researchers and practitioners who need to stay on top of the research in this swiftly moving field"

Cytometry is one of the most rapidly growing methodologies available for basic cell and molecular biology, cytogenetics, immunology, oncology, environmental sciences and also various fields of clinical medicine. Thisnew edition, split into 2 Parts, is an almost completely new book, with nearly all of the chapters devoted to new topics. Like the previous volumes on cytometry published as part of the Methods in Cell Biology series, it provides a comprehensive description of particular cytometric methods and reviews their applications. Chapters present the theoretical foundations of the described methods, their applicability in experimental laboratory and clinical settings, and describes common traps and pitfalls such as problems with data interpretation, comparison with alternative assays, and choosing the optimal assay.
* Comprehensive presentation of cytometric methods covering theoretical applications, applicability, potential pitfalls, and comparisions to alternative assays
* Discusses many new assays developed since the previous edition
* Presents recent developments in cytometric intrumentation/technology"

This volume critically reviews all previously published work of parasites that interact with krill (order Euphausiacea) updating misconceptions and summarizing the diversity of epibionts, ectoparasites, mesoparasites and endoparasites that interact with these crustaceans. As far as we know, there is a lack of books about parasites of marine crustaceans not targeted to fisheries and aquaculture. Thus, this would be the most complete and integrative monograph of parasites of marine zooplankton and micro nektonic organisms worldwide. Krill form immense aggregations and serve as food for multiple planktonic and nektonic predators playing a crucial role in pelagic food web. Besides, several species are also used for human consumption. For these reasons there is a growing concern about the health issues that krill parasites may impose on other species, including us. This book provides a comprehensive review of parasites of a crustacean order that can extrapolate to potential parasites in other crustacean taxa worldwide.

Nature helps... of course at first itself by developing measures that give bacteria, fungi, plants and animals a chance to be successful in their struggle for life. As a latecomer on Earth, Homo sapiens was gifted with some droplets of the divine spirit of recognition and thus became able to observe, to analyse and recombine skills of other living beings and to use them for his overwhelming career over the last 10,000 years.Of course fungi, plants, animals and even bacteria were primarily used by mankind as food or as lifestyle products such as beer, but soon it became clear that there was much more potential hidden in these organisms and that they could be used for other purposes, too. Extracts of plants and fungi were recognized as powerful remedies, as medicines, as insecticides or acarizides, as repellents against parasites or even as weapons, e.g. when poisonous compounds from frogs or plants were applied to arrowheads. Over the last 110 years the pharmaceutical industry has often simulated nature by analyzing complex organic substances taken from living organisms and then producing by synthesis absolutely pure compounds, which mostly consisted of only one single active substance. These products had the advantage of acting against precisely one target and thus produced fewer possible side effects than the complex plant extracts. However, the more serious side effect was that disease agents could develop resistances to pure medicinal products much more easily. Thus after 70 years of excellent prospects for chemotherapy, some dark clouds appeared and quickly gathered, so that several therapeutic remedies now no longer work. Therefore in many countries - especially in those where the pure chemotherapeutics are too expensive for the poor population - the cry "back to nature" is becoming louder and louder. This has led to an enormous increase of studies that again use natural extracts as remedies in the fight against diseases. The present book summarizes examples of promising aspects in a broad spectrum of applications and shows how extracts derived from bacteria, marine organisms, plants or even animals may help to treat infectious diseases, how such organisms may keep away parasites and pests from the bodies of plants or animals, including humans, and how they can be used directly to aid in diagnosis, promote wound healing and even to help catch criminals. These 15 chapters offer not only basic research on these different fields, but also show how useful and effective products can be developed from research.

In biological terms, a parasite can be defined as a oean organism that grows, feeds and is sheltered on, or in, a different organism while contributing nothing to the survival of the host.a 1 This relationship is particularly intimate for parasitic protozoa (and single-celled fungi such as the Microsporidia), many of which not only penetrate tissue barriers, but gain entry into host cells. The entry mechanisms are as diverse as the organisms employing them and are often critical components of their pathogenic profile. All of the parasitic organisms highlighted in this new book represent medically important human pathogens that contribute significantly to the global burden of disease. As such there is intense interest in understanding the molecular basis of infection by these pathogensa "not only with regard to their clinical relevance but also the fascinating biology they reveal. For most of the parasites discussed here (Plasmodium falciparum, Toxoplasma gondii, Cryptosporidium parvum, Trypanosoma cruzi and Leishmania spp.) the ability to penetrate biological barriers and/or to establish intracellular residence is critical to survival of the pathogen in the mammalian hosts. For other parasites, such as Entamoeba, a tissue invasive phenotype is a key virulence determinant. In the ensuing 18 chapters, select members of this diverse set of protozoan parasites, as well as some examples of the extremely reduced fungal parasites classified as Microsporidia, are discussed within the context of the fascinating molecular strategies employed by these organisms to migrate across biological barriers and to establish residence within target host cells.

The study of parasitic organisms at the molecular level has yielded fascinating new insights of great medical, social, and economical importance, and has pointed the way for the treatment and prevention of the diseases they cause. Biochemistry and Molecular Biology of Parasites presents an up-to-date account of this modern scientific discipline in a manner that allows and encourages the reader to place the biochemistry and molecular biology of these organisms in their biological context. The chapters are cross-referenced and grouped in an arrangement that provides a fully integrated whole, and permits the reader to create a composite of the biochemical function of these organisms.
Individual chapter includes those devoted to metabolism, in both aerobic and anaerobic protozoa; antioxidant mechanisms; parasite surfaces; organelles; invasion mechanisms; and chemotherapy. The helminths are discussed not only from the point of view of their cellular biochemistry and metabolism, but also with respect to both their integrated functions such as neurochemistry, structure and functions of surfaces, and reproduction. Written by expert investigators, this book will be of interest to all experienced researchers, graduate students, and to the newcomer eager to become familiar with the biochemistry and molecular biology of parasites.

Hepatitis viruses research started more than fifty years ago. The names of hepatitis A and hepatitis B were introduced in 1947 when it became clear that there were two types of hepatitis that were transmitted either enterically or parenterally. It became apparent in the 1970's that there were additional hepatitis viruses distinct from hepatitis A and hepatitis B, and thus, the term non-A, non-B hepatitis was introduced. The non-A, non-B hepatitis was further divided into post-transfusion non-A, non-B hepatitis and enterically-transmitted non-A, non-B hepatitis in the 1980's. By the end of the 1980's, both post-transfusion non-A, non-B virus and enterically-transmitted non-A, non-B virus had been identified and renamed hepatitis C virus and hepatitis E virus, respectively. Hepatitis delta antigen was first recognized as an antigen associated with hepatitis B virus infection in the 1970's. In the early 1980's, a virus was isolated and named hepatitis delta virus. These five different hepatitis viruses have distinct replication pathways and are major health concerns. They have become an important topic for teaching to graduate-level and medical students. Hepatitis Viruses provides a comprehensive, up-to-date review of these viruses to readers. Each chapter is written by one of the top researchers in the field, and topics include: the epidemiology and the natural history of infection of these viruses, the molecular biology and the replication cycle of individual hepatitis viruses, host-virus interactions and the pathogenesis of hepatitis viruses, the immunology of hepatitis viruses, the relationship between hepatitis viruses and hepatocellular carcinoma, the viral vaccines and antiviral drugs. This book can serve as a supplemental reading material to graduate students and medical students, and to any researcher who would like to learn more about hepatitis viruses.

Parasitic diseases remain a major health problem throughout the world, for both humans and animals. For many of us, our technologically advanced lifestyle has decreased the prevalence and transmission of parasitic diseases, but for the majority of the world's population, they are ever present in homes, domestic animals, food, or the environment. The study of parasites and parasitic disease has a long and distinguished history. In some cases, it has been driven by the great importance of the presence of the parasite to the community, for example, those that affect our livestock. In other cases, it is clear that applied research has suffered for lack of funding because the parasite affects people with few resources, such as the rural poor in resource-poor countries. These instances include the so-called "neglected diseases," as defined by the World Health Organization (WHO). Parasites have complicated life cycles, and a thorough understanding of the unique characteristics of a particular parasite species is vital in attempts to avoid, prevent, or cure infection or to alleviate symptoms. Of course, the biological characteristics that each parasite has developed to aid survival and transmission, to avoid destruction by the immune system, and to adapt to a changing environment are of lasting fascination to basic biologists as well. The elegance of these biological systems has ensured that the study of protozoan and metazoan parasites also remains an active field of research in countries where the diseases are not a threat to the population.

Leishmania is a vector-borne pathogenic parasite found in 88 countries worldwide and is the causative agent of leishmaniasis. The different Leishmania species infect macrophages and dendritic cells of the host immune system, causing symptoms that range from disfiguring cutaneous and mucocutaneous lesions, widespread destruction of mucous membranes, or visceral disease affecting the haemopoetic organs. The recent publication of the complete genome sequences of three different Leishmania species provides new insights into this leading pathogen and presents scientists with an exciting resource to improve the understanding of its complex molecular and cellular biology. In this book, internationally recognized Leishmania experts critically review the most important aspects of current Leishmania research, providing the first coherent picture of the organism's molecular and cellular biology since the publication of the genome sequence. Chapters are written from a molecular and genomic perspective and discuss in depth Leishmania-specific aspects of trypanosomatid biology and pathology. Topics include: diagnosis and epidemiology, genome structure and content, regulation of gene expression, the Leishmania proteome, the Leishmania metabolome, Leishmania differentiation, interaction with the sand fly vector, drug discovery, drug resistance, and much more. This will be essential reading for all researchers working with Leishmania, trypanosomes, and protozoa; and is recommended for all biology and medical libraries.

Parasitic nematodes (Nematoda) represent an important group of fish parasites. Many species are highly pathogenic, often causing serious diseases or even death to their fish hosts. The significance of recognizing these parasites increases with the development of aquaculture in many countries and with transcontinental transfers of fish. A prerequisite for developing effective control measures in fish culture is the exact identification of these parasites, as well as a knowledge of their, frequently complicated, host-parasite-environment relationships. The present monograph is the first to deal in detail with all nematodes which are parasites on European freshwater fish, providing contemporary knowledge of the taxonomy, biology and ecology of these parasites. This book is divided into introductory chapters, including general morphological, biological and ecological data on fish nematodes, their pathogenicity and methods of study; systematic part/species descriptions, data on hosts, localization, distribution and life cycles and bionomy of all species systematically arranged; and a host-nematode parasite list. This publication is intended for parasitologists, veterinarians, workers in fisheries, university students. It will also be of interest to ichthyologists, museum curators and those engaged in nature conservation.

The soil-transmitted nematode parasites, or geohelminths, are - called because they have a direct life cycle, which involves no intermediate hosts or vectors, and are transmitted by faecal contamination of soil, foodstuffs and water supplies. They all inhabit the intestine in their adult stages but most species also have tissue-migratoryjuvenile stages, so the disease manifestations they cause can therefore be both local and systemic. The geohelminths together present an enormous infection burden on humanity. Those which cause the most disease in humans are divided into three main groupings, Ascaris lumbricoides (the large roundworm), Trichuris trichiura (whipworm), and the blood-feeding hookworms (Ancylostoma duodenale and Necator americanus ), and this book concentrates on these. These intestinal parasites are highly prevalent worldwide, A. lumbricoides is estimated to infect 1471 million (over a quarter ofthe world's population), hookworms 1277 million, and T. trichiura 1049 million. The highly pathogenic Strongyloides species might also be classified as geohelminths, but they are not dealt with here because the understanding of their epidemiology, immunology and genetics has not advanced as rapidly as for the others. This is primarily because of the often covert nature of the infections, with consequent difficulties for analysis. If there is ever a second edition of this book, then there will hopefully be much to say about this infection.

All important aspects of thermophilic moulds such as systematics, ecology, physiology and biochemistry, production of extracellular and intracellular enzymes, their role in spoilage of stores products and solid and liquid waste management, and general and molecular genetics have been dealt with comprehensively by experts in this book which covers progress in the field over the last 30 years since the seminal book Thermophilic Fungi published by Cooney and Emerson in 1964. The experts have reviewed extensive literature on all aspects of thermophilic moulds in a very comprehensive manner. This book will be useful for graduates as well as post-graduate students of life sciences, mycology, microbiology and biotechnology, and as a reference book for researchers.

Parasites evolve under selective pressures which are different from those acting on free-living organisms. The aim of this textbook is to present these pressures and to show how they have shaped the ecology of parasites over evolutionary time. Broad theoretical concepts are explained simply and clearly and illustrated throughout with example organisms. The book will be an invaluable text for advanced undergraduate biologists who are studying evolutionary biology, ecology, population biology, parasitology and evoluationary ecology. It will also prove to be a valuable reference to postgraduate students and researchers in the same fields.

Helminths include one of the most diverse and geographically widespread groups of parasites which infect humans and animals. About 100 species have been reported from humans, usually producing asymptomatic infection or mild symptoms. However, about 20 species are of public health importance causing severe or even fatal infections. In many parts of Africa parasitic helminths are responsible for enormous economic losses, hampering rural development programmes and reducing the pace of economic growth. Many parasitic helminths are either zoonoses (diseases naturally transmitted between vertebrate animals and man) or have evolved from animal parasites. The modification of the environment through wars, famine and the ever expanding and increasingly mobile human population brings people into close contact with new environments and wildlife species which makes the study and control of zoonoses of special interest and complexity. In Africa, the transmission of helminth parasites is highly influenced by the ever changing social and cultural differences between diverse groups of peoples and their interaction with wild and domestic animals. It is not surprising, therefore, that approaches to the study and control of parasitic zoonoses require intersectoral cooperation between physicians, veterinarians, parasitologists, zoologists, demographers, anthropologists, engineers and economists to provide the breadth of knowledge and expertise required to develop our understanding of these diseases and to devise methods for their control. This book provides a selective compilation of parasitic helminths, many of which are zoonoses which create important economic and public health problems in Africa.