Although the histological typing of ovarian tumours is the focus of this volume, other aspects of investigation of a specimen of ovarian tumour are also important. Some of these aspects are mentioned in the text or illustrated. They include tumour grading, which is impor- tantprognostically and therapeutically for certain types ofovarian tu- mour, quantification ofcomponents in mixed tumours and evaluation of the stroma of certain tumours that are associated with endocrine function. Grading methodologies have varied from one tumour type to another and from one group of investigators to another for the same type of tumour. Because a standard internationally recognized grading methodology has not been established, no specific guidance is presented in this volume. Nevertheless, grading by any generally acceptable method should be incorporated in the diagnosis whenever appropriate. The clinical and pathological classification of the extent of tu- mour growth (staging) should be taken into account for the purposes of treatment and prognosis. The TNlV1/FIGO system is therefore in- cluded (p. 45). Histological Classification of Ovarian Tumours 1 Surface Epithelial-Stromal Tumours 1. 1 Serous tumours 1. 1. 1 Benign 1 1. 1. 1. 1 Cystadenoma 8441/0 Papillary cystadenoma 8460/0 1. 1. 1. 2 Surface papilloma ...8461/0 1. 1. 1. 3 Adenofibroma; cystadenofibroma ...9014/0 1. 1. 2 Of borderline malignancy (of low malignant potential) 2 1. 1. 2. 1 Cystic tumour 8442/1 Papillary cystic tumour ...846211 Surface papillary tumour...8463/1 1. 1. 2. 2 1. 1. 2. 3 Adenofibroma; cystadenofibroma 9014/1 1. 1.

Quantities, Symbols, Units, and Abbreviations in the Life Sciences is a reliable compilation of the most up-to-date recommendations for using units, symbols, abbreviations, and acronyms in scientific publications across the biological sciences. Drawing on the authority of the various nomenclature committees of the many international societies in the biosciences, as well as on the editors of prestigious scientific journals, and on eminent individuals active in scientific publishing, this essential reference provides authors and editors with easy access to the authoritative usage of the universally accepted terms they need for clear scientific communication. The compiled symbols, units, and abbreviations are defined, with commentary and some etymological background frequently provided. The diverse scope of disciplines treated includes biochemistry, molecular biology, medicine, genetics, immunology, and virology, plus appropriate sections on mathematics, physics, and chemistry.

This is a histological classification of tumours and tumour-like lesions of the exocrine pancreas which also includes those tu- mours showing a mixture of exocrine and endocrine elements. The classification is based principally on standard microscopic observations, but whenever indicated it incorporates diagnosti- cally valuable immunohistological findings. In addition, the most important immunohistological findings which are helpful in cat- egorizing pancreatic tumours are summarised in Table 1. The major guideline of this classification scheme is the group- ing of the pancreatic exocrine tumours according to their biologi- cal behaviour. Thus, the neoplasms are broadly divided into benign (adenoma) and malignant tumours (carcinoma). How- ever, in recent years we have learned that this division is not a sharp but rather a gradual transition. We therefore added a third group which we call "tumours of uncertain malignant potential" representing a borderline category analogous to that recognized for some ovarian tumours. This group includes mucinous cystic tumour, intraductal papillary-mucinous tumour and solid- pseudopapillary tumour. These neoplasms are defined by the grade of dysplasia and/or potential to become malignant. Mucinous cystic tumours of uncertain malignant potential, for instance, exhibit moderate epithelial dysplasia, but do not show severe dysplasia/carcinoma in situ changes, nor carcinomatous invasion of the cyst wall or the adjacent pancreatic tissue. Solid- pseudopapillary tumour has a benign looking histological ap- pearance, but metastases may occur. Biologically, all these neoplasms are primarily slow-growing lesions and have an excel- lent prognosis when adequately treated by complete resection.

The task of updating the classification was given to the Classification and Nomenclature Committee of the International Society of Gynecological Pathologists and its four subcommittees. This classification reflects the present state of knowledge and modifications are almost certain to be needed as experience accumulates. Since many of the tumours and tumour-like conditions in the classification occur in several sites in the female genital tract, cross-referencing from one site to another has been done in illustrating these lesions.

The first edition of Histological Typing of Soft Tissue Tumours, pub- lished in 1969, represented a major step in the standardization of nomen- clature in this specialty area. Accompanied by a glass slide set of more than a hundred common and exotic tumours, this book resulted in the rapid assimilation of a universal set of guidelines and diagnostic defini- tions by pathologists in many countries. In the intervening two decades numerous changes have occurred, and our committee has been chal- lenged by the desire to incorporate new and exciting findings from the areas of immunohistochemistry and molecular biology into the classifi- cation with the need to develop a simple reproducible classification for practising pathologists. The current system, while based principally on standard microscopic observations, acknowledges and cites the use of di- agnostically valuable ancillary techniques. Changes in the Classification Although the original classification utilized the concept of "histogene- sis" or tissue of origin in defining tumours, we have departed from that point of view, acknowledging the impossibility of determining histogen- esis by morphologic means alone. This classification is based on the "line of differentiation", or stated simply, by comparing tumours to the nor- mal cell they most closely resemble without necessarily implying origin therefrom. As in the old classification we have interpreted the term "tu- mours" in the broadest sense of the word and have, therefore, included neoplastic and non-neoplastic conditions.

The fourth edition of the TNM Classification was published in 1987,1 and a revision in 1992.2 It was the result of efforts by all national TNM Committees towards a worldwide uniform classification. The classifica tion criteria are identical with the fourth edition of the Manual for 3 Staging of Cancer of the American Joint Committee on Cancer (AJCC). Although the classification has found wide acceptance, some workers have pointed out that individual definitions and rules for staging are not sufficiently detailed. This can lead to inconsistent application of the clas sification. the antithesis of standardization. This source of differences in interpretation applies not only to the classification of individual organs but also to the general rules of the system, especially to the definitions of the requirements for the pathological classification (pT, pN). These are specified only for carcinoma of the breast; for other sites, reference must be made back to the general rules. which can lead to variable interpreta tions. The TNM Project Committee of the UICC has addressed this prob lem and collected and considered the criticisms and suggestions from the national TNM Committees as well as from cancer registries, oncolo gical associations and individual users. The result was the decision to complement the 4th edition of the TN M Classification 1.2. 3 with the publi cation of a TNM Supplement containing recommendations for the uni form use of TNM."

units have been included. References, which now number approximately 650, have been brought up to date. The most recently accepted values of the physical constants have been provided. Our thanks go to all those who, since the fifth edition, have helped in this revision by suggestions. In particular the authors express their gratitude to Jane M. Jerrard who, with enthusiasm, put the text into a computer and eliminated the editorial scissors and paste and simplified the onerous and long task of producing a text from the fragmented material of the revision. In the preface to the fifth edition it was suggested that the book provided at that time the most complete and up-to-date information of its kind available. The authors again make the same claim for this sixth edition. H. G. JERRARD D. B. McNEILL Warsash Newtownards Southampton Northern Ireland England Preface to the first edition The intense specialization that occurs in science today has meant that scientists working in one field are often not familiar with the nomenclature used by their colleagues in other fields. This is particularly so in physics. This dictionary is designed to help overcome this difficulty by giving information about the units, dimensionless numbers and scales which have been used, or are still being used, throughout the world. Some four hundred entries are provided and these are supplemented by about five hundred references. The definition of each entry is given together with relevant historical facts.

The Fifth Report of the International Committee on Taxonomy of Viruses (ICTV), summarizes the proceedings and decisions reached by the ICTV at its meetings held at the International Congresses of Virology in Sendai (1984), Edmonton (1987) and Berlin (1990). This report has been organized in the same way as the previous ones (Wildy, 1971; Fenner, 1976; Matthews, 1979; 1982), yet it encompasses many more families and groups of viruses than previous reports, and it includes new tables, diagrams and keys. The officers and members of the ICTV study groups from 1984 to 1990 are listed, as the current ICTV statutes and rules of nomenclature. Information on the format for submission of new taxonomic proposals to the ICTV is also provided. Since the Fourth Report of the ICTV (1982), 19 new virus families and groups have been described. This report includes 2,430 viruses belonging to 73 families or groups, as well as virus satellites and viroids descriptions, but it does not include descriptions not approved by the ICTV. It now will be possible to publish such preliminary, and in some cases controversial, descriptions in the Virology Division pages of the Archives of Virology --this will allow virologists to carry on the kind of interim dialogue that is necessary for arriving at broad agreement on taxonomic matters.

Science communication is a rapidly expanding area and meaningful engagement between scientists and the public requires effective communication. Designed to help the novice scientist get started with science communication, this unique guide begins with a short history of science communication before discussing the design and delivery of an effective engagement event. Along with numerous case studies written by highly regarded international contributors, the book discusses how to approach face-to-face science communication and engagement activities with the public while providing tips to avoid potential pitfalls. This book has been written for scientists at all stages of their career, including undergraduates and postgraduates wishing to engage with effective science communication for the first time, or looking to develop their science communication portfolio.

The "raison d'etre" of hierarchical dustering theory stems from one basic phe nomenon: This is the notorious non-transitivity of similarity relations. In spite of the fact that very often two objects may be quite similar to a third without being that similar to each other, one still wants to dassify objects according to their similarity. This should be achieved by grouping them into a hierarchy of non-overlapping dusters such that any two objects in ne duster appear to be more related to each other than they are to objects outside this duster. In everyday life, as well as in essentially every field of scientific investigation, there is an urge to reduce complexity by recognizing and establishing reasonable das sification schemes. Unfortunately, this is counterbalanced by the experience of seemingly unavoidable deadlocks caused by the existence of sequences of objects, each comparatively similar to the next, but the last rather different from the first."

The original suggestion to organize a symposium about the classi fication and evolution of the Flowering Plants was made at, the International Botanical Congress at Leningrad in 1975, and the idea was so well accepted by several colleagues that plans for such a symposium quickly took shape. An organizing committee consisting of Professor H. MERXMULLER, Miinchen, Professor V. H. HEYWOOD, Reading, and Professor K. KUBITZKI, Hamburg, was set up. The conference took place on 7-12 September 197tl in the Institut fiir Allgemeine Botanik of the University of Hamburg under the auspices of the International Association for Plant Taxonomy and was at tended by 80 participants from 14 countries. There have been several meetings in recent years which have dealt with the origin and evolution of the Flowering Plants so that it might be questioned whether yet another symposium dealing with more or less the same subject were really "justified. As the reader will see from the contents of the book, this symposium differed from similar ones held recently in two respects: 1. Emphasis was given to methodological aspects of the classification of higher taxa, and 2. much classificatory and evolutionary evidence relating to the higher taxa of Flowering Plants was presented."

This book constitutes a unique source of hard-copy information on mouse variants and is an essential work of reference for biologists who use mouse genetic strains and variants in their research. The third edition reflects the great expansion of knowledge in the field in recent years, and includes new chapters and data. As in earlier editions, the main chapter provides a catalogue of all known mouse genes. Genetic maps are supported by a large table of data on recombination fractions.

People have been interested in knots at least since the time of Alexander the Great and his encounter with the Gordian knot. There are famous knot illustrations in the Book of Kells and throughout traditional Islamic art. Lord Kelvin believed that atoms were knots in the ether and he encouraged Tait to compile a talbe of knots about 100 years ago. In recent years, the Jones polynomial has stimulated much interest in possible relationships between knot theory and physics. The book is concerned with the fundamental question of the classification of knots, and more generally the classification of arbitrary (compact) topological objects which can occur in our normal space of physical reality. Professor Hemion explains his classification algorithm - using the method of normal surfaces - in a simple and concise way. The reader is thus shown the relevance of such traditional mathematical objects as the Klein bottle or the hyperbolic plane to this basic classification theory. The Classification of Knots and 3-dimensional Spaces will be of interest to mathematicians, physicists, and other scientists who want to apply this basic classification algorithm to their research in knot theory.

Covering a range of metaphors from a diverse field of sciences, from cell and molecular biology to evolution, ecology, and biomedicine, Understanding Metaphors in the Life Sciences explores the positive and negative implications of the widespread use of metaphors in the biological and life sciences. From genetic codes, programs, and blueprints, to cell factories, survival of the fittest, the tree of life, selfish genes, and ecological niches, to genome editing with CRISPR's molecular scissors, metaphors are ubiquitous and vital components of the modern life sciences. But how exactly do metaphors help scientists to understand the objects they study? How can they mislead both scientists and laypeople alike? And what should we all understand about the implications of science's reliance on metaphorical speech and thought for objective knowledge and adequate public policy informed by science? This book will literally help you to better understand the metaphorical dimensions of science.

Biologist Carol Kaesuk Yoon explores the historical tension between evolutionary biology and taxonomy. Carl Linnaeus struggled in the eighteenth century to define species in light of their mutability while still relying on intuitive, visual judgments. As taxonomy modernized, it moved into labs, yielding results counterintuitive to humanity s innate predisposition to order the world. By conceding scientific authority to taxonomists, Yoon argues, we ve contributed to our own alienation from nature."

Embracing more than 5,000 genera, distributed in 425 families and 46 orders, Malcolm C. McKenna and Susan K. Bell's "Classification of Mammals" is the most comprehensive work to date on the systematics, relationships, and occurrences of all mammal taxa, living and extinct, down through the rank of genus.

Since George Gaylord Simpson's 1945 classification, the paleontological record has been recalibrated, and the intervening years have seen much debate and progress concerning the theoretical underpinnings of systematization. McKenna inherited the project from Simpson and, with Bell, has constructed a completely updated hierarchical system that reflects the genealogy of Mammalia.

The first IUPAC Manual of Symbols and Terminology for Physicochemical Quantities and Units was published in 1969 with the objective of 'securing clarity and precision, and wider agreement in the use of symbols, by chemists in different countries, among physicists, chemists and engineers, and by editors of scientific journals'. Subsequent revisions have taken account of many developments in the field and were also substantially expanded and improved in presentation in several new editions of what is now widely known as the ‘Green Book of IUPAC’. This abridged version of the forthcoming 4th edition reflects the experience of the contributors and users of the previous editions. The book has been systematically brought up to date and provides a compilation of generally used terms and symbols with brief, understandable definitions and explanations. Tables of important fundamental constants and conversion factors are included. In this abridged guide, the more specialized and complex material has been omitted, retaining, however, the essence of the Green Book. It is particularly intended to be suitable for students and teachers but it should also be useful for scientists, science publishers and organizations working across a multitude of disciplines requiring internationally approved terminology in the area of Physical Chemistry. It now includes the most up to date definitions and constants in agreement with the ‘new SI’ as established by agreement on the International System of Units in Paris in 2019. It should find the widest possible acceptance and use for best practice in science and technology.

This new edition of a foundational text presents a contemporary review of cladistics, as applied to biological classification. It provides a comprehensive account of the past fifty years of discussion on the relationship between classification, phylogeny and evolution. It covers cladistics in the era of molecular data, detailing new advances and ideas that have emerged over the last twenty-five years. Written in an accessible style by internationally renowned authors in the field, readers are straightforwardly guided through fundamental principles and terminology. Simple worked examples and easy-to-understand diagrams also help readers navigate complex problems that have perplexed scientists for centuries. This practical guide is an essential addition for advanced undergraduates, postgraduates and researchers in taxonomy, systematics, comparative biology, evolutionary biology and molecular biology.

This text can be read at many levels. Not least it is an extraordinary inventory - an illustrated summary of all the Earthly creatures that have ever lived. Whatever living thing you come across, from E-coli to an oak tree or an elephant, this book will show you what kind of creature it is, and how it relates to all others. Yet there are far too many creatures to present merely as a catalogue. The list of species already described is vast enough - nearly two million - but there could in reality be as many as 30 million different animals, plants, fungi and protists - and perhaps another 400 million different bacteria and archaea. In the 4000 million years or so since life first began on Earth, there could have been several thousand billion different species. The only way to keep track of so many is to classify - placing similar creatures into categories, which nest within larger categories, and so on. As the centuries have passed, so it has become clear that the different groups are far more diverse than had ever been appreciated. Thus Linneus in the 18th century placed all living things in just two kingdoms, Animals and Plants.

How do you describe an analytical method, measure the purity of the new chemical that you have just synthesized, or report the proper units of measurement? For analytical chemists, the principal tool of the trade, or source of terms, is this book - the so-called Orange Book. First published in 1978, this latest edition takes into account the explosion of new analytical procedures and, at the same time, the diversity of techniques and the quality and performance characteristics of the procedures that are the focus of interest. The scope of analytical chemistry has widened, new types of instrumental techniques have emerged and automation has taken over. Answers can now be shared, not only on the chemical composition and structure of the sample, but also changes in composition and structure in space and time. New chapters on chemometrics, bio-analytical methods of analysis, and sample treatment and preparation have been added. The terminology of metrology and quality assurance is now up to date with the latest ISO and JCGM standards. This new volume will be an indispensable reference resource for the coming decade, revising and updating accepted terminology, and providing the official language of analytical chemistry.

This second part of Volume 48 of the Flora of Pan-Himalaya is devoted to the single genus, Saussurea of the Asteraceae family, which has wide medicinal applications. This is the largest family in the Pan-Himalaya, with 235 species, 149 of which are endemic to the Pan-Himalaya. Saussurea is a notoriously difficult, largely Asiatic, genus with often indistinct species boundaries. Many new species of Saussurea were described in the course of preparing this account. The nomenclatural novelties in this volume include five changes in status, and 17 new synonyms. 27 lectotypes are newly designated. During the research for this volume, the author and his team described 40 new species of Saussurea, and these, along with numerous new designations and classifications, are recorded here for the first time.

The ultimate aim of IUPAC nomenclature is to provide unequivocal and comprehensible names for all kinds of chemical structures. This requires a rational basis from which comprehensible names can be developed. Written by leading world authorities this second edition of Principles of Chemical Nomenclature outlines IUPAC recommendations for application in the principle branches of chemistry: organic, inorganic, organometallic, and polymer. It also includes some basic biochemical nomenclature. The book clearly explains the fundamental principles of nomenclature methods and enables the reader to apply them accurately and with confidence. New developments are described and additional nomenclature systems used in specific industries are introduced. The book is replete with examples for guidance and there are extensive tables to direct the reader to information quickly. Aimed at chemistry teachers and students at all levels, it advises on the best presentation of formulae and chemical graphics. Although rather advanced for school pupils, their teachers will find it useful.

Chemical nomenclature is used to identify a chemical species by means of written or spoken words and enables a common language for communication amongst chemists. Nomenclature for chemical compounds additionally contains an explicit or implied relationship to the structure of the compound, in order that the reader or listener can deduce the structure from the name. This purpose requires a system of principles and rules, the application of which gives rise to a systematic nomenclature. Of course, a wide range of traditional names, semisystematic or trivial, are also in use for a core group of common compounds. Detailing the latest rules and international practice, this new volume can be considered a guide to the essential organic chemical nomenclature, commonly described as the "Blue Book". An invaluable source of information for organic chemists everywhere and the definitive guide for scientists working in academia or industry, for scientific publishers of books, journals and databases, and for organisations requiring internationally approved nomenclature in a legal or regulatory environment.

The "Handbook of Proteins" provides scientists and students with a focused and accessible resource covering all aspects of protein biochemistry. It describes traditional and state-of-the-art techniques for elucidating protein function and structure. Derived from the acclaimed "Encyclopedia of Life Sciences" Presented in full-colour throughout Assembles more than 200 peer-reviewed articles, written by top scientists in each field The articles are reliable, self-contained and cross-referenced throughout Almost all aspects of protein structure, function, and chemistry are illuminated by one or more articles Numerous articles also provide an introduction to methods for purifying proteins, determining their structures and properties, and cataloguing them in databases Dozens of additional articles detail important aspects of enzymatic catalysis and protein-ligand interactions

The "Handbook of Proteins" is a comprehensive and authoritative resource for teachers, students and researchers in the molecular life sciences. The easy layout encourages frequent retrieval.

From subarctic tundra to equatorial rainforest, deep in the soil and at the tip of the highest tree, ants are found the world over. This book, by the world's leading ant taxonomist, offers a definitive guide for identifying these ubiquitous insects.

Barry Bolton provides identification keys to all the living ant subfamilies and genera, presented in alphabetical order and separated by zoogeographical region. Designed for professional and amateur myrmecologists alike, this guide is as accessible as it is comprehensive, including information on the function and use of identification keys, instructions for preparing specimens for examination, and an illustrated glossary of morphological terms. Over 500 scanning electron microscope photographs illustrate the taxonomic keys.

Bolton introduces each subfamily with a diagnosis of the group, followed by synoptic classifications of all genera within each subfamily, notes on broad distribution, and a list of references to all species-rank publications useful to identification. He also provides a short summary of the extinct subfamilies and includes a checklist of every name ever proposed in the classification of ants, from the rank of family down to subgenus, showing the current status and usage of each.

An updated and exhaustively expanded revision of the taxonomic keys found in Hö lldobler and Wilson's "The Ants," Bolton's identification guide takes its place alongside that landmark work as the foundation for the study of ants for many years to come.