This book, edited by leading experts in radiology, offers a state-of-the-art overview of the specifics and the added value of dual-energy, multi-energy, and spectral computed tomography (CT). Latest advances and upcoming innovations such as photon-counting detector CT are covered by renown experts in the field. The entire spectrum of clinical applications of dual-energy and spectral CT throughout the body is covered. Book chapters are written by expert authors with a background in physics and radiology and are richly illustrated with high quality figures, graphical illustrations, and tables. The first section covers background issues and the most relevant technical aspects of the technique, including a detailed description of the approaches to dual-energy, spectral and photon-counting CT by different vendors of CT scanners. The second part focusses on the use of dual-energy, spectral and photon-counting CT in daily clinical practice, and individual chapters are devoted to imaging of the brain, cardiovascular system, gastrointestinal tract, abdominal organs, skeletal system, and the chest. The focus of the book ensures that it will be of interest for a multidisciplinary forum of readers comprising radiologists, medical physicists, and other medical professionals and scientists being interested in cutting-edge CT imaging.

This book focuses on applications of micro CT, CBCT and CT in medicine and engineering, comprehensively explaining the basic principles of these techniques in detail, and describing their increasing use in the imaging field. It particularly highlights the scanning procedure, which represents the most crucial step in micro CT, and discusses in detail the reconstruction process and the artifacts related to the scanning processes, as well as the imaging software used in analysis. Written by international experts, the book illustrates the application of micro CT in different areas, such as dentistry, medicine, tissue engineering, aerospace engineering, geology, material engineering, civil engineering and additive manufacturing. Covering different areas of application, the book is of interest not only to specialists in the respective fields, but also to broader audience of professionals working in the fields of imaging and analysis, as well as to students of the different disciplines.

Written by experts in the field of ophthalmology, this new text assists in understanding new imaging technology and the clinical information it can provide. It allows the reader to review numerous images of various pathologies and would be of interest to retina specialists and ophthalmologists. Retinal imaging has undergone dramatic changes in the last decade, characterized by constantly improving image resolution, most notably, as it applies to macular diseases, thanks to ever evolving optical coherence tomography. However, imaging retina outside of the vascular arcades has come a long way with advent of new cameras and lenses. The most profound change has been the introduction of wide-angle angiography, which has demonstrated pathologies previously not seen or suspected and gives rise to new theories of pathophysiology of some retinal diseases. Understanding this new imaging technology and the clinical information it can provide requires a basis of knowledge and experience in associating the findings with other clinical signs in the eye and the rest of the body. Atlas of Wide-Field Retinal Angiography and Imaging helps with this experience by allowing the reader to review numerous images of various pathologies and analyzes angiographic findings in the retinal periphery. Furthermore, as this technology increasingly fills ophthalmologists' offices around the world, this book will prove to be an invaluable resource, written by experts in the field for retina specialists and ophthalmologists.

This book gives a clinical context to optical coherence tomography (OCT) findings, while considering the differential diagnosis and providing patient management guidance. Relevant anatomical and technical aspects are discussed, followed by a pragmatic illustration of the use of OCT for the clinical spectrum of multiple sclerosis and optic neuritis, and finishing with information on monitoring ocular side effects of recently approved disease-modifying treatments in multiple sclerosis. Optical Coherence Tomography in Multiple Sclerosis: Clinical Applications is aimed at clinical neurologists working with patients suffering from MS and general neurologists who see patients with visual symptoms in their daily practice. Ophthalmologists sharing clinical responsibilities with neurologists for patients under disease-modifying treatments will also find the book of interest.

Recent research has identified the assessment of myocardial perfusion and viability as another promising CT application for the comprehensive diagnosis of coronary heart disease. In this book, the first to be devoted to this novel application of CT, leading experts from across the world present up-to-date information and consider future directions. After short sections outlining the state of the art in the traditional applications of CT to image structure and function, the full range of CT techniques that may be employed to evaluate the myocardial blood supply are discussed in detail. Similarly, diverse CT approaches for the assessment of myocardial viability are described, with careful consideration of the available experimental and clinical evidence and the role of quantitative imaging. Protocol recommendations that will be of invaluable practical assistance are also provided.

This richly illustrated book presents the pediatric applications of PET/CT in the full range of scenarios frequently encountered in a professional setting. It opens with a thorough introduction covering the fundamental science and the clinical basis for use of PET/CT in this age group. Pitfalls and artifacts are examined, and normal variations and benign findings are carefully described. Each subsequent chapter addresses the role of PET/CT with different radiopharmaceuticals in the evaluation and management of a specific disease. The full range of oncological diseases is covered, including the rare ones. Succinct descriptions of clinical cases are included and, when appropriate, comparisons are made with other modalities. In addition, the role of PET/CT in biopsy guidance and in radiation therapy planning is explained. This book will be invaluable for residents and practitioners in nuclear medicine, radiology, oncology, radiation oncology, and nuclear medicine technology.

CT of the Acute Abdomen provides an in-depth and comprehensive account of the use of CT in patients with acute abdomen. Recent significant developments in CT that are of relevance in imaging of the acute abdomen, including multislice CT and multiplanar reconstructions, receive particular attention. CT features are clearly illustrated, and pitfalls and differential diagnoses are discussed. The first section of the book presents epidemiological and clinical data in acute abdomen. The second and third sections document the key CT findings and their significance and discuss the technological background, including acquisition, reformatting, and surface and volume rendering. The fourth and fifth sections, which form the main body of the book, examine in detail the various clinical applications of CT in nontraumatic and traumatic acute abdomen. Full account is taken of new trends in the diagnosis and management of patients with acute abdomen, and the role of CT is examined in this context. This book will serve as an ideal guide to the performance and interpretation of CT in the setting of the acute abdomen; it will be of value to all general and gastrointestinal radiologists, as well as emergency room physicians and gastrointestinal surgeons.

The field of nuclear medicine has evolved rapidly in recent years, and one very important aspect of this progress has been the introduction of hybrid imaging systems. PET-CT has already gained widespread acceptance in many clinical settings, especially within oncology, and now SPECT-CT promises to emulate its success. Useful applications of this new approach have been identified not only in oncology but also in endocrinology, cardiology, internal medicine, and other specialties. This atlas, which includes hundreds of high-quality images, is a user-friendly guide to the optimal use and interpretation of SPECT-CT. The full range of potential SPECT-CT applications in clinical routine is considered and assessed by acknowledged experts. The book is designed to serve as a reference text for both nuclear physicians and radiologists; it will also provide fundamental support for radiographers, technologists, and nuclear medicine and radiology residents.

Dual-energy CT is a novel, rapidly emerging imaging technique which offers important new functional and specific information. In this book, physicists and specialists from different CT manufacturers provide an insight into the technological basis of, and the different approaches to, dual-energy CT. Renowned medical scientists in the field explain the pathophysiological and molecular background of the technique, discuss its applications, provide detailed advice on how to obtain optimal results, and offer hints regarding clinical interpretation. The main focus is on the use of dual-energy CT in daily clinical practice, and individual sections are devoted to imaging of the vascular system, the thorax, the abdomen, and the extremities. Evaluations and recommendations are based on personal experience and peer-reviewed literature. Plenty of carefully chosen high-quality images are included to illustrate the clinical benefits of the technique. Content Level Professional/practitioner Keywords Computed Tomography - Dual Energy CT - Functional Imaging - Spectral Imaging Related subjects Cardiology & Angiology - Internal Medicine - Radiology

Make sure you're prepared for the ARRT CT exam for computed tomography exam. The thoroughly updated Mosby's Exam Review for Computed Tomography, 3rd Edition serves as both a study guide and an in-depth review. Written in outline format this easy-to-follow text covers the three content areas on the exam: patient care, imaging procedures, and physics/instrumentation. Three 160-question mock exams are included in the book along with an online test bank of more than 600 questions that can be randomly sampled to create unlimited variations. You will never take the same test twice! For additional remediation, all questions have rationales that can be viewed in quiz mode. A thorough, outline-format review covers the four content areas on the computed tomography advanced certification exam: patient care, safety, imaging procedures, and CT image production. Mock exams in the book and on the Evolve website prepare students for the ARRT exam, with three 160-question mock exams in the book and 700 questions on Evolve that may be randomly accessed for an unlimited number of exam variations. Online study aids allow students to bookmark questions for later study, see rationales for correct and incorrect answers, get test tips for different questions, and record and date-stamp your test scores Review questions with answers help students prepare for the ARRT exam and identify areas that need additional study. Rationales for correct and incorrect answers provide students with the information they need to make the most out of the Q&A sections. NEW! Technological focus on reducing patient radiation exposure includes the latest dose-related guidelines. NEW! Updated content reflects the latest ARRT CT exam specifications NEW! 50 new CT images demonstrate need-to-know pathologies in detail NEW! Thoroughly revised and updated information detail the major technological advances in the field of Computed Tomography

This book covers the state-of-the-art research on advanced high-resolution tomography, exploring its role in regenerative medicine. and also explores the 3D interactions between tissues, cells, and biomaterials. Various multidisciplinary paths in regenerative medicine are covered, including X-ray microtomography and its role in regenerative medicine, synchrotron radiation-based microtomography and phase contrast tomography, the challenge of the vascularization of regenerated tissues, lung and cartilage imaging, and more. This is an ideal book for biomedical engineers, biologists, physicists, clinicians, and students who want to pursue their studies in the field of regenerative medicine. This book also: Reviews in detail the algorithms and software used for the 3D exploration of regenerated tissue Covers the latest research on the use of X-ray microtomography for muscle diseases Details applications of synchrotron radiation tomography in orthopedics and dentistry

This book highlights important techniques for cellular imaging and covers the basics and applications of electron tomography and related techniques. In addition, it considers practical aspects and broadens the technological focus by incorporating techniques that are only now becoming accessible (e.g. block face imaging). The first part of the book describes the electron microscopy 3D technique available to scientists around the world, allowing them to characterize organelles, cells and tissues. The major emphasis is on new technologies like scanning transmission electron microscopy (STEM) tomography, though the book also reviews some of the more proven technologies like electron tomography. In turn, the second part is dedicated to the reconstruction of data sets, signal improvement and interpretation

By showing us the human brain at work, PET (positron emission tomography) scans are subtly--and sometimes not so subtly--transforming how we think about our minds. "Picturing Personhood" follows this remarkable and expensive technology from the laboratory into the world and back. It examines how PET scans are created and how they are being called on to answer myriad questions with far-reaching implications: Is depression an observable brain disease? Are criminals insane? Do men and women think differently? Is rationality a function of the brain?

Based on interviews, media analysis, and participant observation at research labs and conferences, Joseph Dumit analyzes how assumptions designed into and read out of the experimental process reinforce specific notions about human nature. Such assumptions can enter the process at any turn, from selecting subjects and mathematical models to deciding which images to publish and how to color them. Once they leave the laboratory, PET scans shape social debates, influence courtroom outcomes, and have positive and negative consequences for people suffering mental illness. Dumit follows this complex story, demonstrating how brain scans, as scientific objects, contribute to our increasing social dependence on scientific authority.

The first book to examine the cultural ramifications of brain-imaging technology, "Picturing Personhood" is an unprecedented study that will influence both cultural studies and the growing field of science and technology studies.

This issue of PET Clinics focuses on PET/MRI: Advances in Instrumentation and Quantitative Procedures. Articles will include: Advances in clinical PET/MRI instrumentation; Magnetic resonance imaging-guided attenuation correction of positron emission tomography data in PET/MRI; Magnetic resonance imaging-guided partial volume correction of positron emission tomography data in PET/MRI; Magnetic resonance imaging-guided derivation of the input function for PET kinetic modeling; Innovations in small-animal PET/MRI instrumentation; Dual-modal PET/MRI molecular imaging probes; Magnetic resonance imaging-guided motion compensation of positron emission tomography data in PET/MRI; Attenuation correction for MR coils in combined PET/MR imaging; and more!

Computed Tomography gives a detailed overview of various aspects of computed tomography. It discusses X-ray CT tomography from a historical point of view, the design and physical operating principles of computed tomography apparatus, the algorithms of image reconstruction and the quality assessment criteria of tomography scanners. Algorithms of image reconstruction from projections, a crucial problem in medical imaging, are considered in depth. The author gives descriptions of the reconstruction methods related to tomography scanners with a parallel X-ray beam, trough solutions with fan-shaped beam and successive modifications of spiral scanners. Computed Tomography contains a dedicated chapter for those readers who are interested in computer simulations based on studies of reconstruction algorithms. The information included in this chapter will enable readers to create a simulation environment in which virtual tomography projections can be obtained in all basic projection systems. This monograph is a valuable study on computed tomography that will be of interest to advanced students and researchers in the fields of biomedical engineering, medical electronics, computer science and medicine.

This book provides a detailed overview on the use of global optimization and parallel computing in microwave tomography techniques. The book focuses on techniques that are based on global optimization and electromagnetic numerical methods. The authors provide parallelization techniques on homogeneous and heterogeneous computing architectures on high performance and general purpose futuristic computers. The book also discusses the multi-level optimization technique, hybrid genetic algorithm and its application in breast cancer imaging.

This issue of Dental Clinics updates topics in CBCT and Dental Imaging. Articles will cover: basic principles of CBCT; artifacts interfering with interpretation of CBCT; basic anatomy in the three anatomic planes of section; endodontic applications of CBCT; pre-surgical implant site assessment; software tools for surgical guide construction; CBCT for the nasal cavity and paranasal sinuses; CBCT and OSA and sleep disordered breathing; update on CBCT and orthodontic analyses; liabilities and risks of using CBCT; reporting findings in a CBCT volume, and more!

Nuclear Medicine is a diagnostic modality which aims to image and in some cases quantify physiological processes in the body to highlight disease or injury. Within nuclear medicine, over the past few decades, major technological changes have occurred and concomitantly changes in the knowledge and skills required have had to evolve. One of the most significant technological changes has been the fusion of imaging technologies, to create hybrid systems such as SPECT/CT, PET/CT and PET/MR. With these changes in mind, Practical SPECT/CT in Nuclear Medicine provides a handy and informative guide to the purchase, clinical implementation and routine use of a SPECT/CT scanner. Practical SPECT/CT in Nuclear Medicine will be a valuable resource for all personnel working in nuclear medicine and it will be of particular value to trainees.

Oncological imaging has thoroughly changed in the past decade, especially due to the introduction of PET and 18FDG. In "Positron Emission Tomography," expert referring specialists and professional imagers seek to help bridge some of the knowledge gaps in several oncological domains. The book s goal is to aid in the improvement of communicative competences: to communicate scan findings so that the referring specialist receives proper advice from the imager, and that, alternatively, the referring one provides the imager with appropriate clinical details to allow for a proper interpretation, and that the referring specialist is aware of the possibilities and limitations of the requested technology. While it focuses on FDG PET, other radiopharmaceuticals are covered as well, where appropriate. Written for the highly respected "Methods in Molecular Biology " series, this volume provides the kind of detailed description and implementation advice that is crucial for getting optimal results.

Authoritative and convenient, "Positron Emission Tomography" serves as an excellent reference for oncologists, surgeons, radiotherapists, radiologists, nuclear medicine physicians, and pathologists desiring a stronger synergy within their vital efforts."

Computed Tomography gives a detailed overview of various aspects of computed tomography. It discusses X-ray CT tomography from a historical point of view, the design and physical operating principles of computed tomography apparatus, the algorithms of image reconstruction and the quality assessment criteria of tomography scanners. Algorithms of image reconstruction from projections, a crucial problem in medical imaging, are considered in depth. The author gives descriptions of the reconstruction methods related to tomography scanners with a parallel X-ray beam, trough solutions with fan-shaped beam and successive modifications of spiral scanners. Computed Tomography contains a dedicated chapter for those readers who are interested in computer simulations based on studies of reconstruction algorithms. The information included in this chapter will enable readers to create a simulation environment in which virtual tomography projections can be obtained in all basic projection systems. This monograph is a valuable study on computed tomography that will be of interest to advanced students and researchers in the fields of biomedical engineering, medical electronics, computer science and medicine.

This book presents the proceedings of the 13th International Conference on Electrical Bioimpedance, ICEBI 2007, combined with the 8th Conference on Electrical Impedance Tomography, held at the Graz University of Technology in Graz, Austria, in August 2007.

Neurological applications of PET include using it to identify Alzheimer's Disease, including differentiating between other forms of Dementia, to show causes of seizures that were otherwise unclear, and to diagnose psychiatric disorders like Schizophrenia. Although other books on PET may have a chapter or section on neurological applications, this is the only comprehensive and up-to-date book on neurological PET. It reviews PET in neuroscience with particular emphasis on findings that indicate its potential for improving diagnosis and treatment in neurology and psychiatry. Improving the transfer of the huge scientific developments in brain PET into clinical care will produce tangible human benefit. To this end, NeuroPET focuses on practical and potentially clinically relevant issues and identify solid ground as well as open questions. In addition, the book includes major chapters on the methodological background, including tracer physiology and kinetic modeling, and a comprehensive literature review. Included in this extremely useful package is a CD-ROM that features video clips and interactive navigation in 3D data sets that illustrate the information contained in PET images in major neurological diseases and its potential to improve diagnosis and neurosurgical planning in brain tumors.

A comprehensive and contemporary reference work covering the basic science and clinical applications of positron emission tomography. This book reflects the tremendous increase in interest in PET as both a clinical and research imaging modality in the past 10 years. Written by experts in the field and edited by those involved in PET development, and training of scientists and medical specialists. Positron Emission Tomography - basic science and clinical practice thoroughly explains the principles, clinical applications and economic aspects of PET today. Chapters go into detail on PET applications in oncology, the central nervous system, cardio-respiratory systems, infectious diseases and pediatrics. Discussions are also found on technology design and evaluation, PET in drug discovery and development in imaging gene expression and therapy. Peter E. Valk MB BS FRACP is based in the Northern California PET Imaging Center, Sacramento, CA USA, Dale L. Bailey PhD FIPEM ARCP is based in the Department of Nuclear Medicine, Guy's Hospital, London UK, David W. Townsend PhD is based in the Department of Radiology, University of Pittsburgh, Pittsburgh, PA USA, Michael N. Maisey MD FRCP FRCR is Professor at the Department of Radiological Sciences, Guy's Hospital, London UK.

PET in Clinical Oncology describes the use of Positron Emission Tomography (PET) in the diagnosis and management of malignant tumors. Experts from Germany and the United States present basics, technical details, and clinical aspects for both standard and new PET techniques. The book illustrates the importance of PET in comparison to other imaging techniques.
Generously supplemented with charts, tables, and illustrations, each chapter provides the reader with well-delineated descriptions, from the basic technical situation through the clinical use of PET. This book is helpful to all those dealing with the diagnosis and therapy of cancer.