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Books > Medicine > Clinical & internal medicine > Cardiovascular medicine
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Optical Coherence Tomography in Cardiovascular Research (Hardcover)
Loot Price: R5,044
Discovery Miles 50 440
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Optical Coherence Tomography in Cardiovascular Research (Hardcover)
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Given that for centuries, the standard tool to understand diseases
in tissues was the microscope and that its major limitation was
that only excised tissue could be used, recent technology now
permits the examination of diseased tissue in vivo. Optical
coherence tomography (OCT) has promising potential when applied to
coronary artery disease. OCT has the capability to identify
coronary plaque and to distinguish between plaques that are stable
and unstable. If the plaques are stable then OCT can direct
percutaneous intervention (angioplasty or stenting). Optical
coherence tomography is a light-based imaging technology that
allows for very high resolution imaging in biological tissues. It
has been first applied in ophthalmology, where it soon became the
golden standard for the assessment of (epi-) retinal processes. The
unique imaging capabilities have raised the interest of researchers
and clinicians in the field of cardiovascular disease, since OCT
offers unique possibilities to study atherosclerosis
pathophysiology in vivo. With over 1.1M Americans having a heart
attack this year because of unstable plaque rupture, OCT may have
an increasingly important role in the early diagnosis of coronary
artery disease. This unique publication offers the reader the basic
background to OCT and its role in the diagnosis and management of
coronary artery disease. The Handbook of Optical Coherence
Tomography in Cardiovascular Research introduces the cardiovascular
application of this technology. Clinicians, biologists, engineers
and physicist are discussing different aspects of cardiovascular
OCT application in a multidisciplinary approach. The handbook
offers the readership a concise overview on the current state of
the art of vascular OCT imaging and sheds light on a variety of
exciting new developments. The physics, technical principles of OCT
and its application in a broad spectrum of cardiovascular research
areas are summarized by highly recognized specialists. The
potential of OCT in peripheral and coronary arteries and in
developmental cardiology are described. Each research area is
introduced by a clinical expert in the field followed by discussion
of different aspects from an engineering, biomedical and clinical
perspective. Specifically, the current capabilities for plaque
characterization, detection of vulnerable plaque, guidance of
interventional procedures, Doppler-assessment, and molecular
contrast imaging are being described. The Handbook of Optical
Coherence Tomography in Cardiovascular Research targets researchers
and clinicians involved in the field of atherosclerosis. The
summary of basic physics, engineering solutions, pre-clinical and
clinical application covers all relevant aspects and will be a
valuable reference source.
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