Molecular Signalling: Ca2+-Signaling in Cardiac Myocytes: Evidence from Evolutionary and Transgenic Models; M. Morad, Y.J. Suzuki. Diastolic Viscoelastic Properties of Rat Cardiac Muscle; Involvement of Ca2+; B.D.M.Y. Stuyvers, et al. The Contractile Mechanism and Energetics: Molecular Control of Myocardial Mechanics and Energetics: The Chemo-Mechanical Conversion; A. Landesberg. Myocardial Cell Energetics; H. Kammermeier. Cardiac Mechanics and Flow Dynamics: How Cardiac Contraction Affects the Coronary Vasculature; N. Westerhof, et al. Dynamic Interaction between Myocardial Contracton and Coronary Flow; R. Beyar, S. Sideman. Vascular Structure and Remodeling: Endothelial Gene Regulation by Laminar Shear Stress; N. Resnick, et al. Myocardial Structure and Function. Tissue Remodeling with Micro-Structurally Based Material Laws; P. Hunter, T. Arts. Electrical Activation and Propagation: Cardiac Excitation: An Interactive Process of Ion Channels and Gap Junctions; Y. Rudy, R.M. Shaw. The Cardionome: Concepts in Modeling: Design and Strategy for the Cardionome Project; J.B. Bassingthwaighte. 20 Additional Chapters. Index.

In Developmental Biology of the Sea Urchin and Other Marine Invertebrates: Methods and Protocols, expert researchers in the field detail many of the methods which are now used to study sea urchins and other marine invertebrates in the laboratory. These include methods and protocols on imaging, other useful experimental tools for cell, developmental biology research, variety of molecular biological methods, and strategies for utilizing the sea urchin genome. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Developmental Biology of the Sea Urchin and other Marine Invertebrates: Methods and Protocols seeks to aid scientists in the further study into sea urchins and other marine invertebrates.

This volume critically reviews all previously published work of parasites that interact with krill (order Euphausiacea) updating misconceptions and summarizing the diversity of epibionts, ectoparasites, mesoparasites and endoparasites that interact with these crustaceans. As far as we know, there is a lack of books about parasites of marine crustaceans not targeted to fisheries and aquaculture. Thus, this would be the most complete and integrative monograph of parasites of marine zooplankton and micro nektonic organisms worldwide. Krill form immense aggregations and serve as food for multiple planktonic and nektonic predators playing a crucial role in pelagic food web. Besides, several species are also used for human consumption. For these reasons there is a growing concern about the health issues that krill parasites may impose on other species, including us. This book provides a comprehensive review of parasites of a crustacean order that can extrapolate to potential parasites in other crustacean taxa worldwide.

This text is dedicated to the contributions of women ichthyologists. Three colleagues were selected to represent all women ichthyologists, Ethelwynn Trewavas (ET), Rosemary Lowe-McConnell (Ro) and Eugenie Clark (Genie). All have had distinguished professional careers and have contributed in their own ways to their science. The career of each is highlighted by a personal interview with one of the editors of the volume, a bibliography of their lifetime publications, and a biography of their careers. Questions of historical inequities and current controversies in the treatment of women ichthyologists by their peers are raised and addressed by the women themselves. The personal and professional influences of these three women, and other women ichthyologists, are highlighted. A survey article by Pat Brown brings a number of women ichthyologists to the attention of a broader audience, and points the way for a more comprehensive historical consideration of the accomplishments and contributions of women ichthyologists. The volume continues with 16 solicited and contributed papers. ET's studies of taxonomy and life history are echoed in papers on the taxonomy and systematics of marine angelfishes, and of freshwater bitterlings, a review of reproduction in the North Atlantic ichthyofauna, and a comparison of reproductive styles and systematics of African minnows. Ro's studies on ecology, life history and behaviour are paralleled by papers on growth and metabolism in piranha, the community structure in tide pool fishes, and the social system and reproductive patterns in groupers. Genie's pioneering work on sexual roles and sex change, and her field studies of the behaviour of marine fishes are reflected in papers on gonadal structure and environmental sex determination in brook lamprey, sexual patterns in hawkfish, reproduction and systematics in phallostethids, gonadal structure and systematics in gobiids, reproductive and predator avoidance behaviour in razorfish, early ontogeny of an African mouth brooder, and alternative life histories in killifish.

Insects are far and away the largest group of animals on earth, with over a million described species, and they occupy a wide range of ecological niches - they may be herbivores, predators, parasites or decomposers. Some are of particular economic importance as pests of agriculture and forestry, as vectors of animal and human disease, or as species of interest to wildlife conservation, so an understanding of the processes determining their numbers is of considerable practical value. Entomologists have played a leading role in developing a theoretical basis to population ecology, but we still do not have adequate experimental and observational proof for many of the theoretical ideas that have been proposed. As a result, the subject has been beset with arguments for more than 50 years. This volume attempts to reconcile some of those controversies, while also reviewing the state of our knowledge at the end of the 20th century. The editors have drawn together views which reflect the full range of opinions on how natural populations are stabilized. The book covers the main alternative views in population theory and contains recent field studies of insect populations. This Royal Entomological Society Symposium volume should be of interest to all entomologists and ecologists, particularly those who wish to know more about population dynamics.

Despite the best efforts of many and despite landmark discoveries and experimental ingenuity, challenges in the pursuit of research related to olfactory receptors (ORs) continue to exist. In Olfactory Receptors: Methods and Protocols, experts in the field contribute chapters that serve to address these challenges. The volume consists of several sections: knowledge dissemination of ORs, theoretical assessments of OR structure and function, as well as development and use of expression systems and experimental functional analysis. Written in the highly successful Methods in Molecular Biology (TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Concise and practical, Olfactory Receptors: Methods and Protocols seeks to aid researchers in furthering the knowledge of olfaction and moving us ever closer to the thrilling discoveries that will follow.

The goal of this book is to search for a balance between simple and analyzable models and unsolvable models which are capable of addressing important questions on population biology. Part I focusses on single species simple models including those which have been used to predict the growth of human and animal population in the past. Single population models are, in some sense, the building blocks of more realistic models -- the subject of Part II. Their role is fundamental to the study of ecological and demographic processes including the role of population structure and spatial heterogeneity -- the subject of Part III. This book, which will include both examples and exercises, is of use to practitioners, graduate students, and scientists working in the field.

The basic goal of the volume is to compile the most up to date research on how high altitude affects the behavior, ecology, evolution and conservation status of primates, especially in comparison to lowland populations. Historically, the majority of primate studies have focused on lowland populations. However, as the lowlands have been disappearing, more and more primatologists have begun studying populations located in higher altitudes. High altitude populations are important not only because of their uniqueness, but also because they highlight the range of primate adaptability and the complex variables that are involved in primate evolution. These populations are good examples of how geographic scales result in diversification and/or speciation. Yet, there have been very few papers addressing how this high altitude environment affects the behavior, ecology, and conservation status of these primates. "

Members of the genus Campylobacter are commonly found in the gastrointestinal tract of mammals and birds, and can be commensal or pathogenic in nature. In this book, internationally recognized experts critically review and provide novel insights into important aspects Campylobacter research.

In a world where habitats are constantly changing and the impact of anthropization on the environment is increasingly intense, interactions between human and wildlife are becoming more and more complex. Some species pose problems for human activities while many others need to be helped in order to continue to exist. This book follows the first volume called 'Problematic Wildlife', edited by F.M. Angelici and published by Springer in 2016, which has had considerable success with readers and critics. The volume includes 21 chapters divided into 7 parts devoted specific topics which are approached in a multidisciplinary way. There are both review chapters and specific cases, always bearing in mind the interest for an international audience. The book is useful both for scientists, wildlife specialists, conservationists, zoologists, ecologists, university students, nature managers, and for those who live in contact with wildlife and its problems, such as farmers, shepherds, hunters, urban planners, and staff of parks and nature reserves. Its ultimate goal is to offer scientific and pragmatic approaches to manage each categories of problematic species.

Birds have colonized almost every terrestrial habitat on the planet - from the poles to the tropics, and from deserts to high mountain tops. Ecological and Environmental Physiology of Birds focuses on our current understanding of the unique physiological characteristics of birds that are of particular interest to ornithologists, but also have a wider biological relevance.
An introductory chapter covers the basic avian body plan and their still-enigmatic evolutionary history. The focus then shifts to a consideration of the essential components of that most fundamental of avian attributes: the ability to fly. The emphasis here is on feather evolution and development, flight energetics and aerodynamics, migration, and as a counterpoint, the curious secondary evolution of flightlessness that has occurred in several lineages. This sets the stage for subsequent chapters, which present specific physiological topics within a strongly ecological and environmental framework. These include gas exchange, thermal and osmotic balance, 'classical' life history parameters (male and female reproductive costs, parental care and investment in offspring, and fecundity versus longevity tradeoffs), feeding and digestive physiology, adaptations to challenging environments (high altitude, deserts, marine habitats, cold), and neural specializations (notably those important in foraging, long-distance navigation, and song production).
Throughout the book classical studies are integrated with the latest research findings. Numerous important and intriguing questions await further work, and the book concludes with a discussion of methods (emphasizing cutting-edge technology), approaches, and future research directions.

This book explores both the possibilities and limits of arguments from human nature in the context of human rights. Can the concept of human nature provide a basis for understanding fundamental rights? Is it plausible to justify the claim to universal validity of human rights by reference to human nature? Or does the idea of human rights in its modern, post-1945 manifestation go, in essence, beyond human nature? The essays in this volume introduce naturalistic positions and their concomitant critiques. They address the role that human nature both actually does and potentially may play in forming a foundation for and acting as an exemplification of fundamental rights. Beyond that, they give attention to the challenges caused by Life Sciences. Human nature itself is subject to transformation and transgression in an unprecedented manner. The essays reflect on issues such as reproduction, species manipulation, corporeal autonomy and enhancement. Contributors are jurists, philosophers and political scientists from Germany, Switzerland, Turkey, Poland and Japan.

The successful previous volume on this topic provided a detailed benchwork manual for the most commonly used animal models of acute neurological injuries including cerebral ischemia, hemorrhage, vasospasm, and traumatic brain and spinal cord injuries. Animal Models of Acute Neurological Injuries II: Injury and Mechanistic Assessments aims to collect chapters on assessing these disorders from cells and molecules to behavior and imaging. These comprehensive assessments are the key for understanding disease mechanisms as well as developing novel therapeutic strategies to ameliorate or even prevent damages to the nervous system. Volume 2 examines global cerebral ischemia, focal cerebral ischemia, and neonatal hypoxia-ischemia, as well as intensive sections covering traumatic brain injury and spinal cord injury. Designed to provide both expert guidance and step-by-step procedures, chapters serve to increase understanding in what, why, when, where, and how a particular assessment is used. Accessible and essential, Animal Models of Acute Neurological Injuries II: Injury and Mechanistic Assessments will be useful for trainees or beginners in their assessments of acute neurological injuries, for experienced scientists from other research fields who are interested in either switching fields or exploring new opportunities, and for established scientists within the field who wish to employ new assessments.

Fluorescence in situ Hybridization (FISH) belongs to that special category of well-established molecular biology techniques that, since their inception a few decades ago, have succeeded in keeping a prominent position within the constantly expanding list of laboratory pro- dures for biomedical research and clinical diagnostics. The design simplicity and cost-effectiveness of the early FISH protocols, combined with the signifcant acceleration of discoveries in related technical areas such as fuor- cence microscopy, digital imaging, and nucleic acid technology have prompted the div- sifcation of the original technique into an outstanding number of imaginative and useful applications, and thus have not only held back its outmoding but have also promoted its expansion into different areas of basic and applied research in the post-genomic era. The 34 chapters included in this book aim at portraying the vibrant complexity and diversity of the current FISH protocol landscape, providing cutting-edge examples of va- ous applications for genetic and developmental research, cancer research, reproductive medicine, diagnostic and prognostic purposes, microbial ecology, and evolutionary st- ies. The book is divided in four parts: (I) Core Techniques, (II) Technical Advancements and Novel Adaptations, (III) Translational FISH: Applications for Human Genetics and Medicine, and (IV) Protocols for Model Organisms.

This volume addresses in detail both livestock's role in climate change and the impacts of climate change on livestock production and reproduction. Apart from these cardinal principles of climate change and livestock production, this volume also examines the various strategies used to mitigate livestock-related GHG emissions, and those which can reduce the impacts of climate change on livestock production and reproduction. Presenting information and case studies collected and analyzed by professionals working in diversified ecological zones, the book explores the influence of climate change on livestock production across the globe. The most significant feature of this book is that it addresses in detail the different adaptation strategies and identifies targets for different stakeholders in connection with climate change and livestock production. Further, it puts forward development plans that will allow the livestock industries to cope with current climate changes and strategies that will mitigate the effects by 2025. Lastly, it provides researchers and policymakers several researchable priorities to help develop economically viable solutions for livestock production with less GHG emissions, promoting a cleaner environment in which human beings and livestock can live in harmony without adverse effects on productivity. Given that livestock production systems are sensitive to climate change and at the same are themselves a contributor to the phenomenon, climate change has the potential to pose an increasingly formidable challenge to the development of the livestock sector. However, there is a dearth of scientific information on adapting livestock production to the changing climate; as such, well-founded reference material on sustaining livestock production systems under the changing climate scenarios in different agro-ecological zones of the world is essential. By methodically and extensively addressing all aspects of climate change and livestock production, this volume offers a valuable tool for understanding the hidden intricacies of climatic stress and its influence on livestock production.

The book deals with Diel Vertical Migration (DVM) of zooplankton in oceans and lakes and is the first critical discussion of the literature in 100 years of research. The accent is on photo-response experiments that revealed the physiological fundament unifying migration behaviour in both biotopes. Accelerations in relative changes in light intensity of dawn and dusk are the stimuli that trigger a PhotoBehaviour Mechanisms (PBM) evolved to realise predator evasion and starvation prevention. Physiology and behaviour are tuned to these adaptive goals. A "set of ecological factors" is necessary and an algorithm shows the operation of the "set." However, not only the kinetic component of behaviour is based on light, also orientation but now the angular light distribution is responsible. Contrast orientation as in Daphnia may also hold for other animals, for example, Euphausia.The application of the PBM in lakes and oceans is demonstrated amongst other for the vertical movements of Sound Scattering Layers. These layers move faster, slower or as fast as an isolume which was a problem for the decennia long explanation that migrating animals followed an optimal light intensity. The enigma was solved. Using time series of changes in population size, egg ratios, development times and death rates due to predation by juvenile fish, the influence of DVM on population dynamics was analysed. Finally, covering the flow of matter in the traditional food web by a network of information transitions illustrates the controlling function of infochemicals, such as fish kairomones.

This volume represents a comprehensive examination of the newly recognized callimico/marmoset clade, which includes the smallest anthropoid primates on earth. It will explore these diminutive primates in their entirety, with sections on phylogeny, taxonomy and functional anatomy, behavioral ecology, reproductive physiology, as well as address critical conservation issues and the need for conservation action. The topics specifically selected for this volume are pivotal for understanding the evolutionary adaptations and divergence of any primate group, and especially one as diverse and curious as this. The discoveries of new taxa over the last fifteen years along with new genetic data have transformed this group from three genera (one with only a distant relationship to the others) and five recognized species, to five closely related genera, comprising at least 22 species. This volume will be the first to synthesize data on these newly recognized taxa.

This volume is an international endeavor, bringing together primary callimico and marmoset researchers from around the globe, including Brazil and the United States as well as Greece, Italy, Switzerland, and Germany. One of the merits of this volume is that it will serve as a readily accessible work that includes the major findings of several key international researchers whose work has not been easily available to English-speaking scholars. In addition, it draws together lab and field researchers, geneticists, anatomists, and behaviorists in an integrated volume that will provide the most detailed and thorough work on either callimicos or marmosets to date. This volume will also provide a timely forum for identifying future avenues of action necessary for more fully understanding and protecting this intriguing primate radiation.