This stimulating analysis reviews the broad potential of animal models to foster a deeper understanding of human pathology, strengthen connections between genetic and behavioral studies, and develop more effective treatments for mental disorders. Widely-studied and lesser-used species are examined in models that capture features along the continuum of normative and pathological behavior. The models highlight genetic causes of core features, or endophenotypes, of developmental, internalizing, and externalizing disorders, as well as dementia. Expert contributors address questions ranging from how suitable species are chosen for study to the costs and benefits of using inbred versus outbred strains, and the effects of housing environment on subject animals. Larger issues addressed include how to evaluate the applicability of animal behavioral models to the human condition and how these models can harness emerging molecular technologies to further our understanding of the genetic basis of mental illness. Included in the coverage: Mating and fighting in Drosophila. Attachment and social bonding. Impulsivity in rodents and humans. Animal models of cognitive decline. Animal models of social cognition. Future directions for animal models in behavioral genetics. A detailed map of where this evolving field is headed, Animal Models of Behavior Genetics shows geneticists, molecular biologists, and cognitive neuroscientists paths beyond established concepts toward a more knowledgeable and collaborative future.

This book examines how biotechnology can improve livestock breeding and farming, and thereby also animal products. In the first chapters the reader will discover which techniques and approaches are currently used to improve animal breeding, animal health and the value of animal products. Particular attention is given to reproduction techniques, animal nutrition and livestock vaccines that not only enhance animal health but also have a significant effect on human health by ensuring safe food procurement and preventing zoonotic diseases. In addition, modern biotechnology can increase not only productivity but also the consistency and quality of animal food, fiber and medical products. In the second part of the book, issues such as how animal biotechnology could affect the environment and the important topic of animal waste management are explored. In the concluding chapter, the authors discuss future challenges related to animal biotechnology. This work will appeal to a wide readership, from scientists and professionals working in animal production, to those in farm animal management and veterinary science.

This fascinating reference book delves into the origins of the vernacular and scientific names of sharks, rays, skates and chimeras. Each entry offers a concise biography, revealing the hidden stories and facts behind each species' name. Full of interesting facts and humorous titbits, the authors' extensive research and detective work has made this book a comprehensive source of knowledge on everyone associated with the naming of a species. A fascinating resource for anyone with an interest in sharks, from curious naturalist to professional ichthyologist, it is an essential addition to the library of anyone wishing to satisfy those tickling questions on the mysteries behind the names. Sometimes a name refers not to a person but to a fictional character or mythological figure. Eptatretus eos is named after the Greek goddess of the dawn in reference to the pink colouring of the hagfish. The Chilean Roundray Urotrygon cimar, named after Centro de Investigacion en Ciencias del Mar y Limnologia in honour of its 20th anniversary, and the Angular Angelshark Squatina Guggenheim, named after the John Simon Guggenheim Memorial Foundation, are both named after institutions. The Whiteleg Skate Amblyraja taaf is just a shorthand way of describing a toponym - Territoire des Terres australes et antarctiques francaises. There are also entries which are light-hearted such as the one for a lady who told us "that decoration of her cakes have included roughtail skate Bathyraja trachura, red abalone Haliotis rufescens, and chinook salmon Oncorhynchus tshawytscha." Following the success of their previous Eponym Dictionaries, the authors have joined forces to give the Elasmobranch group of fishes a similar treatment but they have also included the describers and authors of the original descriptions of the fishes involved, in addition to those names that are, or appear to be, eponyms. They have tracked down some 850 names of living as well as dead people. Of these half are eponyms after people who have fish named after them and may also have described a fish or fishes. The other half are ichthyologists, marine biologists and other scientists who have become involved in the description and naming of sharks, rays, skates and chimeras. For each person mentioned there is brief, pithy biography. Additionally there are some 50 entries for what sound like eponyms but turned out not to have any connection to a person, such as the Alexandrine Torpedo is named after the city in Egypt and not Alexander the Great. In some cases these are a reminder of the courage of scientists whose dedicated research in remote locations exposed them to disease and even violent death. The eponym ensures that their memory will survive, aided by reference works such as this highly readable dictionary. Altogether 1,577 fishes are listed.

Amphibian species around the world are unusually vulnerable to a variety of threats, by no means all of which are properly understood. Volume 11 in this major series is published in parts devoted to the causes of amphibian decline and to conservation measures in regions of the world. This volume, Part 4 in the series, is concerned with Southern Europe (Italy, Malta, Croatia, Slovenia, Serbia, Montenegro, Bosnia and Herzegovina, Macedonia, Albania, Greece, Romania, Hungary, Bulgaria, Turkey, and Cyprus). Each chapter has been written by experts from each country, describing the ecological background and the conservation status of affected species, with an emphasis on native species. As well as infectious diseases and parasites, threats take the form of introduced and invasive species, pollution, destruction and alteration of habitat, and climatic change. These are discussed as they affect each species. All these countries have monitoring schemes and conservation programs, whose origins and activities are described. Recommendations for action are also made. Edited by leading scholars in the field, Volume 11, when complete, will provide a definitive survey of the amphibian predicament and a stimulus to further research with the objective of arresting the global decline of an entire class of animal.

Insect science is fast changing as insects are evolving to a plethora of newer chemical molecules, climate change, management tactics and transformation of the landscapes. Through the International Conference, the editors have attempted to gather together newer aspects of Insect Sciences like Insect Taxonomy, DNA Barcoding, Physiology, Toxicology, Vectors and their Management, Molecular Biology, RNA interference in Pest Management, Semiochemicals and Pest Management using Host Plant Resistance and Biological Control appropriated especially for the developing world. Both basic and applied aspects of insect science have been included to stimulate comprehensive studies on insect science. The book not only deals with insect science but also environmental and ecological aspects in the hope that the book will be of immense use to students, researchers, extension workers, planners, administrators, farmers and other end users. The Chapters on diversified aspects of Insect Science are contributed by leading scientists for the coming 21st century in which entomology is witnessing a dramatic advancement in management of pests through in-depth investigations. The dimensions of Insect Science covered in the book are pest management approaches that can be adopted worldwide with ascent on sustainability.

This book provides a comprehensive and up-to-date review of the ecology of coral reef fishes presented by top researchers from North America and Australia. Immense strides have been made over the past twenty years in our understanding of ecological systems in general and of reef fish ecology in particular. Many of the methodologies that reef fish ecologists use in their studies will be useful to a wider audience of ecologists for the design of their ecological studies. Significant among the impacts of the research on reef fish ecology are the development of nonequilibrium models of community organization, more emphasis on the role of recruitment variability in structuring local assemblages, the development and testing of evolutionary models of social organization and reproductive biology, and new insights into predator-prey and plant-herbivore interactions.

This volume of "Advances in Insect Physiology" contains comprehensive interdisciplinary reviews on basic and practical aspects relevant to Insect Midgut and Insecticidal Proteins.
Contains important, comprehensive and in-depth reviewsAn essential reference source for invertebrate physiologists and neurobiologists, entomologists, zoologists, and insect biochemistsFirst published in 1963, this serial is ranked second in the highly competitive ISI category of Entomology

The Inside Out of Flies is a look under the bonnet at the astonishing mechanics of fly anatomy. Erica McAlister reveals the engineering miracles embodied in numerous species of fly and some of the fascinating implications they hold for human technology. Discover the physics of the mysterious 'scuba diving fly', marvel at the venomous horse fly larvae which prey on frogs, and glimpse the golden ratio in these creatures' spiral flight patterns. McAlister touches on the emerging field of biomimetics - the study of evolutionary adaptations to devise new technology - and anticipates everything from medical needles based on the mosquito's proboscis to hearing aids inspired by Ormia ochracea, a tiny fly with ears on its thorax. At every juncture she uncovers unique and surprising science lessons encapsulated in the form and function of the humble fly.

Kisspeptin has been shown to be both necessary and sufficient for activation of the reproductive axis, during puberty and later in adulthood. This makes kisspeptin a fundamental component of the reproductive axis. Kisspeptin has been deemed the single most potent stimulator of GnRH neurons yet known. The importance of kisspeptin has been documented in humans as well as non-human animal models, ranging from monkeys, sheep, and rodents to numerous fish species, thus signifying a highly conserved nature of its reproductive function. Importantly, kisspeptin neurons seem to mediate many of the regulatory effects of other signals, whether they are metabolic, circadian, hormonal, or stress. This places kisspeptin neurons in a unique position to be key nodal points and conduits for conveying numerous endogenous and exogenous signals to the reproductive axis.

This book presents a selection of new insights in understanding and mitigating impacts on wildlife and their habitats. Topics such as, species behaviour and responses; collision risk and fatality estimation; landscape features and gradients, are considered. Other chapters in the book cover the results of current research on mitigation; compensation; effectiveness of measures; monitoring and long-term effects; planning and siting. Examples are given of current research on shutdown on demand and curtailment algorithms. By identifying what we have learned so far, and which predominate uncertainties and gaps remain for future research, this book contributes to the most up to date knowledge on research and management options. This book includes presentations from the Conference on Wind Energy and Wildlife impacts (CWW15), March 2015, hosted by the Berlin Institute of Technology, which offered a platform to national and international participants to showcase the current state of knowledge in wind energy's wildlife implications.

The study of animal communication has led to significant progress in our general understanding of motor and sensory systems, evolution, and speciation. However, one often neglected aspect is that signal exchange in every modality is constrained by noise, be it in the transmission channel or in the nervous system. This book analyses whether and how animals can cope with such constraints, and explores the implications that noise has for our understanding of animal communication. It is written by leading biologists working on different taxa including insects, fish, amphibians, lizards, birds, and mammals. In addition to this broad taxonomic approach, the chapters also cover a wide array of research disciplines: from the mechanisms of signal production and perception, to the behavioural ecology of signalling, the evolution of animal communication, and conservation issues. This volume promotes the integration of the knowledge gained by the diverse approaches to the study of animal communication and, at the same time, highlights particularly interesting fields of current and future research.

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This book reviews some of the most important scientific and philosophical theories concerning the nature of mind and consciousness. Current theories on the mind-body problem and the neural correlates of consciousness are presented through a series of biographical sketches of the most influential thinkers across the fields of philosophy of mind, psychology and neuroscience. The book is divided into two parts: the first is dedicated to philosophers of mind and the second, to neuroscientists/experimental psychologists. Each part comprises twenty short chapters, with each chapter being dedicated to one author. A brief introduction is given on his or her life and most important works and influences. The most influential theory/ies developed by each author are then carefully explained and examined with the aim of scrutinizing the strengths and weaknesses of the different approaches to the nature of consciousness.

This authoritative volume explores advances in the techniques used to measure percutaneous penetration of drugs and chemicals to assess bioavailability and bioequivalence and discusses how they have been used in clinical and scientific investigations. Seven comprehensive sections examine topics including in vitro drug release, topical drugs products, clinical studies, and guidelines and workshop reports, among others. The book also describes how targeted transdermal drug delivery and more sophisticated mathematical modelling can aid in understanding the bioavailability of transdermal drugs. The first edition of this book was an important reference guide for researchers working to define the effectiveness and safety of drugs and chemicals that penetrated the skin. This second edition contains cutting-edge advances in the field and is a key resource to those seeking to define the bioavailability and bioequivalence of percutaneously active compounds to improve scientific and clinical investigation and regulation.

Animal models and tests have become increasingly important for biomedical research, enabling a better understanding of pathogenic pathways involved in various human disorders. Over the last decades, zebrafish (Danio rerio) have become a very popular model organism in biomedical research. Recently, this fish has entered the waters of neuroscience and biological psychiatry, quickly becoming an indispensable model species in this field. With a high genetic homology to humans (~75% based on coding regions), it is not surprising that humans and fish are very similar physiologically (and behaviorally). Therefore, it should not come as a surprise that zebrafish can be an excellent model of human neuropsychiatric disorders. While some classical psychiatrists may not too easily be persuaded by this generalization, the current book "The rights and wrongs of zebrafish: principles of behavioral phenotyping and CNS disease modeling" explains, in a domain-by-domain manner, how exactly zebrafish models can be used to target a wide range of human brain disorders and aberrant phenotypes. The contributors to this book are leading international scholars whose work spearheads innovative zebrafish neuroscience research around the world. Written by top experts in the field, this book makes for a useful, balanced and up-to-date reading that outlines the use of zebrafish to study the pathological mechanisms underlying neuropsychiatric disorders.

Neither pest management nor resistance management can occur with only an understanding of pest biology. For years, entomologists have understood, with their use of economic thresholds, that at least a minimal use of economics was necessary for proper integrated pest management. IRM is even more complicated and dependent on understanding and using socioeconomic factors. The new edition of "Insect Resistance Management" addresses these issues and much more.

Many new ideas, facts and case studies have been developed since the previous edition of "Insect Resistance Management" published. With a new chapter focusing on Resistance Mechanisms Related to Plant-incorporated Toxins and heavily expanded revisions of several existing chapters, this new volume will be an invaluable resource for IRM researchers, practitioners, professors and advanced students. Authors in this edition include professors at major universities, leaders in the chemical and seed industry, evolutionary biologists and active IRM practitioners. This revision also contains more information about IRM outside North America, and a modeling chapter contains a large new section on uncertainty analysis, a subject recently emphasized by the U.S. Environmental Protection Agency. The final chapter contains a section on insecticidal seed treatments.

No other book has the breadth of coverage of "Insect Resistance Management, 2e." It not only covers molecular to economic issues, but also transgenic crops, seed treatments and other pest management tactics such as crop rotation. Major themes continuing from the first edition include the importance of using IRM in the integrated pestmanagement paradigm, the need to study and account for pest behavior, and the influence of human behavior and decision making in IRM.
Provides insights from the history of insect resistance management (IRM) to the latest scienceIncludes contributions from experts on ecological aspects of IRM, molecular and population genetics, economics, and IRM social issuesOffers biochemistry and molecular genetics of insecticides presented with an emphasis on recent researchEncourages scientists and stakeholders to implement and coordinate strategies based on local social conditions"