Water - and its governance - is becoming a global concern partly because it is turning into a goods in short supply, with devastating effects on literally billions of people, but also because it is the "carrier" ofglobal warming; whether through irregular weather patterns or through flooding, water is how global warming will be 'felt'. The lion's share of the globally available fresh water resources is to be found in transboundary systems. In spite of its significance, the generated knowledge on how to deal with transboundary waters is weak and leaves policy makers with seemingly unavoidable, trade-off dilemmas and prioritizations, often with detrimental effects. In order to disentangle this predicament this volume works with one case: the Lower Mekong Basin and covers state-of-the-art academic and practitioners' knowledge and hence appeals to a wide audience. The topic this volume addresses is situated in the nexus ofan IR- (International Relations) approach focussing on transboundary politics and its inclination to remain within the sphere of state sovereignty and national interest on the one hand, and Development studies, with its imperatives on participation, planning, and intervention, on the other.The dilemma, we argue, of better understanding transboundary water management lies in how to understand how these two rationalities can be simultaneously nurtured.
"Audience: "This book will be relevant to scholars, as it provides cutting-edge research, and students, since it covers the primary debates in the field, interested in resource management, regional politics, and development issues in the area. It also addresses the global debate on transboundary water management and presents an in-depth case of one of the globally most sophisticated attempts at pursuing sustainable river basin management. Finally, practitioners and policymakers would benefit greatly because all contributions have explicit policy relevance, launching suggestion on improvements in water management.

Given the critical importance of insect immunology in insect vector-parasite interactions and vector control, biological control of agricultural insect pests, and other key areas of entomological research and practice, a new comprehensive work summarizing recent breakthroughs in this rapidly expanding field is sorely needed. This work will constitute the first book-length publication on the topic of insect immunology since 1991, complimenting earlier works by offering a fresh perspective on current research. Interactions of host immune systems with both parasites and pathogens will be presented as well as the genomics and proteomics approaches which have been lacking in other publication.
* Encompasses the most important topics of insect immunology including mechanisms, genes, proteins, evolution and phylogeny
* Provides comprehensive coverage of topics important to medical researchers including Drosophila as a model for studying cellular and humoral immune mechanisms, biochemical mediators of immunity, and insect blood cells and their functions
* Most up-to-date information published with contributions from international leaders in the field

This is the first book entirely dedicated to Intravital Microscopy. It provides the reader with a broad overview of the main applications of Intravital Microscopy in various areas of the biomedical field. The book contains accurate descriptions of the state of the art methodologies used to image various organs at different level of resolution, ranging from whole tissue down to sub-cellular structures. Moreover, it is an extremely valuable guide to scientists that want to adopt this powerful technique and do not have experience with animal models and microscopy.

Recently, there has been an increased interest in research on personality, temperament, and behavioral syndromes (henceforth to be referred to as personality) in nonhuman primates and other animals. This follows, in part, from a general interest in the subject matter and the realization that individual differences, once consigned to error terms in statistical analyses, are potentially important predictors, moderators, and mediators of a wide variety of outcomes ranging from the results of experiments to health to enrichment programs. Unfortunately, while there is a burgeoning interest in the subject matter, findings have been reported in a diverse number of journals and most of the methodological and statistical approaches were developed in research on human personality.

The proposed volume seeks to gather submissions from a variety of specialists in research on individual differences in primate temperament, personality, or behavioral syndromes. We anticipate that chapters will cover several areas. The first part of this edited volume will focus on methodological considerations including the advantages and disadvantages of different means of assessing these constructs in primates and introduce some statistical approaches that have typically been the domain of human personality research. Another part of this edited volume will focus on present findings including the physiological and genetic bases of personality dimensions in primates; the relationship between personality and age; how personality may moderate or impact various outcomes including behavior, health, and well-being in captive and non-captive environments. For the third part of the volume we hope to obtain summaries of the existing work of the authors on the evolutionary important of personality dimensions and guideposts for future directions in this new and exciting area of research."

This exciting volume offers an up-to-date tour of current trends in the neurobiology of memory while saluting Raymond Kesner's pioneering contributions to the field as a theorist and researcher, teacher and mentor. Starting with his signature chapter introducing the Attribute Model of Memory, the first half of the book focuses on the central role of the hippocampus in processing dimensions of space and time, and branches out to memory system interactions across brain structures. Later chapters apply the attribute model to multiple functions of memory in learning, and to specific neurological contexts, including Huntington's disease, traumatic brain injury, and Fragile X. As a bonus, the book concludes with an essay on Kesner's life and work, and reminiscences by colleagues. Among the topics covered: How the hippocampus supports the spatial and temporal attributes of memory. Self-regulation of memory processing centers of the brain. Multiple memory systems: the role of Kesner's Attribute Model in understanding the neurobiology of memory. Pattern separation: a key processing deficit associated with aging? * Prefrontal cortex and basal ganglia attributes underlying behavioral flexibility. Memory disruption following traumatic brain injury. Cognitive neuroscientists, neuropsychologists, gerontologists, psychiatrists, and neurobiologists will find The Neurobiological Basis of Memory both enlightening and inspiring--much like Kesner himself.

This timely book documents marvelous brachiopod fossils from the Palaeozoic-Mesozoic transition of South China. Numerous beautiful pictures and detailed descriptions (specifically the measurements of body size) of brachiopod species are presented. Systematic discussion on the evolution of brachiopod biodiversity and morphological features across the critical interval is not only extremely important for paleontologists to understand the marine ecosystem evolution from the Palaeozoic to the Mesozoic, but also attractive for students who need to know about the end-Permian mass extinction. The book distinguishes itself from other studies by its detailed study of the taxonomy, biodiversity and paleoecology of Permian-Triassic brachiopods from different palaeogeographic facies, especially from the deep-water environment in South China. The book also offers a unique study of the response of morphological features of brachiopods to palaeoenvironmental changes, providing insights for the process of Permian-Triassic crisis.

The influence of Bernard Dussart's contributions to limnology in general as well as to freshwater copepodology in particular can hardly be overestimated. From 1945 until his decease late 2008, he has devoted more than 60 years of his life to studying freshwater bodies and their inhabitants. Next to his 200+ scientific papers, his frequent travels brought him all over the world, where he invariably left an inheritage of enhanced interest in problems of freshwater biology and management. The contributions in this book show the progress of research on the Copepoda found in continental waters and in part continue along the lines B. Dussart has set out: a worthy tribute to one of the very nestors of copepodology of fresh waters.

Assembles a collection of experts to provide a current account of different approaches (e.g., traditional, comparative and experimental) being applied to study mobility. Moreover, the book aims to stimulate new theoretical perspectives that adopt a holistic view of the interaction among intrinsic (i.e. skeletal) and extrinsic (i.e. environmental) factors that influence differential expression of mobility. Since the environment undoubtedly impacts mobility of a wide variety of animals, insights into human mobility, as a concept, can be improved by extending approaches to investigating comparable environmental influences on mobility in animals in general. The book teases apart environmental effects that transcend typical categories (e.g., coastal versus inland, mountainous versus level, arboreal versus terrestrial). Such an approach, when coupled with a new emphasis on mobility as types of activities rather than activity levels, offers a fresh, insightful perspective on mobility and how it might affect the musculoskeletal system.

This volume focuses on defining the unique attributes of using the zebrafish cancer model for discovering important pathways and potential drug targets for the treatment of human cancers. Using the zebrafish model, the volume explores oncogene and tumor suppressor discovery, chemical genetic approaches, genomics, epigenetics, cancer imaging, and cell transplantation. Contributed chapters come from the most prominent laboratories working in this field, which provides a unique perspective on zebrafish models from a wide spectrum of the research community. In addition, the book offers a detailed analysis of the most current research in the area for specific zebrafish cancer models, including T cell leukemia, rhabdomyosarcoma, liver and pancreatic cancer, melanoma, neuroblastoma, germ cell tumors, and malignant peripheral sheath tumors. A chapter is also dedicated to the development and utilization of other piscine models of cancer. The compilation of chapters in the volume culminates into a comprehensive and definitive text on zebrafish and cancer, providing a much needed resource on the powerful attributes of the zebrafish model system.

Normative Biology, Husbandry, and Models, the third volume in the four volume set, The Mouse in Biomedical Research, encompasses 23 chapters whose contents provide a broad overview on the laboratory mouse's normative biology, husbandry, and its use as a model in biomedical research. This consists of chapters on behavior, physiology, reproductive physiology, anatomy, endocrinology, hematology, and clinical chemistry. Other chapters cover management, as well as nutrition, gnotobiotics and disease surveillance. There are also individual chapters describing the mouse as a model for the study of aging, eye research, neurodegenerative diseases, convulsive disorders, diabetes, and cardiovascular and skin diseases. Chapters on imaging techniques and the use of the mouse in assays of biological products are also included.

Diplomacy, Funding and Animal Welfare is a practical guide to the best diplomatic and negotiation practices needed to convince governments and international institutions to effectively protect animals, which also introduces new approaches to fundraising. Animal protection advocates are prepared for speaking to diplomats and government officials in any setting, and to combatants in war zones. The book mainly focuses on approaching local and national governments, the United Nations system, the international Red Cross movement and systems related to other international organizations that can help animals, often in surprising ways. The reader will learn the rules of "diplomatic protocol", and much about the rules and procedures of major international bodies. To provide balance and real world relevance, the guide draws on a compilation of the author's extensive activities across a range of development, animal welfare, emergency management and climate issues in government and in the NGO world, as well as interviews with scholars and officials from NGOs, diplomatic missions, the United Nations, the Red Cross, governments and corporations.