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Fluorescence in situ Hybridization (FISH) - Protocols and Applications (Hardcover, 2010)
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Fluorescence in situ Hybridization (FISH) - Protocols and Applications (Hardcover, 2010)
Series: Methods in Molecular Biology, 659
Expected to ship within 10 - 15 working days
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Fluorescence in situ Hybridization (FISH) belongs to that special
category of well-established molecular biology techniques that,
since their inception a few decades ago, have succeeded in keeping
a prominent position within the constantly expanding list of
laboratory pro- dures for biomedical research and clinical
diagnostics. The design simplicity and cost-effectiveness of the
early FISH protocols, combined with the signifcant acceleration of
discoveries in related technical areas such as fuor- cence
microscopy, digital imaging, and nucleic acid technology have
prompted the div- sifcation of the original technique into an
outstanding number of imaginative and useful applications, and thus
have not only held back its outmoding but have also promoted its
expansion into different areas of basic and applied research in the
post-genomic era. The 34 chapters included in this book aim at
portraying the vibrant complexity and diversity of the current FISH
protocol landscape, providing cutting-edge examples of va- ous
applications for genetic and developmental research, cancer
research, reproductive medicine, diagnostic and prognostic
purposes, microbial ecology, and evolutionary st- ies. The book is
divided in four parts: (I) Core Techniques, (II) Technical
Advancements and Novel Adaptations, (III) Translational FISH:
Applications for Human Genetics and Medicine, and (IV) Protocols
for Model Organisms.
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