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Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Neurosciences
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Morphogenesis of the Brain in Staged Rhesus Monkey Embryos (Paperback)
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Morphogenesis of the Brain in Staged Rhesus Monkey Embryos (Paperback)
Series: Advances in Anatomy, Embryology and Cell Biology, 91
Expected to ship within 10 - 15 working days
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During development two strongly interrelated processes can be
discerned in the central nervous system (eNS), namely morphogenesis
and histogenesis. Most neuroembryological studies deal with
histogenetic features virtually with- out any morphological
elucidation. It must be stressed, however, that histogen- etic
investigations should be based upon a thorough knowledge of
morphogene- sis. This holds especially for the forebrain, which
during development is sub- jected to drastic transformations,
particularly when only two-dimensional sec- tions are used.
Therefore the present study on morphogenesis forms the first part
of a research project on the ontogenesis of the brain in the rhesus
monkey. The second part (Gribnau and Geijsberts 1984) will deal
with the early histogene- sis of the forebrain. The first
recognizable precursor of the eNS in vertebrates is the neural
plate, which, after the formation of the germ layers, is induced in
the ectoderm. The lateral margins of the neural plate start to
rise, forming a neural groove. Eventu- ally, they meet dorsally in
the midline and fuse, resulting in the formation of the neural
tube. The ultimate sites of closure at either end of the neural
tube are called the anterior and posterior neuropores. Before the
closure of the anterior neuropore, which precedes that of the
posterior neuropore, the anlage of the eNS can be divided into a
narrow elongated caudal part, the future spinal cord, and a wider
rostral part, the precursor of the brain.
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