Pharmacodynamic Models of Selected Toxic Chemicals in Man - Volume 2: Routes of Intake and Implementation of Pharmacodynamic Models (Paperback, Softcover reprint of the original 1st ed. 1986)

This report contains the results of a study undertaken by Associated Nuclear Services (ANS) for the Directorate General of Employment, Social Affairs and Education of the Commission of the European Communities (CEC). This study was entitled "Dynamics of Selected Toxic Materials in Man." vii 2 Summary This report presents results from the second phase of a study on the metabolism of selected actual and potential human carcin ogens. In the first phase of this work a comprehensive review of literature relating to the metabolism of these materials was under taken and pharmacokinetic models were proposed to represent that meta bolism. It was suggested that these models, and the reviews on which they were based, would provide information relevant to the development of monitoring programmes and in the interpretation of dose-response data. In the second phase of the study, attention has been concen trated on the implementation of the models proposed for the various substances reviewed, i.e. arsenic, beryllium, cadmium, lead, nickel, chromium, asbestos, benzene, vinyl chloride monomer, benzidine and its congeners, carbon tetrachloride and methyl iodide. However, this programme has been supplemented by an on-going review of the relevant literature on these substances and a detailed analysis of the applica bili ty of the pharmacokinetic models used for the organs of intake, i.e. the lung and gastrointestinal tract."

General

Imprint:	Springer
Country of origin:	Netherlands
Release date:	October 2011
First published:	1986
Authors:	A. D Smith • M.C. Thorne
Dimensions:	235 x 155 x 22mm (L x W x T)
Format:	Paperback
Pages:	418
Edition:	Softcover reprint of the original 1st ed. 1986
ISBN-13:	978-9401083492
Categories:	Books > Medicine > Other branches of medicine > Pharmacology > General Promotions
LSN:	9401083495
Barcode:	9789401083492

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