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Progress in the Chemistry of Organic Natural Products 115 (Hardcover, 1st ed. 2021)
Loot Price: R8,102
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Progress in the Chemistry of Organic Natural Products 115 (Hardcover, 1st ed. 2021)
Series: Progress in the Chemistry of Organic Natural Products, 115
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This book describes current understandings and recent progress into
a varied group of natural products. In the first chapter the role
that total synthesis may play in revising the structures proposed
for decanolides, which are ten-membered lactones found primarily in
fungi, frogs, and termites is presented. The following chapter
presents the development of the intriguing plant-derived
sesquiterpene lactone, thapsigargin, a potent inhibitor of the
enzyme, SERCA (sarco-endoplasmic Ca2+ ATPase), which has potential
as a lead compound to treat cancer. The third chapter covers the
potential of various plant phenolic compounds for treating the
tropical and sub-tropical infectious disease, leishmaniasis. In
addition the volume presents recent advances related to the plant
alkaloid, cryptolepine, which is of particular interest as a lead
for the treatment of malaria, trypanosomiasis, and cancer.
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