In recent years there has been considerable interest in the
diagnosis and understanding of ventricular repolarisation,
particularly the QT interval prolongation and abnormal T and T/U
wave morphology associated with torsades de pointes. Advances in
ion channel cloning have greatly improved our understanding of the
role of ionic channels in mediating cardiac repolarisation.
Unfortunately, it is increasingly recognised that a number of
drugs, both those associated with altering repolarisation, and
others for non-cardiac conditions can increase the propensity for
polymorphic ventricular tachycardia, syncope and even ventricular
fibrillation and sudden death.
In this volume, arrhythmia specialists from St. George's
Hospital Medical School, London discuss the mechanisms behind QT
prolongation and torsades de pointes. They focus particularly on
the risk of individual cardiac and non-cardiac drugs in provoking
long QT syndrome, providing a comprehensive review which will be
useful for all electrophysiologists treating polymorphic
ventricular tachycardias, and will expose important regulatory
issues for pharmaceutical authorities and for the wider medical
community.
General
Imprint: |
Wiley-Blackwell (an imprint of John Wiley & Sons Ltd)
|
Country of origin: |
United Kingdom |
Release date: |
December 2004 |
First published: |
September 2004 |
Authors: |
A.J. Camm
|
Dimensions: |
239 x 166 x 17mm (L x W x T) |
Format: |
Hardcover
|
Pages: |
208 |
Edition: |
New |
ISBN-13: |
978-1-4051-1838-5 |
Categories: |
Books >
Medicine >
Clinical & internal medicine >
Cardiovascular medicine
Promotions
|
LSN: |
1-4051-1838-5 |
Barcode: |
9781405118385 |
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