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Aspartic Acid Proteases as Therapeutic Targets (Hardcover)
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Aspartic Acid Proteases as Therapeutic Targets (Hardcover)
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In this ground-breaking practical reference, the family of aspartic
acid proteases is described from a drug developer's perspective.
The first part provides a general introduction to the family of
aspartic acid proteases, their physiological functions, molecular
structure and inhibition. Parts two to five present various case
studies of successful protease inhibitor drug design and
development, as well as current and potential uses of such
inhibitors in pharmaceutical medicine, covering the major
therapeutic targets HIV-1 protease, renin, beta-secretase,
gamma-secretase, plasmepsins and fungal proteases.
A ready reference aimed primarily at professionals in the
pharmaceutical industry, as well as for anyone studying proteases
and their function.
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