Structure-based Design of Drugs and Other Bioactive Molecules - Tools and Strategies (Hardcover)

In contrast to previous texts focusing on either computational, structural or synthetic methods, this one-of-a-kind guide integrates all three skill sets for a complete picture of contemporary structure-based design.
As a result, this practical book demonstrates how to develop a high-affinity ligand with drug-like properties for any given drug target for which a high-resolution structure exists. The authors, both of whom have successfully designed drug-like molecules that were later developed into marketed drugs, use numerous examples of recently developed drugs to present best practice in structure-based drug design with the novice in mind. By way of a carefully balanced mix of theoretical background and case studies from medicinal chemistry applications, readers will quickly and efficiently master the basic skills of successful drug design.

General

Imprint:	Wiley-VCH Verlag GmbH
Country of origin:	Germany
Release date:	June 2014
First published:	August 2014
Authors:	A.K. Ghosh
Dimensions:	250 x 173 x 29mm (L x W x T)
Format:	Hardcover
Pages:	474
ISBN-13:	978-3-527-33365-3
Categories:	Books > Science & Mathematics > Chemistry > General Books > Medicine > Other branches of medicine > Pharmacology > General Promotions
LSN:	3-527-33365-7
Barcode:	9783527333653

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