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The Role of Oxygen Radicals in Cardiovascular Diseases - A Conference in the European Concerted Action on Breakdown in Human Adaptation - Cardiovascular Diseases, held in Asolo, Italy, 2-5 December 1986 (Paperback, Softcover reprint of the original 1st ed. 1988)
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The Role of Oxygen Radicals in Cardiovascular Diseases - A Conference in the European Concerted Action on Breakdown in Human Adaptation - Cardiovascular Diseases, held in Asolo, Italy, 2-5 December 1986 (Paperback, Softcover reprint of the original 1st ed. 1988)
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Growing experimental evidence is beeing produced in support of the
thesis that lipid pe, oxidation is an important mediator of both
vascular and myocardial tissue derangement. Although the role of
the free-radical system in human cardiovascular pathology remains
speculative, nevertheless the potential implications of such a
system in both pharmacological therapy and prevention of major
cardiovascular diseases, such as myocardial infarction,
cardiomyopathy and arrhythmias, justify the increasing interest of
clinical cardiologists in this research area. Furthermore,
present-day clinical cardiology permits to reproduce in man such
experimental models as ischemia and reperfusion, e.g. during
percutaneous transluminal angioplasty, and even to gain
histological and histochemical access to byoptic myocardial tissue.
Upon above premises the idea of a multidisciplinary discussion
meeting was conceived, aimed to confront clinical expectations with
acquired basic information, and to discuss the validity of
experimental models in the light of pathological and clinical
findings in man. To this purpose, a unique group of experts in the
field of free-radicals, from all over the world, was asked to make
the topic accessible to clinical cardiologists, with the primary
aim of projecting results and ideas towards potential clinical
research; this is, in fact, the object of the European Concerted
Action "Breakdown in Human Adaptation - Cardiovascular Diseases,"
in the frame of which the meeting was held.
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