Genes and Common Diseases presents an up-to-date view of the role
of genetics in modern medicine, reflecting the strengths and
limitations of a genetic perspective. The current shift in emphasis
from the study of rare single gene disorders to common diseases
brings genetics into every aspect of modern medicine, from
infectious diseases to therapeutics. However, it is unclear whether
this increasingly genetic focus will prove useful in the face of
major environmental influences in many common diseases. The book
takes a hard and self-critical look at what can and cannot be
achieved using a genetic approach and what is known about genetic
and environmental mechanisms in a variety of common diseases. It
seeks to clarify the goals of human genetic research by providing
state-of-the art insights into known molecular mechanisms
underlying common disease processes while at the same time
providing a realistic overview of the expected genetic and
physiological complexity.
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