Books > Medicine > Clinical & internal medicine > Musculoskeletal medicine
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Osteoclasts - Morphology, Functions & Clinical Implications (Hardcover)
Loot Price: R3,650
Discovery Miles 36 500
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Osteoclasts - Morphology, Functions & Clinical Implications (Hardcover)
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Osteoclasts are highly specialised cells, derived from the
hematopoietic lineage, that resorb mineralised bone matrix.
Osteoclast precursors can be recruited to the bone remodelling
sites by specific cytokines in the microcellular environment,
including some secreted by osteoblasts, fibroblasts, and
osteocytes. In this book, the authors present current research in
the study of the morphology, functions and clinical implications of
osteoclasts. Topics include osteoclast formation and function and
its risk in skeletal bone disease; the high osteoclastogenic
potential of human osteosarcoma cells; osteoclast biology regarding
Paget's disease and p62 mutations; the role of immuno-skeletal
interface in the regulation of osteoclast formation; and
osteoclasts in patients with neurofibromatosis 1.
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