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Kisspeptin Signaling in Reproductive Biology (Hardcover, 2013 ed.)
Loot Price: R6,664
Discovery Miles 66 640
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Kisspeptin Signaling in Reproductive Biology (Hardcover, 2013 ed.)
Series: Advances in Experimental Medicine and Biology, 784
Expected to ship within 12 - 17 working days
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Kisspeptin has been shown to be both necessary and sufficient for
activation of the reproductive axis, during puberty and later in
adulthood. This makes kisspeptin a fundamental component of the
reproductive axis. Kisspeptin has been deemed the single most
potent stimulator of GnRH neurons yet known. The importance of
kisspeptin has been documented in humans as well as non-human
animal models, ranging from monkeys, sheep, and rodents to numerous
fish species, thus signifying a highly conserved nature of its
reproductive function. Importantly, kisspeptin neurons seem to
mediate many of the regulatory effects of other signals, whether
they are metabolic, circadian, hormonal, or stress. This places
kisspeptin neurons in a unique position to be key nodal points and
conduits for conveying numerous endogenous and exogenous signals to
the reproductive axis.
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