Poly(ADP-Ribose) Polymerase - Methods and Protocols (Hardcover, 3rd ed. 2023)

This detailed volume explores poly(ADP-ribose) polymerases (PARPs) in the biology of eukaryotes and their relevance to human health. Beginning with a section on the detection and quantification of poly(ADP-ribose) polymer (pADPr), the book continues by delving into the identification of protein targets, functional analysis, the poly(ADP-ribosyl)ating pathway in chromatin and genes expression, as well as the use of animal models and PARP1 inhibitor design and testing, and more. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Poly(ADP-Ribose) Polymerase: Methods and Protocols, Third Edition presents essential new and classical methods for studying the pADPr-pathway.

General

Imprint:	Springer-Verlag New York
Country of origin:	United States
Series:	Methods in Molecular Biology, 2609
Release date:	December 2022
First published:	2023
Editors:	Alexei V. Tulin
Dimensions:	254 x 178mm (L x W)
Format:	Hardcover
Pages:	446
Edition:	3rd ed. 2023
ISBN-13:	978-1-07-162890-4
Categories:	Books > Science & Mathematics > Chemistry > General Books > Science & Mathematics > Biology, life sciences > Biochemistry > Enzymology Books > Science & Mathematics > Biology, life sciences > Cellular biology > General
LSN:	1-07-162890-9
Barcode:	9781071628904

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