Ion Channel Localization (Paperback, Softcover reprint of hardcover 1st ed. 2001)

Since the pioneering discoveries of Hodgkin, Huxley, and Katz, it has been clear that specific ion conductance pathways underlie electrical act- ity. Over the ensuing 50 years, there has been ever increasing, and occasi- ally explosive, changes in the scope of efforts to understand ion channel behavior. The introduction of patch clamp technology by Erwin Neher and Bert Sakmann about 20 years ago led to the realization of the great variety of novel ion channel species, and the subsequent revolution in cl- ing has revealed an even greater diversity of the underlying molecular entities. Today, advances in the study of ion channel structure and function c- tinue at a high pace, from angstrom resolution imaging of crystallized ch- nels to their genetic manipulations in animals. In this regard, the field is a balanced one that inquires not only what ion channel entities are there, or how they operate, but also where are these molecular electronic switches? However, this balance is not particularly well presented to the general sci- tific audience or to specialists in the field. There are plenty of wonderful and useful books and monographs, as well as conferences and meetings on v- tually every aspect of ion channel structure and function. However, we are unaware that the channel localization theme has been considered in a u- fied forum.

General

Imprint:	HumanaPress
Country of origin:	United States
Series:	Methods in Pharmacology and Toxicology
Release date:	November 2010
First published:	2001
Editors:	Anatoli Lopatin • Colin G. Nichols
Dimensions:	229 x 152 x 26mm (L x W x T)
Format:	Paperback
Pages:	502
Edition:	Softcover reprint of hardcover 1st ed. 2001
ISBN-13:	978-1-61737-211-7
Categories:	Books > Medicine > Other branches of medicine > Pharmacology > General
LSN:	1-61737-211-0
Barcode:	9781617372117

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