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The Vertebrate Blood-Gas Barrier in Health and Disease - Structure, Development and Remodeling (Hardcover, 1st ed. 2015)
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The Vertebrate Blood-Gas Barrier in Health and Disease - Structure, Development and Remodeling (Hardcover, 1st ed. 2015)
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This comprehensive volume on the blood-gas barrier (BGB) among
vertebrates covers its structure and composition along with aspects
of evolution, bioengineering, and morphometry. The book also
discusses the embryological development of the BGB, including
chronology of events and molecular control in vertebrates;
modulation of the barrier function, including cyclic
stretch-induced increases in alveolar epithelial permeability;
mechanisms of lung vascular/epithelial permeability; transport
mechanisms of the BGB, including sodium transport channels; factors
affecting trans-barrier traffic of fluids, such as chronic
elevation of pulmonary microvascular pressure; stress failure;
regulation and repair in acute lung injury; chronic lung disease;
and lung transportation. Ten authoritative chapters approach the
blood-gas barrier holistically, from basic structure and
development to pathology and treatment. Properties of the BGB are
discussed in the earlier chapters, followed by prenatal and
post-natal development and mechanisms of the healthy BGB. The
latter half of the book delves into the pathology of the BGB,
analyzing common afflictions and exploring options for treatment,
including its alterations during lung transplantation. Intuitively
structured and comprehensive, The Vertebrate Blood-Gas Barrier in
Health and Disease is ideal for researchers and clinicians
interested in pneumology and angiology.
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